Molecular profiling confirms historical immunohistochemistry in acromegaly

in Endocrine-Related Cancer
Authors:
Sylvia L Asa Pathology, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, Ohio, USA

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https://orcid.org/0000-0001-8418-5054
and
Shereen Ezzat Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada

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Correspondence should be addressed to S L Asa: Sylvia.Asa@UHhospitals.org
DOI:
https://doi.org/10.1530/ERC-20-0260
Volume/Issue:
Volume 27: Issue 10
Article Type:
Letter
Page Range:
L1–L2
Online Publication Date:
Oct 2020
Copyright:
© 2020 Society for Endocrinology 2020
Restricted access
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Print ISSN:
1351-0088
Online ISSN:
1479-6821
Copyright:
© 2020 Society for Endocrinology 2020
Received Date:
01 Jul 2020
Accepted Date:
03 Aug 2020
Print Publication Date:
01 Oct 2020
Online Publication Date:
Oct 2020

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  • Ezzat S, Kontogeorgos G, Redelmeier DA, Horvath E, Harris AG & Kovacs K 1995 In vivo responsiveness of morphological variants of growth hormone-producing pituitary adenomas to octreotide. European Journal of Endocrinology 133 686–690. (https://doi.org/10.1530/eje.0.1330686)

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  • Ezzat S, Caspar-Bell GM, Chik CL, Denis MC, Domingue MÈ, Imran SA, Johnson MD, Lochnan HA, Grégoire Nyomba BL, Prebtani A, et al.2019 Predictive markers for postsurgical medical management of acromegaly: a systematic review and consensus treatment guideline. Endocrine Practice 25 379–393. (https://doi.org/10.4158/EP-2018-0500)

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  • Puig-Domingo M, Gil J, Sampedro-Nunez M, Jorda M, Webb SM, Serra G, Pons L, Salinas I, Blanco A, Marques-Pamies M, et al.2020 Molecular profiling for acromegaly treatment: a validation study. Endocrine-Related Cancer 27 375–389. (https://doi.org/10.1530/ERC-18-0565)

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  • Qian ZR, Sano T, Yoshimoto K, Asa SL, Yamada S, Mizusawa N & Kudo E 2007 Tumor-specific downregulation and methylation of the CDH13 (H-cadherin) and CDH1 (E-cadherin) genes correlate with aggressiveness of human pituitary adenomas. Modern Pathology 20 1269–1277. (https://doi.org/10.1038/modpathol.3800965)

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  • Sano T, Rong QZ, Kagawa N & Yamada S 2004 Down-regulation of E-cadherin and catenins in human pituitary growth hormone-producing adenomas. Frontiers of Hormone Research 32 127–132. (https://doi.org/10.1159/000079041)

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  • Xu B, Sano T, Yoshimoto K & Yamada S 2002 Downregulation of E-cadherin and its undercoat proteins in pituitary growth hormone cell adenomas with prominent fibrous bodies. Endocrine Pathology 13 341–351. (https://doi.org/10.1385/ep:13:4:341)

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