Could thyroidectomy be excluded if 18F-FDG-PET suggests benignity for TNIC?

in Endocrine-Related Cancer
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  • 1 Q Wan, Department of Nuclear Medicine, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
  • 2 B Ji, Department of Nuclear Medicine, China-Japan Union Hospital of Jilin University, Changchun, China

Correspondence: Bin Ji, Email:
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We read with interest the article by Rosario et al., which summarized the practical applicability of accessible imaging method in the management of thyroid nodules with indeterminate cytologically (TNIC) (Rosario, et al. 2021). For 18F-FDG-PET, it was stated that “a nodule characterized by low or absent 18F-FDG uptake is considered at a very low risk of malignance”, and “thyroidectomy can be excluded if these tests suggest benignity”. We respectfully want to share a different opinion based on our previous work.


Society for Endocrinology

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