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Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
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Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
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Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
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Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
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Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
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al . 2011 ), and soluble protein factors like HGF, bone morphogenic proteins, insulin-like growth factors, the bone TF RUNX2 ( Akech et al . 2010 , Gherardi et al . 2012 , Hiraga et al . 2012 ), and microRNAs ( Cai et al . 2013 ) in cancer
Department of Breast, Endocrine Tumours and Sarcoma, Karolinska University Hospital, Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Department of Breast, Endocrine Tumours and Sarcoma, Karolinska University Hospital, Stockholm, Sweden
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Department of Breast, Endocrine Tumours and Sarcoma, Karolinska University Hospital, Stockholm, Sweden
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Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden
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tissues and 2 −ΔΔCt in cell lines. Primer sequences are listed in Supplementary Table 1. miRNA expression Total RNA was extracted from cell lines using the mirVana RNA Isolation kit (Applied Biosystems) and cDNA was synthesized using MicroRNA cDNA
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Institute of Pathology and Immunology of the University of Porto (IPATIMUP), Department of Pathology, Portugese Institute of Oncology, Department of Pathology, Rua Roberto Frias s/n, 4200-465 Porto, Portugal
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Institute of Pathology and Immunology of the University of Porto (IPATIMUP), Department of Pathology, Portugese Institute of Oncology, Department of Pathology, Rua Roberto Frias s/n, 4200-465 Porto, Portugal
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Institute of Pathology and Immunology of the University of Porto (IPATIMUP), Department of Pathology, Portugese Institute of Oncology, Department of Pathology, Rua Roberto Frias s/n, 4200-465 Porto, Portugal
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Institute of Pathology and Immunology of the University of Porto (IPATIMUP), Department of Pathology, Portugese Institute of Oncology, Department of Pathology, Rua Roberto Frias s/n, 4200-465 Porto, Portugal
Institute of Pathology and Immunology of the University of Porto (IPATIMUP), Department of Pathology, Portugese Institute of Oncology, Department of Pathology, Rua Roberto Frias s/n, 4200-465 Porto, Portugal
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Expression profile Methylation profile microRNAs profile Function/genes OXPHOS/OXPHOS genes and 16S rRNA Cell–cell adhesion/ CDH1 NA/miRNA-221; miRNA-339; miRNA-183; mir-197 and miRNA-31 Apoptosis/ DAP3 Iodine uptake/ NIS Transcription factors/ TFAM ; NRF-1
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valuable screening modality for MEN1 patients. In the future, distinct micro-RNAs (miRNA) also might become potential tumor or biomarkers for MEN1 screening. Micro-RNAs (miRNA) are important genetic regulators and upregulation or downregulation of
Baylor College of Medicine, Departments of Molecular and Cellular Biology, Radiology, Lester and Sue Smith Breast Center, Houston, Texas, USA
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Baylor College of Medicine, Departments of Molecular and Cellular Biology, Radiology, Lester and Sue Smith Breast Center, Houston, Texas, USA
Baylor College of Medicine, Departments of Molecular and Cellular Biology, Radiology, Lester and Sue Smith Breast Center, Houston, Texas, USA
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progression, which suggests another new intervention method ( Mouw et al . 2014 ). MicroRNAs MicroRNAs (miRNAs) are short, noncoding RNAs that bind to complementary sequences in mRNAs, which results in the suppression of translation and/or degradation of
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of candidate microRNA markers for parathyroid carcinoma . Endocrine 60 246 – 254 ( https://doi.org/10.1007/s12020-018-1551-2 ) 10.1007/s12020-018-1551-2 29453660 Klinge CM 2018 Non-coding RNAs: long non-coding RNAs and microRNAs in
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diseases. I continue to be excited to work on androgen signalling in prostate cancer, but equally excited to have moved into and made contributions in other aspects of the disease, such as the roles of microRNAs, which were unheard of when I started my PhD
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Dame Roma Mitchell Cancer Research Laboratories School of Medicine, University of Adelaide, Adelaide, South Australia 5000, Australia
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2014 Androgen biosynthesis in castration resistant prostate cancer . Endocrine-Related Cancer 21 T67 – T78 . ( doi:10.1530/ERC-14-0109 ). Selth LA Tilley WD Butler LM 2012 Circulating microRNAs: macro-utility as markers of prostate
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Department of Pathology, AP-HP, Hôpital Pitié-Salpétrière, Pierre et Marie Curie Université, Paris, France
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Department of Endocrinology, Center for Rare Adrenal Diseases, AP-HP, Hôpital Cochin, Paris, France
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Department of Endocrinology, Center for Rare Adrenal Diseases, AP-HP, Hôpital Cochin, Paris, France
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MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival . Cell Death and Differentiation 18 974 – 984 . ( https://doi.org/10.1038/cdd.2010.164 ) Alexandrov LB Nik-Zainal S Wedge DC Campbell PJ Stratton
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Department of Genetics and Genome Sciences and Germline High Risk Focus Group, Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
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Non-coding RNAs: long non-coding RNAs and microRNAs in endocrine-related cancers . Endocrine-Related Cancer 25 R259 – R282 . ( https://doi.org/10.1530/ERC-17-0548 ) 10.1530/ERC-17-0548) Mulligan LM 2018 65 YEARS OF THE DOUBLE HELIX