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Assistance Publique – Hôpitaux de Marseille (AP-HM), Hôpital de la Conception, Centre de Référence des Maladies Rares Hypophysaires HYPO, Marseille, France
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Department of Surgery, Region Östergötland, Linköping, Sweden
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pheochromocytomas are rare. About 10% of intra-adrenal tumors metastasize in comparison to almost 40% of extra-adrenal sympathetic PGLs ( Lloyd et al . 2017 ). Tumor histology is a poor predictor of metastatic potential and no scoring system is unequivocally
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response as determined by a scoring system that included weight, patient-assessed health score, Karnofsky score, and tumor-related symptoms, in 14/21 patients who were treated with a total cumulative dose of 360 mCi [ 90 Y-DOTA 0 ,Tyr 3 ]octreotide in three
Department of Surgical Sciences, Rudbeck Laboratory, Department of Cell and Molecular Biology, Department of Biology and Pharmaceutical Botany, Department of Molecular Medicine and Surgery, Department of General, Southern Research Institute, Uppsala University Hospital
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histological signs (capsular or vascular invasion, extreme cytological atypia and presence of confluent necroses) can be used in different scoring systems together with other parameters to histopathologically discriminate tumours with a higher risk of
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were used, high VDR expression was correlated with better BC OS ( Xu et al. 2020 ). IRS is a scoring system used for quantitative evaluation of immunohistochemical stainings and is based on the multiplication of the number of positive cells (0–4) and
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assessment scoring system of 0–10 ( Chamberlain et al. 2003 ). It is the procedure most likely, in our experience (Zalles et al. 2003), to produce evaluable epithelial cells. Ductal lavage probably requires the most time to perform, the most training to
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-based Fluorescence in situ hybridization (FISH) 2 Detection of specific gene in cell nuclei using fluorescence-labeled cDNA as probe Determination of exact copy number of target gene; objective scoring system; reliable and accurate More expensive and time
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Clinic for Endocrinology, Diabetology and Clinical Nutrition, University Hospital Zurich, Zurich, Switzerland
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Endocrine Unit, First Department of Propaedeutic Medicine, Laiko University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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NET Unit, Royal Free Hospital, London, UK
Barts and the London School of Medicine, London, UK
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. Metabolic grading according to SRI or 18 F-FDG PET of ambiguous lesions allows prognostic stratification in metastatic GI-NENs, and the newly introduced NETPET scoring system combining results of 18 F-FDG and SRI-PET can accurately describe the patient
Consortium for the Study of Thyroid Cancer (CECaT), Catalonia, Spain
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Program of Predictive and Personalized Medicine of Cancer, Germans Trias i Pujol Research Institute (PMPPC-IGTP), Barcelona, Spain
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. This can be resolved with the BRAF-like and RAS-like phenotypes defined by the Cancer Genome Atlas Research Network ( Cancer Genome Atlas Research Network 2014 ). The Cancer Genome Atlas Research Network developed a scoring system based on the
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immunohistochemical stains, namely (i) the lack of a general consensus on the cut-off value of staining to classify the specimens as positive or negative; (ii) the use of various scoring systems; (iii) the use of different immunohistochemistry protocols, including
Rotterdam Adrenal Center, Department of Internal Medicine, Department of Pathology, Department of Surgery, Erasmus MC University Medical Center, Rotterdam, The Netherlands
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Rotterdam Adrenal Center, Department of Internal Medicine, Department of Pathology, Department of Surgery, Erasmus MC University Medical Center, Rotterdam, The Netherlands
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Rotterdam Adrenal Center, Department of Internal Medicine, Department of Pathology, Department of Surgery, Erasmus MC University Medical Center, Rotterdam, The Netherlands
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Rotterdam Adrenal Center, Department of Internal Medicine, Department of Pathology, Department of Surgery, Erasmus MC University Medical Center, Rotterdam, The Netherlands
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Rotterdam Adrenal Center, Department of Internal Medicine, Department of Pathology, Department of Surgery, Erasmus MC University Medical Center, Rotterdam, The Netherlands
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Rotterdam Adrenal Center, Department of Internal Medicine, Department of Pathology, Department of Surgery, Erasmus MC University Medical Center, Rotterdam, The Netherlands
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Rotterdam Adrenal Center, Department of Internal Medicine, Department of Pathology, Department of Surgery, Erasmus MC University Medical Center, Rotterdam, The Netherlands
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). Pennanen et al . (2015) recently developed the Helsinki score, which consists of the sum of 3× mitotic rate+5× presence of necrosis+maximum proliferation index. This scoring system was able to diagnose metastatic ACC with 100% sensitivity and 99