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Antoinette S Perry
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Ruth Foley
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Karen Woodson
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Mark Lawler
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Introduction: addressing problems with the clinical management of prostate cancer Prostate cancer (CaP) has a unique set of problems associated with its early detection, diagnosis and treatment that might be aided by the

Article Type:
Review Article
DOI:
https://doi.org/10.1677/erc.1.01184
Volume/Issue:
Volume 13: Issue 2
Free access
Xinyu Wu Department of Pathology, Arthritis and Tissue Degeneration Program, Laboratory of Molecular Biology, Department of Pathology, Department of Urology, NYU Cancer Institute, New York Harbor Healthcare System, Department of Urology, New York University School of Medicine, New York, NY, USA

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Shiaoching Gong Department of Pathology, Arthritis and Tissue Degeneration Program, Laboratory of Molecular Biology, Department of Pathology, Department of Urology, NYU Cancer Institute, New York Harbor Healthcare System, Department of Urology, New York University School of Medicine, New York, NY, USA
Department of Pathology, Arthritis and Tissue Degeneration Program, Laboratory of Molecular Biology, Department of Pathology, Department of Urology, NYU Cancer Institute, New York Harbor Healthcare System, Department of Urology, New York University School of Medicine, New York, NY, USA

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Pradip Roy-Burman Department of Pathology, Arthritis and Tissue Degeneration Program, Laboratory of Molecular Biology, Department of Pathology, Department of Urology, NYU Cancer Institute, New York Harbor Healthcare System, Department of Urology, New York University School of Medicine, New York, NY, USA

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Peng Lee Department of Pathology, Arthritis and Tissue Degeneration Program, Laboratory of Molecular Biology, Department of Pathology, Department of Urology, NYU Cancer Institute, New York Harbor Healthcare System, Department of Urology, New York University School of Medicine, New York, NY, USA
Department of Pathology, Arthritis and Tissue Degeneration Program, Laboratory of Molecular Biology, Department of Pathology, Department of Urology, NYU Cancer Institute, New York Harbor Healthcare System, Department of Urology, New York University School of Medicine, New York, NY, USA
Department of Pathology, Arthritis and Tissue Degeneration Program, Laboratory of Molecular Biology, Department of Pathology, Department of Urology, NYU Cancer Institute, New York Harbor Healthcare System, Department of Urology, New York University School of Medicine, New York, NY, USA
Department of Pathology, Arthritis and Tissue Degeneration Program, Laboratory of Molecular Biology, Department of Pathology, Department of Urology, NYU Cancer Institute, New York Harbor Healthcare System, Department of Urology, New York University School of Medicine, New York, NY, USA

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Zoran Culig Department of Pathology, Arthritis and Tissue Degeneration Program, Laboratory of Molecular Biology, Department of Pathology, Department of Urology, NYU Cancer Institute, New York Harbor Healthcare System, Department of Urology, New York University School of Medicine, New York, NY, USA

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Introduction Prostate cancer (PCa) is the most common male-specific cancer in most western countries including the United States. An important cause of morbidity and mortality in PCa is skeletal metastasis; the pathogenesis of bone metastasis is

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-12-0285
Volume/Issue:
Volume 20: Issue 4
Free access
Jason M D'Antonio Department of Urology, Department of Oncology, Brady Urologic Institute
Department of Urology, Department of Oncology, Brady Urologic Institute

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Donald J Vander Griend Department of Urology, Department of Oncology, Brady Urologic Institute
Department of Urology, Department of Oncology, Brady Urologic Institute

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John T Isaacs Department of Urology, Department of Oncology, Brady Urologic Institute
Department of Urology, Department of Oncology, Brady Urologic Institute

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Introduction Over the last several decades, there have been improvements in prostate cancer diagnosis and treatment primarily due to the diagnostic/prognostic use of prostate specific antigen, the advent of nerve sparing radical prostatectomy

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-08-0205
Volume/Issue:
Volume 16: Issue 2
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Eiji Kashiwagi Departments of ce:sup loc="post">1Urology, Clinical Chemistry and Laboratory Medicine

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Masaki Shiota Departments of ce:sup loc="post">1Urology, Clinical Chemistry and Laboratory Medicine

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Akira Yokomizo Departments of ce:sup loc="post">1Urology, Clinical Chemistry and Laboratory Medicine

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Momoe Itsumi Departments of ce:sup loc="post">1Urology, Clinical Chemistry and Laboratory Medicine

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Junichi Inokuchi Departments of ce:sup loc="post">1Urology, Clinical Chemistry and Laboratory Medicine

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Takeshi Uchiumi Departments of ce:sup loc="post">1Urology, Clinical Chemistry and Laboratory Medicine

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Seiji Naito Departments of ce:sup loc="post">1Urology, Clinical Chemistry and Laboratory Medicine

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Introduction Prostate cancer is the most commonly diagnosed non-skin cancer among men in developed countries ( Jemal et al . 2008 ). In its early stages, prostate cancer cell growth is androgen dependent, and androgen deprivation therapies cause

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-12-0344
Volume/Issue:
Volume 20: Issue 3
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Muhammed H Rahaman
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Malika Kumarasiri
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Laychiluh B Mekonnen Centre for Drug Discovery and Development, Sansom Institute for Health Research and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia, Australia

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Mingfeng Yu Centre for Drug Discovery and Development, Sansom Institute for Health Research and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia, Australia

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Sarah Diab Centre for Drug Discovery and Development, Sansom Institute for Health Research and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia, Australia

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Hugo Albrecht Centre for Drug Discovery and Development, Sansom Institute for Health Research and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia, Australia

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Robert W Milne Centre for Drug Discovery and Development, Sansom Institute for Health Research and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia, Australia

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Shudong Wang Centre for Drug Discovery and Development, Sansom Institute for Health Research and School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, South Australia, Australia

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Introduction Prostate cancer (PCa) is the most common cancer diagnosed in men and is considered as one of the major causes of death in developed countries ( Siegel et al. 2015 ). It is highly prevalent in older men, with those over 65 years

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-16-0299
Volume/Issue:
Volume 23: Issue 12
Free access
Shu Feng Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA

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Irina U Agoulnik Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA

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Anne Truong Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA

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Zhen Li Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA

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Chad J Creighton Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA

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Elena M Kaftanovskaya Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA

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Rhea Pereira Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA

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Hee Dong Han Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA

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Gabriel Lopez-Berestein Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA

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Thomas Klonisch Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA

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Michael M Ittmann Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA

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Anil K Sood Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA

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Alexander I Agoulnik Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA

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Introduction Prostate cancer is the most common type of cancer in men in the United States and the second leading cause of cancer deaths. Androgens play a key role in prostate cancer initiation and progression and androgen ablation is initially

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-10-0073
Volume/Issue:
Volume 17: Issue 4
Free access
Salma Ben-Salem Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA

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Varadha Balaji Venkadakrishnan Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA

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Hannelore V Heemers Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA

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Introduction Prostate cancer (CaP) remains the second leading cause of cancer deaths in Western men ( Siegel et al. 2020 ). These deaths occur because of acquired resistance to the systemic therapies for metastatic CaP. Because of CaP

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-20-0517
Volume/Issue:
Volume 28: Issue 6
Free access
Kristina V Wells Department of Anatomy, Physiology, and Cell Biology, University of California Davis School of Veterinary Medicine, Davis, California, USA

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Margaret L Krackeler Department of Internal Medicine, University of California Davis School of Medicine, Sacramento, California, USA

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Maitreyee K Jathal Department of Medical Microbiology and Immunology, University of California Davis, Davis, California, USA
Veterans Affairs-Northern California Health System, Mather, California, USA

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Mamta Parikh Division of Hematology and Oncology, School of Medicine, University of California Davis, Sacramento, California, USA

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Paramita M Ghosh Veterans Affairs-Northern California Health System, Mather, California, USA
Department of Urologic Surgery, School of Medicine, University of California Davis, Sacramento, California, USA

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J Kent Leach Department of Orthopaedic Surgery, School of Medicine, University of California Davis, Sacramento, California, USA
Department of Biomedical Engineering, University of California Davis, Davis, California, USA

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Damian C Genetos Department of Anatomy, Physiology, and Cell Biology, University of California Davis School of Veterinary Medicine, Davis, California, USA

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Introduction Prostate cancer (PCa) is a highly prevalent health problem in the developed world. As an age-related disease that is exacerbated by Western diets and lifestyles, the global burden of PCa will only continue to rise as lifespans

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-22-0360
Volume/Issue:
Volume 30: Issue 9
Free access
Fritz H Schröder Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands

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Introduction Endocrine treatment (ET) of prostate cancer (PC) is more than 60 years old ( Huggins & Hodges 1941 , Huggins et al. 1941 ). Huggins and coworkers were awarded the Nobel Prize in 1966 for their studies in endocrine

Article Type:
Review Article
DOI:
https://doi.org/10.1677/ERC-06-0022
Volume/Issue:
Volume 14: Issue 1
Free access
Rana P Singh
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Rajesh Agarwal
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Introduction Prostate cancer (PCa) is a chronic disease, and therefore, its chemoprevention is emerging as an attractive additional strategy for disease control. In recent years, considerable progress has been made in this direction

Article Type:
Review Article
DOI:
https://doi.org/10.1677/erc.1.01126
Volume/Issue:
Volume 13: Issue 3
Free access