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Lei Quan Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA
Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Chi-Chen Hong Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Gary Zirpoli Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Michelle R Roberts Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Thaer Khoury Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Lara E Sucheston-Campbell Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Dana H Bovbjerg Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Lina Jandorf Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Karen Pawlish Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Gregory Ciupak Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Warren Davis Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Elisa V Bandera Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Christine B Ambrosone Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Song Yao Roswell Park Cancer Institute, University of Pittsburgh Cancer Institute, Icahn School of Medicine at Mount Sinai, New Jersey Department of Health, Rutgers Cancer Institute of New Jersey, Elm and Carlton Streets, Buffalo, New York 14263, USA

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Introduction Breast cancer is a heterogeneous disease. Distribution of tumor characteristics, such as the expression of estrogen receptor (ER), varies by age and ethnic/racial background ( Millikan et al . 2008 , Ambrosone et al . 2014 a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-14-0250
Volume/Issue:
Volume 21: Issue 6
Free access
Benjamin Boyerinas The Ben May Department for Cancer Research, The University of Chicago, 924 E 57th Street, Chicago, Illinois 60637, USA

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Sun-Mi Park The Ben May Department for Cancer Research, The University of Chicago, 924 E 57th Street, Chicago, Illinois 60637, USA

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Annika Hau The Ben May Department for Cancer Research, The University of Chicago, 924 E 57th Street, Chicago, Illinois 60637, USA

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Andrea E Murmann The Ben May Department for Cancer Research, The University of Chicago, 924 E 57th Street, Chicago, Illinois 60637, USA

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Marcus E Peter The Ben May Department for Cancer Research, The University of Chicago, 924 E 57th Street, Chicago, Illinois 60637, USA

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, differentiation, and apoptosis ( Jovanovic & Hengartner 2006 , Bussing et al . 2008 , Schickel et al . 2008 , Stefani & Slack 2008 ). In respect to their diverse functions, miRs are also known to be involved in many diseases including cancer

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-09-0184
Volume/Issue:
Volume 17: Issue 1
Free access
Antoinette S Perry
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Ruth Foley
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Karen Woodson
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Mark Lawler
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Introduction: addressing problems with the clinical management of prostate cancer Prostate cancer (CaP) has a unique set of problems associated with its early detection, diagnosis and treatment that might be aided by the

Article Type:
Review Article
DOI:
https://doi.org/10.1677/erc.1.01184
Volume/Issue:
Volume 13: Issue 2
Free access
Anna Angelousi Endocrine Unit, 1st Department of Internal Medicine, Laiko Hospital, National and Kapodistrian University of Athens, Athens, Greece

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Krystallenia I Alexandraki Endocrine Unit, 1st Department of Propaedeutic Medicine, Laiko University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece

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George Kyriakopoulos Department of Pathology, General Hospital ‘Evangelismos’, Αthens, Greece

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Marina Tsoli Endocrine Unit, 1st Department of Propaedeutic Medicine, Laiko University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece

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Dimitrios Thomas Endocrine Unit, 1st Department of Propaedeutic Medicine, Laiko University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece

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Gregory Kaltsas Endocrine Unit, 1st Department of Propaedeutic Medicine, Laiko University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece

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Ashley Grossman Department of Endocrinology, OCDEM, University of Oxford, Oxford, UK
Neuroendocrine Tumour Unit, Royal Free Hospital, London, UK
Centre for Endocrinology, Barts and the London School of Medicine, Queen Mary University of London, London, UK

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Introduction Cancer is a major public health issue in developed countries, with the presence of metastases being the most critical factor related to mortality ( Uemura et al . 2016 ). In this context, endocrine organ metastases usually occur

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-19-0263
Volume/Issue:
Volume 27: Issue 1
Free access
Annamaria Biroccio Experimental Chemotherapy Laboratory, Regina Elena Cancer Institute, Via delle Messi d’Oro 156, 00158 Rome, Italy

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Carlo Leonetti Experimental Chemotherapy Laboratory, Regina Elena Cancer Institute, Via delle Messi d’Oro 156, 00158 Rome, Italy

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Introduction Prostate cancer is the most frequently diagnosed malignancy, apart from skin cancers, in developed countries, and is a leading cause of cancer-related deaths in men ( Feldman & Feldman 2001 ). The risk of prostate

Article Type:
Review Article
DOI:
https://doi.org/10.1677/erc.1.00764
Volume/Issue:
Volume 11: Issue 3
Free access
Raquel Santana da Cruz Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA

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Johan Clarke Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA

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Ana Cristina P Curi Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA

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Aseel Al-Yawar Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA

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Lu Jin Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA

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Ali Baird Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA

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M Idalia Cruz Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA

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Bhaskar Kallakury Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA

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Sonia de Assis Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA

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Introduction Pancreatic ductal adenocarcinoma (PDAC) has an overall 5-year survival rate of about 9% ( American Cancer Society 2018 ). This dismal prognosis is due to lack of early detection methods, effective therapies and our poor

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-19-0016
Volume/Issue:
Volume 26: Issue 5
Free access
Marianna Volpert Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia

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Luc Furic Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia
Prostate Cancer Translational Research Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia
Cancer Program, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia

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Jinghua Hu Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia
The School of Biological Sciences, Monash University, Clayton, Victoria, Australia

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Anne E O’Connor Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia
The School of Biological Sciences, Monash University, Clayton, Victoria, Australia

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Richard J Rebello Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia

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Shivakumar Keerthikumar Prostate Cancer Translational Research Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia
Computational Cancer Biology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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Jemma Evans The Hudson Institute of Medical Research, Clayton, Victoria, Australia
Department of Physiology, Monash University, Clayton, Victoria, Australia

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D Jo Merriner Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia
The School of Biological Sciences, Monash University, Clayton, Victoria, Australia

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John Pedersen Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia

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Gail P Risbridger Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia
Prostate Cancer Translational Research Laboratory, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia
Cancer Program, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia

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Peter McIntyre Health Innovations Research Institute and School of Medical Sciences, RMIT University, Bundoora, Victoria, Australia.

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Moira K O’Bryan Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia
The School of Biological Sciences, Monash University, Clayton, Victoria, Australia

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Introduction Prostate cancer is the most common male cancer in Western societies and the third most common cause of cancer-related mortality ( Jemal et al. 2011 ). Localised prostate cancer is well managed clinically with a 5-year survival

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-20-0092
Volume/Issue:
Volume 27: Issue 7
Restricted access
Wael K Al-Delaimy Cancer Prevention and Control Program, Department of Family and Preventive Medicine, Department of Public Health Sciences, Division of Research, Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093-0628, USA
Cancer Prevention and Control Program, Department of Family and Preventive Medicine, Department of Public Health Sciences, Division of Research, Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093-0628, USA

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Shirley W Flatt Cancer Prevention and Control Program, Department of Family and Preventive Medicine, Department of Public Health Sciences, Division of Research, Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093-0628, USA

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Loki Natarajan Cancer Prevention and Control Program, Department of Family and Preventive Medicine, Department of Public Health Sciences, Division of Research, Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093-0628, USA

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Gail A Laughlin Cancer Prevention and Control Program, Department of Family and Preventive Medicine, Department of Public Health Sciences, Division of Research, Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093-0628, USA

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Cheryl L Rock Cancer Prevention and Control Program, Department of Family and Preventive Medicine, Department of Public Health Sciences, Division of Research, Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093-0628, USA

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Ellen B Gold Cancer Prevention and Control Program, Department of Family and Preventive Medicine, Department of Public Health Sciences, Division of Research, Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093-0628, USA

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Bette J Caan Cancer Prevention and Control Program, Department of Family and Preventive Medicine, Department of Public Health Sciences, Division of Research, Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093-0628, USA

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Barbara A Parker Cancer Prevention and Control Program, Department of Family and Preventive Medicine, Department of Public Health Sciences, Division of Research, Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093-0628, USA

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John P Pierce Cancer Prevention and Control Program, Department of Family and Preventive Medicine, Department of Public Health Sciences, Division of Research, Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093-0628, USA

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Introduction As a result of early screening and detection and better treatment options, the number of breast cancer survivors is increasing ( ACS 2005 ). However, there remains an ongoing risk of recurrence among a large proportion of survivors

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-10-0121
Volume/Issue:
Volume 18: Issue 2
Free access
Tanya K Day
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Tina Bianco-Miotto Dame Roma Mitchell Cancer Research Laboratories, School of Paediatrics and Reproductive Health, School of Agriculture, Discipline of Medicine, Hanson Institute, Adelaide Prostate Cancer Research Centre, The University of Adelaide, Adelaide, South Australia, Australia
Dame Roma Mitchell Cancer Research Laboratories, School of Paediatrics and Reproductive Health, School of Agriculture, Discipline of Medicine, Hanson Institute, Adelaide Prostate Cancer Research Centre, The University of Adelaide, Adelaide, South Australia, Australia

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Introduction Numerous diseases are associated with abnormal hormonal regulation including breast and prostate cancers. Breast cancer is a heterogeneous disease that can be classified in many ways. The most primary classification is by hormone

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-13-0204
Volume/Issue:
Volume 20: Issue 5
Free access
Lindsay G Carter
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John A D'Orazio Graduate Center for Nutritional Sciences, Department of Pediatrics, Markey Cancer Center, University of Kentucky College of Medicine, Wethington Building, Room 591, 900 South Limestone, Lexington, Kentucky 40536-0200, USA

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Kevin J Pearson
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been highly studied for the prevention and treatment of many diseases including cancer. After Jang et al . (1997) found that topical application of resveratrol protected mice from tumorigenesis in a skin cancer model in 1997, a wealth of publications

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-13-0171
Volume/Issue:
Volume 21: Issue 3
Open access