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Bruno Ragazzon
Bruno Ragazzon
Institut Cochin, Inserm, Department of Endocrinology, Université Paris Descartes, CNRS (UMR 8104), 75014 Paris, France
Institut Cochin, Inserm, Department of Endocrinology, Université Paris Descartes, CNRS (UMR 8104), 75014 Paris, France
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Institut Cochin, Inserm, Department of Endocrinology, Université Paris Descartes, CNRS (UMR 8104), 75014 Paris, France
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Guillaume Assié
Guillaume Assié
Institut Cochin, Inserm, Department of Endocrinology, Université Paris Descartes, CNRS (UMR 8104), 75014 Paris, France
Institut Cochin, Inserm, Department of Endocrinology, Université Paris Descartes, CNRS (UMR 8104), 75014 Paris, France
Institut Cochin, Inserm, Department of Endocrinology, Université Paris Descartes, CNRS (UMR 8104), 75014 Paris, France
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Institut Cochin, Inserm, Department of Endocrinology, Université Paris Descartes, CNRS (UMR 8104), 75014 Paris, France
Institut Cochin, Inserm, Department of Endocrinology, Université Paris Descartes, CNRS (UMR 8104), 75014 Paris, France
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Jérôme Bertherat
Jérôme Bertherat
Institut Cochin, Inserm, Department of Endocrinology, Université Paris Descartes, CNRS (UMR 8104), 75014 Paris, France
Institut Cochin, Inserm, Department of Endocrinology, Université Paris Descartes, CNRS (UMR 8104), 75014 Paris, France
Institut Cochin, Inserm, Department of Endocrinology, Université Paris Descartes, CNRS (UMR 8104), 75014 Paris, France
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Institut Cochin, Inserm, Department of Endocrinology, Université Paris Descartes, CNRS (UMR 8104), 75014 Paris, France
Institut Cochin, Inserm, Department of Endocrinology, Université Paris Descartes, CNRS (UMR 8104), 75014 Paris, France
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-catenin is localized at the cell membrane. After activation by an extracellular ligand or a genetic alteration, β-catenin is visible in the cytoplasm and/or the nucleus. In both benign and malignant ACTs, β-catenin delocalization can be observed. In the
Xinying Li
Xinying Li
Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Hunan Engineering Laboratory for Structural Biology and Drug Design
Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Hunan Engineering Laboratory for Structural Biology and Drug Design
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Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Hunan Engineering Laboratory for Structural Biology and Drug Design
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Zhiming Wang
Zhiming Wang
Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Hunan Engineering Laboratory for Structural Biology and Drug Design
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Jianming Liu
Jianming Liu
Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Hunan Engineering Laboratory for Structural Biology and Drug Design
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Cane Tang
Cane Tang
Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Hunan Engineering Laboratory for Structural Biology and Drug Design
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Chaojun Duan
Chaojun Duan
Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Hunan Engineering Laboratory for Structural Biology and Drug Design
Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Hunan Engineering Laboratory for Structural Biology and Drug Design
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Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Hunan Engineering Laboratory for Structural Biology and Drug Design
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Cui Li
Cui Li
Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Hunan Engineering Laboratory for Structural Biology and Drug Design
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aspiration (FNA) biopsy ( Baloch & LiVolsi 2007 ). Understanding the genetic alterations in FTCs and their mechanisms is fundamentally important in developing new molecular markers for earlier diagnosis and novel therapeutic targets. Kroll et al . (2000
Daphne R Pringle
Daphne R Pringle
Department of Molecular, Center for Biostatistics, National Hormone and Peptide Program, Department of Veterinary Biosciences, Division of Endocrinology, Virology, Immunology, and Medical Genetics, The Ohio State University, 420 West 12th Avenue, Tzagournis Research Facility 544, Columbus, Ohio 43210, USA
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Zhirong Yin
Zhirong Yin
Department of Molecular, Center for Biostatistics, National Hormone and Peptide Program, Department of Veterinary Biosciences, Division of Endocrinology, Virology, Immunology, and Medical Genetics, The Ohio State University, 420 West 12th Avenue, Tzagournis Research Facility 544, Columbus, Ohio 43210, USA
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Audrey A Lee
Audrey A Lee
Department of Molecular, Center for Biostatistics, National Hormone and Peptide Program, Department of Veterinary Biosciences, Division of Endocrinology, Virology, Immunology, and Medical Genetics, The Ohio State University, 420 West 12th Avenue, Tzagournis Research Facility 544, Columbus, Ohio 43210, USA
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Parmeet K Manchanda
Parmeet K Manchanda
Department of Molecular, Center for Biostatistics, National Hormone and Peptide Program, Department of Veterinary Biosciences, Division of Endocrinology, Virology, Immunology, and Medical Genetics, The Ohio State University, 420 West 12th Avenue, Tzagournis Research Facility 544, Columbus, Ohio 43210, USA
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Lianbo Yu
Lianbo Yu
Department of Molecular, Center for Biostatistics, National Hormone and Peptide Program, Department of Veterinary Biosciences, Division of Endocrinology, Virology, Immunology, and Medical Genetics, The Ohio State University, 420 West 12th Avenue, Tzagournis Research Facility 544, Columbus, Ohio 43210, USA
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Alfred F Parlow
Alfred F Parlow
Department of Molecular, Center for Biostatistics, National Hormone and Peptide Program, Department of Veterinary Biosciences, Division of Endocrinology, Virology, Immunology, and Medical Genetics, The Ohio State University, 420 West 12th Avenue, Tzagournis Research Facility 544, Columbus, Ohio 43210, USA
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David Jarjoura
David Jarjoura
Department of Molecular, Center for Biostatistics, National Hormone and Peptide Program, Department of Veterinary Biosciences, Division of Endocrinology, Virology, Immunology, and Medical Genetics, The Ohio State University, 420 West 12th Avenue, Tzagournis Research Facility 544, Columbus, Ohio 43210, USA
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Krista M D La Perle
Krista M D La Perle
Department of Molecular, Center for Biostatistics, National Hormone and Peptide Program, Department of Veterinary Biosciences, Division of Endocrinology, Virology, Immunology, and Medical Genetics, The Ohio State University, 420 West 12th Avenue, Tzagournis Research Facility 544, Columbus, Ohio 43210, USA
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Lawrence S Kirschner
Lawrence S Kirschner
Department of Molecular, Center for Biostatistics, National Hormone and Peptide Program, Department of Veterinary Biosciences, Division of Endocrinology, Virology, Immunology, and Medical Genetics, The Ohio State University, 420 West 12th Avenue, Tzagournis Research Facility 544, Columbus, Ohio 43210, USA
Department of Molecular, Center for Biostatistics, National Hormone and Peptide Program, Department of Veterinary Biosciences, Division of Endocrinology, Virology, Immunology, and Medical Genetics, The Ohio State University, 420 West 12th Avenue, Tzagournis Research Facility 544, Columbus, Ohio 43210, USA
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Department of Molecular, Center for Biostatistics, National Hormone and Peptide Program, Department of Veterinary Biosciences, Division of Endocrinology, Virology, Immunology, and Medical Genetics, The Ohio State University, 420 West 12th Avenue, Tzagournis Research Facility 544, Columbus, Ohio 43210, USA
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), which supports our hypothesis that more than one genetic alteration may be necessary to elicit metastatic thyroid cancer. The mouse expressing a transgene of the PAX8–PPARG fusion protein in the thyroid also fails to develop the FTC seen in patients
Natallia M Akulevich
Natallia M Akulevich
Departments of, Molecular Medicine, International Health and Radiation Research, Department of Thyroid Disease Research, Medical Radiological Research Center, Department of Molecular Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan
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Vladimir A Saenko
Vladimir A Saenko
Departments of, Molecular Medicine, International Health and Radiation Research, Department of Thyroid Disease Research, Medical Radiological Research Center, Department of Molecular Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan
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Tatiana I Rogounovitch
Tatiana I Rogounovitch
Departments of, Molecular Medicine, International Health and Radiation Research, Department of Thyroid Disease Research, Medical Radiological Research Center, Department of Molecular Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan
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Valentina M Drozd
Valentina M Drozd
Departments of, Molecular Medicine, International Health and Radiation Research, Department of Thyroid Disease Research, Medical Radiological Research Center, Department of Molecular Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan
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Eugeny F Lushnikov
Eugeny F Lushnikov
Departments of, Molecular Medicine, International Health and Radiation Research, Department of Thyroid Disease Research, Medical Radiological Research Center, Department of Molecular Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan
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Victor K Ivanov
Victor K Ivanov
Departments of, Molecular Medicine, International Health and Radiation Research, Department of Thyroid Disease Research, Medical Radiological Research Center, Department of Molecular Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan
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Norisato Mitsutake
Norisato Mitsutake
Departments of, Molecular Medicine, International Health and Radiation Research, Department of Thyroid Disease Research, Medical Radiological Research Center, Department of Molecular Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan
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Ryo Kominami
Ryo Kominami
Departments of, Molecular Medicine, International Health and Radiation Research, Department of Thyroid Disease Research, Medical Radiological Research Center, Department of Molecular Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan
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Shunichi Yamashita
Shunichi Yamashita
Departments of, Molecular Medicine, International Health and Radiation Research, Department of Thyroid Disease Research, Medical Radiological Research Center, Department of Molecular Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan
Departments of, Molecular Medicine, International Health and Radiation Research, Department of Thyroid Disease Research, Medical Radiological Research Center, Department of Molecular Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan
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Departments of, Molecular Medicine, International Health and Radiation Research, Department of Thyroid Disease Research, Medical Radiological Research Center, Department of Molecular Genetics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan
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/PTC occurring most frequently ( Nikiforov et al . 1997 , Rabes et al . 2000 ). While in the exposed individuals DNA damage could be attributed to IR, the origination of genetic alterations in sporadic cancers remains obscure. Nevertheless, the spectrum of
Jia-Jing Lee
Jia-Jing Lee
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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Amy Y M Au
Amy Y M Au
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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Theodoros Foukakis
Theodoros Foukakis
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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Michela Barbaro
Michela Barbaro
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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Nimrod Kiss
Nimrod Kiss
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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Roderick Clifton-Bligh
Roderick Clifton-Bligh
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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Johan Staaf
Johan Staaf
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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Åke Borg
Åke Borg
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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Leigh Delbridge
Leigh Delbridge
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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Bruce G Robinson
Bruce G Robinson
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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Göran Wallin
Göran Wallin
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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Anders Höög
Anders Höög
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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Catharina Larsson
Catharina Larsson
Department of Molecular Medicine and Surgery, Department of Oncology-Pathology, Kolling Institute of Medical Research, Department of Oncology, Karolinska Institutet, Karolinska University Hospital, CMM L8:01, SE-17176 Stockholm, Sweden
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these cases had an additional thyroid cancer; case 6 exhibited a PTC adjacent to the ATC and, in case 21, a continuous tumor spectrum from PDTC to ATC was observed. Table 2 Molecular and genetic alterations of primary anaplastic thyroid cancer (ATC
Hiroki Ueda
Hiroki Ueda
Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Yoshimitsu Akiyama
Yoshimitsu Akiyama
Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Shu Shimada
Shu Shimada
Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Kaoru Mogushi
Kaoru Mogushi
Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Misaki Serizawa
Misaki Serizawa
Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Satoshi Matsumura
Satoshi Matsumura
Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Yusuke Mitsunori
Yusuke Mitsunori
Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Arihiro Aihara
Arihiro Aihara
Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Daisuke Ban
Daisuke Ban
Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Takanori Ochiai
Takanori Ochiai
Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Atsushi Kudo
Atsushi Kudo
Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Minoru Tanabe
Minoru Tanabe
Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Shinji Tanaka
Shinji Tanaka
Department of Molecular Oncology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Department of Hepatobiliary and Pancreatic Surgery, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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and genetic alterations in human clinical samples of PanNETs. (A) Representative photographs of DAXX immunostaining in PanNET tissues. DAXX was expressed in pancreatic tissues (i). High (ii) and low (iii) expressions of DAXX were detected in PanNET
Ellinor Andersson
Ellinor Andersson
Lundberg Laboratory for Cancer Research, Lundberg Laboratory for Cancer Research, Department of Pathology
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Christina Swärd
Christina Swärd
Lundberg Laboratory for Cancer Research, Lundberg Laboratory for Cancer Research, Department of Pathology
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Göran Stenman
Göran Stenman
Lundberg Laboratory for Cancer Research, Lundberg Laboratory for Cancer Research, Department of Pathology
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Håkan Ahlman
Håkan Ahlman
Lundberg Laboratory for Cancer Research, Lundberg Laboratory for Cancer Research, Department of Pathology
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Ola Nilsson
Ola Nilsson
Lundberg Laboratory for Cancer Research, Lundberg Laboratory for Cancer Research, Department of Pathology
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disseminated midgut carcinoid tumours . British Journal of Surgery 90 687 – 693 . Kulke MH Freed E Chiang DY Philips J Zahrieh D Glickman JN Shivdasani RA 2008 High-resolution analysis of genetic alterations in small bowel carcinoid
Marianne E Pavel
Marianne E Pavel
Medical Department, Division of Hepatology and Gastroenterology including Metabolic Diseases, Campus Virchow Klinikum, Charité University Medicine, Berlin, Germany
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Christine Sers
Christine Sers
Institute of Pathology, Charité University Medicine, Berlin, Germany
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to PHLDA3 gene loss of heterozygosity ( Ohki et al . 2014 ). Table 2 Genetic alterations in neuroendocrine tumors. Study Genes (%) Type of alteration No. of patients analyzed Pancreatic neuroendocrine tumor
Thomas G Papathomas
Thomas G Papathomas
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Lindsey Oudijk
Lindsey Oudijk
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Ellen C Zwarthoff
Ellen C Zwarthoff
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Edward Post
Edward Post
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Floor A Duijkers
Floor A Duijkers
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Max M van Noesel
Max M van Noesel
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Leo J Hofland
Leo J Hofland
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Patrick J Pollard
Patrick J Pollard
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Eamonn R Maher
Eamonn R Maher
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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David F Restuccia
David F Restuccia
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Richard A Feelders
Richard A Feelders
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Gaston J H Franssen
Gaston J H Franssen
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Henri J Timmers
Henri J Timmers
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Stefan Sleijfer
Stefan Sleijfer
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Wouter W de Herder
Wouter W de Herder
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Ronald R de Krijger
Ronald R de Krijger
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Winand N M Dinjens
Winand N M Dinjens
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Esther Korpershoek
Esther Korpershoek
Department of Pathology Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands
Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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Department of Pediatric Oncology–Hematology Erasmus MC–Sophia Children's Hospital, Rotterdam, The Netherlands
Sector of Endocrinology Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
Cancer Biology and Metabolism Group Institute of Genetics and Molecular Medicine, Edinburgh Cancer Research UK Centre, University of Edinburgh, Edinburgh, UK
Department of Medical Genetics University of Cambridge, Cambridge, UK
Department of Surgery Erasmus MC, Rotterdam, The Netherlands
Division of Endocrinology Department of Medicine, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
Department of Medical Oncology Erasmus MC, Rotterdam, The Netherlands
Department of Pathology Reinier de Graaf Hospital, Delft, The Netherlands
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as well as enabling the accumulation of additional genetic alterations, and/or to other non-canonical functions interfering with extra-telomeric tumor-promoting pathways remains to be elucidated ( Greider & Blackburn 1985 , Cao et al . 2002
T Yoshimura
T Yoshimura
Department of Oral and Maxillofacial Surgery,, Geraldine Brush Cancer Research Institute,, Ehime University School of Medicine, Ehime, 791-0295, Japan
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T Sumida
T Sumida
Department of Oral and Maxillofacial Surgery,, Geraldine Brush Cancer Research Institute,, Ehime University School of Medicine, Ehime, 791-0295, Japan
Department of Oral and Maxillofacial Surgery,, Geraldine Brush Cancer Research Institute,, Ehime University School of Medicine, Ehime, 791-0295, Japan
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Department of Oral and Maxillofacial Surgery,, Geraldine Brush Cancer Research Institute,, Ehime University School of Medicine, Ehime, 791-0295, Japan
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S Liu
S Liu
Department of Oral and Maxillofacial Surgery,, Geraldine Brush Cancer Research Institute,, Ehime University School of Medicine, Ehime, 791-0295, Japan
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A Onishi
A Onishi
Department of Oral and Maxillofacial Surgery,, Geraldine Brush Cancer Research Institute,, Ehime University School of Medicine, Ehime, 791-0295, Japan
Department of Oral and Maxillofacial Surgery,, Geraldine Brush Cancer Research Institute,, Ehime University School of Medicine, Ehime, 791-0295, Japan
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Department of Oral and Maxillofacial Surgery,, Geraldine Brush Cancer Research Institute,, Ehime University School of Medicine, Ehime, 791-0295, Japan
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S Shintani
S Shintani
Department of Oral and Maxillofacial Surgery,, Geraldine Brush Cancer Research Institute,, Ehime University School of Medicine, Ehime, 791-0295, Japan
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P-Y Desprez
P-Y Desprez
Department of Oral and Maxillofacial Surgery,, Geraldine Brush Cancer Research Institute,, Ehime University School of Medicine, Ehime, 791-0295, Japan
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H Hamakawa
H Hamakawa
Department of Oral and Maxillofacial Surgery,, Geraldine Brush Cancer Research Institute,, Ehime University School of Medicine, Ehime, 791-0295, Japan
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Introduction In cancer cells, several genetic alterations are responsible for giving the cells the ability for proliferation, migration, and metastasis. These genetic alterations should be elucidated in order to understand the mechanisms of cancer
