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CNRS UMR7275, Valbonne, France
NEOGENEX CNRS International Associated Laboratory, Valbonne, France
Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
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Press. Molecular markers reveal disease mechanisms and improve patient stratification and prognostication in ACC Great progress has been made in our understanding of the pathogenesis of ACC and in the improvement of its prognostic
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index and lymph node ratio ( Cao et al . 2016 ), positron emission tomography results by means of new tracers, such as (18)F-fluorothymidine ( Johnbeck et al . 2016 ), or molecular markers, such as HOPX promoter methylation/gene expression ( Ushiku
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>15 years old, a subgroup of patients that would have a more favorable prognosis in comparison with younger patients. Future perspectives Contributions of molecular markers to the dynamic risk assessment In recent years, some studies have
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Neuroendocrine Tumour Unit, Royal Free Hospital, London, UK
Centre for Endocrinology, Barts and the London School of Medicine, Queen Mary University of London, London, UK
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’, ‘metastases’, ‘tumours’, ‘molecular markers’, ‘imaging’, ‘endocrine organ’. The above keywords were also combined with the Boolean operators AND/OR. Only English-written articles published the last 20 years (1999–2019) were included. We also excluded in vitro
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complementary use of molecular markers such as DNA hypermethylation. CaP is now the most commonly diagnosed non-cutaneous malignancy and the second leading cause of cancer-related deaths among men in the USA and Europe ( Jemal et al. 2005 a ). With ageing of
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practice in different locations. The use of molecular diagnostic tests to classify nodules to predict cancer behavior likely will evolve in the future as molecular markers are developed. For example, the data support that mutations in the promoter of
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Departments of, Clinical Biochemistry, Endocrinology and Metabolism, Pathology, Herlev Hospital, Pathology, Bispebjerg Hospital, University of Copenhagen, Pathology, ENT Head and Neck Surgery, Odense University Hospital, Bioinformatics Centre, University of Copenhagen, Department of Molecular Pathology and Tumor Pathology, Akita University Graduate School of Medicine, Danish Technical University, Informatics, Rigshospitalet
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Departments of, Clinical Biochemistry, Endocrinology and Metabolism, Pathology, Herlev Hospital, Pathology, Bispebjerg Hospital, University of Copenhagen, Pathology, ENT Head and Neck Surgery, Odense University Hospital, Bioinformatics Centre, University of Copenhagen, Department of Molecular Pathology and Tumor Pathology, Akita University Graduate School of Medicine, Danish Technical University, Informatics, Rigshospitalet
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. 2001 ). A number of studies have successfully exploited global expression profiling to identify molecular markers or signatures of thyroid neoplasia ( Barden et al . 2003 , Finley et al . 2004 , Mazzanti et al . 2004 , Lubitz et al . 2005
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stromal tumor . Hematology/Oncology Clinics of North America 23 1 – 13 , vii. ( https://doi.org/10.1016/j.hoc.2008.12.003 ) Barnett CM Corless CL Heinrich MC 2013 Gastrointestinal stromal tumors: molecular markers and genetic subtypes
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Introduction Breast cancer (BC) is the most common cancer in women ( Ghoncheh et al. 2016 ). A classification based on molecular markers and gene expression studies subdivides BC into four major subtypes, namely luminal A, luminal B, HER2
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Molecular markers of aggressiveness of thyroid cancer . Current Opinion in Endocrinology, Diabetes and Obesity 16 361 – 366 . ( doi:10.1097/MED.0b013e32832ff2cb ). Rocha GZ Dias MM Ropelle ER Osorio-Costa F Rossato FA Vercesi AE Saad MJ