Search Results

You are looking at 121 - 130 of 2,519 items for :

  • Refine by access: All content x
Clear All
Neil Sharma School of Clinical and Experimental Medicine, School of Cancer Sciences, Institute for Biomedical Research and

Search for other papers by Neil Sharma in
Google Scholar
PubMed
Close
,
Ashley Martin School of Clinical and Experimental Medicine, School of Cancer Sciences, Institute for Biomedical Research and

Search for other papers by Ashley Martin in
Google Scholar
PubMed
Close
, and
Christopher J McCabe School of Clinical and Experimental Medicine, School of Cancer Sciences, Institute for Biomedical Research and

Search for other papers by Christopher J McCabe in
Google Scholar
PubMed
Close

identifying novel therapeutic targets. It is for this reason that proteomics has become one of the most rapidly advancing fields in cancer research. Studying the expression and interactions of proteins in both normal and malignant tissues significantly

Free access
Eric Glasgow Laboratory of Cancer Genetics, Veterans Affairs Medical Center, Digestive Diseases, and GI Developmental Biology, Department of Surgery, Medicine and Lombardi Cancer Center, Georgetown University Medical Center, Medical/Dental Building, NW 213, 3900 Reservoir Road, NW, Washington, District of Columbia 20007, USA

Search for other papers by Eric Glasgow in
Google Scholar
PubMed
Close
and
Lopa Mishra Laboratory of Cancer Genetics, Veterans Affairs Medical Center, Digestive Diseases, and GI Developmental Biology, Department of Surgery, Medicine and Lombardi Cancer Center, Georgetown University Medical Center, Medical/Dental Building, NW 213, 3900 Reservoir Road, NW, Washington, District of Columbia 20007, USA
Laboratory of Cancer Genetics, Veterans Affairs Medical Center, Digestive Diseases, and GI Developmental Biology, Department of Surgery, Medicine and Lombardi Cancer Center, Georgetown University Medical Center, Medical/Dental Building, NW 213, 3900 Reservoir Road, NW, Washington, District of Columbia 20007, USA

Search for other papers by Lopa Mishra in
Google Scholar
PubMed
Close

et al . 1990 ). Mutational inactivation of TβRII represents one mechanism for the loss of TGF-β-mediated growth inhibition, which in many cases leads to the development of gastrointestinal cancer ( Arteaga et al . 1988 , 1993 , Kimchi et al . 1988

Free access
Renea A Taylor Prostate and Breast Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria 3800, Australia

Search for other papers by Renea A Taylor in
Google Scholar
PubMed
Close
,
Roxanne Toivanen Prostate and Breast Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria 3800, Australia

Search for other papers by Roxanne Toivanen in
Google Scholar
PubMed
Close
, and
Gail P Risbridger Prostate and Breast Cancer Research Group, Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria 3800, Australia

Search for other papers by Gail P Risbridger in
Google Scholar
PubMed
Close

Introduction Prostate cancer is a major cause of morbidity and mortality in men around the world, being the most common solid tumor. In America, ∼6 out of every 50 men over the age of 50 will be diagnosed with prostate cancer in his lifetime. In

Free access
L A Emens Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Oncology, The Johns Hopkins University School of Medicine, 1650 Orleans Street, Room 4M90, Baltimore, Maryland 21231-1000, USA

Search for other papers by L A Emens in
Google Scholar
PubMed
Close
,
R T Reilly Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Oncology, The Johns Hopkins University School of Medicine, 1650 Orleans Street, Room 4M90, Baltimore, Maryland 21231-1000, USA

Search for other papers by R T Reilly in
Google Scholar
PubMed
Close
, and
E M Jaffee Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Oncology, The Johns Hopkins University School of Medicine, 1650 Orleans Street, Room 4M90, Baltimore, Maryland 21231-1000, USA

Search for other papers by E M Jaffee in
Google Scholar
PubMed
Close

Introduction Improvements in the use of traditional breast cancer therapies have decreased the morbidity and mortality of breast cancer treatment, and improved the overall survival of women with early stage disease (American Cancer

Free access
Lisa Zhang Endocrine Oncology Section, Surgery Branch, National Cancer Institute, NIH, HHS, Clinical Research Center, Building 10‐CRC, Room 3‐3940, 10 Center Drive, MSC 1201, Bethesda, Maryland 20892, USA

Search for other papers by Lisa Zhang in
Google Scholar
PubMed
Close
,
Reza Rahbari Endocrine Oncology Section, Surgery Branch, National Cancer Institute, NIH, HHS, Clinical Research Center, Building 10‐CRC, Room 3‐3940, 10 Center Drive, MSC 1201, Bethesda, Maryland 20892, USA

Search for other papers by Reza Rahbari in
Google Scholar
PubMed
Close
,
Mei He Endocrine Oncology Section, Surgery Branch, National Cancer Institute, NIH, HHS, Clinical Research Center, Building 10‐CRC, Room 3‐3940, 10 Center Drive, MSC 1201, Bethesda, Maryland 20892, USA

Search for other papers by Mei He in
Google Scholar
PubMed
Close
, and
Electron Kebebew Endocrine Oncology Section, Surgery Branch, National Cancer Institute, NIH, HHS, Clinical Research Center, Building 10‐CRC, Room 3‐3940, 10 Center Drive, MSC 1201, Bethesda, Maryland 20892, USA

Search for other papers by Electron Kebebew in
Google Scholar
PubMed
Close

. 2011 ). Dietary, environmental, behavioral, and reproductive factors have been implicated in cancer gender disparity, but the molecular basis for this disparity is poorly understood. Thyroid cancer is one such cancer with a dramatically different

Free access
Elizabeth W LaPensee Department of Cancer and Cell Biology, University of Cincinnati, 3125 Eden Avenue, Cincinnati, Ohio 45267-0521, USA

Search for other papers by Elizabeth W LaPensee in
Google Scholar
PubMed
Close
and
Nira Ben-Jonathan Department of Cancer and Cell Biology, University of Cincinnati, 3125 Eden Avenue, Cincinnati, Ohio 45267-0521, USA

Search for other papers by Nira Ben-Jonathan in
Google Scholar
PubMed
Close

Introduction Each year, over a million women worldwide are diagnosed with breast cancer, accounting for 25% of all female cancers. Treatments include surgery, radiation therapy, chemotherapy, or their combinations. Neoadjuvant chemotherapy is used

Free access
K S Kimbro Department of Hematology and Oncology, Emory School of Medicine, Winship Cancer Institute, 1365 Clifton Road, NE, Atlanta, Georgia 30322, USA

Search for other papers by K S Kimbro in
Google Scholar
PubMed
Close
and
J W Simons Department of Hematology and Oncology, Emory School of Medicine, Winship Cancer Institute, 1365 Clifton Road, NE, Atlanta, Georgia 30322, USA

Search for other papers by J W Simons in
Google Scholar
PubMed
Close

Introduction Lethal clones of human cancer have the ability to adapt to hypoxic environments in primary or metastatic sites. Epigenetic and genetic mechanisms of adaptation to hypoxia, such as genetic instability, aerobic glycolysis

Free access
Dennis H Dowhan Institute for Molecular Bioscience, School of Chemistry and Molecular Biosciences, Prince Henry's Institute for Medical Research, Laboratory for Cancer Medicine, Dame Roma Mitchell Cancer Research Laboratories, University of Sydney Western Clinical School, The University of Queensland, Brisbane, Queensland 4072, Australia

Search for other papers by Dennis H Dowhan in
Google Scholar
PubMed
Close
,
Matthew J Harrison Institute for Molecular Bioscience, School of Chemistry and Molecular Biosciences, Prince Henry's Institute for Medical Research, Laboratory for Cancer Medicine, Dame Roma Mitchell Cancer Research Laboratories, University of Sydney Western Clinical School, The University of Queensland, Brisbane, Queensland 4072, Australia

Search for other papers by Matthew J Harrison in
Google Scholar
PubMed
Close
,
Natalie A Eriksson Institute for Molecular Bioscience, School of Chemistry and Molecular Biosciences, Prince Henry's Institute for Medical Research, Laboratory for Cancer Medicine, Dame Roma Mitchell Cancer Research Laboratories, University of Sydney Western Clinical School, The University of Queensland, Brisbane, Queensland 4072, Australia

Search for other papers by Natalie A Eriksson in
Google Scholar
PubMed
Close
,
Peter Bailey Institute for Molecular Bioscience, School of Chemistry and Molecular Biosciences, Prince Henry's Institute for Medical Research, Laboratory for Cancer Medicine, Dame Roma Mitchell Cancer Research Laboratories, University of Sydney Western Clinical School, The University of Queensland, Brisbane, Queensland 4072, Australia

Search for other papers by Peter Bailey in
Google Scholar
PubMed
Close
,
Michael A Pearen Institute for Molecular Bioscience, School of Chemistry and Molecular Biosciences, Prince Henry's Institute for Medical Research, Laboratory for Cancer Medicine, Dame Roma Mitchell Cancer Research Laboratories, University of Sydney Western Clinical School, The University of Queensland, Brisbane, Queensland 4072, Australia

Search for other papers by Michael A Pearen in
Google Scholar
PubMed
Close
,
Peter J Fuller Institute for Molecular Bioscience, School of Chemistry and Molecular Biosciences, Prince Henry's Institute for Medical Research, Laboratory for Cancer Medicine, Dame Roma Mitchell Cancer Research Laboratories, University of Sydney Western Clinical School, The University of Queensland, Brisbane, Queensland 4072, Australia

Search for other papers by Peter J Fuller in
Google Scholar
PubMed
Close
,
John W Funder Institute for Molecular Bioscience, School of Chemistry and Molecular Biosciences, Prince Henry's Institute for Medical Research, Laboratory for Cancer Medicine, Dame Roma Mitchell Cancer Research Laboratories, University of Sydney Western Clinical School, The University of Queensland, Brisbane, Queensland 4072, Australia

Search for other papers by John W Funder in
Google Scholar
PubMed
Close
,
Evan R Simpson Institute for Molecular Bioscience, School of Chemistry and Molecular Biosciences, Prince Henry's Institute for Medical Research, Laboratory for Cancer Medicine, Dame Roma Mitchell Cancer Research Laboratories, University of Sydney Western Clinical School, The University of Queensland, Brisbane, Queensland 4072, Australia

Search for other papers by Evan R Simpson in
Google Scholar
PubMed
Close
,
Peter J Leedman Institute for Molecular Bioscience, School of Chemistry and Molecular Biosciences, Prince Henry's Institute for Medical Research, Laboratory for Cancer Medicine, Dame Roma Mitchell Cancer Research Laboratories, University of Sydney Western Clinical School, The University of Queensland, Brisbane, Queensland 4072, Australia

Search for other papers by Peter J Leedman in
Google Scholar
PubMed
Close
,
Wayne D Tilley Institute for Molecular Bioscience, School of Chemistry and Molecular Biosciences, Prince Henry's Institute for Medical Research, Laboratory for Cancer Medicine, Dame Roma Mitchell Cancer Research Laboratories, University of Sydney Western Clinical School, The University of Queensland, Brisbane, Queensland 4072, Australia

Search for other papers by Wayne D Tilley in
Google Scholar
PubMed
Close
,
Melissa A Brown Institute for Molecular Bioscience, School of Chemistry and Molecular Biosciences, Prince Henry's Institute for Medical Research, Laboratory for Cancer Medicine, Dame Roma Mitchell Cancer Research Laboratories, University of Sydney Western Clinical School, The University of Queensland, Brisbane, Queensland 4072, Australia

Search for other papers by Melissa A Brown in
Google Scholar
PubMed
Close
,
Christine L Clarke Institute for Molecular Bioscience, School of Chemistry and Molecular Biosciences, Prince Henry's Institute for Medical Research, Laboratory for Cancer Medicine, Dame Roma Mitchell Cancer Research Laboratories, University of Sydney Western Clinical School, The University of Queensland, Brisbane, Queensland 4072, Australia

Search for other papers by Christine L Clarke in
Google Scholar
PubMed
Close
, and
George E O Muscat Institute for Molecular Bioscience, School of Chemistry and Molecular Biosciences, Prince Henry's Institute for Medical Research, Laboratory for Cancer Medicine, Dame Roma Mitchell Cancer Research Laboratories, University of Sydney Western Clinical School, The University of Queensland, Brisbane, Queensland 4072, Australia

Search for other papers by George E O Muscat in
Google Scholar
PubMed
Close

, their aberrant expression and activity have been linked to a number of human diseases, including cancer ( Aletta & Hu 2008 ). PRMTs regulate transcription by functioning as co-activators for a range of transcription factors, including steroid

Free access
Marie Colombe Agahozo Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

Search for other papers by Marie Colombe Agahozo in
Google Scholar
PubMed
Close
,
Anieta M Sieuwerts Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

Search for other papers by Anieta M Sieuwerts in
Google Scholar
PubMed
Close
,
S Charlane Doebar Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

Search for other papers by S Charlane Doebar in
Google Scholar
PubMed
Close
,
Esther I Verhoef Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

Search for other papers by Esther I Verhoef in
Google Scholar
PubMed
Close
,
Corine M Beaufort Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

Search for other papers by Corine M Beaufort in
Google Scholar
PubMed
Close
,
Kirsten Ruigrok-Ritstier Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

Search for other papers by Kirsten Ruigrok-Ritstier in
Google Scholar
PubMed
Close
,
Vanja de Weerd Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

Search for other papers by Vanja de Weerd in
Google Scholar
PubMed
Close
,
Hein F B M Sleddens Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

Search for other papers by Hein F B M Sleddens in
Google Scholar
PubMed
Close
,
Winand N M Dinjens Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

Search for other papers by Winand N M Dinjens in
Google Scholar
PubMed
Close
,
John W M Martens Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

Search for other papers by John W M Martens in
Google Scholar
PubMed
Close
, and
Carolien H M van Deurzen Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands

Search for other papers by Carolien H M van Deurzen in
Google Scholar
PubMed
Close

Introduction Invasive breast cancer (IBC) is a heterogeneous disease, consisting of several molecular subtypes, all with a specific tumor biology and clinical outcome ( Perou et al. 2000 ). Each of these molecular subtypes, which are based

Free access
Kevin C Knower Cancer Drug Discovery, Department of Molecular Biology and Biochemistry, Department of Environmental Health, MIMR-PHI Institute of Medical Research, PO BOX 5152, Clayton, Victoria 3168, Australia

Search for other papers by Kevin C Knower in
Google Scholar
PubMed
Close
,
Sarah Q To Cancer Drug Discovery, Department of Molecular Biology and Biochemistry, Department of Environmental Health, MIMR-PHI Institute of Medical Research, PO BOX 5152, Clayton, Victoria 3168, Australia
Cancer Drug Discovery, Department of Molecular Biology and Biochemistry, Department of Environmental Health, MIMR-PHI Institute of Medical Research, PO BOX 5152, Clayton, Victoria 3168, Australia

Search for other papers by Sarah Q To in
Google Scholar
PubMed
Close
,
Yuet-Kin Leung Cancer Drug Discovery, Department of Molecular Biology and Biochemistry, Department of Environmental Health, MIMR-PHI Institute of Medical Research, PO BOX 5152, Clayton, Victoria 3168, Australia

Search for other papers by Yuet-Kin Leung in
Google Scholar
PubMed
Close
,
Shuk-Mei Ho Cancer Drug Discovery, Department of Molecular Biology and Biochemistry, Department of Environmental Health, MIMR-PHI Institute of Medical Research, PO BOX 5152, Clayton, Victoria 3168, Australia

Search for other papers by Shuk-Mei Ho in
Google Scholar
PubMed
Close
, and
Colin D Clyne Cancer Drug Discovery, Department of Molecular Biology and Biochemistry, Department of Environmental Health, MIMR-PHI Institute of Medical Research, PO BOX 5152, Clayton, Victoria 3168, Australia
Cancer Drug Discovery, Department of Molecular Biology and Biochemistry, Department of Environmental Health, MIMR-PHI Institute of Medical Research, PO BOX 5152, Clayton, Victoria 3168, Australia

Search for other papers by Colin D Clyne in
Google Scholar
PubMed
Close

Introduction Normal growth and function of the mammary glands are dependent on the body's endocrine system. Many factors that influence breast cancer risk are therefore endocrine-associated processes, such as age at menopause, age at menarche

Free access