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Adriana Albani, Luis Gustavo Perez-Rivas, Sicheng Tang, Julia Simon, Kristin Elisabeth Lucia, Paula Colón-Bolea, Jochen Schopohl, Sigrun Roeber, Michael Buchfelder, Roman Rotermund, Jörg Flitsch, Jun Thorsteinsdottir, Jochen Herms, Günter Stalla, Martin Reincke, and Marily Theodoropoulou

bilateral adrenalectomy ( Ritzel et al. 2013 , Pivonello et al. 2015 , Tritos & Biller 2018 , Feelders et al. 2019 ). The somatostatin analogue pasireotide is the only pituitary-targeting pharmaceutical that is approved for the treatment of

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Adrian F Daly, Emilie Castermans, Lindsey Oudijk, Mirtha A Guitelman, Pablo Beckers, Iulia Potorac, Sebastian J C M M Neggers, Nathalie Sacre, Aart-Jan van der Lely, Vincent Bours, Wouter W de Herder, and Albert Beckers

), which were confirmed histologically following bilateral adrenalectomy. Further investigation for other tumor sites revealed a single thyroid nodule (9 mm). Calcitonin levels were normal. The thyroid lesion was determined to be a follicular variant of

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Jacques Amar, Jeremy Brunel, Catherine Cardot Bauters, Virginie Jacques, Clément Delmas, Marie-Françoise Odou, and Frédérique Savagner

performed ( Lenders et al. 2014 ) or in patients at high surgical risk. Indeed, as a consequence of bilateral adrenalectomy, patients became steroid dependent and will develop in 30% of cases either adrenal crisis or symptoms consistent with steroid over

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Tobias Krauss, Alfonso Massimiliano Ferrara, Thera P Links, Ulrich Wellner, Irina Bancos, Andrey Kvachenyuk, Karina Villar Gómez de las Heras, Marina Y Yukina, Roman Petrov, Garrett Bullivant, Laura von Duecker, Swati Jadhav, Ursula Ploeckinger, Staffan Welin, Camilla Schalin-Jäntti, Oliver Gimm, Marija Pfeifer, Joanne Ngeow, Kornelia Hasse-Lazar, Gabriela Sansó, Xiaoping Qi, M Umit Ugurlu, Rene E Diaz, Nelson Wohllk, Mariola Peczkowska, Jens Aberle, Delmar M Lourenço Jr, Maria A A Pereira, Maria C B V Fragoso, Ana O Hoff, Madson Q Almeida, Alice H D Violante, Ana R P Quidute, Zhewei Zhang, Mònica Recasens, Luis Robles Díaz, Tada Kunavisarut, Taweesak Wannachalee, Sirinart Sirinvaravong, Eric Jonasch, Simona Grozinsky-Glasberg, Merav Fraenkel, Dmitry Beltsevich, Viacheslav I Egorov, Dirk Bausch, Matthias Schott, Nikolaus Tiling, Gianmaria Pennelli, Stefan Zschiedrich, Roland Därr, Juri Ruf, Timm Denecke, Karl-Heinrich Link, Stefania Zovato, Ernst von Dobschuetz, Svetlana Yaremchuk, Holger Amthauer, Özer Makay, Attila Patocs, Martin K Walz, Tobias B Huber, Jochen Seufert, Per Hellman, Raymond H Kim, Ekaterina Kuchinskaya, Francesca Schiavi, Angelica Malinoc, Nicole Reisch, Barbara Jarzab, Marta Barontini, Andrzej Januszewicz, Nalini Shah, William F Young Jr, Giuseppe Opocher, Charis Eng, Hartmut P H Neumann, and Birke Bausch

. Blindness occurred bilaterally in 2 and unilaterally in 19 patients. Steroid dependency after bilateral adrenalectomy for pheochromocytoma occurred in 26, severe neurological deficits after removal of CNS hemangioblastomas in 24 patients, respectively

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Samuel A Wells Jr

unilateral adrenalectomy ( Lairmore et al . 1993 , Asari et al . 2006 ). Following a bilateral adrenalectomy, patients are at risk for an Addisonian crisis, especially if they become injured, or ill, or receive inadequate glucocorticoid replacement

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Jean-Pierre Bayley, Marjan M Weiss, Anneliese Grimbergen, Bernadette T J van Brussel, Frederik J Hes, Jeroen C Jansen, Senno Verhoef, Peter Devilee, Eleonora P Corssmit, and Annette H J T Vriends

showed an increased uptake of 123 I-MIBG, suggesting a bilateral pheochromocytoma. Bilateral adrenalectomy was performed and histological examination confirmed the diagnosis of bilateral pheochromocytoma. A few months after this surgery, a resection of

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Alberto Fernandez, Michael Brada, Lina Zabuliene, Niki Karavitaki, and John A H Wass

22.5 Gy 79 Patients 51% Surgery 2.3 years 0% Hypopituitarism 23 NFA 29 Acro 15 PRL 12 CD Höybye et al . (2001) GKRS, maximum dose 60–240 Gy 18 Patients with CD 5% Bilateral adrenalectomy 16.8 years 100% GHD 33% GT 10% Surgery 50% ACTH 55% GKRS 56

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Riccardo Ponzone, Paola Mininanni, Elisa Cassina, Francesca Pastorino, and Piero Sismondi

TL Huggins C 1955 Bilateral adrenalectomy in the treatment of cancer of the breast . Archives of Surgery 71 645 – 657 . Dowsett M Cuzick J Wale C Howell T Houghton J Baum M 2005 Retrospective analysis of time to recurrence in the ATAC

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Patricia de Cremoux, Dan Rosenberg, Jacques Goussard, Catherine Brémont-Weil, Frédérique Tissier, Carine Tran-Perennou, Lionnel Groussin, Xavier Bertagna, Jérôme Bertherat, and Marie-Laure Raffin-Sanson

was observed. Abdominal CT scan showed adrenal glands of normal size. Bilateral adrenalectomy was performed a few weeks later, and histological features confirmed the diagnosis of PPNAD. The sporadic adrenocortical tumors studied consisted of 15 ACAs

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Ben C Whitelaw

therapies. Temozolomide was used as monotherapy and then in combination with cabecitabine; however, there was progression of the primary tumour and liver metastases. Cushing’s was controlled with bilateral adrenalectomy. The patient was then treated with two