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Matthias Beyens
Matthias Beyens
Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium
Center for Oncological Research, University of Antwerp, Antwerp, Belgium
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Center for Oncological Research, University of Antwerp, Antwerp, Belgium
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Timon Vandamme
Timon Vandamme
Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium
Center for Oncological Research, University of Antwerp, Antwerp, Belgium
Section of Endocrinology, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands
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Center for Oncological Research, University of Antwerp, Antwerp, Belgium
Section of Endocrinology, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands
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Marc Peeters
Marc Peeters
Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium
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Guy Van Camp
Guy Van Camp
Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium
Center for Oncological Research, University of Antwerp, Antwerp, Belgium
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Center for Oncological Research, University of Antwerp, Antwerp, Belgium
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Ken Op de Beeck
Ken Op de Beeck
Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium
Center for Oncological Research, University of Antwerp, Antwerp, Belgium
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Center for Oncological Research, University of Antwerp, Antwerp, Belgium
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regulating cell growth, proliferation, survival and protein synthesis in gastroenteropancreatic neuroendocrine tumors (GEP-NETs) ( Missiaglia et al. 2010 , Jiao et al. 2011 , Kasajima et al. 2011 ). GEP-NETs include small intestinal NETs (siNETs) and
Ulrich-Frank Pape
Ulrich-Frank Pape
Department of Hepatology and Gastroenterology, Institute for Social Medicine, Institute for Pathology, Department of Gastroenterology, Charité, Campus Virchow Klinikum
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Uta Berndt
Uta Berndt
Department of Hepatology and Gastroenterology, Institute for Social Medicine, Institute for Pathology, Department of Gastroenterology, Charité, Campus Virchow Klinikum
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Jacqueline Müller-Nordhorn
Jacqueline Müller-Nordhorn
Department of Hepatology and Gastroenterology, Institute for Social Medicine, Institute for Pathology, Department of Gastroenterology, Charité, Campus Virchow Klinikum
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Michael Böhmig
Michael Böhmig
Department of Hepatology and Gastroenterology, Institute for Social Medicine, Institute for Pathology, Department of Gastroenterology, Charité, Campus Virchow Klinikum
Department of Hepatology and Gastroenterology, Institute for Social Medicine, Institute for Pathology, Department of Gastroenterology, Charité, Campus Virchow Klinikum
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Department of Hepatology and Gastroenterology, Institute for Social Medicine, Institute for Pathology, Department of Gastroenterology, Charité, Campus Virchow Klinikum
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Stephanie Roll
Stephanie Roll
Department of Hepatology and Gastroenterology, Institute for Social Medicine, Institute for Pathology, Department of Gastroenterology, Charité, Campus Virchow Klinikum
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Martin Koch
Martin Koch
Department of Hepatology and Gastroenterology, Institute for Social Medicine, Institute for Pathology, Department of Gastroenterology, Charité, Campus Virchow Klinikum
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Stefan N Willich
Stefan N Willich
Department of Hepatology and Gastroenterology, Institute for Social Medicine, Institute for Pathology, Department of Gastroenterology, Charité, Campus Virchow Klinikum
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Bertram Wiedenmann
Bertram Wiedenmann
Department of Hepatology and Gastroenterology, Institute for Social Medicine, Institute for Pathology, Department of Gastroenterology, Charité, Campus Virchow Klinikum
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. 2004 ). According to the largest series of NET studied to date ( Modlin et al . 2003 ), the majority of NET arise within the gastroenteropancreatic system (GEP) while the bronchial tract represents the second most frequent primary tumour localization
Dik J Kwekkeboom
Dik J Kwekkeboom
Departments of, Nuclear Medicine, Surgery, Internal Medicine
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Boen L Kam
Boen L Kam
Departments of, Nuclear Medicine, Surgery, Internal Medicine
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Martijn van Essen
Martijn van Essen
Departments of, Nuclear Medicine, Surgery, Internal Medicine
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Jaap J M Teunissen
Jaap J M Teunissen
Departments of, Nuclear Medicine, Surgery, Internal Medicine
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Casper H J van Eijck
Casper H J van Eijck
Departments of, Nuclear Medicine, Surgery, Internal Medicine
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Roelf Valkema
Roelf Valkema
Departments of, Nuclear Medicine, Surgery, Internal Medicine
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Marion de Jong
Marion de Jong
Departments of, Nuclear Medicine, Surgery, Internal Medicine
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Wouter W de Herder
Wouter W de Herder
Departments of, Nuclear Medicine, Surgery, Internal Medicine
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Eric P Krenning
Eric P Krenning
Departments of, Nuclear Medicine, Surgery, Internal Medicine
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) Astrocytoma ( Schmidt et al . 1998 ) High sensitivity, detection rate >75%; intermediate sensitivity, detection rate 40–75%. Sensitivity is either patient or lesion based. GEPNET, gastroenteropancreatic neuroendocrine tumor; NHL, non-Hodgkin lymphoma
A Mohamed
A Mohamed
Division of Hematology and Medical Oncology, UH Seidman Cancer Center, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, USA
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M Trybula
M Trybula
Division of Hematology and Medical Oncology, UH Seidman Cancer Center, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, USA
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S L Asa
S L Asa
Department of Medicine, UH Seidman Cancer Center Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, USA
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T R Halfdanarson
T R Halfdanarson
Division of Medical Oncology, Department of Oncology, Mayo Clinic Comprehensive Cancer Center, Rochester, Minnesota, USA
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M B Sonbol
M B Sonbol
Division of Hematology and Medical Oncology, Mayo Clinic Cancer Center, Phoenix, Arizona, USA
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Introduction Although rare, gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) have seen a significant increase in annual incidence over recent decades ( Fraenkel et al. 2014 , Dasari et al. 2017 , Das & Dasari 2021 , White et
Wiebke Werner
Wiebke Werner
Department of Hepatology and Gastroenterology, Charité Universitaetsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany
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Katharina Detjen
Katharina Detjen
Department of Hepatology and Gastroenterology, Charité Universitaetsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany
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Alix Bruneau
Alix Bruneau
Department of Hepatology and Gastroenterology, Charité Universitaetsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany
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Isabella Lurje
Isabella Lurje
Department of Hepatology and Gastroenterology, Charité Universitaetsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany
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Natalie Nestel
Natalie Nestel
Department of Hepatology and Gastroenterology, Charité Universitaetsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany
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Henning Jann
Henning Jann
Department of Hepatology and Gastroenterology, Charité Universitaetsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany
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Frank Tacke
Frank Tacke
Department of Hepatology and Gastroenterology, Charité Universitaetsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany
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Bertram Wiedenmann
Bertram Wiedenmann
Department of Hepatology and Gastroenterology, Charité Universitaetsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany
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Christoph Roderburg
Christoph Roderburg
Department of Hepatology and Gastroenterology, Charité Universitaetsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany
Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine, University Düsseldorf, Düsseldorf, Germany
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Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine, University Düsseldorf, Düsseldorf, Germany
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Linda Hammerich
Linda Hammerich
Department of Hepatology and Gastroenterology, Charité Universitaetsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany
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Introduction Gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) account for approximately two-thirds of all neuroendocrine malignancies ( Kaliszewski et al. 2022 ). The current World Health Organization (WHO) classification system
Esben Andreas Carlsen
Esben Andreas Carlsen
Department of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet, Copenhagen, Denmark
Department of Biomedical Sciences, Cluster for Molecular Imaging, University of Copenhagen, Copenhagen, Denmark
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Department of Biomedical Sciences, Cluster for Molecular Imaging, University of Copenhagen, Copenhagen, Denmark
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Nicola Fazio
Nicola Fazio
Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, IEO, European Institute of Oncology IRCCS, Milan, Italy
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Dan Granberg
Dan Granberg
Department of Medical Sciences, Uppsala University, Uppsala, Sweden
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Simona Grozinsky-Glasberg
Simona Grozinsky-Glasberg
Neuroendocrine Tumor Unit, Department of Endocrinology & Metabolism, Hadassah-Hebrew University Medical Center, Jerusalem, Israel
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Hojjat Ahmadzadehfar
Hojjat Ahmadzadehfar
Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany
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Chiara Maria Grana
Chiara Maria Grana
Division of Nuclear Medicine, IEO, European Institute of Oncology IRCCS, Milan, Italy
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Wouter T Zandee
Wouter T Zandee
Erasmus Medical Center, Rotterdam, The Netherlands
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Jaroslaw Cwikla
Jaroslaw Cwikla
Medical School, University of Warmia and Mazury, Olsztyn, Poland
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Martin A Walter
Martin A Walter
Department of Nuclear Medicine, University Hospital of Geneva, Geneva, Switzerland
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Peter Sandor Oturai
Peter Sandor Oturai
Department of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet, Copenhagen, Denmark
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Anja Rinke
Anja Rinke
Department of Gastroenterology, University Hospital Gießen and Marburg, Marburg, Germany
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Andrew Weaver
Andrew Weaver
Department of Oncology, Churchill Hospital, Oxford, UK
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Andrea Frilling
Andrea Frilling
Department of Surgery and Cancer, Imperial College London, London, UK
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Sara Gritti
Sara Gritti
Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, IEO, European Institute of Oncology IRCCS, Milan, Italy
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Anne Kirstine Arveschoug
Anne Kirstine Arveschoug
Department of Nuclear Medicine and PET, Aarhus University Hospital, Aarhus, Denmark
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Amichay Meirovitz
Amichay Meirovitz
Department of Oncology and Radiation Therapy Unit, Hadassah-Hebrew University Medical Center, Jerusalem, Israel
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Ulrich Knigge
Ulrich Knigge
Department of Biomedical Sciences, Cluster for Molecular Imaging, University of Copenhagen, Copenhagen, Denmark
Departments of Surgical Gastroenterology and Clinical Endocrinology, Rigshospitalet, Copenhagen, Denmark
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Departments of Surgical Gastroenterology and Clinical Endocrinology, Rigshospitalet, Copenhagen, Denmark
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Halfdan Sorbye
Halfdan Sorbye
Department of Oncology, Haukeland University Hospital, Bergen, Norway
Department of Clinical Science, University of Bergen, Bergen, Norway
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Department of Clinical Science, University of Bergen, Bergen, Norway
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poorly differentiated high-grade neuroendocrine carcinomas (G3). The terminology of NEN G3 relates to all high-grade (G3, Ki-67 >20%) neuroendocrine malignancies; i.e. both NET G3 and NEC. Gastroenteropancreatic (GEP) NENs G3 are rare, highly malignant
M Fraenkel
M Fraenkel
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M Kim
M Kim
Endocrinology, Mount Sinai Medical Center, Department of Clinical Medicine and Surgery, Endocrinology, Erasmus MC, Department of Internal Medicine, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheeba, Israel
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A Faggiano
A Faggiano
Endocrinology, Mount Sinai Medical Center, Department of Clinical Medicine and Surgery, Endocrinology, Erasmus MC, Department of Internal Medicine, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheeba, Israel
Endocrinology, Mount Sinai Medical Center, Department of Clinical Medicine and Surgery, Endocrinology, Erasmus MC, Department of Internal Medicine, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheeba, Israel
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Endocrinology, Mount Sinai Medical Center, Department of Clinical Medicine and Surgery, Endocrinology, Erasmus MC, Department of Internal Medicine, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheeba, Israel
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W W de Herder
W W de Herder
Endocrinology, Mount Sinai Medical Center, Department of Clinical Medicine and Surgery, Endocrinology, Erasmus MC, Department of Internal Medicine, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheeba, Israel
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G D Valk
G D Valk
Endocrinology, Mount Sinai Medical Center, Department of Clinical Medicine and Surgery, Endocrinology, Erasmus MC, Department of Internal Medicine, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheeba, Israel
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On behalf of the Knowledge NETwork
On behalf of the Knowledge NETwork
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studies being published, we still lack adequate epidemiological information on NETs. This lack of data only partially explains the strong discrepancy between the estimated incidence of gastroenteropancreatic (GEP)-NETs and the higher frequency of these
Andreas Venizelos
Andreas Venizelos
K.G. Jebsen Center for Genome-Directed Cancer Therapy, Department of Clinical Science, University of Bergen, Bergen, Norway
Department of Oncology, Haukeland University Hospital, Bergen, Norway
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Department of Oncology, Haukeland University Hospital, Bergen, Norway
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Halfdan Sorbye
Halfdan Sorbye
Department of Oncology, Haukeland University Hospital, Bergen, Norway
Department of Clinical Science, University of Bergen, Bergen, Norway
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Department of Clinical Science, University of Bergen, Bergen, Norway
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Hege Elvebakken
Hege Elvebakken
Department of Oncology, Ålesund Hospital, Møre og Romsdal Hospital Trust, Ålesund, Norway
Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
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Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
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Aurel Perren
Aurel Perren
Institute of Tissue Medicine and Pathology, University of Bern, Bern, Switzerland
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Inger Marie B Lothe
Inger Marie B Lothe
Department of Pathology, Oslo University Hospital, Oslo, Norway
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Anne Couvelard
Anne Couvelard
Department of Pathology, Université Paris Cité and AP-HP, Bichat Hospital, Paris, France
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Geir Olav Hjortland
Geir Olav Hjortland
Department of Oncology, Oslo University Hospital, Oslo, Norway
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Anna Sundlöv
Anna Sundlöv
Departmentt of Oncology, Skåne University Hospital, Lund, Sweden
Department of Medical Radiation Physics, Lund University, Lund, Sweden
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Department of Medical Radiation Physics, Lund University, Lund, Sweden
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Johanna Svensson
Johanna Svensson
Department of Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Harrish Garresori
Harrish Garresori
Department of Oncology, Stavanger University Hospital, Stavanger, Norway
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Christian Kersten
Christian Kersten
Department of Research, Hospital of Southern Norway, Kristiansand, Norway
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Eva Hofsli
Eva Hofsli
Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
Department of Oncology, St. Olavs Hospital, Trondheim, Norway
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Department of Oncology, St. Olavs Hospital, Trondheim, Norway
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Sönke Detlefsen
Sönke Detlefsen
Department of Pathology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark
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Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark
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Lene W Vestermark
Lene W Vestermark
Department of Oncology, Odense University Hospital, Odense, Denmark
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Morten Ladekarl
Morten Ladekarl
Department of Oncology, Aarhus University Hospital, Aarhus, Denmark
Department of Oncology, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark
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Department of Oncology, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark
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Elizaveta Mitkina Tabaksblat
Elizaveta Mitkina Tabaksblat
Department of Oncology, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark
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Stian Knappskog
Stian Knappskog
K.G. Jebsen Center for Genome-Directed Cancer Therapy, Department of Clinical Science, University of Bergen, Bergen, Norway
Department of Oncology, Haukeland University Hospital, Bergen, Norway
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Department of Oncology, Haukeland University Hospital, Bergen, Norway
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Introduction Neuroendocrine neoplasms (NENs) constitute ~2% of all malignancies and are frequently located in the gastrointestinal (GI) tract and pancreas. High-grade gastroenteropancreatic (HG-GEP) NENs are among the most aggressive cancers
Cosimo Durante
Cosimo Durante
Service de Médecine Nucléaire et de Cancérologie Endocrinienne, INSERM u605, Département de Radiologie, Département d'Anatomo-Pathologie, Département de Chirurgie, Département de Médecine, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
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Houda Boukheris
Houda Boukheris
Service de Médecine Nucléaire et de Cancérologie Endocrinienne, INSERM u605, Département de Radiologie, Département d'Anatomo-Pathologie, Département de Chirurgie, Département de Médecine, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
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Clarisse Dromain
Clarisse Dromain
Service de Médecine Nucléaire et de Cancérologie Endocrinienne, INSERM u605, Département de Radiologie, Département d'Anatomo-Pathologie, Département de Chirurgie, Département de Médecine, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
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Pierre Duvillard
Pierre Duvillard
Service de Médecine Nucléaire et de Cancérologie Endocrinienne, INSERM u605, Département de Radiologie, Département d'Anatomo-Pathologie, Département de Chirurgie, Département de Médecine, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
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Sophie Leboulleux
Sophie Leboulleux
Service de Médecine Nucléaire et de Cancérologie Endocrinienne, INSERM u605, Département de Radiologie, Département d'Anatomo-Pathologie, Département de Chirurgie, Département de Médecine, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
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Dominique Elias
Dominique Elias
Service de Médecine Nucléaire et de Cancérologie Endocrinienne, INSERM u605, Département de Radiologie, Département d'Anatomo-Pathologie, Département de Chirurgie, Département de Médecine, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
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Thierry de Baere
Thierry de Baere
Service de Médecine Nucléaire et de Cancérologie Endocrinienne, INSERM u605, Département de Radiologie, Département d'Anatomo-Pathologie, Département de Chirurgie, Département de Médecine, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
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David Malka
David Malka
Service de Médecine Nucléaire et de Cancérologie Endocrinienne, INSERM u605, Département de Radiologie, Département d'Anatomo-Pathologie, Département de Chirurgie, Département de Médecine, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
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Jean Lumbroso
Jean Lumbroso
Service de Médecine Nucléaire et de Cancérologie Endocrinienne, INSERM u605, Département de Radiologie, Département d'Anatomo-Pathologie, Département de Chirurgie, Département de Médecine, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
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Joël Guigay
Joël Guigay
Service de Médecine Nucléaire et de Cancérologie Endocrinienne, INSERM u605, Département de Radiologie, Département d'Anatomo-Pathologie, Département de Chirurgie, Département de Médecine, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
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Martin Schlumberger
Martin Schlumberger
Service de Médecine Nucléaire et de Cancérologie Endocrinienne, INSERM u605, Département de Radiologie, Département d'Anatomo-Pathologie, Département de Chirurgie, Département de Médecine, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
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Michel Ducreux
Michel Ducreux
Service de Médecine Nucléaire et de Cancérologie Endocrinienne, INSERM u605, Département de Radiologie, Département d'Anatomo-Pathologie, Département de Chirurgie, Département de Médecine, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
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Eric Baudin
Eric Baudin
Service de Médecine Nucléaire et de Cancérologie Endocrinienne, INSERM u605, Département de Radiologie, Département d'Anatomo-Pathologie, Département de Chirurgie, Département de Médecine, Institut Gustave-Roussy, Université Paris XI, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
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Introduction Gastroenteropancreatic neuroendocrine tumors (GEP NET), recently renamed endocrine tumors, are a group of tumors defined by the expression of a set of structural proteins and hormonal products common to neurons and endocrine cells
M Heetfeld
M Heetfeld
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C N Chougnet
C N Chougnet
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
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I H Olsen
I H Olsen
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
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A Rinke
A Rinke
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
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I Borbath
I Borbath
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
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G Crespo
G Crespo
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
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J Barriuso
J Barriuso
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
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M Pavel
M Pavel
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D O'Toole
D O'Toole
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
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T Walter
T Walter
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
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other Knowledge Network members
other Knowledge Network members
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Introduction Gastroenteropancreatic neuroendocrine neoplasms (GEP-NEN) are rare tumors defined by the presence of specific biomarkers ( Yao et al . 2008 ). The differentiation status is a major prognostic factor, regardless of primary site and
