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Philippe L Bedard
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Sandeep K Singhal Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada

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Michail Ignatiadis Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada

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Ian Bradbury Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada

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Benjamin Haibe-Kains Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada
Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada

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Christine Desmedt Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada

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Sherene Loi Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada

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Dean B Evans Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada

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Stefan Michiels Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada

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J Michael Dixon Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada

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William R Miller Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada

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Martine J Piccart Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada

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Christos Sotiriou Division of Medical Oncology and Hematology, Breast Cancer Translational Research Laboratory JC Heuson, Frontier Science (Scotland) Ltd, School of Medicine, Machine Learning Group, Novartis Institutes for BioMedical Research, Breakthrough Breast Research Group, University of Edinburgh, Department of Biostatistics and Computational Biology, Department of Medicine, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada

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genomic grade and high genomic grade tumors, with long-term outcomes that resemble low and high histological grade tumors in the absence of systemic therapy ( Sotiriou et al . 2006 ). At least, four distinct clinically relevant molecular subtypes of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-11-0180
Volume/Issue:
Volume 18: Issue 6
Free access
Florian Bösch Department of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Munich, Munich, Germany
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, Ludwig-Maximilians-University of Munich, Munich, Germany

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Katharina Brüwer Department of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Munich, Munich, Germany
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, Ludwig-Maximilians-University of Munich, Munich, Germany

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Annelore Altendorf-Hofmann Department of General, Visceral und Vascular Surgery, Friedrich-Schiller University, Jena, Germany

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Christoph J Auernhammer Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, Ludwig-Maximilians-University Munich, Munich, Germany

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Christine Spitzweg Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, Ludwig-Maximilians-University Munich, Munich, Germany

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C Benedikt Westphalen Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Medicine 3 and Comprehensive Cancer Center, Ludwig-Maximilians-University Munich, Munich, Germany

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Stefan Boeck Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Medicine 3 and Comprehensive Cancer Center, Ludwig-Maximilians-University Munich, Munich, Germany

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Gabriele Schubert-Fritschle Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, Ludwig-Maximilians-University of Munich, Munich, Germany
Munich Cancer Registry (MCR) of the Munich Tumour Centre (TZM), Institute for Medical Information Processing, Biometry, and Epidemiology (IBE), Ludwig-Maximilians-University Munich, Munich, Germany

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Jens Werner Department of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Munich, Munich, Germany
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, Ludwig-Maximilians-University of Munich, Munich, Germany

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Volker Heinemann Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Medicine 3 and Comprehensive Cancer Center, Ludwig-Maximilians-University Munich, Munich, Germany

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Thomas Kirchner Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, Ludwig-Maximilians-University of Munich, Munich, Germany
Institute of Pathology, Ludwig-Maximilians-University, Munich, Germany

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Martin Angele Department of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Munich, Munich, Germany
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, Ludwig-Maximilians-University of Munich, Munich, Germany

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Thomas Knösel Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, Ludwig-Maximilians-University of Munich, Munich, Germany
Institute of Pathology, Ludwig-Maximilians-University, Munich, Germany

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1.6 Correlation between TILs, PD-1 and PD-L1 expression and grading High TILs (≥3 lymphocytes per TMA-spot) could be evaluated in 47 cases (19.6%). High PD-1 expression in TILs was seen in 35 samples (16.1%), and 20 samples (8

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-18-0494
Volume/Issue:
Volume 26: Issue 3
Free access
Cindy H Chau Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA

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Cathee Till SWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

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Douglas K Price Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA

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Phyllis J Goodman SWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

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Marian L Neuhouser Cancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

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Michael N Pollak Department of Oncology and Medicine, McGill University, Montreal, Canada

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Ian M Thompson CHRISTUS Santa Rosa Hospital Medical Center, San Antonio, Texas, USA

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William D Figg Genitourinary Malignancies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA

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data from the Prostate Cancer Prevention Trial (PCPT), we previously found obesity is associated with an increased risk of high-grade prostate cancer and a decreased risk of low-grade disease ( Gong et al. 2006 ). In the current follow-up study, we

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-21-0107
Volume/Issue:
Volume 29: Issue 2
Restricted access
Tania Moujaber Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, New South Wales, Australia
Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, Western Sydney Local Health District, New South Wales, Australia
Blacktown Cancer and Haematology Centre, Blacktown Hospital, Western Sydney Local Health District, New South Wales, Australia

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Rosemary L Balleine Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, New South Wales, Australia
Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia
Children’s Medical Research Institute, Sydney, New South Wales, Australia

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Bo Gao Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, Western Sydney Local Health District, New South Wales, Australia
Blacktown Cancer and Haematology Centre, Blacktown Hospital, Western Sydney Local Health District, New South Wales, Australia

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Ida Madsen Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, New South Wales, Australia
Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia
Department of Gynaecological Oncology, Westmead Hospital, Western Sydney Local Health District, New South Wales, Australia

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Paul R Harnett Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, New South Wales, Australia
Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia
Crown Princess Mary Cancer Centre, Westmead Hospital, Western Sydney Local Health District, New South Wales, Australia

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Anna DeFazio Centre for Cancer Research, The Westmead Institute for Medical Research, Sydney, New South Wales, Australia
Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia
Department of Gynaecological Oncology, Westmead Hospital, Western Sydney Local Health District, New South Wales, Australia
The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council New South Wales, Sydney, New South Wales, Australia

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recent molecular characterisation that LGSC has been fully designated as distinct from high-grade serous cancer (HGSC), with different pathogenesis, treatment response and clinical course. The benefit of this revised classification has been an

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-21-0191
Volume/Issue:
Volume 29: Issue 1
Free access
C Christofer Juhlin Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden
Department of Pathology and Cancer Diagnostics, Karolinska University Hospital, Stockholm, Sweden

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Ozgur Mete Department of Pathology, University Health Network, Toronto, ON, Canada
Endocrine Oncology Site, Princess Margaret Cancer Centre, Toronto, ON, Canada
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada

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Zubair W Baloch Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

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, completely follicular-patterned with PTC-related nuclear atypia lacking high-grade features (mitoses/necrosis) ( Hodak et al. 2016 , Thompson 2016 ). Most NIFTPs are RAS -driven or exhibit codon 601 BRAF mutations, and presence of BRAF p. V600E

Article Type:
Review Article
Collections:
Mini Reviews in Endocrine Related Cancer
DOI:
https://doi.org/10.1530/ERC-22-0293
Volume/Issue:
Volume 30: Issue 2
Free access
Larissa Akemi Kido Department of Structural and Functional Biology, Structural and Cellular Biology Postgraduate Program, Institute of Biology, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil

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Fabio Montico Department of Structural and Functional Biology, Structural and Cellular Biology Postgraduate Program, Institute of Biology, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil

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Rafael Sauce Department of Structural and Functional Biology, Structural and Cellular Biology Postgraduate Program, Institute of Biology, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil

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Aline Barbosa Macedo Department of Structural and Functional Biology, Structural and Cellular Biology Postgraduate Program, Institute of Biology, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil

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Elaine Minatel Department of Structural and Functional Biology, Structural and Cellular Biology Postgraduate Program, Institute of Biology, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil

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Débora Barbosa Vendramini Costa Chemical, Biological and Agricultural Pluridisciplinary Research Center, CPQBA, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil
Department of Organic Chemistry, Institute of Chemistry, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil

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João Ernesto de Carvalho Chemical, Biological and Agricultural Pluridisciplinary Research Center, CPQBA, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil
Faculty of Pharmaceutical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil

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Ronaldo Aloise Pilli Department of Organic Chemistry, Institute of Chemistry, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil

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Valeria Helena Alves Cagnon Department of Structural and Functional Biology, Structural and Cellular Biology Postgraduate Program, Institute of Biology, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil

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following specifications: (1) normal tissue (NT); (2) low-grade prostatic intraepithelial neoplasia (LGPIN); (3) high-grade prostatic intraepithelial neoplasia (HGPIN); (4) well-differentiated adenocarcinoma; and (5) undifferentiated adenocarcinoma ( Fig. 1A

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-15-0540
Volume/Issue:
Volume 23: Issue 4
Free access
M Cives Department of Gastrointestinal Oncology, Department of Medicine, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA

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P L Kunz Department of Gastrointestinal Oncology, Department of Medicine, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA

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B Morse Department of Gastrointestinal Oncology, Department of Medicine, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA

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D Coppola
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M J Schell Department of Gastrointestinal Oncology, Department of Medicine, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA

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T Campos Department of Gastrointestinal Oncology, Department of Medicine, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA

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P T Nguyen Department of Gastrointestinal Oncology, Department of Medicine, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA

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P Nandoskar Department of Gastrointestinal Oncology, Department of Medicine, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA

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V Khandelwal Department of Gastrointestinal Oncology, Department of Medicine, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA

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J R Strosberg Department of Gastrointestinal Oncology, Department of Medicine, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA

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have locally unresectable or metastatic grade 1 or 2 pancreatic or extra-pancreatic NETs. Mitotic count and ki-67 thresholds for the tumor grade index were based on the World Health Organization (WHO) 2010 classification ( Rindi & Arnold 2010

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-14-0360
Volume/Issue:
Volume 22: Issue 1
Free access
J R Strosberg Department of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA

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M Cives Department of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA

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J Hwang Department of Medicine and The UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA

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T Weber Department of Medicine and The UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA

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M Nickerson Department of Medicine and The UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA

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C E Atreya Department of Medicine and The UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA

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A Venook Department of Medicine and The UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA

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R K Kelley Department of Medicine and The UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA

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T Valone Department of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA

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B Morse Department of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA

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D Coppola Department of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA

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E K Bergsland Department of Medicine and The UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA

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classification ( Rindi & Arnold 2010 ). Patients with poorly differentiated or high-grade tumors were excluded. Patients were required to have evidence of progressive disease within 12months of study entry. Any number of prior systemic or locoregional treatments

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-16-0008
Volume/Issue:
Volume 23: Issue 5
Free access
Catherine T Choy Division of Biomedical Sciences, Academic Neurosurgery Unit, Division of Clinical Sciences, Department of Cellular Pathology, Division of Cardiac and Vascular Sciences, Department of Electrical and Electronic Engineering, St George's Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK

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Haseong Kim Division of Biomedical Sciences, Academic Neurosurgery Unit, Division of Clinical Sciences, Department of Cellular Pathology, Division of Cardiac and Vascular Sciences, Department of Electrical and Electronic Engineering, St George's Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK

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Ji-Young Lee Division of Biomedical Sciences, Academic Neurosurgery Unit, Division of Clinical Sciences, Department of Cellular Pathology, Division of Cardiac and Vascular Sciences, Department of Electrical and Electronic Engineering, St George's Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK

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David M Williams Division of Biomedical Sciences, Academic Neurosurgery Unit, Division of Clinical Sciences, Department of Cellular Pathology, Division of Cardiac and Vascular Sciences, Department of Electrical and Electronic Engineering, St George's Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK

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David Palethorpe Division of Biomedical Sciences, Academic Neurosurgery Unit, Division of Clinical Sciences, Department of Cellular Pathology, Division of Cardiac and Vascular Sciences, Department of Electrical and Electronic Engineering, St George's Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK

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Greg Fellows Division of Biomedical Sciences, Academic Neurosurgery Unit, Division of Clinical Sciences, Department of Cellular Pathology, Division of Cardiac and Vascular Sciences, Department of Electrical and Electronic Engineering, St George's Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK

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Alan J Wright Division of Biomedical Sciences, Academic Neurosurgery Unit, Division of Clinical Sciences, Department of Cellular Pathology, Division of Cardiac and Vascular Sciences, Department of Electrical and Electronic Engineering, St George's Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK

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Ken Laing Division of Biomedical Sciences, Academic Neurosurgery Unit, Division of Clinical Sciences, Department of Cellular Pathology, Division of Cardiac and Vascular Sciences, Department of Electrical and Electronic Engineering, St George's Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK

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Leslie R Bridges Division of Biomedical Sciences, Academic Neurosurgery Unit, Division of Clinical Sciences, Department of Cellular Pathology, Division of Cardiac and Vascular Sciences, Department of Electrical and Electronic Engineering, St George's Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK

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Franklyn A Howe Division of Biomedical Sciences, Academic Neurosurgery Unit, Division of Clinical Sciences, Department of Cellular Pathology, Division of Cardiac and Vascular Sciences, Department of Electrical and Electronic Engineering, St George's Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK

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Soo-Hyun Kim Division of Biomedical Sciences, Academic Neurosurgery Unit, Division of Clinical Sciences, Department of Cellular Pathology, Division of Cardiac and Vascular Sciences, Department of Electrical and Electronic Engineering, St George's Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK

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that KAL1 was differentially expressed according to the grade and type of tumor, showing an upregulation in high-grade primary brain tumors. We also found that anosmin-1 enhanced proliferation and motility of glioblastoma cells in vitro , formed a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-13-0181
Volume/Issue:
Volume 21: Issue 1
Open access
Nicole Panarelli Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA

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Kathrin Tyryshkin Laboratory of Translational RNA Biology, Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Ontario, Canada

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Justin Jong Mun Wong Laboratory of Translational RNA Biology, Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Ontario, Canada

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Adrianna Majewski Laboratory of Translational RNA Biology, Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Ontario, Canada

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Xiaojing Yang Laboratory of Translational RNA Biology, Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Ontario, Canada

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Theresa Scognamiglio Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA

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Michelle Kang Kim Center for Carcinoid and Neuroendocrine Tumors of Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, New York, USA

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Kimberly Bogardus HHMI, Laboratory of RNA Molecular Biology, The Rockefeller University, New York, New York, USA

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Thomas Tuschl HHMI, Laboratory of RNA Molecular Biology, The Rockefeller University, New York, New York, USA

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Yao-Tseng Chen Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA

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Neil Renwick Laboratory of Translational RNA Biology, Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Ontario, Canada
HHMI, Laboratory of RNA Molecular Biology, The Rockefeller University, New York, New York, USA

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improve as more samples are sequenced. Whether miR-328 would be a useful adjunct marker for assessing high-grade pancreatic NETs or for grading NETs in other anatomic sites is being explored. Direct comparison of our miRNA expression data with those

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-18-0244
Volume/Issue:
Volume 26: Issue 1
Free access