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Department of Urology, Xiangya Hospital, Central South University, Changsha, China
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Core Unit for Molecular Tumor Diagnostics (CMTD), National Center for Tumor Diseases (NCT), Partner Site Dresden, Dresden, Germany
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Department of Endocrinology, Diabetology and Clinical Nutrition, Universitätsspital Zürich (USZ) and University of Zurich (UZH), Zurich, Switzerland
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Department of Endocrinology, Diabetology and Clinical Nutrition, Universitätsspital Zürich (USZ) and University of Zurich (UZH), Zurich, Switzerland
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Introduction Paragangliomas (PGLs) are neuroendocrine tumors that originate from neural crest-derived cells of the sympathetic and parasympathetic ganglia. PGLs that arise from chromaffin cells of the adrenal medulla are named
Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA
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Introduction The Cancer Genome Atlas (TCGA) proposed that neuroendocrine tumors of adrenal paraganglia, pheochromocytomas (PCCs) and extra-adrenal paraganglia paragangliomas (PGLs, together denoted PPGL) can be divided into three main
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Hereditary Endocrine Cancer Group, Familial Cancer Clinic, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Confocal Microscopy Unit, Proteomics Unit, Endocrinology and Nutrition Service, Endocrinology and Nutrition Service, Department of Medical and Surgical Sciences, Human Cancer Genetics Programme, Spanish National Cancer Research Centre, Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, 28029 Madrid, Spain
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Hereditary Endocrine Cancer Group, Familial Cancer Clinic, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Confocal Microscopy Unit, Proteomics Unit, Endocrinology and Nutrition Service, Endocrinology and Nutrition Service, Department of Medical and Surgical Sciences, Human Cancer Genetics Programme, Spanish National Cancer Research Centre, Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, 28029 Madrid, Spain
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Hereditary Endocrine Cancer Group, Familial Cancer Clinic, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Confocal Microscopy Unit, Proteomics Unit, Endocrinology and Nutrition Service, Endocrinology and Nutrition Service, Department of Medical and Surgical Sciences, Human Cancer Genetics Programme, Spanish National Cancer Research Centre, Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, 28029 Madrid, Spain
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Hereditary Endocrine Cancer Group, Familial Cancer Clinic, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Confocal Microscopy Unit, Proteomics Unit, Endocrinology and Nutrition Service, Endocrinology and Nutrition Service, Department of Medical and Surgical Sciences, Human Cancer Genetics Programme, Spanish National Cancer Research Centre, Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, 28029 Madrid, Spain
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Hereditary Endocrine Cancer Group, Familial Cancer Clinic, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Confocal Microscopy Unit, Proteomics Unit, Endocrinology and Nutrition Service, Endocrinology and Nutrition Service, Department of Medical and Surgical Sciences, Human Cancer Genetics Programme, Spanish National Cancer Research Centre, Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, 28029 Madrid, Spain
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Hereditary Endocrine Cancer Group, Familial Cancer Clinic, Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Confocal Microscopy Unit, Proteomics Unit, Endocrinology and Nutrition Service, Endocrinology and Nutrition Service, Department of Medical and Surgical Sciences, Human Cancer Genetics Programme, Spanish National Cancer Research Centre, Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, 28029 Madrid, Spain
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Introduction Pheochromocytomas (PCCs) and paragangliomas (PGLs) are rare neuroendocrine tumors of neural crest origin. Up to an estimated 60% of PCCs/PGLs are associated with germline or somatic mutations in one many susceptibility genes ( RET
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Introduction The last 15 years have brought significant advances in our understanding of the genetic basis of hereditary syndromes with a predisposition to pheochromocytoma (PC) and paraganglioma (PGL) (PCPGL) development. In the 1990s the genetic
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Introduction Phaeochromocytomas (PHEO) of the adrenal gland and sympathetic paragangliomas (PGL) are catecholamine-producing tumours. Although 10–30% of these tumours metastasise, histopathological criteria that discriminate malignant from benign
Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Introduction Pheochromocytomas (PCs) are catecholamine-secreting tumours of chromaffin cells of the adrenal medulla and are closely related to paragangliomas (PGLs) which arise from sympathetic and parasympathetic chains ( Favier et al . 2005
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1st Department of Internal Medicine, Faculty of Medicine, Pavol Jozef Safarik University in Kosice, Kosice, Slovakia
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Introduction Pheochromocytomas (PHEOs) and paragangliomas (PGLs) are rare catecholamine-producing neuroendocrine tumors (NETs) arising in or outside the adrenal medulla, respectively ( Lenders et al . 2005 ). By definition, a PHEO is an intra
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Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands
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Introduction Paraganglioma–pheochromocytoma Paragangliomas and pheochromocytomas are neuroendocrine tumors that arise mainly in the adrenal medulla or paraganglia of the head and neck, but may also develop in abdominal or thoracic
Department of Endocrinology, Royal North Shore Hospital, Sydney, Australia
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Faculty of Medicine and Health, The University of Sydney, Sydney, Australia
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Faculty of Medicine and Health, The University of Sydney, Sydney, Australia
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Faculty of Medicine and Health, The University of Sydney, Sydney, Australia
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Cancer Genetics Laboratory, Kolling Institute, Royal North Shore Hospital, Sydney, Australia
Faculty of Medicine and Health, The University of Sydney, Sydney, Australia
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Introduction Phaeochromocytomas and paragangliomas (collectively termed PPGL) are rare neuroendocrine tumours originating from chromaffin cells of the adrenal medulla, and neuroendocrine paraganglia, respectively. Paragangliomas (PGLs) are
Department of Endocrinology, St Bartholomew’s Hospital, Barts Health NHS Trust. West Smithfield, London, UK
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Department of Endocrinology, St Bartholomew’s Hospital, Barts Health NHS Trust. West Smithfield, London, UK
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Department of Endocrinology, St Bartholomew’s Hospital, Barts Health NHS Trust. West Smithfield, London, UK
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Introduction Phaeochromocytoma and paragangliomas (PPGLs) are rare neuroendocrine tumours of the autonomic nervous system that can arise anywhere from the skull base to the pelvic floor and may secrete catecholamines. All PPGLs should be