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Varinder Jeet Australian Prostate Cancer Research Centre – Queensland, Department of Urologic Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Princess Alexandra Hospital, Translational Research Institute, Brisbane, Australia

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Gregor Tevz Australian Prostate Cancer Research Centre – Queensland, Department of Urologic Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Princess Alexandra Hospital, Translational Research Institute, Brisbane, Australia

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Melanie Lehman Australian Prostate Cancer Research Centre – Queensland, Department of Urologic Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Princess Alexandra Hospital, Translational Research Institute, Brisbane, Australia
Australian Prostate Cancer Research Centre – Queensland, Department of Urologic Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Princess Alexandra Hospital, Translational Research Institute, Brisbane, Australia

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Brett Hollier Australian Prostate Cancer Research Centre – Queensland, Department of Urologic Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Princess Alexandra Hospital, Translational Research Institute, Brisbane, Australia

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Colleen Nelson Australian Prostate Cancer Research Centre – Queensland, Department of Urologic Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Princess Alexandra Hospital, Translational Research Institute, Brisbane, Australia
Australian Prostate Cancer Research Centre – Queensland, Department of Urologic Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology, Princess Alexandra Hospital, Translational Research Institute, Brisbane, Australia

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W Bentley B Shao R 2011 Role of YKL-40 in the angiogenesis, radioresistance, and progression of glioblastoma . Journal of Biological Chemistry 286 15332 – 15343 . ( doi:10.1074/jbc.M110.212514 ). Freedman VH Shin SI 1974 Cellular

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N Burrows School of Pharmacy and Pharmaceutical Sciences, Department of Endocrinology, Department of Pathology, Experimental and Surgical Oncology, Academic Department of Radiation Oncology, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK

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J Resch School of Pharmacy and Pharmaceutical Sciences, Department of Endocrinology, Department of Pathology, Experimental and Surgical Oncology, Academic Department of Radiation Oncology, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK

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R L Cowen School of Pharmacy and Pharmaceutical Sciences, Department of Endocrinology, Department of Pathology, Experimental and Surgical Oncology, Academic Department of Radiation Oncology, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK

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R von Wasielewski School of Pharmacy and Pharmaceutical Sciences, Department of Endocrinology, Department of Pathology, Experimental and Surgical Oncology, Academic Department of Radiation Oncology, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK

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C Hoang-Vu School of Pharmacy and Pharmaceutical Sciences, Department of Endocrinology, Department of Pathology, Experimental and Surgical Oncology, Academic Department of Radiation Oncology, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK

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C M West School of Pharmacy and Pharmaceutical Sciences, Department of Endocrinology, Department of Pathology, Experimental and Surgical Oncology, Academic Department of Radiation Oncology, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK

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K J Williams School of Pharmacy and Pharmaceutical Sciences, Department of Endocrinology, Department of Pathology, Experimental and Surgical Oncology, Academic Department of Radiation Oncology, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK

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G Brabant School of Pharmacy and Pharmaceutical Sciences, Department of Endocrinology, Department of Pathology, Experimental and Surgical Oncology, Academic Department of Radiation Oncology, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK

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Chinje EC Jaffar M Sheppard FC Telfer BA Wind S Stratford IJ 2004 Hypoxia targeted gene therapy to increase the efficacy of tirapazamine as an adjuvant to radiotherapy: reversing tumor radioresistance and effecting

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Nely Díaz-Mejía Vall d’Hebron Institute of Oncology (VHIO) and Vall d’Hebron University Hospital, Barcelona, Spain

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David García-Illescas Vall d’Hebron Institute of Oncology (VHIO) and Vall d’Hebron University Hospital, Barcelona, Spain

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Rafael Morales-Barrera Vall d’Hebron Institute of Oncology (VHIO) and Vall d’Hebron University Hospital, Barcelona, Spain

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Cristina Suarez Vall d’Hebron Institute of Oncology (VHIO) and Vall d’Hebron University Hospital, Barcelona, Spain

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Jacques Planas Vall d’Hebron Institute of Oncology (VHIO) and Vall d’Hebron University Hospital, Barcelona, Spain

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Xavier Maldonado Vall d’Hebron Institute of Oncology (VHIO) and Vall d’Hebron University Hospital, Barcelona, Spain

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Joan Carles Vall d’Hebron Institute of Oncology (VHIO) and Vall d’Hebron University Hospital, Barcelona, Spain

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Joaquin Mateo Vall d’Hebron Institute of Oncology (VHIO) and Vall d’Hebron University Hospital, Barcelona, Spain

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recombination proteins to offset chemoresistance and radioresistance . Cancer Research 68 605 – 614 . ( https://doi.org/10.1158/0008-5472.CAN-07-5472 ) Chen X Chen Z Zheng B Tang W 2019 Targeting NPRL2 to enhance the efficacy of Olaparib in

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Laura A Marlow Departments of Cancer Biology, Internal Medicine, Endocrine Malignancy Working Group

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Ilah Bok Departments of Cancer Biology, Internal Medicine, Endocrine Malignancy Working Group

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Robert C Smallridge Departments of Cancer Biology, Internal Medicine, Endocrine Malignancy Working Group
Departments of Cancer Biology, Internal Medicine, Endocrine Malignancy Working Group
Departments of Cancer Biology, Internal Medicine, Endocrine Malignancy Working Group

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John A Copland Departments of Cancer Biology, Internal Medicine, Endocrine Malignancy Working Group
Departments of Cancer Biology, Internal Medicine, Endocrine Malignancy Working Group

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radioresistance in HeLa cells by preventing post-mitotic cell death . Oncogene 21 5998 – 6006 . ( doi:10.1038/sj.onc.1205746 ). Adnane J Muro-Cacho C Mathews L Sebti SM Munoz-Antonia T 2002 Suppression of RhoB expression in invasive carcinoma

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Zhenying Guo Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Zhejiang, China

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Heather Hardin Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Zhejiang, China

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Ricardo V Lloyd Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Zhejiang, China

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self-renewal, and can propagate tumors when injected into immune-compromised mice. The CD133(+) ATC cells exhibited higher radioresistance and higher expression of OCT4 ( POU5F1 ), NANOG , SOX2 , LIN28 ( LIN28A ), and GLUT1 ( SLC2A1 ) in cell

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Elke Tatjana Aristizabal Prada Medizinische Klinik und Poliklinik IV, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München (KUM), Ludwig-Maximilians-University, Munich, Germany

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Gerald Spöttl Medizinische Klinik und Poliklinik IV, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München (KUM), Ludwig-Maximilians-University, Munich, Germany

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Julian Maurer Medizinische Klinik und Poliklinik IV, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München (KUM), Ludwig-Maximilians-University, Munich, Germany

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Michael Lauseker Institute for Medical Information Sciences, Biometry, and Epidemiology, Campus Grosshadern, Ludwig-Maximilians-University of Munich, Munich, Germany

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Eva Jolanthe Koziolek Department of Nuclear Medicine, University Medical Center Charité, Berlin, Germany
German Cancer Consortium (DKTK), Heidelberg, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany

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Jörg Schrader I. Medizinische Klinik und Poliklinik, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany

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Ashley Grossman Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK
Royal Free Hospital ENETS Centre of Excellence, London, UK

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Karel Pacak Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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Felix Beuschlein Medizinische Klinik und Poliklinik IV, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München (KUM), Ludwig-Maximilians-University, Munich, Germany
Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, Universitätsspital Zürich, Zurich, Switzerland

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Christoph Joseph Auernhammer Medizinische Klinik und Poliklinik IV, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München (KUM), Ludwig-Maximilians-University, Munich, Germany

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Svenja Nölting Medizinische Klinik und Poliklinik IV, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München (KUM), Ludwig-Maximilians-University, Munich, Germany

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Shimura T 2011 Acquired radioresistance of cancer and the AKT/GSK3beta/cyclin D1 overexpression cycle . Journal of Radiation Research 52 539 – 544 . ( https://doi.org/10.1269/jrr.11098 ) 21881296 10.1269/jrr.11098 Shipkova M Hesselink DA

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Rhonda L Bitting Divisions of Medical Oncology and Urology, Duke Cancer Institute, Duke University, DUMC Box 102002, Durham, North Carolina 27710, USA

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Andrew J Armstrong Divisions of Medical Oncology and Urology, Duke Cancer Institute, Duke University, DUMC Box 102002, Durham, North Carolina 27710, USA

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Intracellular signaling pathways regulating radioresistance of human prostate carcinoma cells . Proteomics 8 4521 – 4533 . ( doi:10.1002/pmic.200800113 ). Small EJ Fontana J Tannir N DiPaola RS Wilding G

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Federica Morani Laboratory of Molecular Pathology, Unit of Oncology, Department of Health Sciences

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Rossella Titone Laboratory of Molecular Pathology, Unit of Oncology, Department of Health Sciences

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Loredana Pagano Laboratory of Molecular Pathology, Unit of Oncology, Department of Health Sciences

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Alessandra Galetto Laboratory of Molecular Pathology, Unit of Oncology, Department of Health Sciences

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Oscar Alabiso Laboratory of Molecular Pathology, Unit of Oncology, Department of Health Sciences

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Gianluca Aimaretti Laboratory of Molecular Pathology, Unit of Oncology, Department of Health Sciences

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Ciro Isidoro Laboratory of Molecular Pathology, Unit of Oncology, Department of Health Sciences

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Yan-Chao F Xiao Y Guang-Xiu W Zhi-Fan J Pei-Yu P Qing-Yu Z Chun-Sheng K 2010 MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN . BMC Cancer 10 367 . ( doi:10

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H H Milioli Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia
St Vincent’s Clinical School, UNSW Sydney, Sydney, New South Wales, Australia

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S Alexandrou Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia

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E Lim Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia
St Vincent’s Clinical School, UNSW Sydney, Sydney, New South Wales, Australia

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C E Caldon Garvan Institute of Medical Research, Darlinghurst, Sydney, New South Wales, Australia
St Vincent’s Clinical School, UNSW Sydney, Sydney, New South Wales, Australia

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.1530/ERC-18-0317 ) Post AEM Bussink J Sweep FCGJ Span PN 2019 Changes in DNA damage repair gene expression and cell cycle gene expression do not explain radioresistance in tamoxifen-resistant breast cancer . Oncology Research 28 33 – 40

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Livia Lamartina Gustave Roussy, Department of Nuclear Medicine and Endocrine Oncology, Villejuif, France

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Nadège Anizan Department of Medical Physics, Gustave Roussy and University Paris Saclay, Villejuif, France

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Corinne Dupuy UMR 8200/9019 CNRS Paris-Saclay, Genome Integrity and Cancers, Gustave Roussy and University Paris Saclay, Villejuif, France

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Sophie Leboulleux Gustave Roussy, Department of Nuclear Medicine and Endocrine Oncology, Villejuif, France

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Martin Schlumberger Gustave Roussy, Department of Nuclear Medicine and Endocrine Oncology, Villejuif, France

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Jhiang S Ringel MD et al . 2019 Inhibiting BRAF Oncogene-Mediated Radioresistance Effectively Radiosensitizes BRAFV600E-Mutant Thyroid Cancer Cells by Constraining DNA Double-Strand Break Repair . Clinical Cancer Research 25 4749 – 4760

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