Search Results

You are looking at 21 - 30 of 100 items for :

  • Refine by access: All content x
Clear All
Cécile M Vouyovitch Centre de Recherche en Cancérologie de Lyon, UMR INSERM 1052-CNRS 5286, Centre Léon Bérard, Université Claude Bernard Lyon I, Université de Lyon, Lyon, France

Search for other papers by Cécile M Vouyovitch in
Google Scholar
PubMed
Close
,
Jo K Perry Liggins Institute, University of Auckland, Auckland, New Zealand

Search for other papers by Jo K Perry in
Google Scholar
PubMed
Close
,
Dong Xu Liu Liggins Institute, University of Auckland, Auckland, New Zealand

Search for other papers by Dong Xu Liu in
Google Scholar
PubMed
Close
,
Laurent Bezin Centre de Recherche en Neurosciences de Lyon, UMR INSERM U1028-CNRS5292, Université de Lyon, Lyon, France

Search for other papers by Laurent Bezin in
Google Scholar
PubMed
Close
,
Eric Vilain Department of Human Genetics, University of California, Los Angeles, California, USA

Search for other papers by Eric Vilain in
Google Scholar
PubMed
Close
,
Jean-Jacques Diaz Centre de Recherche en Cancérologie de Lyon, UMR INSERM 1052-CNRS 5286, Centre Léon Bérard, Université Claude Bernard Lyon I, Université de Lyon, Lyon, France

Search for other papers by Jean-Jacques Diaz in
Google Scholar
PubMed
Close
,
Peter E Lobie Cancer Science Institute of Singapore and Department of Pharmacology, National University of Singapore, Singapore, Republic of Singapore

Search for other papers by Peter E Lobie in
Google Scholar
PubMed
Close
, and
Hichem C Mertani Centre de Recherche en Cancérologie de Lyon, UMR INSERM 1052-CNRS 5286, Centre Léon Bérard, Université Claude Bernard Lyon I, Université de Lyon, Lyon, France

Search for other papers by Hichem C Mertani in
Google Scholar
PubMed
Close

carcinogenesis is still poorly defined. It has been demonstrated that WNT2 which is functionally related to WNT4 is an activity-dependent c-fos cAMP-response element binding protein (CREB)-responsive gene in neurons ( Wayman et al. 2006 ). The level of CREB

Free access
Alastair Davies Vancouver Prostate Centre, Vancouver, British Columbia, Canada
Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, British Columbia, Canada

Search for other papers by Alastair Davies in
Google Scholar
PubMed
Close
,
Amina Zoubeidi Vancouver Prostate Centre, Vancouver, British Columbia, Canada
Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, British Columbia, Canada

Search for other papers by Amina Zoubeidi in
Google Scholar
PubMed
Close
, and
Luke A Selth Flinders Centre for Innovation in Cancer, Flinders University, College of Medicine and Public Health, Bedford Park, South Australia, Australia
Dame Roma Mitchell Cancer Research Laboratories and Freemasons Foundation Centre for Men’s Health, Adelaide Medical School, The University of Adelaide, Adelaide, South Australia, Australia

Search for other papers by Luke A Selth in
Google Scholar
PubMed
Close

-response element binding protein (CREB) activation in prostate cancer models; CREB-induced H3K27me3, and neuroendocrine differentiation could be blocked by EZH2 inhibition ( Zhang et al . 2018 ). Mechanistically, activation of the CREB/EZH2 axis facilitates

Free access
T Kogai
Search for other papers by T Kogai in
Google Scholar
PubMed
Close
,
K Taki
Search for other papers by K Taki in
Google Scholar
PubMed
Close
, and
G A Brent
Search for other papers by G A Brent in
Google Scholar
PubMed
Close

regulated by these trans acting factors although with some variation among species ( Endo et al. 1997 , Ohmori et al. 1998 , Ohno et al. 1999 , Taki et al. 2002 ). The NUE requires Pax-8 and cAMP-responsive element binding protein (CREB) for its

Free access
Dang Vu-Phan Cellular and Molecular Biology Graduate Program, Division of Metabolism, Department of Comparative Medicine, Division of Hematology and Oncology, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA

Search for other papers by Dang Vu-Phan in
Google Scholar
PubMed
Close
,
Vladimir Grachtchouk Cellular and Molecular Biology Graduate Program, Division of Metabolism, Department of Comparative Medicine, Division of Hematology and Oncology, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA

Search for other papers by Vladimir Grachtchouk in
Google Scholar
PubMed
Close
,
Jingcheng Yu Cellular and Molecular Biology Graduate Program, Division of Metabolism, Department of Comparative Medicine, Division of Hematology and Oncology, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA

Search for other papers by Jingcheng Yu in
Google Scholar
PubMed
Close
,
Lesley A Colby Cellular and Molecular Biology Graduate Program, Division of Metabolism, Department of Comparative Medicine, Division of Hematology and Oncology, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA

Search for other papers by Lesley A Colby in
Google Scholar
PubMed
Close
,
Max S Wicha Cellular and Molecular Biology Graduate Program, Division of Metabolism, Department of Comparative Medicine, Division of Hematology and Oncology, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA

Search for other papers by Max S Wicha in
Google Scholar
PubMed
Close
, and
Ronald J Koenig Cellular and Molecular Biology Graduate Program, Division of Metabolism, Department of Comparative Medicine, Division of Hematology and Oncology, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA

Search for other papers by Ronald J Koenig in
Google Scholar
PubMed
Close

& Spiegelman 2008 ). Modulation of PPARG-regulated pathways is thought to be important in PPFP carcinogenesis, and this is consistent with the observation that a different translocation fusing PPARG to the gene CREB3L2 also has been identified in FTC ( Lui

Free access
Xiao-hui Luo Department of Urology, Baoji Center Hospital, Baoji, Shaanxi Province, People’s Republic of China

Search for other papers by Xiao-hui Luo in
Google Scholar
PubMed
Close
,
Jian-zhou Liu Department of Urology, Baoji Center Hospital, Baoji, Shaanxi Province, People’s Republic of China

Search for other papers by Jian-zhou Liu in
Google Scholar
PubMed
Close
,
Bo Wang Department of Urology, Baoji Center Hospital, Baoji, Shaanxi Province, People’s Republic of China

Search for other papers by Bo Wang in
Google Scholar
PubMed
Close
,
Qun-li Men Department of Urology, Baoji Center Hospital, Baoji, Shaanxi Province, People’s Republic of China

Search for other papers by Qun-li Men in
Google Scholar
PubMed
Close
,
Yu-quan Ju Department of Urology, Baoji Center Hospital, Baoji, Shaanxi Province, People’s Republic of China

Search for other papers by Yu-quan Ju in
Google Scholar
PubMed
Close
,
Feng-yan Yin Department of Urology, Baoji Center Hospital, Baoji, Shaanxi Province, People’s Republic of China

Search for other papers by Feng-yan Yin in
Google Scholar
PubMed
Close
,
Chao Zheng Department of Urology, Baoji Center Hospital, Baoji, Shaanxi Province, People’s Republic of China

Search for other papers by Chao Zheng in
Google Scholar
PubMed
Close
, and
Wei Li Department of Human Anatomy, Histology and Embryology, Fourth Military Medical University, Xi’an, Shaanxi Province, People’s Republic of China

Search for other papers by Wei Li in
Google Scholar
PubMed
Close

transcription. Of note, multiple putative cis -regulatory elements have been previously identified in the HMOX1 promoter region including −146 to −37 bp for CREB ( Astort et al . 2016 ), −44 bp for Nrf2 ( Potteti et al . 2016 ) and −1036 to +1 bp for Sp1

Free access
Yan Huang Department of Gynecology, Department of Gynecologic Oncology, Systems Biology, Experimental Therapeutics, Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, 419 Fang Xie Road, Shanghai 200011, People's Republic of China
Department of Gynecology, Department of Gynecologic Oncology, Systems Biology, Experimental Therapeutics, Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, 419 Fang Xie Road, Shanghai 200011, People's Republic of China

Search for other papers by Yan Huang in
Google Scholar
PubMed
Close
,
Hongyan Jin Department of Gynecology, Department of Gynecologic Oncology, Systems Biology, Experimental Therapeutics, Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, 419 Fang Xie Road, Shanghai 200011, People's Republic of China

Search for other papers by Hongyan Jin in
Google Scholar
PubMed
Close
,
Yingtao Liu Department of Gynecology, Department of Gynecologic Oncology, Systems Biology, Experimental Therapeutics, Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, 419 Fang Xie Road, Shanghai 200011, People's Republic of China

Search for other papers by Yingtao Liu in
Google Scholar
PubMed
Close
,
Jiayi Zhou Department of Gynecology, Department of Gynecologic Oncology, Systems Biology, Experimental Therapeutics, Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, 419 Fang Xie Road, Shanghai 200011, People's Republic of China

Search for other papers by Jiayi Zhou in
Google Scholar
PubMed
Close
,
Jingxin Ding Department of Gynecology, Department of Gynecologic Oncology, Systems Biology, Experimental Therapeutics, Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, 419 Fang Xie Road, Shanghai 200011, People's Republic of China

Search for other papers by Jingxin Ding in
Google Scholar
PubMed
Close
,
Kwai Wa Cheng Department of Gynecology, Department of Gynecologic Oncology, Systems Biology, Experimental Therapeutics, Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, 419 Fang Xie Road, Shanghai 200011, People's Republic of China

Search for other papers by Kwai Wa Cheng in
Google Scholar
PubMed
Close
,
Yinhua Yu Department of Gynecology, Department of Gynecologic Oncology, Systems Biology, Experimental Therapeutics, Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, 419 Fang Xie Road, Shanghai 200011, People's Republic of China
Department of Gynecology, Department of Gynecologic Oncology, Systems Biology, Experimental Therapeutics, Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, 419 Fang Xie Road, Shanghai 200011, People's Republic of China

Search for other papers by Yinhua Yu in
Google Scholar
PubMed
Close
, and
Youji Feng Department of Gynecology, Department of Gynecologic Oncology, Systems Biology, Experimental Therapeutics, Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, 419 Fang Xie Road, Shanghai 200011, People's Republic of China
Department of Gynecology, Department of Gynecologic Oncology, Systems Biology, Experimental Therapeutics, Department of Obstetrics and Gynecology, Obstetrics and Gynecology Hospital of Fudan University, 419 Fang Xie Road, Shanghai 200011, People's Republic of China

Search for other papers by Youji Feng in
Google Scholar
PubMed
Close

, an anti-cJUN antibody, an anti-pAKT (Ser473) antibody, an anti-AKT antibody, an anti-pCREB (Ser133) antibody, an anti-CREB antibody, an anti-pIκB (Ser32) antibody, an anti-IκB antibody, and an anti-DR5 antibody were purchased from Cell Signaling

Free access
Srilatha Swami Department of Medicine-Endocrinology, Stanford University School of Medicine, Stanford, CA, USA

Search for other papers by Srilatha Swami in
Google Scholar
PubMed
Close
,
Aruna V Krishnan Department of Pediatrics-Endocrinology, Stanford University School of Medicine, Stanford, CA, USA

Search for other papers by Aruna V Krishnan in
Google Scholar
PubMed
Close
,
Jasmaine Williams Department of Pediatrics-Endocrinology, Stanford University School of Medicine, Stanford, CA, USA
Cancer Biology Program, Stanford University School of Medicine, Stanford, CA, USA

Search for other papers by Jasmaine Williams in
Google Scholar
PubMed
Close
,
Abhishek Aggarwal Department of Pediatrics-Endocrinology, Stanford University School of Medicine, Stanford, CA, USA

Search for other papers by Abhishek Aggarwal in
Google Scholar
PubMed
Close
,
Megan A Albertelli Department of Comparative Medicine, Stanford University School of Medicine, Stanford, CA, USA

Search for other papers by Megan A Albertelli in
Google Scholar
PubMed
Close
,
Ronald L Horst Heartland Assays Inc, Ames, IA, USA

Search for other papers by Ronald L Horst in
Google Scholar
PubMed
Close
,
Brian J Feldman Department of Pediatrics-Endocrinology, Stanford University School of Medicine, Stanford, CA, USA
Cancer Biology Program, Stanford University School of Medicine, Stanford, CA, USA
Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, USA
Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA

Search for other papers by Brian J Feldman in
Google Scholar
PubMed
Close
, and
David Feldman Department of Medicine-Endocrinology, Stanford University School of Medicine, Stanford, CA, USA
Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA

Search for other papers by David Feldman in
Google Scholar
PubMed
Close

negatively regulates the actions of CREB -dependent aromatase, the enzyme that catalyzes the synthesis of estrogens in breast adipose tissue, via phosphorylation of CRTC2 , a transcription factor required for the activation of the aromatase promoter PII in

Free access
Lesley-Ann Martin
Search for other papers by Lesley-Ann Martin in
Google Scholar
PubMed
Close
,
Ian Farmer
Search for other papers by Ian Farmer in
Google Scholar
PubMed
Close
,
Stephen R D Johnston
Search for other papers by Stephen R D Johnston in
Google Scholar
PubMed
Close
,
Simak Ali
Search for other papers by Simak Ali in
Google Scholar
PubMed
Close
, and
Mitch Dowsett
Search for other papers by Mitch Dowsett in
Google Scholar
PubMed
Close

) whilst downstream partners such as p90 RSK can phosphorylate and enhance the activity of CREB binding protein (CBP) ( Nakajima et al. 1996 ) together with other factors associated with the basal transcription machinery. These findings may account for

Free access
Garcilaso Riesco-Eizaguirre Instituto de Investigaciones Biomédicas ‘Alberto Sols’, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, Madrid, Spain
Department of Endocrinology and Nutrition, Hospital Universitario de Móstoles, Madrid, Spain
Molecular Endocrinology Group, Faculty of Medicine, Universidad Francisco de Vitoria, Madrid, Spain
Centro de Investigaciones Biomédicas en Red, CIBERONC, Instituto de Salud Carlos III, Madrid, Spain

Search for other papers by Garcilaso Riesco-Eizaguirre in
Google Scholar
PubMed
Close
,
Pilar Santisteban Instituto de Investigaciones Biomédicas ‘Alberto Sols’, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, Madrid, Spain
Centro de Investigaciones Biomédicas en Red, CIBERONC, Instituto de Salud Carlos III, Madrid, Spain

Search for other papers by Pilar Santisteban in
Google Scholar
PubMed
Close
, and
Antonio De la Vieja Centro de Investigaciones Biomédicas en Red, CIBERONC, Instituto de Salud Carlos III, Madrid, Spain
Endocrine Tumors Unit, Unidad Funcional de Investigación en Enfermedades Crónicas (UFIEC), Instituto de Salud Carlos III, Madrid, Spain

Search for other papers by Antonio De la Vieja in
Google Scholar
PubMed
Close

(negatively regulated by SMAD3) binds to the NUE region and has a major role in NIS upregulation. Many other factors have been shown to bind to NUE regions such as CRE-like binding site (positively regulated by CREM, CREB1, ATF2, c-Fos, and c-Jun, or

Free access
Maria Isabel C Vieira Cordioli Genetic Bases of Thyroid Tumors Laboratory, Division of Endocrinology, Division of Genetics, Department of Morphology and Genetics and Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Pedro de Toledo 669, 11 andar, 04039‐032, São Paulo, SP, Brazil

Search for other papers by Maria Isabel C Vieira Cordioli in
Google Scholar
PubMed
Close
,
Lais Moraes Genetic Bases of Thyroid Tumors Laboratory, Division of Endocrinology, Division of Genetics, Department of Morphology and Genetics and Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Pedro de Toledo 669, 11 andar, 04039‐032, São Paulo, SP, Brazil

Search for other papers by Lais Moraes in
Google Scholar
PubMed
Close
,
Adriano Namo Cury Genetic Bases of Thyroid Tumors Laboratory, Division of Endocrinology, Division of Genetics, Department of Morphology and Genetics and Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Pedro de Toledo 669, 11 andar, 04039‐032, São Paulo, SP, Brazil

Search for other papers by Adriano Namo Cury in
Google Scholar
PubMed
Close
, and
Janete M Cerutti Genetic Bases of Thyroid Tumors Laboratory, Division of Endocrinology, Division of Genetics, Department of Morphology and Genetics and Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Pedro de Toledo 669, 11 andar, 04039‐032, São Paulo, SP, Brazil

Search for other papers by Janete M Cerutti in
Google Scholar
PubMed
Close

TRK1, CREB3L2-PPARG. The other somatic mutation groups include BRAF V600_K601E and TSHR S425I. The prevalence of RET/PTC isoforms is show in detail in the bottom panel. The prevalence and categories of mutations are detailed in Supplementary Tables

Free access