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Lei Qiao Department of Breast and Thyroid Surgery, Xinjiang Medical University Affiliated Tumor Hospital, Urumqi, Xinjiang Uygur Autonomous Region, China

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Chao Dong Department of Breast and Thyroid Surgery, Xinjiang Medical University Affiliated Tumor Hospital, Urumqi, Xinjiang Uygur Autonomous Region, China

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Wenlei Jia Department of Breast and Thyroid Surgery, Xinjiang Medical University Affiliated Tumor Hospital, Urumqi, Xinjiang Uygur Autonomous Region, China

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Gang Sun Department of Breast and Thyroid Surgery, Xinjiang Medical University Affiliated Tumor Hospital, Urumqi, Xinjiang Uygur Autonomous Region, China

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miRNA is dysregulated in various cancers and plays roles as either oncogenes or tumor suppressors, which are tightly related to tumor development and occurrence ( Calin & Croce 2006 ), as well as chemoresistance ( Ashrafizadeh et al. 2020 a ). Rab5

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Hans K Ghayee
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Bas Havekes Division of Endocrinology, Reproductive Biology and Medicine Program, Department of Endocrinology and Metabolism, Institute of Clinical Chemistry & Laboratory Medicine and Department of Medicine, Department of Medicine, Medical Oncology Branch, Department of Internal Medicine, Southwesterm Medical Center, University of Texas, 5323 Harry Hines Boulevard, Suite Y-5.318, Dallas, Texas 75390-8857, USA

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Eleonora P M Corssmit Division of Endocrinology, Reproductive Biology and Medicine Program, Department of Endocrinology and Metabolism, Institute of Clinical Chemistry & Laboratory Medicine and Department of Medicine, Department of Medicine, Medical Oncology Branch, Department of Internal Medicine, Southwesterm Medical Center, University of Texas, 5323 Harry Hines Boulevard, Suite Y-5.318, Dallas, Texas 75390-8857, USA

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Graeme Eisenhofer Division of Endocrinology, Reproductive Biology and Medicine Program, Department of Endocrinology and Metabolism, Institute of Clinical Chemistry & Laboratory Medicine and Department of Medicine, Department of Medicine, Medical Oncology Branch, Department of Internal Medicine, Southwesterm Medical Center, University of Texas, 5323 Harry Hines Boulevard, Suite Y-5.318, Dallas, Texas 75390-8857, USA

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Stephen R Hammes
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Zahid Ahmad
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Alexander Tessnow
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Ivica Lazúrová Division of Endocrinology, Reproductive Biology and Medicine Program, Department of Endocrinology and Metabolism, Institute of Clinical Chemistry & Laboratory Medicine and Department of Medicine, Department of Medicine, Medical Oncology Branch, Department of Internal Medicine, Southwesterm Medical Center, University of Texas, 5323 Harry Hines Boulevard, Suite Y-5.318, Dallas, Texas 75390-8857, USA

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Karen T Adams Division of Endocrinology, Reproductive Biology and Medicine Program, Department of Endocrinology and Metabolism, Institute of Clinical Chemistry & Laboratory Medicine and Department of Medicine, Department of Medicine, Medical Oncology Branch, Department of Internal Medicine, Southwesterm Medical Center, University of Texas, 5323 Harry Hines Boulevard, Suite Y-5.318, Dallas, Texas 75390-8857, USA

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Antonio T Fojo Division of Endocrinology, Reproductive Biology and Medicine Program, Department of Endocrinology and Metabolism, Institute of Clinical Chemistry & Laboratory Medicine and Department of Medicine, Department of Medicine, Medical Oncology Branch, Department of Internal Medicine, Southwesterm Medical Center, University of Texas, 5323 Harry Hines Boulevard, Suite Y-5.318, Dallas, Texas 75390-8857, USA

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Karel Pacak Division of Endocrinology, Reproductive Biology and Medicine Program, Department of Endocrinology and Metabolism, Institute of Clinical Chemistry & Laboratory Medicine and Department of Medicine, Department of Medicine, Medical Oncology Branch, Department of Internal Medicine, Southwesterm Medical Center, University of Texas, 5323 Harry Hines Boulevard, Suite Y-5.318, Dallas, Texas 75390-8857, USA

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Richard J Auchus
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vertebrae. He underwent a partial thoracic corpectomy, as well as a posterior thoracic decompression and fixation of T1–T5 with an iliac crest bone graft. Histopathology revealed a PGL with areas of necrosis. Family history was negative for both PGLs and

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Tobias Else Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan, 2560E MSRB2, 1150 West Medical Center Drive, Ann Arbor, Michigan 48109‐5674, USA

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hereditary PGL syndromes (PGL1–5) ( Baysal et al . 2000 , Niemann & Muller 2000 , Astuti et al . 2001 , Hao et al . 2009 , Burnichon et al . 2010 ). More recently, PCPGLs have been suggested to be part of other syndromes, such as hereditary

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Françoise Galland Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Ludovic Lacroix Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Patrick Saulnier Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Philippe Dessen Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Geri Meduri Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Michèle Bernier Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Stéphane Gaillard Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Jean Guibourdenche Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Thierry Fournier Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Danièle Evain-Brion Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Jean Michel Bidart Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Philippe Chanson Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
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Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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tumor volume was calculated as 0.5×width×length×height ( Lundin & Pedersen 1992 ). After surgery, all the patients were periodically reassessed clinically and radiologically to check for signs and symptoms of disease recurrence. Tumor recurrence was

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Gina Chia-Yi Chu Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of

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Haiyen E Zhau Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of

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Ruoxiang Wang Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of

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André Rogatko Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of

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Xu Feng Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of

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Majd Zayzafoon Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of

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Youhua Liu Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of

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Mary C Farach-Carson Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of

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Sungyong You Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of

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Jayoung Kim Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of

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Michael R Freeman Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of

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Leland W K Chung Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of

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established by our laboratory ( Xu et al . 2006 ) represent stages of human PCa progression. They were maintained in T-medium (Invitrogen) supplemented with 5% FBS. LNCaP and LNCaP Neo/RANKL were maintained in RPMI-1640 supplemented with 10% FBS. RAW264

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Adrian F Daly Department of Endocrinology, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

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Emilie Castermans Department of Human Genetics, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

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Lindsey Oudijk Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands

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Mirtha A Guitelman Division of Endocrinology, Hospital Carlos G. Durand, Buenos Aires, Argentina

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Pablo Beckers Department of Clinical Chemistry, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

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Iulia Potorac Department of Endocrinology, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

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Sebastian J C M M Neggers Department of Endocrinology, Erasmus Medical Center, Rotterdam, The Netherlands

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Nathalie Sacre Department of Human Genetics, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

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Aart-Jan van der Lely Department of Endocrinology, Erasmus Medical Center, Rotterdam, The Netherlands

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Vincent Bours Department of Human Genetics, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

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Wouter W de Herder Department of Endocrinology, Erasmus Medical Center, Rotterdam, The Netherlands

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Albert Beckers Department of Endocrinology, Centre Hospitalier Universitaire de Liège, Liège Université, Liège, Belgium

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prolactinoma was made, and he responded well clinically and biochemically to cabergoline 0.5 mg/week. Eighteen months later, the patient developed malaise, headache, sweating and palpitations with hypertension (133/100 mmHg) and a resting heart rate of 80/min

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Anna Wojcicka Department of Physiology and Cell Biology, Molecular, Genomic Medicine, Laboratory of Human Cancer Genetics, Center for Biostatistics, Cellular and Developmental Biology Graduate Program, The Ohio State University, 1645 Neil Avenue, 304 Hamilton Hall, Columbus, Ohio 43210, USA
Department of Physiology and Cell Biology, Molecular, Genomic Medicine, Laboratory of Human Cancer Genetics, Center for Biostatistics, Cellular and Developmental Biology Graduate Program, The Ohio State University, 1645 Neil Avenue, 304 Hamilton Hall, Columbus, Ohio 43210, USA

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Marta Kotlarek Department of Physiology and Cell Biology, Molecular, Genomic Medicine, Laboratory of Human Cancer Genetics, Center for Biostatistics, Cellular and Developmental Biology Graduate Program, The Ohio State University, 1645 Neil Avenue, 304 Hamilton Hall, Columbus, Ohio 43210, USA

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Xiaoli Zhang Department of Physiology and Cell Biology, Molecular, Genomic Medicine, Laboratory of Human Cancer Genetics, Center for Biostatistics, Cellular and Developmental Biology Graduate Program, The Ohio State University, 1645 Neil Avenue, 304 Hamilton Hall, Columbus, Ohio 43210, USA

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Krystian Jazdzewski Department of Physiology and Cell Biology, Molecular, Genomic Medicine, Laboratory of Human Cancer Genetics, Center for Biostatistics, Cellular and Developmental Biology Graduate Program, The Ohio State University, 1645 Neil Avenue, 304 Hamilton Hall, Columbus, Ohio 43210, USA
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Sissy M Jhiang Department of Physiology and Cell Biology, Molecular, Genomic Medicine, Laboratory of Human Cancer Genetics, Center for Biostatistics, Cellular and Developmental Biology Graduate Program, The Ohio State University, 1645 Neil Avenue, 304 Hamilton Hall, Columbus, Ohio 43210, USA
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). Thus, expression of h NIS is likely to be modulated by miRs. Deregulation of miRs in papillary thyroid carcinomas (PTCs) has been reported by several groups ( He et al . 2005 , Tetzlaff et al . 2007 , Pallante et al . 2010 , de la Chapelle

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Thomas Mussack Endocrine Research Unit, Department of Surgery, Medizinische Klinik und Poliklinik IV, udwig‐Maximilians‐Universität, Ziemssenstraße 1, D-80336 Munich, Germany

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:1 mixture of DMEM and Ham's F-12 medium (DMEM–F12 and supplements, Gibco Invitrogen) at 37 °C in a 5% CO 2 –95% air atmosphere. The medium was supplemented with insulin (10 mg/ml), transferrin (5.5 mg/ml), and selenium (5 ng/ml), l -glutamine (2.5 mm

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Dan L. Duncan Comprehensive Cancer Center, Houston, Texas, USA
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Kimal Rajapakshe Dan L. Duncan Comprehensive Cancer Center, Houston, Texas, USA
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(Biorad). Total protein lysate (40 μg) was loaded into 8.5% polyacrylamide gels or NuPage 4–12% Bis-Tris gels and transferred as previously described ( He et al. 2014 ). Images were acquired using an infrared scanner (Odyssey (LiCoR), Lincoln, NE) and

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He Q 2018 ARMC5 mutations in familial and sporadic primary bilateral macronodular adrenal hyperplasia . PLoS ONE 13 e0191602 . ( https://doi.org/10.1371/journal.pone.0191602 ) Zilbermint M Xekouki P Faucz FR Berthon A Gkourogianni

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