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in the prostate, seminal vesicle, and epididymis ( Thigpen et al. 1992 , Thigpen et al. 1993 ). In a recent study by Dufort and co-workers, 17β-HSD5, which specifically catalyzes the reduction of androstenedione to testosterone, was cloned
Department of Pathology, The Second Xiang-Ya Hospital, Central South University, Changsha, Hunan, People’s Republic of China
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Department of Geriatrics, Institute of Aging and Geriatrics, The Second Xiang-Ya Hospital, Central South University, Changsha, Hunan, People’s Republic of China
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Department of Geriatrics, Institute of Aging and Geriatrics, The Second Xiang-Ya Hospital, Central South University, Changsha, Hunan, People’s Republic of China
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aggressiveness and develop more efficient treatment options. Growing evidence has revealed that the tumour microenvironment (TME), composed of the extracellular matrix and stromal cells, is a complex network, and cancer cells rely on the TME for sustained
Gastrointestinal Unit, Department of Medicine, Cancer Center, Center for Computational and Integrative Biology, Department of Surgery, Department of Pathology, Department of Adult Oncology
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Gastrointestinal Unit, Department of Medicine, Cancer Center, Center for Computational and Integrative Biology, Department of Surgery, Department of Pathology, Department of Adult Oncology
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Gastrointestinal Unit, Department of Medicine, Cancer Center, Center for Computational and Integrative Biology, Department of Surgery, Department of Pathology, Department of Adult Oncology
Gastrointestinal Unit, Department of Medicine, Cancer Center, Center for Computational and Integrative Biology, Department of Surgery, Department of Pathology, Department of Adult Oncology
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Gastrointestinal Unit, Department of Medicine, Cancer Center, Center for Computational and Integrative Biology, Department of Surgery, Department of Pathology, Department of Adult Oncology
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Gastrointestinal Unit, Department of Medicine, Cancer Center, Center for Computational and Integrative Biology, Department of Surgery, Department of Pathology, Department of Adult Oncology
Gastrointestinal Unit, Department of Medicine, Cancer Center, Center for Computational and Integrative Biology, Department of Surgery, Department of Pathology, Department of Adult Oncology
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. Primer sequences and PCR conditions for FEV , adenylate cyclase 2 ( ADCY2 ), nuclear receptor subfamily 4, group A, member 2 ( NR4A2 ), growth arrest and DNA-damage-inducible, beta ( GADD45β ), extracellular matrix protein 1 ( ECM1 ), vesicular monoamine
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concentrations, in conjunction with zinc ions into hexamers ( Emdin et al . 1980 ). This process provides efficient spatial storage within the beta-cell vesicles, but dilution upon exocytosis ensures immediate dissociation into dimers (association of two insulin
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Madrid, Spain
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Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Madrid, Spain
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Instituto de Biomedicina y Biotecnología de Cantabria (IBBTEC), Consejo Superior de Investigaciones Científicas (CSIC), Universidad de Cantabria, Santander, Spain
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Instituto de Biomedicina y Biotecnología de Cantabria (IBBTEC), Consejo Superior de Investigaciones Científicas (CSIC), Universidad de Cantabria, Santander, Spain
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Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Madrid, Spain
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aggressiveness. Although some kinase inhibitors of the ERK (extracellular signal regulated protein kinase) pathway have been approved for the treatment of advanced thyroid carcinomas refractory to radioiodine uptake ( Carneiro et al. 2015 ), the therapeutic
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Veterans Affairs-Northern California Health System, Mather, California, USA
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Department of Urologic Surgery, School of Medicine, University of California Davis, Sacramento, California, USA
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Department of Biomedical Engineering, University of California Davis, Davis, California, USA
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. Osteoblasts build bone by depositing and mineralizing the extracellular matrix The counterpart to the OCL is the OB, the cell responsible for building bone ( Robling 2012 ). Derived from mesenchymal stem cells, cuboidal OBs synthesize and secrete proteins
Obesity Research Institute, Texas Tech University, Lubbock, Texas, USA
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Obesity Research Institute, Texas Tech University, Lubbock, Texas, USA
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Obesity Research Institute, Texas Tech University, Lubbock, Texas, USA
Department of Biological Sciences, Texas Tech University, Lubbock, Texas, USA
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Department of Surgery, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, USA
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Obesity Research Institute, Texas Tech University, Lubbock, Texas, USA
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Obesity Research Institute, Texas Tech University, Lubbock, Texas, USA
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Obesity Research Institute, Texas Tech University, Lubbock, Texas, USA
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invasiveness of both ER− and ER+ BC ( Todorović-Raković & Milovanović 2013 ) as it is associated with other pro-inflammatory cytokines like interleukin-32 (IL-32) to induce extracellular matrix (ECM) remodeling and metastases of in vitro cancer cells
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conditions such as boiling, extended storage, freeze–thawing, and extreme pH levels ( Chen et al . 2008 , Mitchell et al . 2008 ). Emerging evidence indicates that this stability is related to sequestration of extracellular miRNAs in various types of
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profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions . Genome Biology 9 R83 doi:10.1186/gb-2008-9-5-r83 . Bonkhoff H 1996 Role of the basal cells in premalignant
Department of Obstetrics and Gynecology, Department of Pathology and Laboratory Medicine, Jonsson Comprehensive Cancer Center and Broad Center for Regenerative Medicine and Stem Cell Biology, Department of Urology and Anhui Geriatric Institute, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou, Guangdong 510515, People's Republic of China
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Department of Obstetrics and Gynecology, Department of Pathology and Laboratory Medicine, Jonsson Comprehensive Cancer Center and Broad Center for Regenerative Medicine and Stem Cell Biology, Department of Urology and Anhui Geriatric Institute, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou, Guangdong 510515, People's Republic of China
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Department of Obstetrics and Gynecology, Department of Pathology and Laboratory Medicine, Jonsson Comprehensive Cancer Center and Broad Center for Regenerative Medicine and Stem Cell Biology, Department of Urology and Anhui Geriatric Institute, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou, Guangdong 510515, People's Republic of China
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visualized through the expression of GFP-LC3, which upon autophagosome formation becomes clustered on the membrane vesicles and visible as a ring structure under the fluorescent microscope. This analysis as shown in Fig. 3 D demonstrates that there were more