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Laboratory of Molecular Imaging and Therapy, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
Department of Biological Sciences, University of Windsor, Windsor, Ontario, Canada
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Laboratory of Molecular Imaging and Therapy, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
Tumor Microenvironment Global Core Research Center, Seoul National University, Seoul, Korea
Cancer Imaging Center, Seoul National University Hospital, Seoul, Korea
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Department of Pathology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA
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Laboratory of Molecular Imaging and Therapy, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
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Laboratory of Molecular Imaging and Therapy, Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea
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Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK
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Department of Experimental Therapeutics, BC Cancer Research Centre, Vancouver, British Columbia, Canada
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Introduction The main treatment protocol for patients suffering from castration-resistant prostate cancer (CRPC) is androgen receptor pathway inhibition (ARPI). Selection pressure and lineage plasticity of ARPI can lead to neuroendocrine (NE
Department of Urologic Sciences, Vancouver Prostate Centre, University of British Columbia, Vancouver, British Columbia, Canada
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Department of Urology, Xiangya Hospital, Central South University, Changsha, China
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Department of Cardiothoracic Surgeries, Weill Cornell Medical College, Cornell University, New York, New York, USA
Institute for Academic Medicine, Houston Methodist Hospital, Houston, Texas, USA
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Department of Cardiothoracic Surgeries, Weill Cornell Medical College, Cornell University, New York, New York, USA
Institute for Academic Medicine, Houston Methodist Hospital, Houston, Texas, USA
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Department of Cardiothoracic Surgeries, Weill Cornell Medical College, Cornell University, New York, New York, USA
Institute for Academic Medicine, Houston Methodist Hospital, Houston, Texas, USA
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in fully developed prostate in males, and whether HOXA10 regulates signal pathways during prostate cancer (PCa) development or tumor progression into the castrate-resistant stage. PCa is the most commonly diagnosed cancer in males. The primary
School of Nursing, Faculty of Health Sciences and Medicine, West Moreton Hospital and Health Service, Department of Pharmacy, Oncology Pharmacy, Department of Nutrition and Dietetics, Department of Urology, Australian Prostate Cancer Research Centre – Queensland, Department of Diabetes and Endocrinology, School of Medicine, Division of Cancer Services, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
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School of Nursing, Faculty of Health Sciences and Medicine, West Moreton Hospital and Health Service, Department of Pharmacy, Oncology Pharmacy, Department of Nutrition and Dietetics, Department of Urology, Australian Prostate Cancer Research Centre – Queensland, Department of Diabetes and Endocrinology, School of Medicine, Division of Cancer Services, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
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School of Nursing, Faculty of Health Sciences and Medicine, West Moreton Hospital and Health Service, Department of Pharmacy, Oncology Pharmacy, Department of Nutrition and Dietetics, Department of Urology, Australian Prostate Cancer Research Centre – Queensland, Department of Diabetes and Endocrinology, School of Medicine, Division of Cancer Services, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
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School of Nursing, Faculty of Health Sciences and Medicine, West Moreton Hospital and Health Service, Department of Pharmacy, Oncology Pharmacy, Department of Nutrition and Dietetics, Department of Urology, Australian Prostate Cancer Research Centre – Queensland, Department of Diabetes and Endocrinology, School of Medicine, Division of Cancer Services, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
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School of Nursing, Faculty of Health Sciences and Medicine, West Moreton Hospital and Health Service, Department of Pharmacy, Oncology Pharmacy, Department of Nutrition and Dietetics, Department of Urology, Australian Prostate Cancer Research Centre – Queensland, Department of Diabetes and Endocrinology, School of Medicine, Division of Cancer Services, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
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School of Nursing, Faculty of Health Sciences and Medicine, West Moreton Hospital and Health Service, Department of Pharmacy, Oncology Pharmacy, Department of Nutrition and Dietetics, Department of Urology, Australian Prostate Cancer Research Centre – Queensland, Department of Diabetes and Endocrinology, School of Medicine, Division of Cancer Services, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
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School of Nursing, Faculty of Health Sciences and Medicine, West Moreton Hospital and Health Service, Department of Pharmacy, Oncology Pharmacy, Department of Nutrition and Dietetics, Department of Urology, Australian Prostate Cancer Research Centre – Queensland, Department of Diabetes and Endocrinology, School of Medicine, Division of Cancer Services, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
School of Nursing, Faculty of Health Sciences and Medicine, West Moreton Hospital and Health Service, Department of Pharmacy, Oncology Pharmacy, Department of Nutrition and Dietetics, Department of Urology, Australian Prostate Cancer Research Centre – Queensland, Department of Diabetes and Endocrinology, School of Medicine, Division of Cancer Services, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
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Introduction Prostate cancer (PCa) is the second most commonly diagnosed cancer in men after lung cancers. According to the International Agency for Research on Cancer, more than 1.1 million cases were diagnosed in 2012, with highest incidence rates
Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
Department of Prostate Cancer Research
Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
Department of Prostate Cancer Research
Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
Department of Prostate Cancer Research
Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
Department of Prostate Cancer Research
Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
Department of Prostate Cancer Research
Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
Department of Prostate Cancer Research
Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
Department of Prostate Cancer Research
Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
Department of Prostate Cancer Research
Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
Department of Prostate Cancer Research
Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
Department of Prostate Cancer Research
Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
Department of Prostate Cancer Research
Institute of Pathology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Institute for Pathology University Hospital Basel, Basel, Switzerland
Department of Urology St. Claraspital, Basel, Switzerland
Department of Urology University Hospital Basel, Basel, Switzerland
Department of Urology University Hospital of Örebro, Örebro, Sweden
School of Health and Medical Sciences Örebro University, Örebro, Sweden
Center for Genomics and Transcriptomics CeGaT GmbH, Tuebingen, Germany
Clinic for Urology and Pediatric Urology University Hospital of Bonn, Sigmund‐Freud Strasse 25, 53127 Bonn, Germany
Section of Molecular Urooncology Department of Urology, School of Medicine, University of Heidelberg, Heidelberg, Germany
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Introduction Prostate cancer (PCa) is a clinically heterogeneous disease and a leading cause of cancer death worldwide, thus unraveling the molecular basis of this disease is of great importance. Therefore, a notable effort has been made recently by
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Department of Hematology, Department of Experimental Oncology, Oncology and Molecular Medicine, Istituto Superiore Sanità, viale Regina Elena 299, 00161 Rome, Italy
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deregulated in tumours. Prostate cancer: a complex scenario for miR action In developed western countries, prostate cancer is the most common malignant tumour in men, and is the second highest cause of cancer mortality after lung tumours ( Gronberg
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Introduction Prostate cancer develops through a series of defined states: prostatic intraepithelial neoplasia (PIN), high-grade PIN lesions, invasive cancer, and an androgen-independent state ( Scher & Heller 2000 , Culig & Bartsch 2006 , Dehm
Department of Cancer Biology, Kimmel Cancer Center, Departments of Urology, Radiation Oncology, Thomas Jefferson University, 233 South 10th Street, BLSB 1008, Philadelphia, Pennsylvania 19107, USA
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Department of Cancer Biology, Kimmel Cancer Center, Departments of Urology, Radiation Oncology, Thomas Jefferson University, 233 South 10th Street, BLSB 1008, Philadelphia, Pennsylvania 19107, USA
Department of Cancer Biology, Kimmel Cancer Center, Departments of Urology, Radiation Oncology, Thomas Jefferson University, 233 South 10th Street, BLSB 1008, Philadelphia, Pennsylvania 19107, USA
Department of Cancer Biology, Kimmel Cancer Center, Departments of Urology, Radiation Oncology, Thomas Jefferson University, 233 South 10th Street, BLSB 1008, Philadelphia, Pennsylvania 19107, USA
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Introduction Prostate cancer is the second most common cancer in men worldwide ( Ferlay et al . 2010 ). With >90% of prostate cancers initially diagnosed as acinar adenocarcinomas ( Fine 2012 , Humphrey 2012 ), neuroendocrine carcinomas of the
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Introduction Prostate cancer is the most common non-cutaneous malignancy and the second leading cause of cancer deaths among men in the United States (US), with approximately 248,530 new cases and about 34,130 men expected to die of the
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Introduction Prostate cancer is the most frequent malignancy and the second most common cause of cancer-related death in men in the USA and in other countries with a Western lifestyle ( Siegel et al . 2013 ). Almost all prostate cancers are
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Introduction Prostate cancer is the most common solid cancer in males and is the second leading cause of cancer deaths in American men ( Jemal et al . 2008 ). While rates today are markedly higher than rates observed three decades ago, the most