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Manami Inoue Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan

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Shoichiro Tsugane Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan

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esophageal adenocarcinoma, colorectal cancer, pancreatic cancer, postmenopausal breast cancer, endometrial cancer, and kidney cancer. Further, it probably increases the risk of gallbladder cancer, and possibly increases the risk of liver cancer. The WCRF

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-12-0142
Volume/Issue:
Volume 19: Issue 5
Free access
Annu Makker Post Graduate Department of Pathology, King George's Medical University, Lucknow 226003, Uttar Pradesh, India

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Madhu Mati Goel Post Graduate Department of Pathology, King George's Medical University, Lucknow 226003, Uttar Pradesh, India

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Introduction Endometrial cancer (EC) is the most common gynecological malignancy worldwide, with an estimate of more than 288 000 women developing the cancer annually ( Jemal et al . 2011 ). Of significance, the incidence and mortality rates for EC

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-15-0218
Volume/Issue:
Volume 23: Issue 2
Free access
A Tsigginou First Department of Obstetrics and Gynecology, Section on Endocrinology and Genetics (SEGEN), Developmental Endocrinology Branch, Athens University Medical School, Alexandra Hospital, 115 28 Athens, Greece

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E Bimpaki First Department of Obstetrics and Gynecology, Section on Endocrinology and Genetics (SEGEN), Developmental Endocrinology Branch, Athens University Medical School, Alexandra Hospital, 115 28 Athens, Greece

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M Nesterova First Department of Obstetrics and Gynecology, Section on Endocrinology and Genetics (SEGEN), Developmental Endocrinology Branch, Athens University Medical School, Alexandra Hospital, 115 28 Athens, Greece

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A Horvath First Department of Obstetrics and Gynecology, Section on Endocrinology and Genetics (SEGEN), Developmental Endocrinology Branch, Athens University Medical School, Alexandra Hospital, 115 28 Athens, Greece

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S Boikos First Department of Obstetrics and Gynecology, Section on Endocrinology and Genetics (SEGEN), Developmental Endocrinology Branch, Athens University Medical School, Alexandra Hospital, 115 28 Athens, Greece

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C Lyssikatos First Department of Obstetrics and Gynecology, Section on Endocrinology and Genetics (SEGEN), Developmental Endocrinology Branch, Athens University Medical School, Alexandra Hospital, 115 28 Athens, Greece

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C Papageorgiou First Department of Obstetrics and Gynecology, Section on Endocrinology and Genetics (SEGEN), Developmental Endocrinology Branch, Athens University Medical School, Alexandra Hospital, 115 28 Athens, Greece

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C Dimitrakakis First Department of Obstetrics and Gynecology, Section on Endocrinology and Genetics (SEGEN), Developmental Endocrinology Branch, Athens University Medical School, Alexandra Hospital, 115 28 Athens, Greece
First Department of Obstetrics and Gynecology, Section on Endocrinology and Genetics (SEGEN), Developmental Endocrinology Branch, Athens University Medical School, Alexandra Hospital, 115 28 Athens, Greece

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A Rodolakis First Department of Obstetrics and Gynecology, Section on Endocrinology and Genetics (SEGEN), Developmental Endocrinology Branch, Athens University Medical School, Alexandra Hospital, 115 28 Athens, Greece

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C A Stratakis First Department of Obstetrics and Gynecology, Section on Endocrinology and Genetics (SEGEN), Developmental Endocrinology Branch, Athens University Medical School, Alexandra Hospital, 115 28 Athens, Greece

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A Antsaklis First Department of Obstetrics and Gynecology, Section on Endocrinology and Genetics (SEGEN), Developmental Endocrinology Branch, Athens University Medical School, Alexandra Hospital, 115 28 Athens, Greece

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sporadic (not associated with CNC or any other familial tumor syndrome) lesions ( McDaid et al . 1999 , Sandrini et al . 2002 , Bertherat et al . 2003 ). Endometrial cancer is a hormone-dependent lesion. Although there have been no studies to date on

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-11-0328
Volume/Issue:
Volume 19: Issue 4
Free access
Douglas A Gibson MRC Centre for Reproductive Health The University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

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Ioannis Simitsidellis MRC Centre for Reproductive Health The University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

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Frances Collins MRC Centre for Reproductive Health The University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

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Philippa T K Saunders MRC Centre for Reproductive Health The University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK

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Introduction Endometrial cancer (EC) and ovarian cancer are common gynaecological malignancies; however, the impact of androgen action in these cancers is poorly understood. Epidemiological evidence suggests that androgens may be important in the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-13-0551
Volume/Issue:
Volume 21: Issue 4
Free access
Jianguang Ji
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Asta Fôrsti
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Jan Sundquist
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Kari Hemminki
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mothers of twins. A total of 210 women were diagnosed with endometrial cancer after a twin birth. The RR was marginally increased compared with women with a singleton birth (1.08, 95% CI 0.79–1.47). A significant increase was noted for women with the

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-07-0088
Volume/Issue:
Volume 14: Issue 3
Free access
Tim Byers Colorado School of Public Health, Aurora 80045, Colorado, USA

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Rebecca L Sedjo Colorado School of Public Health, Aurora 80045, Colorado, USA

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among women rather than men, which suggests that there may be a predominant early effect mediated by reductions in circulating sex steroid hormone levels. Endometrial cancer The WCRF has estimated that 50% of incident endometrial cancer cases in the

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-14-0580
Volume/Issue:
Volume 22: Issue 3
Free access
S C J P Gielen
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L C M Kühne
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P C Ewing
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L J Blok
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C W Burger
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small (less than 100% endometrium) and one sample was classified by histology as endometrial cancer. From the remaining eight samples RNA was isolated and the quality of RNA was verified. In one of these eight samples the RNA turned out to be degraded

Article Type:
Research Article
DOI:
https://doi.org/10.1677/erc.1.01046
Volume/Issue:
Volume 12: Issue 4
Free access
P Hadji Department of Endocrinology, Reproductive Medicine and Osteoporosis, Philipps-University of Marburg, Baldingerstrasse, 35033 Marburg, Germany

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1983 ). Tamoxifen therapy not only reduced breast cancer recurrence and mortality but was also associated with an increased incidence of thromboembolic events and endometrial cancer, as well as other bothersome AEs, including vaginal discharge, fluid

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-07-0193
Volume/Issue:
Volume 15: Issue 1
Free access
Nicola M Bougen The Liggins Institute, Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, Cancer Science Institute of Singapore and Department of Pharmacology, University of Auckland, 2-6 Park Avenue, Private Bag 92019, Auckland 1023, New Zealand
The Liggins Institute, Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, Cancer Science Institute of Singapore and Department of Pharmacology, University of Auckland, 2-6 Park Avenue, Private Bag 92019, Auckland 1023, New Zealand

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Michael Steiner The Liggins Institute, Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, Cancer Science Institute of Singapore and Department of Pharmacology, University of Auckland, 2-6 Park Avenue, Private Bag 92019, Auckland 1023, New Zealand

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Mikhail Pertziger The Liggins Institute, Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, Cancer Science Institute of Singapore and Department of Pharmacology, University of Auckland, 2-6 Park Avenue, Private Bag 92019, Auckland 1023, New Zealand

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Arindam Banerjee The Liggins Institute, Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, Cancer Science Institute of Singapore and Department of Pharmacology, University of Auckland, 2-6 Park Avenue, Private Bag 92019, Auckland 1023, New Zealand

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Severine E Brunet-Dunand The Liggins Institute, Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, Cancer Science Institute of Singapore and Department of Pharmacology, University of Auckland, 2-6 Park Avenue, Private Bag 92019, Auckland 1023, New Zealand

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Tao Zhu The Liggins Institute, Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, Cancer Science Institute of Singapore and Department of Pharmacology, University of Auckland, 2-6 Park Avenue, Private Bag 92019, Auckland 1023, New Zealand

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Peter E Lobie The Liggins Institute, Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, Cancer Science Institute of Singapore and Department of Pharmacology, University of Auckland, 2-6 Park Avenue, Private Bag 92019, Auckland 1023, New Zealand
The Liggins Institute, Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, Cancer Science Institute of Singapore and Department of Pharmacology, University of Auckland, 2-6 Park Avenue, Private Bag 92019, Auckland 1023, New Zealand

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Jo K Perry The Liggins Institute, Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, Cancer Science Institute of Singapore and Department of Pharmacology, University of Auckland, 2-6 Park Avenue, Private Bag 92019, Auckland 1023, New Zealand

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, risk of cancer compared with individuals from the same family without the receptor deficiency ( Guevara-Aguirre et al . 2011 , Steuerman et al . 2011 ). While studies investigating hGH expression in human breast and endometrial cancer have

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-12-0042
Volume/Issue:
Volume 19: Issue 5
Free access
Oliver Zierau
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Jacintha O’Sullivan
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Colm Morrissey
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Dana McDonald
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Winfried Wünsche
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Martin R Schneider
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Martin P Tenniswood
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Günter Vollmer
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). Recent studies have noted a small but significant increase in the incidence of endometrial cancer in postmenopausal women using hormonal replacement therapy ( Chlebowski et al. 2002 ), and there is also an increased risk of endometrial cancer

Article Type:
Research Article
DOI:
https://doi.org/10.1677/erc.1.00842
Volume/Issue:
Volume 11: Issue 4
Free access