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via androgen-regulated growth factors such as TGFβ1 and insulin-like growth factor 1 (IGF1; Jiang et al . 2011 ). In Fig. 1 , a schematic of androgen-regulated signaling pathways in prostate cancer is shown. CAFs from both the peripheral and
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Department of Animal Biology and Physiology, Biomedical Research Center, Department of Biomedical Sciences, Laboratory of Cytometry, Department of Veterinary Anatomy, Optometry, University of Yaoundé 1, PO Box 812, Yaoundé, Cameroon
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epidermal growth factor . Cancer Research 54 5474 – 5478 . Darago A Sapota A Matych J Nasiadek M Skrzypinska-Gawrysiak M Kilanowicz A 2011 The correlation between zinc and insulin-like growth factor 1 (IGF-1), its binding protein (IGFBP
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integration site 1 gene ( FLI1 ). The resulting EWS-FLI1 fusion protein induces insulin-like growth factor 1 (IGF1) expression and suppresses the expression of insulin-like growth factor-binding protein 3 (IGFBP3) ( Prieur et al . 2004 , France et al . 2011
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growing evidence that thyroid hormones increase the motility of αvβ3-expressing immune cells, and, possibly by similar mechanisms, nerve cell migration ( De Vito et al . 2012 ). An array of growth factors, including PDGF, insulin-like growth factor 1 (IGF
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Departments of Endocrinology and Human Genetics, Clinical Center of Endocrinology and Gerontology, Department of Endocrinology, Assistance Publique‐Hôpitaux de Paris, UMR S1185, INSERM U1185, Servicio de Endocrinología y Nutrición, Section on Endocrinology and Genetics, Division of Endocrinology, Department of Endocrinology, Section of Endocrinology, Section of Endocrinology and Internal Medicine, Servicio de Endocrinología, Service d'endocrinologie‐diabétologie, Murdoch Children's Research Institute, Departments of Internal Medicine and Pediatrics, Departments of Neuroendocrinology and Bone Diseases, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Department of Biotechnological and Applied Clinical Sciences, Neuromed IRCCS, Andrology Department, Endocrinology Clinic, INSERM U1016, Endocrinology Department, Aix‐Marseille Université, Department of Endocrinology, Dipartimento di Medicina Clinica e Chirurgia, Department of Endocrinology, Pediatric Endocrinology Unit, Service D'endocrinologie, Endocrinology, Department of Paediatric Endocrinology, Department of Endocrinology, Laboratory of Molecular Biology, Department of Endocrinology, Centre Hospitalier Universitaire de Liège, University of Liège, Domaine Universitaire du Sart‐Tilman, 4000 Liège, Belgium
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age (>97th percentile, which corresponds to >+2 s.d. ), or a final height >+2 s.d. above the mean for relevant population, associated with elevated GH/insulin-like growth factor 1 (IGF1) and imaging evidence of a pituitary lesion. Details on height
Department of Internal Medicine (DIMI), IRCCS Azienda Ospedaliera Universitaria San Martino – IST Istituto Nazionale per la Ricerca sul Cancro, Department of Experimental, CNR Institute of Organic Synthesis and Photoreactivity (ISOF), CNR Institute of Molecular Bioimaging and Physiology (IBFM), Department of Health Science (DISSAL), University of Genova, Viale Benedetto XV/6, 16132 Genova, Italy
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documented and associated also with decreased plasma concentrations of insulin-like growth factor 1 (IGF1) and insulin ( Pollak 2012 ). Thus, the actions of metformin are not exclusively mediated by inhibition of AMPK ( Watson 2014 ). Indeed, in recent years
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growth factor-1 (IGF-1)-induced uterine responses and in vivo evidence for IGF-1/estrogen receptor cross-talk. Journal of Biological Chemistry 277 8531 –8537. Knowlden JM , Hutcheson IR, Barrow D, Gee JM & Nicholson RI
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-0414 ) Huffman DM Farias Quipildor G Mao K Zhang X Wan J Apontes P Cohen P Barzilai N 2016 Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1
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37°C in a water-saturated atmosphere. Growth factors and inhibitors Stem cell factor (SCF, also known as KIT ligand) was obtained from Cell Signaling Technologies. Recombinant human insulin-like growth factor 1 (IGF1) was from Abcam. ERK
Department of Biotechnological and Applied Clinical Sciences, Department of Neurological Sciences, Endocrinology, CNRS, AP‐HM, Endocrinology and Diabetology Unit, Endocrinology, Department of Neurology and Psychiatry, INSERM, AP‐HM, Department of Radiology, University of L'Aquila, Via Vetoio, Coppito 2, 67100 L'Aquila, Italy
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Department of Biotechnological and Applied Clinical Sciences, Department of Neurological Sciences, Endocrinology, CNRS, AP‐HM, Endocrinology and Diabetology Unit, Endocrinology, Department of Neurology and Psychiatry, INSERM, AP‐HM, Department of Radiology, University of L'Aquila, Via Vetoio, Coppito 2, 67100 L'Aquila, Italy
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Department of Biotechnological and Applied Clinical Sciences, Department of Neurological Sciences, Endocrinology, CNRS, AP‐HM, Endocrinology and Diabetology Unit, Endocrinology, Department of Neurology and Psychiatry, INSERM, AP‐HM, Department of Radiology, University of L'Aquila, Via Vetoio, Coppito 2, 67100 L'Aquila, Italy
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Department of Biotechnological and Applied Clinical Sciences, Department of Neurological Sciences, Endocrinology, CNRS, AP‐HM, Endocrinology and Diabetology Unit, Endocrinology, Department of Neurology and Psychiatry, INSERM, AP‐HM, Department of Radiology, University of L'Aquila, Via Vetoio, Coppito 2, 67100 L'Aquila, Italy
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Department of Biotechnological and Applied Clinical Sciences, Department of Neurological Sciences, Endocrinology, CNRS, AP‐HM, Endocrinology and Diabetology Unit, Endocrinology, Department of Neurology and Psychiatry, INSERM, AP‐HM, Department of Radiology, University of L'Aquila, Via Vetoio, Coppito 2, 67100 L'Aquila, Italy
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, 25 were males and 37 were females, with a mean age of 44.8±12.8 years at surgery (median 44.5 years and range 18–78 years). Patients' clinical, biological and neuroradiological data were recorded. GH, prolactin (PRL) and insulin-like growth factor 1