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Maria Chiara Zatelli Department of Medical Sciences, Section of Endocrinology and Internal Medicine, University of Ferrara, Ferrara, Italy

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Erika Maria Grossrubatscher Endocrine Unit, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy

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Elia Guadagno Department of Advanced Biomedical Sciences, Pathology Section, University of Naples Federico II, Naples, Italy

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Concetta Sciammarella IOS & COLEMAN Srl, Naples, Italy

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Antongiulio Faggiano Thyroid and Parathyroid Surgery Unit, Istituto Nazionale per lo Studio e la Cura Dei Tumori ‘Fondazione G. Pascale’ – IRCCS, Naples, Italy

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Annamaria Colao IOS & COLEMAN Srl, Naples, Italy

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performed in cancer fields different from NENs. Aim The aim of this review is to summarize the available data on two new putative prognostic biomarkers for NENs, such as circulating tumors cells (CTCs) and microRNAs (miRNAs). Methods Among

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-17-0091
Volume/Issue:
Volume 24: Issue 6
Free access
Penn Muluhngwi Department of Biochemistry and Molecular Genetics, Center for Genetics and Molecular Medicine, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA

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Carolyn M Klinge Department of Biochemistry and Molecular Genetics, Center for Genetics and Molecular Medicine, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA

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impetus for understanding ERα's role in driving metastatic disease ( Jordan et al . 2015 ). This review will focus on the role of microRNAs (miRNAs) in acquired endocrine-resistant breast cancer. miRNAs or miRs are small (22 nt), non-protein coding RNAs

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-15-0355
Volume/Issue:
Volume 22: Issue 5
Free access
Sara Jung Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-University, Munich, Germany

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Zoltan Nagy 2nd Department of Medicine, Semmelweis University, Faculty of Medicine, Budapest, Hungary

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Martin Fassnacht Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Würzburg, Würzburg, Germany
Comprehensive Cancer Center Mainfranken, University of Würzburg, Würzburg, Germany

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Gerard Zambetti Department of Pathology, St Jude Children’s Research Hospital, Memphis, Tennessee, USA

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Max Weiss Institute of Pathology, Ludwig-Maximilians-University, Munich, Germany

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Martin Reincke Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-University, Munich, Germany

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Peter Igaz 2nd Department of Medicine, Semmelweis University, Faculty of Medicine, Budapest, Hungary

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Felix Beuschlein Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-University, Munich, Germany

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Constanze Hantel Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-University, Munich, Germany

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the detected differences in therapeutic responsiveness for both tumor models, we studied intratumoral and plasma microRNAs (miRs) as potentially interesting therapeutic biomarkers for ACC. Finally, we provide preliminary clinical data indicating that

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-16-0249
Volume/Issue:
Volume 23: Issue 10
Free access
Stefano Caramuta Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden

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Linkiat Lee Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden

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Deniz M Özata Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden

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Pinar Akçakaya Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden

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Hong Xie Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden

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Anders Höög Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden

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Jan Zedenius Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden

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Martin Bäckdahl Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden

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Catharina Larsson Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden

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Weng-Onn Lui Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden

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the potential of mRNA and microRNA (miRNA) profiling to correctly classify adenomas or carcinomas and to identify subgroups of ACC patients with different survival and outcome ( de Fraipont et al . 2005 , Giordano et al . 2009 , Laurell et al

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-13-0098
Volume/Issue:
Volume 20: Issue 4
Open access
Libero Santarpia Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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George A Calin Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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Liana Adam Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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Lei Ye Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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Alfredo Fusco Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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Serena Giunti Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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Christina Thaller Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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Laura Paladini Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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Xinna Zhang Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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Camilo Jimenez Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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Francesco Trimarchi Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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Adel K El-Naggar Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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Robert F Gagel Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA
Departments of Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics , Urology, Department of Oncology, Department of Pathology, Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Department of Oncology, Department of Gynecologic Oncology, Department of Endocrinology, Department of Pathology, Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

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in the control of the aforementioned functions and intracellular signal transducers are coordinately modified. The cascade of events that leads to metastasis in thyroid cancer, especially MTC, is still poorly understood. MicroRNAs (miRNAs), a class of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-13-0357
Volume/Issue:
Volume 20: Issue 6
Free access
A Karpathakis University College London Cancer Institute, Neuroendocrine Tumour Unit, 72 Huntley Street, London WC1E 6BT, UK
University College London Cancer Institute, Neuroendocrine Tumour Unit, 72 Huntley Street, London WC1E 6BT, UK

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H Dibra University College London Cancer Institute, Neuroendocrine Tumour Unit, 72 Huntley Street, London WC1E 6BT, UK

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C Thirlwell University College London Cancer Institute, Neuroendocrine Tumour Unit, 72 Huntley Street, London WC1E 6BT, UK
University College London Cancer Institute, Neuroendocrine Tumour Unit, 72 Huntley Street, London WC1E 6BT, UK

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phosphorylation; these are catalysed by several enzymes, for example histone acetyltransferases and deacetylases (HDACs). MicroRNAs (miRNAs) are small single-stranded RNA molecules of ∼22 nucleotides in length, which post-transcriptionally regulate gene

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-12-0338
Volume/Issue:
Volume 20: Issue 3
Free access
Robert C Smallridge Division of Endocrinology, Department of Cancer Biology, Department of Internal Medicine

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Laura A Marlow Division of Endocrinology, Department of Cancer Biology, Department of Internal Medicine

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John A Copland Division of Endocrinology, Department of Cancer Biology, Department of Internal Medicine

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gene expression changes in many genes. This high degree of disarray and the rarity of these tumors make it difficult to determine which targets of instability are selected for or convey growth advantages. MicroRNA A new level of the regulation of cell

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-08-0154
Volume/Issue:
Volume 16: Issue 1
Free access
Carla S Verissimo Division of Medical Pharmacology, Department of Human Genetics, Swammerdam Institute for Life Sciences, Leiden/Amsterdam Center for Drug Research, Leiden University Medical Center, Gorlaeus Laboratories, PO Box 9502, 2300 RA Leiden, The Netherlands

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Jan J Molenaar Division of Medical Pharmacology, Department of Human Genetics, Swammerdam Institute for Life Sciences, Leiden/Amsterdam Center for Drug Research, Leiden University Medical Center, Gorlaeus Laboratories, PO Box 9502, 2300 RA Leiden, The Netherlands

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Carlos P Fitzsimons Division of Medical Pharmacology, Department of Human Genetics, Swammerdam Institute for Life Sciences, Leiden/Amsterdam Center for Drug Research, Leiden University Medical Center, Gorlaeus Laboratories, PO Box 9502, 2300 RA Leiden, The Netherlands
Division of Medical Pharmacology, Department of Human Genetics, Swammerdam Institute for Life Sciences, Leiden/Amsterdam Center for Drug Research, Leiden University Medical Center, Gorlaeus Laboratories, PO Box 9502, 2300 RA Leiden, The Netherlands

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Erno Vreugdenhil Division of Medical Pharmacology, Department of Human Genetics, Swammerdam Institute for Life Sciences, Leiden/Amsterdam Center for Drug Research, Leiden University Medical Center, Gorlaeus Laboratories, PO Box 9502, 2300 RA Leiden, The Netherlands

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Wachowiak et al . (2010) Gene symbols and names are in agreement with HUGO Gene Nomenclature Committee even when the nomenclature used in the references is different. Table 3 Potential micro-RNAs as targets for neuroblastoma therapy miRNA Validated target

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-11-0251
Volume/Issue:
Volume 18: Issue 6
Free access
O Chabre Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France

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R Libé Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France

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G Assie Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France

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O Barreau Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France

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J Bertherat Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France

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X Bertagna Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France

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J-J Feige Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France

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N Cherradi Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France
Institut National de la Santé et de la Recherche Médicale, Department of Endocrinology, Commissariat à l'Energie Atomique, Lab. BCI, Paris Descartes University, Centre National de la Recherche Scientifique UMR 8104, Department of Endocrinology, Unité 1036, 17, Rue des Martyrs, F-38054 Grenoble Cedex 09, France

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). MicroRNA (miRNAs) are a family of small non-coding RNA molecules that regulate gene expression at the posttranscriptional level by inducing either degradation of the mRNA transcript or translational repression ( Bartel 2004 ). Alterations of miRNA

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-13-0051
Volume/Issue:
Volume 20: Issue 4
Free access
Tsai-Der Chuang Department of Obstetrics and Gynecology, University of Florida, Gainesville, Florida 32610-0294, USA

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Harekrushna Panda Department of Obstetrics and Gynecology, University of Florida, Gainesville, Florida 32610-0294, USA

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Xiaoping Luo Department of Obstetrics and Gynecology, University of Florida, Gainesville, Florida 32610-0294, USA

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Nasser Chegini Department of Obstetrics and Gynecology, University of Florida, Gainesville, Florida 32610-0294, USA

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regulatory function of microRNAs (miRNAs) on protein-coding gene expression through interacting with their 3′ UTR resulting in their posttranscriptional repression ( Djuranovic et al . 2011 ). Through this mechanism, miRNAs regulate various aspects of normal

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DOI:
https://doi.org/10.1530/ERC-12-0007
Volume/Issue:
Volume 19: Issue 4
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