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Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
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Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
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Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
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German Cancer Consortium (DKTK), partner site Berlin, Berlin, Germany
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Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
German Cancer Consortium (DKTK), partner site Berlin, Berlin, Germany
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Preclinical MRI Center, Charité - Universitätsmedizin Berlin, Berlin, Germany
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Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, and Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Translational Oncology of Solid Tumours, Berlin, Germany
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Department of General, Visceral, and Transplantation Surgery, University Hospital, LMU Munich, Munich, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany
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Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital, University of Zurich (USZ) and University of Zurich (UZH), Zurich, Switzerland
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Centre for Endocrinology, Barts and the London School of Medicine, Queen Mary University of London, United Kingdom
ENETS Centre of Excellence, Royal Free Hospital, London, United Kingdom
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ENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumours of the GastroEnteroPancreatic System at the University Hospital of Munich, Munich, Germany
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Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
German Cancer Consortium (DKTK), partner site Berlin, Berlin, Germany
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Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital, University of Zurich (USZ) and University of Zurich (UZH), Zurich, Switzerland
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and metastatic panNETs ( Yao et al. 2011 , 2016 ), while in neuroendocrine carcinomas (NECs) small studies have reported only modest activity of everolimus ( Panzuto et al. 2017 , Okuyama et al. 2020 ). According to the latest World Health
Department of Urology, Department of Pathology and Laboratory Medicine, Broad Center for Regenerative Medicine and Stem Cell Biology, Transplant Immunology Laboratory, Department of Pathology, Department of Pathology, Department of Pathology, Department of Pathology, The Geriatrics Research Institute, First Affiliated Hospital of Anhui Medical University, Anhui, China
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Department of Urology, Department of Pathology and Laboratory Medicine, Broad Center for Regenerative Medicine and Stem Cell Biology, Transplant Immunology Laboratory, Department of Pathology, Department of Pathology, Department of Pathology, Department of Pathology, The Geriatrics Research Institute, First Affiliated Hospital of Anhui Medical University, Anhui, China
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Department of Urology, Department of Pathology and Laboratory Medicine, Broad Center for Regenerative Medicine and Stem Cell Biology, Transplant Immunology Laboratory, Department of Pathology, Department of Pathology, Department of Pathology, Department of Pathology, The Geriatrics Research Institute, First Affiliated Hospital of Anhui Medical University, Anhui, China
Department of Urology, Department of Pathology and Laboratory Medicine, Broad Center for Regenerative Medicine and Stem Cell Biology, Transplant Immunology Laboratory, Department of Pathology, Department of Pathology, Department of Pathology, Department of Pathology, The Geriatrics Research Institute, First Affiliated Hospital of Anhui Medical University, Anhui, China
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normally quiescent ( Bonkhoff 2001 , Huang et al . 2006 ). While adenocarcinomas comprise the majority of PC, there are variant forms among which small cell neuroendocrine carcinoma (SCNC) is an important histological subtype that is often seen in
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MJ, Tsokos M, Sheahan MD, Nguyen P et al. 1994 Terminal neuroendocrine differentiation of human prostate carcinoma cells in response to increased intracellular cyclic AMP. PNAS 91 5330 –5334. Bjorge JD , Pang A
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carcinoma, pancreatic neuroendocrine tumours, metastatic pheochromocytoma/paraganglioma and parathyroid cancer. To re-energize the workshop concept – greater than 25% of the meeting time was spent in smaller working groups that focused on the important
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years ( Yao et al. 2008 ). Neuroendocrine neoplasms (NENs) are comprised of well-differentiated NETs and poorly differentiated neuroendocrine carcinomas (NECs). The World Health Organization classification reported four categories, based on tumor
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with malignant potential found in familial syndromes of hyperparathyroidism, including 1) HPT-JT-associated parathyroid carcinoma; 2) MEN1-associated nonfunctioning pancreatic neuroendocrine tumors (pNETs), gastrinoma and insulinoma, and thymic and
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Department of Pathology, Department of Pathology, Department of General, Department of Gastroenterology and Endocrinology, Department of Endocrinology, Department of General and Abdominal Surgery, Department of Gastroenterology and Endocrinology, Department of Hepatology and Gastroenterology, Department of Pathology, Institute of Pathology, University of Kiel, Michaelisstr. 11, 24105 Kiel, Germany
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Department of Pathology, Department of Pathology, Department of General, Department of Gastroenterology and Endocrinology, Department of Endocrinology, Department of General and Abdominal Surgery, Department of Gastroenterology and Endocrinology, Department of Hepatology and Gastroenterology, Department of Pathology, Institute of Pathology, University of Kiel, Michaelisstr. 11, 24105 Kiel, Germany
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of uncertain biological behavior (wdNETubs), well-differentiated neuroendocrine carcinomas (wdNECs), or poorly differentiated neuroendocrine carcinomas (pdNECs; Klöppel et al . 2004 ). Proliferative activity was determined by counting Ki-67/MIB-1
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patients with endocrine malignancies, we did not discern a beneficial effect on the course of the disease. Our findings are in keeping with recent reports on the effect of IM in patients with small cell lung carcinoma, a cancer with a related neuroendocrine
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Introduction Medullary thyroid carcinoma (MTC) accounts for 5–10% of all thyroid cancer. Most cases are sporadic but about 25% occur in patients with the multiple endocrine neoplasia type 2 (MEN2) syndrome ( Brauckhoff et al
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Paper Expression Frequency Cases Prognostic relevance of DLK1 Endocrine and neuroendocrine Adrenocortical carcinoma (Hadjidemetriou et al. 2019) Protein IHC 100% 9 (Hadjidemetriou et al. 2019