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Department of Otolaryngology-Head and Neck Surgery-Surgical Oncology, Princess Margaret Cancer Centre/University Health Network, University of Toronto, Toronto, Ontario, Canada
Department of Otolaryngology-Head and Neck Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel
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Department of Otolaryngology-Head and Neck Surgery-Surgical Oncology, Princess Margaret Cancer Centre/University Health Network, University of Toronto, Toronto, Ontario, Canada
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Department of Otolaryngology-Head and Neck Surgery-Surgical Oncology, Princess Margaret Cancer Centre/University Health Network, University of Toronto, Toronto, Ontario, Canada
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Department of Otolaryngology-Head and Neck Surgery-Surgical Oncology, Princess Margaret Cancer Centre/University Health Network, University of Toronto, Toronto, Ontario, Canada
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Department of Otolaryngology-Head and Neck Surgery-Surgical Oncology, Princess Margaret Cancer Centre/University Health Network, University of Toronto, Toronto, Ontario, Canada
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Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
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Department of Otolaryngology-Head and Neck Surgery-Surgical Oncology, Princess Margaret Cancer Centre/University Health Network, University of Toronto, Toronto, Ontario, Canada
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to the minimal amount of tumor cell damage that was observed in the laser control group by both H&E staining and TUNEL assay (8.23% positive, n = 3) ( Fig. 5Ci and Di ), PLP-PDT caused significant tumor tissue damage and apoptosis (TUNEL 66.39 ± 0
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. 2013 ). One single institution study by Kim et al ., including 662 PTC patients, of whom 33 (5%) had LVI, found that there was a significant association between LVI and both lateral cervical lymph node metastases and an increased risk of disease
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Department of Endocrine Surgery, Biostatistics Unit, Department of Endocrinology, King's College Hospital NHS Foundation Trust, King's College London, Denmark Hill, London SE5 9RS, UK
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Villeneuve et al . 2007 11 391 0 0 0 0 0 11 391 Total ( n ) 50 861 394 236 117 26 154 51 788 Percentage of total 98.2 0.8 0.5 0.2 0.1 0.3 100.1 The number of renal transplants indicates the number of
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2014 Blocks to thyroid cancer cell apoptosis can be overcome by inhibition of the MAPK and PI3K/AKT pathways . Cell Death and Disease 5 e1104 . ( doi:10.1038/cddis.2014.78 ) He H Jazdzewski K Li W Liyanarachchi S Nagy R
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excised 22 mm grade 2 pNET with evidence of vascular and perineural invasion. The Ki67 index was 5%. Post-operatively, he required pancreatic enzyme supplementation for exocrine pancreatic insufficiency. Follow-up 12 months post-operatively demonstrated
Department of Pathology, The Second Xiang-Ya Hospital, Central South University, Changsha, Hunan, People’s Republic of China
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Department of Geriatrics, Institute of Aging and Geriatrics, The Second Xiang-Ya Hospital, Central South University, Changsha, Hunan, People’s Republic of China
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Department of Geriatrics, Institute of Aging and Geriatrics, The Second Xiang-Ya Hospital, Central South University, Changsha, Hunan, People’s Republic of China
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. 2014 ). miR-21-5p is one of the most well-studied miRNAs and is implicated in promoting cancer growth and development that is often overexpressed in a wide variety of solid tumour tissues ( Yao et al. 2009 , Au Yeung et al. 2016 ). miR-21’s pro
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well circumscribed and lobulated. The center of the mass showed complex fibrous septae, perhaps outlining the initial primary capsule of the smaller nodule. H&E, 40×. (B) About 5% of the mass showed branching papillae covered by follicular cells with
Department of Anatomic Pathology Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Urology Stanford University School of Medicine, Stanford, California 94305, USA
Taussig Cancer Institute
Stanley Shalom Zielony Institute for Nursing Excellence Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Genetics and Genome Sciences
CASE Comprehensive Cancer Center Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
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Department of Anatomic Pathology Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Urology Stanford University School of Medicine, Stanford, California 94305, USA
Taussig Cancer Institute
Stanley Shalom Zielony Institute for Nursing Excellence Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Genetics and Genome Sciences
CASE Comprehensive Cancer Center Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
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Department of Anatomic Pathology Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Urology Stanford University School of Medicine, Stanford, California 94305, USA
Taussig Cancer Institute
Stanley Shalom Zielony Institute for Nursing Excellence Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Genetics and Genome Sciences
CASE Comprehensive Cancer Center Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
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Department of Anatomic Pathology Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Urology Stanford University School of Medicine, Stanford, California 94305, USA
Taussig Cancer Institute
Stanley Shalom Zielony Institute for Nursing Excellence Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Genetics and Genome Sciences
CASE Comprehensive Cancer Center Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
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Department of Anatomic Pathology Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Urology Stanford University School of Medicine, Stanford, California 94305, USA
Taussig Cancer Institute
Stanley Shalom Zielony Institute for Nursing Excellence Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Genetics and Genome Sciences
CASE Comprehensive Cancer Center Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
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Department of Anatomic Pathology Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Urology Stanford University School of Medicine, Stanford, California 94305, USA
Taussig Cancer Institute
Stanley Shalom Zielony Institute for Nursing Excellence Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Genetics and Genome Sciences
CASE Comprehensive Cancer Center Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
Genomic Medicine Institute
Department of Anatomic Pathology Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Urology Stanford University School of Medicine, Stanford, California 94305, USA
Taussig Cancer Institute
Stanley Shalom Zielony Institute for Nursing Excellence Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Genetics and Genome Sciences
CASE Comprehensive Cancer Center Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
Genomic Medicine Institute
Department of Anatomic Pathology Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Urology Stanford University School of Medicine, Stanford, California 94305, USA
Taussig Cancer Institute
Stanley Shalom Zielony Institute for Nursing Excellence Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Genetics and Genome Sciences
CASE Comprehensive Cancer Center Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
Genomic Medicine Institute
Department of Anatomic Pathology Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Urology Stanford University School of Medicine, Stanford, California 94305, USA
Taussig Cancer Institute
Stanley Shalom Zielony Institute for Nursing Excellence Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Genetics and Genome Sciences
CASE Comprehensive Cancer Center Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
Genomic Medicine Institute
Department of Anatomic Pathology Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Urology Stanford University School of Medicine, Stanford, California 94305, USA
Taussig Cancer Institute
Stanley Shalom Zielony Institute for Nursing Excellence Cleveland Clinic, Cleveland, Ohio 44195, USA
Department of Genetics and Genome Sciences
CASE Comprehensive Cancer Center Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
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stage T2b–T2c tumors, PSA between 10 and 20 ng/ml, or Gleason score 7 ( D'Amico et al . 1998 b ). After radical prostatectomy (RP), 65–80% of patients with IRPC had 5-year relapse-free survival (RFS) ( D'Amico et al . 1998 b , c , d , Meng et al
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The Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel
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with mild autistic disorder at age 5 years and is treated since with Clotiapine 2.5 mg/day. At age 24, he was diagnosed with pituitary micro-adenoma based on elevated prolactin (PRL) levels (2200 IU/L (45–375)), and MRI showing 7 mm pituitary micro
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degradation ( Rhoades et al. 2002 , Tang et al. 2003 , Ambros 2004 , Bartel 2004 ). They are also functional when positioned in a coding region or even in 5′-UTR ( Pillai 2005 ). The miRNA expression pattern is regulated during development and is