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Fidéline Bonnet-Serrano
Fidéline Bonnet-Serrano
Institut Cochin, INSERM U1016, CNRS UMR8104, Paris Descartes University, Paris, France
Hormonal Biology Laboratory, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris, France
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Hormonal Biology Laboratory, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris, France
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Jérôme Bertherat
Jérôme Bertherat
Institut Cochin, INSERM U1016, CNRS UMR8104, Paris Descartes University, Paris, France
Department of Endocrinology, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris, France
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Department of Endocrinology, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris, France
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. 2016 ). Menin function is not well characterized, recent studies suggest interaction with transcription regulating factors like JunD or Smad 3. Lynch syndrome, or hereditary nonpolyposis colorectal cancer (HNPCC) syndrome, is another autosomal
Freya Mertens
Freya Mertens
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Lies Gremeaux
Lies Gremeaux
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Jianghai Chen
Jianghai Chen
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Qiuli Fu
Qiuli Fu
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Christophe Willems
Christophe Willems
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Heleen Roose
Heleen Roose
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Olivier Govaere
Olivier Govaere
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Tania Roskams
Tania Roskams
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Carolina Cristina
Carolina Cristina
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Damasia Becú-Villalobos
Damasia Becú-Villalobos
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Mark Jorissen
Mark Jorissen
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Vincent Vander Poorten
Vincent Vander Poorten
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Marie Bex
Marie Bex
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Johannes van Loon
Johannes van Loon
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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Hugo Vankelecom
Hugo Vankelecom
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
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A MEN1 Multiple endocrine neoplasia 1 D SMAD2 SMAD family member 2 D SMAD3 SMAD family member 3 A SMAD4 SMAD family member 4 D TGFB1 Transforming growth factor, β1 A TGFB2 Transforming growth factor, β2 D TGFBR2 Transforming growth
Antonio De la Vieja
Antonio De la Vieja
Tumor Endocrine Unit, Chronic Disease Program (UFIEC), Instituto de Salud Carlos III, Madrid, Spain
CiberOnc, Instituto de Salud Carlos III, Madrid, Spain
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CiberOnc, Instituto de Salud Carlos III, Madrid, Spain
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Pilar Santisteban
Pilar Santisteban
CiberOnc, Instituto de Salud Carlos III, Madrid, Spain
Department of Physiopathology of Endocrine a Nervous System, Instituto de Investigaciones Biomédicas ‘Alberto Sols’, Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid (CSIC-UAM), Madrid, Spain
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Department of Physiopathology of Endocrine a Nervous System, Instituto de Investigaciones Biomédicas ‘Alberto Sols’, Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid (CSIC-UAM), Madrid, Spain
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upregulated by BRAF-V600E via the TGFβ/Smad3 signaling pathway ( Azouzi et al . 2017 ). Therefore, ROS production by NOX4 participates in the downregulation of thyroid differentiation genes, such as NIS. PI3K downregulates NIS transcription in thyroid
Libero Santarpia
Libero Santarpia
Translational Research Unit, Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics, Department of Oncology, Hospital of Prato and Istituto Toscana Tumori, Piazza dell' Ospedale, 59100 Prato, Italy Departments of
Translational Research Unit, Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics, Department of Oncology, Hospital of Prato and Istituto Toscana Tumori, Piazza dell' Ospedale, 59100 Prato, Italy Departments of
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Translational Research Unit, Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics, Department of Oncology, Hospital of Prato and Istituto Toscana Tumori, Piazza dell' Ospedale, 59100 Prato, Italy Departments of
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Milena Nicoloso
Milena Nicoloso
Translational Research Unit, Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics, Department of Oncology, Hospital of Prato and Istituto Toscana Tumori, Piazza dell' Ospedale, 59100 Prato, Italy Departments of
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George A Calin
George A Calin
Translational Research Unit, Endocrine Neoplasia and Hormonal Disorders, Experimental Therapeutics, Department of Oncology, Hospital of Prato and Istituto Toscana Tumori, Piazza dell' Ospedale, 59100 Prato, Italy Departments of
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2 could be regulated by HMGA2, and that the regulation of Snail promoter by HMGA2 involves binding of this factor to Smad3 and Smad4 ( Thuault et al . 2008 ). In addition, RAS, which is another target of let-7 and a driving force for EMT, has
Annu Makker
Annu Makker
Post Graduate Department of Pathology, King George's Medical University, Lucknow 226003, Uttar Pradesh, India
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Madhu Mati Goel
Madhu Mati Goel
Post Graduate Department of Pathology, King George's Medical University, Lucknow 226003, Uttar Pradesh, India
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its effect through heterotrimeric complex of transmembrane serine/threonine kinase, the type I (RI) and type II (RII) receptors. Following ligand binding, RI phosphorylates Smad2 and Smad3 (R-Smads). Phosphorylated R-Smads form a complex with Smad4 and
