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, Tavangar et al . 2007 ), no ER immunoreactivity was observed in other studies ( Jaklic et al . 1995 , Arain et al . 2003 ). These widely varying results were described for both papillary carcinoma and follicular thyroid carcinoma (FTC) samples. The
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CEA, Department of Nuclear Medicine and Endocrine Oncology, Inserm, Institut Gustave Roussy, Université Paris XI, INSERM ERI-21, University of Nice-Sophia Antipolis, Laboratory of Clinical and Experimental Pathology and CHU-CRLCC-UNSA Tumour/Tissue Bank of Nice Area, Department of Otorhinolaryngology, Institut Curie, CNRS, Université Paris VI, DSV, IRCM, LCE, BP6, Fontenay-aux-Roses F-92265, France
CEA, Department of Nuclear Medicine and Endocrine Oncology, Inserm, Institut Gustave Roussy, Université Paris XI, INSERM ERI-21, University of Nice-Sophia Antipolis, Laboratory of Clinical and Experimental Pathology and CHU-CRLCC-UNSA Tumour/Tissue Bank of Nice Area, Department of Otorhinolaryngology, Institut Curie, CNRS, Université Paris VI, DSV, IRCM, LCE, BP6, Fontenay-aux-Roses F-92265, France
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CEA, Department of Nuclear Medicine and Endocrine Oncology, Inserm, Institut Gustave Roussy, Université Paris XI, INSERM ERI-21, University of Nice-Sophia Antipolis, Laboratory of Clinical and Experimental Pathology and CHU-CRLCC-UNSA Tumour/Tissue Bank of Nice Area, Department of Otorhinolaryngology, Institut Curie, CNRS, Université Paris VI, DSV, IRCM, LCE, BP6, Fontenay-aux-Roses F-92265, France
CEA, Department of Nuclear Medicine and Endocrine Oncology, Inserm, Institut Gustave Roussy, Université Paris XI, INSERM ERI-21, University of Nice-Sophia Antipolis, Laboratory of Clinical and Experimental Pathology and CHU-CRLCC-UNSA Tumour/Tissue Bank of Nice Area, Department of Otorhinolaryngology, Institut Curie, CNRS, Université Paris VI, DSV, IRCM, LCE, BP6, Fontenay-aux-Roses F-92265, France
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CEA, Department of Nuclear Medicine and Endocrine Oncology, Inserm, Institut Gustave Roussy, Université Paris XI, INSERM ERI-21, University of Nice-Sophia Antipolis, Laboratory of Clinical and Experimental Pathology and CHU-CRLCC-UNSA Tumour/Tissue Bank of Nice Area, Department of Otorhinolaryngology, Institut Curie, CNRS, Université Paris VI, DSV, IRCM, LCE, BP6, Fontenay-aux-Roses F-92265, France
CEA, Department of Nuclear Medicine and Endocrine Oncology, Inserm, Institut Gustave Roussy, Université Paris XI, INSERM ERI-21, University of Nice-Sophia Antipolis, Laboratory of Clinical and Experimental Pathology and CHU-CRLCC-UNSA Tumour/Tissue Bank of Nice Area, Department of Otorhinolaryngology, Institut Curie, CNRS, Université Paris VI, DSV, IRCM, LCE, BP6, Fontenay-aux-Roses F-92265, France
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CEA, Department of Nuclear Medicine and Endocrine Oncology, Inserm, Institut Gustave Roussy, Université Paris XI, INSERM ERI-21, University of Nice-Sophia Antipolis, Laboratory of Clinical and Experimental Pathology and CHU-CRLCC-UNSA Tumour/Tissue Bank of Nice Area, Department of Otorhinolaryngology, Institut Curie, CNRS, Université Paris VI, DSV, IRCM, LCE, BP6, Fontenay-aux-Roses F-92265, France
CEA, Department of Nuclear Medicine and Endocrine Oncology, Inserm, Institut Gustave Roussy, Université Paris XI, INSERM ERI-21, University of Nice-Sophia Antipolis, Laboratory of Clinical and Experimental Pathology and CHU-CRLCC-UNSA Tumour/Tissue Bank of Nice Area, Department of Otorhinolaryngology, Institut Curie, CNRS, Université Paris VI, DSV, IRCM, LCE, BP6, Fontenay-aux-Roses F-92265, France
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to the routine screening of thyroid nodules using neck ultrasound and fine needle biopsy, which permit the detection of small papillary carcinomas that would otherwise have gone undetected ( Leenhardt et al . 2004 , Colonna et al . 2007 ). This
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) and patients with the noninvasive encapsulated follicular variant of papillary carcinoma (E-FVPTC; Rosario et al . 2014 a ), who clearly would not benefit from ablation with 131 I, were excluded. Patients with one of the following characteristics
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Serviço de Endocrinologia, Faculdade de Ciências Médicas da Universidade Nova de Lisboa, Faculdade de Medicina de Lisboa, Centro de Investigação de Patobiologia Molecular (CIPM) and
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Kimura ET Gandhi M Biddinger PW Knauf JA Basolo F Zhu Z Giannini R Salvatore G Fusco A 2003 BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas arising from papillary
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Section of Pediatric Surgery, Finnish Cancer Registry, Tampere School of Health Sciences, Helsinki Medical Imaging Center, Department of Pathology, Section of Pediatrics, Program of Molecular Neurology, The Estonian Genome Center, Hospital for Children and Adolescents, University of Helsinki, Stenbäckinkatu 11, PL 281, FI-00029 HUS Helsinki, Finland
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Section of Pediatric Surgery, Finnish Cancer Registry, Tampere School of Health Sciences, Helsinki Medical Imaging Center, Department of Pathology, Section of Pediatrics, Program of Molecular Neurology, The Estonian Genome Center, Hospital for Children and Adolescents, University of Helsinki, Stenbäckinkatu 11, PL 281, FI-00029 HUS Helsinki, Finland
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Section of Pediatric Surgery, Finnish Cancer Registry, Tampere School of Health Sciences, Helsinki Medical Imaging Center, Department of Pathology, Section of Pediatrics, Program of Molecular Neurology, The Estonian Genome Center, Hospital for Children and Adolescents, University of Helsinki, Stenbäckinkatu 11, PL 281, FI-00029 HUS Helsinki, Finland
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had undetectable serum calcitonin levels and they underwent two to three repeated US examinations confirming benign and unprogressive nature of the lesions. The patient with papillary carcinoma underwent uncomplicated thyroid lobectomy at the age of 46
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Department of Pathology, Department of Pathology, Laboratory of Environmental Mutagenesis and Carcinogenesis, Department of Medical Oncology, Department of Medicine, Institute of Pathology, Memorial Sloan-Kettering Cancer Center, School of Medicine, Aristotle University of Thessaloniki, University Campus, Thessaloniki 54006, Greece
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Department of Pathology, Department of Pathology, Laboratory of Environmental Mutagenesis and Carcinogenesis, Department of Medical Oncology, Department of Medicine, Institute of Pathology, Memorial Sloan-Kettering Cancer Center, School of Medicine, Aristotle University of Thessaloniki, University Campus, Thessaloniki 54006, Greece
Department of Pathology, Department of Pathology, Laboratory of Environmental Mutagenesis and Carcinogenesis, Department of Medical Oncology, Department of Medicine, Institute of Pathology, Memorial Sloan-Kettering Cancer Center, School of Medicine, Aristotle University of Thessaloniki, University Campus, Thessaloniki 54006, Greece
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. Nikiforova MN Kimura ET Gandhi M Biddinger PW Knauf JA Basolo F Zhu Z Giannini R Salvatore G Fusco A 2003 BRAF mutations in thyroid tumors are restricted to papillary carcinomas and anaplastic or poorly differentiated carcinomas
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JV 1986 Familial papillary carcinoma of the thyroid . American Journal of Medical Genetics 25 775 – 782 . Sturgeon C Clark OH 2005 Familial nonmedullary thyroid cancer . Thyroid 15 588 – 593 . Triponez F Wong M Sturgeon C
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DL Fidler JP Giordano TJ Biddinger PW Nikiforov YE 2006 Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas . American Journal of
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2004 Molecular profiling distinguishes papillary carcinoma from benign thyroid nodules . Journal of Clinical Endocrinology and Metabolism 89 3214 – 3223 . Franzen A Heldin NE 2001 BMP-7-induced cell cycle arrest of anaplastic thyroid
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et al . 2007 ). In addition, Hilly et al . (2013) have recently demonstrated that DC density in papillary carcinoma is correlated with the concurrent thyroiditis grade and DC density in the surrounding areas of thyroiditis. These data suggest that