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Claudia Lanari Instituto de Biología y Medicina Experimental (IBYME‐CONICET), Oral and Pharyngeal Cancer Branch, Buenos Aires, Argentina

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Victoria Wargon Instituto de Biología y Medicina Experimental (IBYME‐CONICET), Oral and Pharyngeal Cancer Branch, Buenos Aires, Argentina

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Paola Rojas Instituto de Biología y Medicina Experimental (IBYME‐CONICET), Oral and Pharyngeal Cancer Branch, Buenos Aires, Argentina

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Alfredo A Molinolo Instituto de Biología y Medicina Experimental (IBYME‐CONICET), Oral and Pharyngeal Cancer Branch, Buenos Aires, Argentina

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Introduction Breast cancer is the most frequently diagnosed malignant neoplasia and is a leading cause of cancer death in females worldwide. Breast cancer ranks second overall in cancer mortality (10.9%) and accounts for 23% (1.38 million) of new

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-11-0378
Volume/Issue:
Volume 19: Issue 3
Free access
Matthew J Schiewer Kimmel Cancer Center, Cancer Biology, Urology, Radiation Oncology, Departments of
Kimmel Cancer Center, Cancer Biology, Urology, Radiation Oncology, Departments of

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Robert Den Kimmel Cancer Center, Cancer Biology, Urology, Radiation Oncology, Departments of

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David T Hoang Kimmel Cancer Center, Cancer Biology, Urology, Radiation Oncology, Departments of
Kimmel Cancer Center, Cancer Biology, Urology, Radiation Oncology, Departments of

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Michael A Augello Kimmel Cancer Center, Cancer Biology, Urology, Radiation Oncology, Departments of
Kimmel Cancer Center, Cancer Biology, Urology, Radiation Oncology, Departments of

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Yaacov R Lawrence Kimmel Cancer Center, Cancer Biology, Urology, Radiation Oncology, Departments of

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Adam P Dicker Kimmel Cancer Center, Cancer Biology, Urology, Radiation Oncology, Departments of

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Karen E Knudsen Kimmel Cancer Center, Cancer Biology, Urology, Radiation Oncology, Departments of
Kimmel Cancer Center, Cancer Biology, Urology, Radiation Oncology, Departments of
Kimmel Cancer Center, Cancer Biology, Urology, Radiation Oncology, Departments of
Kimmel Cancer Center, Cancer Biology, Urology, Radiation Oncology, Departments of

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Introduction Prostate cancer (PCa) is the most frequently diagnosed non-cutaneous malignancy and the second leading cause of death due to cancer in men in the United States ( Jemal et al . 2010 ). Treatment options for localized disease include

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-11-0072
Volume/Issue:
Volume 19: Issue 1
Open access
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Michael G Apps Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales 2006, Australia

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Eugene H Y Choi Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales 2006, Australia

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Nial J Wheate Faculty of Pharmacy, The University of Sydney, Sydney, New South Wales 2006, Australia

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platinum drug ( Wheate et al . 2010 ). Platinum drugs are used to treat a wide variety of cancers, including some endocrine-related cancers: testicular and ovarian carcinomas. They are also used to treat melanoma, small-cell and non-small-cell lung cancer

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-15-0237
Volume/Issue:
Volume 22: Issue 4
Free access
T Frogne Department of Tumor Endocrinology, Institute of Cancer Biology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen, Denmark

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J S Jepsen Department of Tumor Endocrinology, Institute of Cancer Biology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen, Denmark

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S S Larsen Department of Tumor Endocrinology, Institute of Cancer Biology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen, Denmark

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C K Fog Department of Tumor Endocrinology, Institute of Cancer Biology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen, Denmark

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B L Brockdorff Department of Tumor Endocrinology, Institute of Cancer Biology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen, Denmark

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A E Lykkesfeldt Department of Tumor Endocrinology, Institute of Cancer Biology, Danish Cancer Society, Strandboulevarden 49, DK-2100 Copenhagen, Denmark

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Introduction The antiestrogen tamoxifen has been first-line endocrine therapy for estrogen receptor (ER) positive breast cancer patients for more than 25 years, and several other antiestrogens and selective ER modulators (SERMs) have

Article Type:
Research Article
DOI:
https://doi.org/10.1677/erc.1.00946
Volume/Issue:
Volume 12: Issue 3
Free access
Bin Zhao The Second Affiliated Hospital & Yuying Children’s Hospital, Wenzhou Medical University, Wenzhou, China

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Hong Zhao The Third Affiliated Hospital of Harbin Medical University, Harbin, China

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Jiaxin Zhao The Second Affiliated Hospital & Yuying Children’s Hospital, Wenzhou Medical University, Wenzhou, China
The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China

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Introduction Approximately 20% patients with breast cancer (BC) have HER2-positive disease. These patients are often associated with a highly aggressive tumor behavior and poor outcomes ( Slamon et al . 1987 ). Therefore, HER2 has become an

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-18-0029
Volume/Issue:
Volume 25: Issue 6
Free access
Carles Zafon Diabetes and Metabolism Research Unit (VHIR) and Department of Endocrinology, University Hospital Vall d’Hebron and Autonomous University of Barcelona, Barcelona, Spain
Consortium for the Study of Thyroid Cancer (CECaT), Catalonia, Spain

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Joan Gil Program of Predictive and Personalized Medicine of Cancer, Germans Trias i Pujol Research Institute (PMPPC-IGTP), Barcelona, Spain

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Beatriz Pérez-González Program of Predictive and Personalized Medicine of Cancer, Germans Trias i Pujol Research Institute (PMPPC-IGTP), Barcelona, Spain

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Mireia Jordà Consortium for the Study of Thyroid Cancer (CECaT), Catalonia, Spain
Program of Predictive and Personalized Medicine of Cancer, Germans Trias i Pujol Research Institute (PMPPC-IGTP), Barcelona, Spain

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Introduction Thyroid cancer, the most prevalent endocrine malignancy, covers the full range of phenotypes from indolent to the worst forms of human cancer. It is categorized into differentiated thyroid cancer (DTC), poorly differentiated

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-19-0093
Volume/Issue:
Volume 26: Issue 7
Free access
Marjory Alana Marcello Laboratory of Cancer Molecular Genetics (Gemoca), Faculty of Medical Sciences, University of Campinas (FCM- Unicamp), Rua Tessália Vieira de Camargo 126, Barão Geraldo, Campinas, São Paulo 13083-970, Brazil

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Lucas Leite Cunha Laboratory of Cancer Molecular Genetics (Gemoca), Faculty of Medical Sciences, University of Campinas (FCM- Unicamp), Rua Tessália Vieira de Camargo 126, Barão Geraldo, Campinas, São Paulo 13083-970, Brazil

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Fernando Assis Batista Laboratory of Cancer Molecular Genetics (Gemoca), Faculty of Medical Sciences, University of Campinas (FCM- Unicamp), Rua Tessália Vieira de Camargo 126, Barão Geraldo, Campinas, São Paulo 13083-970, Brazil

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Laura Sterian Ward Laboratory of Cancer Molecular Genetics (Gemoca), Faculty of Medical Sciences, University of Campinas (FCM- Unicamp), Rua Tessália Vieira de Camargo 126, Barão Geraldo, Campinas, São Paulo 13083-970, Brazil

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Introduction Overweight and/or obesity have been consistently related to the development and progression of different types of cancers during the last decades. An extensive review published a few years ago estimated that approximately 20% of all

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-14-0070
Volume/Issue:
Volume 21: Issue 5
Free access
L Hilakivi-Clarke Lombardi Comprehensive Cancer Center, Department of Oncology, 3970 Reservoir Road NW, Box 571468, Washington DC 20057-1468, USA

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C Wang Lombardi Comprehensive Cancer Center, Department of Oncology, 3970 Reservoir Road NW, Box 571468, Washington DC 20057-1468, USA

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M Kalil Lombardi Comprehensive Cancer Center, Department of Oncology, 3970 Reservoir Road NW, Box 571468, Washington DC 20057-1468, USA

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R Riggins Lombardi Comprehensive Cancer Center, Department of Oncology, 3970 Reservoir Road NW, Box 571468, Washington DC 20057-1468, USA

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R G Pestell Lombardi Comprehensive Cancer Center, Department of Oncology, 3970 Reservoir Road NW, Box 571468, Washington DC 20057-1468, USA

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Introduction Breast cancer accounts for approximately 30% of all cancers diagnosed in women in the USA. As the second leading cause of cancer death in women, breast cancer accounts for approximately 15% of all female cancer deaths

Article Type:
Review Article
DOI:
https://doi.org/10.1677/erc.1.00665
Volume/Issue:
Volume 11: Issue 4
Free access
Simon Linder Division of Oncogenomics, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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Henk G van der Poel Division of Urology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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Andries M Bergman Division of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
Division of Oncogenomics, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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Wilbert Zwart Division of Oncogenomics, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands
Laboratory of Chemical Biology and Institute for Complex Molecular Systems, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands

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Stefan Prekovic Division of Oncogenomics, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands

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Introduction Ever since the discovery that prostate cancer (PCa) growth after androgen deprivation therapy (ADT) remains dependent on androgen receptor (AR) signaling, researchers have been looking for new effective ways to block the action of

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-18-0289
Volume/Issue:
Volume 26: Issue 1
Open access
Anastasia Alataki Ralph Lauren Centre for Breast Cancer Research, Royal Marsden Hospital and The Institute of Cancer Research, London, UK
The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK

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Mitch Dowsett Ralph Lauren Centre for Breast Cancer Research, Royal Marsden Hospital and The Institute of Cancer Research, London, UK
The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, UK

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Introduction Breast cancer development and progression are significantly affected by signalling pathways involving oestrogen receptor (ER) and growth factor receptors ( Arpino et al. 2008 ). Over 80% of all breast cancer cases are deemed ER

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-21-0293
Volume/Issue:
Volume 29: Issue 8
Open access