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Department of Medical Genetics, Lady Davis Institute Jewish General Hospital, McGill University, Department Endocrinology and Diabetes, Lady Cilento Children's Hospital, School of Medicine, University of Queensland, Queensland Children's Medical Research Institute, Department of Histopathology, King Edward Memorial Hospital, John Hunter Children's Hospital, School of Medicine and Public Health, Hunter Medical Research Institute, University of Newcastle, School of Paediatrics and Child Health, University of Western Australia, Department of Paediatric Endocrinology and Diabetes, Princess Margaret Hospital for Children, Child and Adolescent Health Service, Genetics and Epigenetics in Health and Disease Genetics and Genomic Medicine Programme UCL Institute of Child Health Great Ormond Street Hospital for Children, The Scripps Research Institute, Departments of Oncology and Experimental Medicine, McGill University, Program in Cancer Genetics, Departments of Oncology and Human Genetics, McGill University, Montréal, Quebec, Canada
Department of Medical Genetics, Lady Davis Institute Jewish General Hospital, McGill University, Department Endocrinology and Diabetes, Lady Cilento Children's Hospital, School of Medicine, University of Queensland, Queensland Children's Medical Research Institute, Department of Histopathology, King Edward Memorial Hospital, John Hunter Children's Hospital, School of Medicine and Public Health, Hunter Medical Research Institute, University of Newcastle, School of Paediatrics and Child Health, University of Western Australia, Department of Paediatric Endocrinology and Diabetes, Princess Margaret Hospital for Children, Child and Adolescent Health Service, Genetics and Epigenetics in Health and Disease Genetics and Genomic Medicine Programme UCL Institute of Child Health Great Ormond Street Hospital for Children, The Scripps Research Institute, Departments of Oncology and Experimental Medicine, McGill University, Program in Cancer Genetics, Departments of Oncology and Human Genetics, McGill University, Montréal, Quebec, Canada
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Department of Medical Genetics, Lady Davis Institute Jewish General Hospital, McGill University, Department Endocrinology and Diabetes, Lady Cilento Children's Hospital, School of Medicine, University of Queensland, Queensland Children's Medical Research Institute, Department of Histopathology, King Edward Memorial Hospital, John Hunter Children's Hospital, School of Medicine and Public Health, Hunter Medical Research Institute, University of Newcastle, School of Paediatrics and Child Health, University of Western Australia, Department of Paediatric Endocrinology and Diabetes, Princess Margaret Hospital for Children, Child and Adolescent Health Service, Genetics and Epigenetics in Health and Disease Genetics and Genomic Medicine Programme UCL Institute of Child Health Great Ormond Street Hospital for Children, The Scripps Research Institute, Departments of Oncology and Experimental Medicine, McGill University, Program in Cancer Genetics, Departments of Oncology and Human Genetics, McGill University, Montréal, Quebec, Canada
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Department of Medical Genetics, Lady Davis Institute Jewish General Hospital, McGill University, Department Endocrinology and Diabetes, Lady Cilento Children's Hospital, School of Medicine, University of Queensland, Queensland Children's Medical Research Institute, Department of Histopathology, King Edward Memorial Hospital, John Hunter Children's Hospital, School of Medicine and Public Health, Hunter Medical Research Institute, University of Newcastle, School of Paediatrics and Child Health, University of Western Australia, Department of Paediatric Endocrinology and Diabetes, Princess Margaret Hospital for Children, Child and Adolescent Health Service, Genetics and Epigenetics in Health and Disease Genetics and Genomic Medicine Programme UCL Institute of Child Health Great Ormond Street Hospital for Children, The Scripps Research Institute, Departments of Oncology and Experimental Medicine, McGill University, Program in Cancer Genetics, Departments of Oncology and Human Genetics, McGill University, Montréal, Quebec, Canada
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Department of Medical Genetics, Lady Davis Institute Jewish General Hospital, McGill University, Department Endocrinology and Diabetes, Lady Cilento Children's Hospital, School of Medicine, University of Queensland, Queensland Children's Medical Research Institute, Department of Histopathology, King Edward Memorial Hospital, John Hunter Children's Hospital, School of Medicine and Public Health, Hunter Medical Research Institute, University of Newcastle, School of Paediatrics and Child Health, University of Western Australia, Department of Paediatric Endocrinology and Diabetes, Princess Margaret Hospital for Children, Child and Adolescent Health Service, Genetics and Epigenetics in Health and Disease Genetics and Genomic Medicine Programme UCL Institute of Child Health Great Ormond Street Hospital for Children, The Scripps Research Institute, Departments of Oncology and Experimental Medicine, McGill University, Program in Cancer Genetics, Departments of Oncology and Human Genetics, McGill University, Montréal, Quebec, Canada
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B and C). The best described function of DICER1 protein is to remove the terminal loop from pre-miRNA to produce mature microRNAs (miRNAs). Mature miRNAs are called 5p miRNAs if they originate from the 5 prime end or 3p miRNAs if they originate from
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Perren A Moch H Komminoth P Nikiforov YE Nikiforova MN 2013 Comprehensive MicroRNA expression profiling identifies novel markers in follicular variant of papillary thyroid carcinoma . Thyroid 23 1383 – 1389 . ( doi:10.1089/thy
Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland
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Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland
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profiles will be the basis for better indication of specific epigenetic modifiers for future specific treatments. MicroRNA (miRNA) expression profiles Pancreatic NET There are only few studies investigating the effect of microRNAs (miRNA) in
Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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Cancer Genetics Laboratory, Department of Endocrinology, Department of Surgery, Department of Anatomical Pathology, Cancer Diagnosis and Oncology Group, Department of Endocrine and Oncology Surgery, Neurogenetics Research Laboratory, Department of ENT Surgery, Department of Neurology, Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research
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hypoxic rather than a kinase activation phenotype. There has been increasing interest in the role of microRNA (miRNA) in tumour development. These non-coding RNAs, 20–22 nucleotides in length, regulate gene expression via binding to 3′UTRs of their related
Department of Plant Pathology and Microbiology, National Taiwan University, Taipei, Taiwan
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D Yang TL Bucay N Sekhon K Majid S Shahryari V Dahiya R Tanaka Y Saini S 2018 microRNA-1246 is an exosomal biomarker for aggressive prostate cancer . Cancer Research 78 1833 – 1844 . ( https://doi.org/10.1158/0008-5472.CAN-17
Maimonides Institute for Biomedical Research of Cordoba (IMIBIC); Reina Sofia University Hospital, Córdoba, Spain
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’, ‘germline’, ‘somatic’, ‘alternative lengthening of telomeres’, ‘whole-genome sequencing’, ‘chromatin remodeling’, ‘DNA repair’, ‘cell-free DNA’, ‘RNA markers’, ‘microRNAs’, ‘somatostatin receptor expression’, ‘O-6-methylguanine-DNA methyltransferase’, ‘mTOR
School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, New South Wales, Australia
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School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, University of Newcastle, New South Wales, Australia
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School of Medicine and Public Health, Faculty of Health and Medicine, University of Newcastle, New South Wales, Australia
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HGSOC-specific microRNAs, DNA methylation and histone acetylation patterns. Figure 3 The role of DNA repair deficiencies in high-grade serous ovarian cancer (HGSOC) platinum chemotherapy resistance. (A) NER-and HR-proficient (NER+ and HR
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Genomics Research Centre, Institute of Health and Biomedical Innovation, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia
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its profound metastatic and invasive characteristics ( Guo et al . 2014 ). Therefore, this study investigated the simultaneous suppression of angiogenesis, proliferation and invasion of this aggressive tumour through microRNA expression, which could
Department of Pathology, The Second Xiang-Ya Hospital, Central South University, Changsha, Hunan, People’s Republic of China
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Department of Geriatrics, Institute of Aging and Geriatrics, The Second Xiang-Ya Hospital, Central South University, Changsha, Hunan, People’s Republic of China
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Department of Geriatrics, Institute of Aging and Geriatrics, The Second Xiang-Ya Hospital, Central South University, Changsha, Hunan, People’s Republic of China
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their exosomes . Oncogene 34 3640 – 3650 . ( https://doi.org/10.1038/onc.2014.300 ) 10.1038/onc.2014.300 25263437 Cui RR Li SJ Liu LJ Yi L Liang QH Zhu X Liu GY Liu Y Wu SS Liao XB , et al . 2012 MicroRNA-204 regulates vascular smooth muscle
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−ΔΔCt ) method and normalized against the threshold cycle (Ct) of GAPDH or β-actin. For detecting expression levels of miRNA, cDNA samples were amplified using TaqMan MicroRNA Assays (Applied Biosystems), and RNU6B was used as a reference gene