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Sophie Moog PARCC, INSERM UMR970, Equipe Labellisée par la Ligue contre le Cancer, Paris, France
Université de Paris, Paris, France

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Charlotte Lussey-Lepoutre PARCC, INSERM UMR970, Equipe Labellisée par la Ligue contre le Cancer, Paris, France
Department of Nuclear Medicine, Sorbonne University, Pitie-Salpetriere Hospital, Paris, France

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Judith Favier PARCC, INSERM UMR970, Equipe Labellisée par la Ligue contre le Cancer, Paris, France
Université de Paris, Paris, France

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-0113 ) Bayley JP Kunst HP Cascon A Sampietro ML Gaal J Korpershoek E Hinojar-Gutierrez A Timmers HJ Hoefsloot LH Hermsen MA 2010 SDHAF2 mutations in familial and sporadic paraganglioma and phaeochromocytoma . Lancet: Oncology 11 366

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Simona Grozinsky-Glasberg Barts and the London School of Medicine, Institute of Endocrinology, Centre for Endocrinology, University of London, London EC1M 6BQ, UK
Barts and the London School of Medicine, Institute of Endocrinology, Centre for Endocrinology, University of London, London EC1M 6BQ, UK

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Ilan Shimon Barts and the London School of Medicine, Institute of Endocrinology, Centre for Endocrinology, University of London, London EC1M 6BQ, UK

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Márta Korbonits Barts and the London School of Medicine, Institute of Endocrinology, Centre for Endocrinology, University of London, London EC1M 6BQ, UK

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Ashley B Grossman Barts and the London School of Medicine, Institute of Endocrinology, Centre for Endocrinology, University of London, London EC1M 6BQ, UK

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to the intraoperative use in patients with carcinoid associated right-sided heart failure ( Watson et al . 1990 , Vergani et al . 1998 ). Phaeochromocytomas and paragangliomas arise from chromaffin cells and may occur in sporadic or familial forms

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Brian Harding
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Manuel C Lemos
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Anita A C Reed
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Gerard V Walls
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Jeshmi Jeyabalan
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Michael R Bowl
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Hilda Tateossian Academic Endocrine Unit, Mammalian Genetics Unit and Mary Lyon Centre, Department of Neuropathology, Unit of Clinical Biochemistry, Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, University of Oxford, Headington, Oxford OX3 7LJ, UK

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Nicky Sullivan Academic Endocrine Unit, Mammalian Genetics Unit and Mary Lyon Centre, Department of Neuropathology, Unit of Clinical Biochemistry, Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, University of Oxford, Headington, Oxford OX3 7LJ, UK

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Tertius Hough Academic Endocrine Unit, Mammalian Genetics Unit and Mary Lyon Centre, Department of Neuropathology, Unit of Clinical Biochemistry, Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, University of Oxford, Headington, Oxford OX3 7LJ, UK

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William D Fraser Academic Endocrine Unit, Mammalian Genetics Unit and Mary Lyon Centre, Department of Neuropathology, Unit of Clinical Biochemistry, Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, University of Oxford, Headington, Oxford OX3 7LJ, UK

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Olaf Ansorge Academic Endocrine Unit, Mammalian Genetics Unit and Mary Lyon Centre, Department of Neuropathology, Unit of Clinical Biochemistry, Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, University of Oxford, Headington, Oxford OX3 7LJ, UK

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Michael T Cheeseman Academic Endocrine Unit, Mammalian Genetics Unit and Mary Lyon Centre, Department of Neuropathology, Unit of Clinical Biochemistry, Nuffield Department of Clinical Medicine, Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, University of Oxford, Headington, Oxford OX3 7LJ, UK

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Rajesh V Thakker
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-associated tumours, e.g. phaeochromocytomas, thyroid tumours and gonadal tumours ( Table 1 ). The basis for these differences remain to be elucidated; however, it is interesting to note that in two of the conventional Men1 +/− models, exon 2 which contains

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David Taïeb Department of Nuclear Medicine, La Timone University Hospital, CERIMED, Aix-Marseille University, Marseille, France

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Abhishek Jha Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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Giorgio Treglia Clinic of Nuclear Medicine and PET/CT Center, Ente Ospedaliero Cantonale, Bellinzona, Switzerland
Department of Nuclear Medicine and Molecular Imaging, Lausanne University Hospital, Lausanne, Switzerland
Health Technology Assessment Unit, General Directorate, Ente Ospedaliero Cantonale, Bellinzona, Switzerland

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Karel Pacak Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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phaeochromocytoma . Endocrine-Related Cancer 97 – 111. ( https://doi.org/10.1677/ERC-10-0211 ) Estevao R Duarte H Lopes F Fernandes J Monteiro E 2015 Peptide receptor radionuclide therapy in head and neck paragangliomas - Report of 14 cases

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Robin Schürfeld Division of Endocrinology and Diabetes, Department of Internal Medicine, University of Leipzig, Leipzig, Germany

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Christina Pamporaki TU Dresden, Medical Clinic III, University Hospital Carl Gustav Carus, Dresden, Germany

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Mirko Peitzsch TU Dresden, Institute of Clinical Chemistry and Laboratory Medicine, Dresden, Germany

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Nada Rayes Center of Surgery, Division of Endocrine Surgery, Department for Visceral, Transplant, Thoracic, and Vascular Surgery, University of Leipzig, Leipzig, Germany

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Osama Sabri Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany

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Silvio Rohm Center of Surgery, Department for Visceral, Transplant, Thoracic, and Vascular Surgery, University of Leipzig, Leipzig, Germany
Center of Surgery, Department for Vascular Surgery, Diakonissen Hospital of Leipzig, Leipzig, Germany

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Ronald Biemann Institute of Clinical Chemistry and Laboratory Medicine, University of Leipzig, Leipzig, Germany

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Benjamin Sandner Division of Endocrinology and Diabetes, Department of Internal Medicine, University of Leipzig, Leipzig, Germany

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Anke Tönjes Division of Endocrinology and Diabetes, Department of Internal Medicine, University of Leipzig, Leipzig, Germany

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Graeme Eisenhofer TU Dresden, Medical Clinic III, University Hospital Carl Gustav Carus, Dresden, Germany

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, et al. 2014 Biochemical diagnosis of phaeochromocytoma using plasma-free normetanephrine, metanephrine and methoxytyramine: importance of supine sampling under fasting conditions . Clinical Endocrinology 80 478 – 486 . ( https://doi.org/10.1111/cen

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Roland Därr Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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Joan Nambuba Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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Jaydira Del Rivero Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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Ingo Janssen Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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Maria Merino Laboratory of Pathology, National Institutes of Health, Bethesda, Maryland, USA

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Milena Todorovic Institute of Hematology, Clinical Center of Serbia and Medical Faculty University of Belgrade, Belgrade, Serbia

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Bela Balint Institute of Transfusiology and Hemobiology of Military Medical Academy and Institute for Medical Research, University of Belgrade, Belgrade, Serbia

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Ivana Jochmanova Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA
1st Department of Internal Medicine, Faculty of Medicine, Pavol Jozef Safarik University in Kosice, Kosice, Slovakia

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Josef T Prchal Division of Hematology, University of Utah, Salt Lake City, Utah, USA

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Ronald M Lechan Tupper Research Institute and Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Tufts Medical Center, Boston, Massachusetts, USA

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Arthur S Tischler Department of Pathology and Laboratory Medicine, Tufts Medical Center, Boston, Massachusetts, USA

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Vera Popovic Institute of Endocrinology, Clinical Center of Serbia, Medical Faculty, University Belgrade, Belgrade, Serbia

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Dragana Miljic Institute of Endocrinology, Clinical Center of Serbia, Medical Faculty, University Belgrade, Belgrade, Serbia

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Karen T Adams Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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F Ryan Prall Department of Ophthalmology, Eugene and Marilyn Glick Eye Institute, Indiana University School of Medicine, Indianapolis, Indiana, USA

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Alexander Ling Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA

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Meredith R Golomb Division of Child Neurology, Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, USA

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Michael Ferguson Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana, USA

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Naris Nilubol Endocrine Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

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Clara C Chen Division of Nuclear Medicine, Department of Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA

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Emily Chew Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA

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David Taïeb Department of Nuclear Medicine, La Timone University Hospital & CERIMED & Inserm UMR1068 Marseille Cancerology Research Center, Institut Paoli-Calmettes, Aix-Marseille University, Marseille, France

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Constantine A Stratakis Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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Tito Fojo Medical Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

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Chunzhang Yang Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

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Electron Kebebew Endocrine Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

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Zhengping Zhuang Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

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Karel Pacak Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA

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metabolomic and secretory phenotypes in phaeochromocytoma . Endocrine-Related Cancer 18 97 – 111 . ( doi:10.1677/ERC-10-0211 ) Favier J Buffet A Gimenez-Roqueplo AP 2012 HIF2A mutations in paraganglioma with polycythemia . New England

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B Havekes Department of Endocrinology and Metabolic Diseases, Center of Human and Clinical Genetics, Department of Otorhinolaryngology, Department of Surgery, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands

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A A van der Klaauw Department of Endocrinology and Metabolic Diseases, Center of Human and Clinical Genetics, Department of Otorhinolaryngology, Department of Surgery, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands

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M M Weiss Department of Endocrinology and Metabolic Diseases, Center of Human and Clinical Genetics, Department of Otorhinolaryngology, Department of Surgery, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands

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J C Jansen Department of Endocrinology and Metabolic Diseases, Center of Human and Clinical Genetics, Department of Otorhinolaryngology, Department of Surgery, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands

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A G L van der Mey Department of Endocrinology and Metabolic Diseases, Center of Human and Clinical Genetics, Department of Otorhinolaryngology, Department of Surgery, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands

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A H J T Vriends Department of Endocrinology and Metabolic Diseases, Center of Human and Clinical Genetics, Department of Otorhinolaryngology, Department of Surgery, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands

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B A Bonsing Department of Endocrinology and Metabolic Diseases, Center of Human and Clinical Genetics, Department of Otorhinolaryngology, Department of Surgery, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands

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J A Romijn Department of Endocrinology and Metabolic Diseases, Center of Human and Clinical Genetics, Department of Otorhinolaryngology, Department of Surgery, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands

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E P M Corssmit Department of Endocrinology and Metabolic Diseases, Center of Human and Clinical Genetics, Department of Otorhinolaryngology, Department of Surgery, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands

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gene, in hereditary paraganglioma . Science 287 848 – 851 . Benn DE Robinson BG 2006 Genetic basis of phaeochromocytoma and paraganglioma . Best Practice and Research. Clinical Endocrinology and Metabolism 20 435 – 450 . Benn DE

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Adrian F Daly Department of Endocrinology Centre Hospitalier Universitaire de Liège, University of Liège, Domaine Universitaire du Sart‐Tilman, 4000 Liège, Belgium

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Albert Beckers Department of Endocrinology Centre Hospitalier Universitaire de Liège, University of Liège, Domaine Universitaire du Sart‐Tilman, 4000 Liège, Belgium

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Dannenberg H 2009 An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis . Lancet Oncology 10 764 – 771 . ( doi:10

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Lucie Evenepoel Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium
Human Molecular Genetics, de Duve Institute, Université catholique de Louvain, Brussels, Belgium

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Raphaël Helaers Human Molecular Genetics, de Duve Institute, Université catholique de Louvain, Brussels, Belgium

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Laurent Vroonen Department of Endocrinology, Centre Hospitalier Universitaire de Liège, University of Liège, Domaine Universitaire du Sart-Tilman, Liège, Belgium

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Selda Aydin Pathology Department, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

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Marc Hamoir Otolaryngology Department, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

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Dominique Maiter Endocrinology Department, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

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Miikka Vikkula Human Molecular Genetics, de Duve Institute, Université catholique de Louvain, Brussels, Belgium

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Alexandre Persu Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium
Cardiology Department, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

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.ajhg.2015.11.011 Luchetti A Walsh D Rodger F Clark G Martin T Irving R Sanna M Yao M Robledo M Neumann HP 2015 Profiling of somatic mutations in phaeochromocytoma and paraganglioma by targeted next generation sequencing analysis . International

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L Fishbein Division of Endocrinology, Metabolism and Diabetes and Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado School of Medicine, University of Colorado Cancer Center, Aurora, Colorado, USA

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S Ben-Maimon Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Renal and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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S Keefe Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Division of Medical Oncology and Hematology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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K Cengel Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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D A Pryma Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Division of Nuclear Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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A Loaiza-Bonilla Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Division of Medical Oncology and Hematology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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D L Fraker Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Division of Endocrine Oncologic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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K L Nathanson Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Division of Translational Medicine and Human Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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D L Cohen Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Renal and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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phaeochromocytoma: systematic review and meta-analysis . Clinical Endocrinology 80 487 – 501 . ( doi:10.1111/cen.12341 ) 10.1111/cen.12341 24118038 Vogel J Atanacio AS Prodanov T Turkbey BI Adams K Martucci V Camphausen K Fojo

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