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Chiara Verdelli Laboratory of Experimental Endocrinology, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy

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Irene Forno Department of Pathophysiology and Organ Transplantation, University of Milan, Milan, Italy

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Annamaria Morotti Department of Pathophysiology and Organ Transplantation, University of Milan, Milan, Italy
Endocrine Surgery, IRCCS Ospedale San Raffaele, Milan, Italy

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Riccardo Maggiore Endocrine Surgery, IRCCS Istituto Auxologico Italiano, Milan, Italy

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Gilberto Mari Endocrine Surgery, IRCCS Istituto Auxologico Italiano, Milan, Italy

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Leonardo Vicentini Division of Pathology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

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Stefano Ferrero Endocrine Surgery, IRCCS Ospedale San Raffaele, Milan, Italy
Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy

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Elisabetta Kuhn Endocrine Surgery, IRCCS Ospedale San Raffaele, Milan, Italy
Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy

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Valentina Vaira Department of Pathophysiology and Organ Transplantation, University of Milan, Milan, Italy
Division of Pathology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

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Sabrina Corbetta Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy
Endocrinology and Diabetology Service, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy

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parathyroid tumors include miRNAs involved in angiogenesis. In particular, previous reports described that miR-126-3p and miR-126-5p were reduced in parathyroid carcinomas compared with adenomas, while they did not consider miR-126-3p expression in normal

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-20-0313
Volume/Issue:
Volume 28: Issue 1
Restricted access
Päivi Järvensivu Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology and Turku Center for Disease Modeling, University of Turku, Turku, Finland

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Taija Heinosalo Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology and Turku Center for Disease Modeling, University of Turku, Turku, Finland

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Janne Hakkarainen Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology and Turku Center for Disease Modeling, University of Turku, Turku, Finland

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Pauliina Kronqvist Institute of Biomedicine, Research Center for Cancer, Infections and Immunity, University of Turku and Department of Pathology, Turku University Hospital, Turku, Finland

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Niina Saarinen Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology and Turku Center for Disease Modeling, University of Turku, Turku, Finland

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Matti Poutanen Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology and Turku Center for Disease Modeling, University of Turku, Turku, Finland

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determined in 4-month-old HSD17B1TG and WT females. Radioactive [ 3 H]-E1 (Perkin Elmer) dissolved in ethanol:saline (20:80 by vol.) was slowly injected i.v. (2.5 μL/g, 1.6 Mbq/mouse). Mice were terminally anesthetized with tribromoethanol (Avertin, 600

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-17-0476
Volume/Issue:
Volume 25: Issue 4
Free access
Andrew G Gianoukakis Los Angeles Biomedical Research Institute and Division of Endocrinology and Metabolism, Department of Medicine at Harbor-UCLA Medical Center, Torrance, California, USA
David Geffen School of Medicine, University of California – Los Angeles, Los Angeles, California, USA

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Corina E Dutcus Eisai Inc., Woodcliff Lake, New Jersey, USA

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Nicolas Batty Eisai Inc., Woodcliff Lake, New Jersey, USA

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Matthew Guo Eisai Inc., Woodcliff Lake, New Jersey, USA

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Mahadi Baig Eisai Inc., Woodcliff Lake, New Jersey, USA

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with greater disease burden (tumor size ≤35 mm: 44.3 months; 35–60 mm: 27.5 months; 60–92 mm: 18.0 months; >92 mm: 15.7 months), patients with liver metastasis (yes: 15.7 months; no: 30.5 months) and patients with brain metastasis (yes: 9.3 months; no

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-18-0049
Volume/Issue:
Volume 25: Issue 6
Open access
Andres Elía Instituto de Biología y Medicina Experimental (IBYME), CONICET, Argentina

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Leo Saldain Instituto de Biología y Medicina Experimental (IBYME), CONICET, Argentina

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Silvia Lovisi Hospital de Agudos “Magdalena V de Martínez”, General Pacheco, Argentina

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Paula Martínez Vazquez Hospital de Agudos “Magdalena V de Martínez”, General Pacheco, Argentina

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Javier Burruchaga Hospital de Agudos “Magdalena V de Martínez”, General Pacheco, Argentina

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Caroline A Lamb Instituto de Biología y Medicina Experimental (IBYME), CONICET, Argentina

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Isabel Alicia Lüthy Instituto de Biología y Medicina Experimental (IBYME), CONICET, Argentina

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Federico Diez University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, UK

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Natalie Z M Homer University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, UK

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Ruth Andrew University/BHF Centre for Cardiovascular Science, Queen's Medical Research Institute, University of Edinburgh, UK

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Paola Rojas Instituto de Biología y Medicina Experimental (IBYME), CONICET, Argentina

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Claudia Lanari Instituto de Biología y Medicina Experimental (IBYME), CONICET, Argentina

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15 mm, (iii) PRA/PRB ratios higher than 1.5 determined by Western blot, (iv) PR total levels ≥50% evaluated by immunohistochemistry, (v) World Health Organization condition of 1 with the adequate function of organs and systems: absolute neutrophil

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-23-0238
Volume/Issue:
Volume 31: Issue 2
Open access
Nicola Tufton Department of Endocrinology, St Bartholomew’s Hospital, Barts Health NHS Trust, West Smithfield, London, UK
Centre for Endocrinology, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK

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Rahul Ghelani Department of Endocrinology, Royal Free Hospital, Hampstead, London, UK

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Umasuthan Srirangalingam Department of Endocrinology, Royal Free Hospital, Hampstead, London, UK

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Ajith V Kumar North East Thames Regional Genetics Service, Great Ormond Street Hospital, London, UK

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William M Drake Department of Endocrinology, St Bartholomew’s Hospital, Barts Health NHS Trust, West Smithfield, London, UK
Department of Endocrinology, Southampton General Hospital, University Hospital Southampton NHS Trust, Southampton, Hampshire, UK

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Donato Iacovazzo Department of Endocrinology, Southampton General Hospital, University Hospital Southampton NHS Trust, Southampton, Hampshire, UK

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Kassiani Skordilis Department of Histopathology, Queen Elizabeth Hospital, University Hospital Birmingham NHS Foundation Trust, Birmingham, UK

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Daniel Berney Department of Histopathology, St Bartholomew’s Hospital, Barts Health NHS Trust, West Smithfield, London, UK

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Ma’en Al-Mrayat Department of Endocrinology, Southampton General Hospital, University Hospital Southampton NHS Trust, Southampton, Hampshire, UK

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Bernard Khoo Department of Endocrinology, Royal Free Hospital, Hampstead, London, UK

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Scott A Akker Department of Endocrinology, St Bartholomew’s Hospital, Barts Health NHS Trust, West Smithfield, London, UK

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a 5 cm para-adrenal PGL, which was subsequently resected. He developed a symptomatic recurrence one year later, which was surgically resected. Eight years after his original diagnosis, he presented with symptoms of catecholamine excess and four new

Article Type:
Letter
DOI:
https://doi.org/10.1530/ERC-17-0030
Volume/Issue:
Volume 24: Issue 7
Free access
Kiyoshi Ito Department of Disaster Obstetrics and Gynecology, International Research Institute of Disaster Science (IRIDeS), Tohoku University, Sendai, Japan
Department of Disaster Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan

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Yasuhiro Miki Department of Disaster Obstetrics and Gynecology, International Research Institute of Disaster Science (IRIDeS), Tohoku University, Sendai, Japan

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Takashi Suzuki Department of Pathology and Histotechnology, Tohoku University Graduate School of Medicine, Sendai, Japan

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Keely May McNamara Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan

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Hironobu Sasano Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan

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), androstenedione (A4), testosterone and 5α-dihydrotestosterone (DHT), were significantly associated with an increased risk of developing endometrial carcinoma ( Potischman et al . 1996 , Kaaks et al . 2002 , Lukanova et al . 2004 , Allen et al . 2008

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-15-0470
Volume/Issue:
Volume 23: Issue 7
Free access
Toyoshi Endo Third Department of Internal Medicine, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo City, Yamanashi 409-3898, Japan

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Tetsuro Kobayashi Third Department of Internal Medicine, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Chuo City, Yamanashi 409-3898, Japan

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-stimulating hormone (TSH; Nikiforov & Nikiforova 2011 ). The RET/PTC rearrangement and the BRAF V600E point mutation are the two most common genetic alterations associated with PTCs; the prevalence of RET/PTC varies from 2.5 to 78% ( Zou et al . 1994

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-13-0310
Volume/Issue:
Volume 20: Issue 6
Open access
Katarina Edfeldt Departments of Surgical Sciences, Medical Sciences, Uppsala University Hospital, Uppsala University, Entrance 70, 3 tr, SE-75185 Uppsala, Sweden

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Tanveer Ahmad Departments of Surgical Sciences, Medical Sciences, Uppsala University Hospital, Uppsala University, Entrance 70, 3 tr, SE-75185 Uppsala, Sweden

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Göran Åkerström Departments of Surgical Sciences, Medical Sciences, Uppsala University Hospital, Uppsala University, Entrance 70, 3 tr, SE-75185 Uppsala, Sweden

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Eva Tiensuu Janson Departments of Surgical Sciences, Medical Sciences, Uppsala University Hospital, Uppsala University, Entrance 70, 3 tr, SE-75185 Uppsala, Sweden

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Per Hellman Departments of Surgical Sciences, Medical Sciences, Uppsala University Hospital, Uppsala University, Entrance 70, 3 tr, SE-75185 Uppsala, Sweden

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Peter Stålberg Departments of Surgical Sciences, Medical Sciences, Uppsala University Hospital, Uppsala University, Entrance 70, 3 tr, SE-75185 Uppsala, Sweden

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Peyman Björklund Departments of Surgical Sciences, Medical Sciences, Uppsala University Hospital, Uppsala University, Entrance 70, 3 tr, SE-75185 Uppsala, Sweden

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Gunnar Westin Departments of Surgical Sciences, Medical Sciences, Uppsala University Hospital, Uppsala University, Entrance 70, 3 tr, SE-75185 Uppsala, Sweden

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are increasing. The tumors are small (often <2 cm) and slow growing (Ki67 proliferation index is often <2%), but still have a lethal outcome with a 5-year survival rate around 65% ( Yao et al . 2008 , Norlen et al . 2012 ). Many patients have tumor

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-13-0419
Volume/Issue:
Volume 21: Issue 2
Free access
Sílvia F Sousa Department of Oral Surgery and Pathology, Department of Pathology, Section on Endocrinology and Genetics, João de Barros Barreto University Hospital, School of Dentistry

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Ricardo S Gomez Department of Oral Surgery and Pathology, Department of Pathology, Section on Endocrinology and Genetics, João de Barros Barreto University Hospital, School of Dentistry

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Marina G Diniz Department of Oral Surgery and Pathology, Department of Pathology, Section on Endocrinology and Genetics, João de Barros Barreto University Hospital, School of Dentistry

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Vanessa F Bernardes Department of Oral Surgery and Pathology, Department of Pathology, Section on Endocrinology and Genetics, João de Barros Barreto University Hospital, School of Dentistry

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Flávia F C Soares Department of Oral Surgery and Pathology, Department of Pathology, Section on Endocrinology and Genetics, João de Barros Barreto University Hospital, School of Dentistry

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João Artur R Brito Department of Oral Surgery and Pathology, Department of Pathology, Section on Endocrinology and Genetics, João de Barros Barreto University Hospital, School of Dentistry

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Sophie Liu Department of Oral Surgery and Pathology, Department of Pathology, Section on Endocrinology and Genetics, João de Barros Barreto University Hospital, School of Dentistry

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Hélder Antônio R Pontes Department of Oral Surgery and Pathology, Department of Pathology, Section on Endocrinology and Genetics, João de Barros Barreto University Hospital, School of Dentistry

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Constantine A Stratakis Department of Oral Surgery and Pathology, Department of Pathology, Section on Endocrinology and Genetics, João de Barros Barreto University Hospital, School of Dentistry

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Carolina C Gomes Department of Oral Surgery and Pathology, Department of Pathology, Section on Endocrinology and Genetics, João de Barros Barreto University Hospital, School of Dentistry

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after all of the skin had been removed and they had been fixed in 4% paraformaldehyde (PFA). Bony structures were slowly decalcified with EDTA 0.9 M at pH 7.5 over a period of 20 days, rinsed with distilled water, sectioned, paraffin embedded, and H&E

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-15-0094
Volume/Issue:
Volume 22: Issue 3
Free access
Irasema Mendieta Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México

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Gabriel Rodríguez-Gómez Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México

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Bertha Rueda-Zarazúa Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México

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Julia Rodríguez-Castelán Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México

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Winniberg Álvarez-León Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México

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Evangelina Delgado-González Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México

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Brenda Anguiano Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México

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Olivia Vázquez-Martínez Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México

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Mauricio Díaz-Muñoz Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México

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Carmen Aceves Instituto de Neurobiología, UNAM-Juriquilla, Querétaro, México

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of the highest purity grade commercially available. Cell culture The NB cell lines SH-SY5Y (CRL-2266), SK-N-BE(2) (CRL-2271), and SK-N-AS (CRL-2137) were obtained from American Type Culture Collection (ATCC), passage 1–5, and recently tested

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-20-0354
Volume/Issue:
Volume 27: Issue 12
Restricted access