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Marjory Alana Marcello Laboratory of Cancer Molecular Genetics (Gemoca), Faculty of Medical Sciences, University of Campinas (FCM- Unicamp), Rua Tessália Vieira de Camargo 126, Barão Geraldo, Campinas, São Paulo 13083-970, Brazil

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Lucas Leite Cunha Laboratory of Cancer Molecular Genetics (Gemoca), Faculty of Medical Sciences, University of Campinas (FCM- Unicamp), Rua Tessália Vieira de Camargo 126, Barão Geraldo, Campinas, São Paulo 13083-970, Brazil

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Fernando Assis Batista Laboratory of Cancer Molecular Genetics (Gemoca), Faculty of Medical Sciences, University of Campinas (FCM- Unicamp), Rua Tessália Vieira de Camargo 126, Barão Geraldo, Campinas, São Paulo 13083-970, Brazil

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Laura Sterian Ward Laboratory of Cancer Molecular Genetics (Gemoca), Faculty of Medical Sciences, University of Campinas (FCM- Unicamp), Rua Tessália Vieira de Camargo 126, Barão Geraldo, Campinas, São Paulo 13083-970, Brazil

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, endometrial cancer, colon cancer, esophageal adenocarcinoma, kidney cancer, liver cancer, pancreatic cancer, prostate cancer, thyroid cancers, leukemia, non-Hodgkin lymphoma, and myeloma are related to overweight and obesity with respect to development

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Xi Zhang Shenzhen Bay Laboratory, Shenzhen, P R China

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Vijay Pandey Tsinghua Berkeley Shenzhen Institute and Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, P R China

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Vipul Bhardwaj Tsinghua Berkeley Shenzhen Institute and Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, P R China

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Tao Zhu Shenzhen Bay Laboratory, Shenzhen, P R China
Department of Oncology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, P R China
The CAS Key Laboratory of Innate Immunity and Chronic Disease, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, P R China

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Peter E Lobie Shenzhen Bay Laboratory, Shenzhen, P R China
Tsinghua Berkeley Shenzhen Institute and Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, P R China

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histopathological samples ( Wu et al. 2011 , Zhang et al. 2015 ). Also, hGH expression, albeit at low levels, has been observed in triple-negative breast cancer cell lines ( Chen et al. 2015 ), in endometrial ( Pandey et al. 2008 , Bougen et al. 2011

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S E Bojesen
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S K Kjær
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E V S Høgdall
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B L Thomsen
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C K Høgdall
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J Blaakær
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A Tybjærg-Hansen
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B G Nordestgaard
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, Pantazis K, Constantinides TC, Kotsis A & Bontis I 2004 P53 codon 72 polymorphism and correlation with ovarian and endometrial cancer in Greek women. European Journal of Cancer Prevention 13 277 –280. Agoulnik IU , Tong XW

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Yu-Feng Tian
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Chi-Hong Chu
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Mei-Hsuan Wu
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Chia-Lin Chang
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Tsan Yang
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Yu-Ching Chou
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Giu-Cheng Hsu
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Cheng-Ping Yu
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Jyh-Cherng Yu
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Chien-An Sun
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is a protein hormone secreted exclusively by adipocytes ( Chandran et al. 2003 ), and circulating adiponectin levels are inversely associated with the risk of obesity-related malignancies, including endometrial cancer ( Petridou et al. 2003 , Dal

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M Wijnen Department of Pediatric Oncology/Hematology, Erasmus MC – Sophia Children’s Hospital, Rotterdam, the Netherlands
Department of Medicine, Section Endocrinology, Erasmus University Medical Center, Rotterdam, the Netherlands

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M M van den Heuvel-Eibrink Department of Pediatric Oncology/Hematology, Erasmus MC – Sophia Children’s Hospital, Rotterdam, the Netherlands
Princess Maxima Center for Pediatric Oncology, Utrecht, the Netherlands

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M Medici Department of Medicine, Section Endocrinology, Erasmus University Medical Center, Rotterdam, the Netherlands
Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, the Netherlands

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R P Peeters Department of Medicine, Section Endocrinology, Erasmus University Medical Center, Rotterdam, the Netherlands
Rotterdam Thyroid Center, Erasmus University Medical Center, Rotterdam, the Netherlands

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A J van der Lely Department of Medicine, Section Endocrinology, Erasmus University Medical Center, Rotterdam, the Netherlands

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S J C M M Neggers Department of Pediatric Oncology/Hematology, Erasmus MC – Sophia Children’s Hospital, Rotterdam, the Netherlands
Department of Medicine, Section Endocrinology, Erasmus University Medical Center, Rotterdam, the Netherlands

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, nonmedullary thyroid cancer, endometrial cancer, genitourinary tumors Pilarski & Nagy (2012) , Shiovitz & Korde (2015) Li–Fraumeni syndrome (LFS) TP53 Breast cancer, sarcoma, brain tumor, ­adrenocortical tumor, leukemia, lung cancer Shiovitz

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Sefirin Djiogue Department of Animal Biology and Physiology, Biomedical Research Center, Department of Biomedical Sciences, Laboratory of Cytometry, Department of Veterinary Anatomy, Optometry, University of Yaoundé 1, PO Box 812, Yaoundé, Cameroon

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Armel Hervé Nwabo Kamdje Department of Animal Biology and Physiology, Biomedical Research Center, Department of Biomedical Sciences, Laboratory of Cytometry, Department of Veterinary Anatomy, Optometry, University of Yaoundé 1, PO Box 812, Yaoundé, Cameroon
Department of Animal Biology and Physiology, Biomedical Research Center, Department of Biomedical Sciences, Laboratory of Cytometry, Department of Veterinary Anatomy, Optometry, University of Yaoundé 1, PO Box 812, Yaoundé, Cameroon

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Lorella Vecchio Department of Animal Biology and Physiology, Biomedical Research Center, Department of Biomedical Sciences, Laboratory of Cytometry, Department of Veterinary Anatomy, Optometry, University of Yaoundé 1, PO Box 812, Yaoundé, Cameroon

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Maulilio John Kipanyula Department of Animal Biology and Physiology, Biomedical Research Center, Department of Biomedical Sciences, Laboratory of Cytometry, Department of Veterinary Anatomy, Optometry, University of Yaoundé 1, PO Box 812, Yaoundé, Cameroon

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Mohammed Farahna Department of Animal Biology and Physiology, Biomedical Research Center, Department of Biomedical Sciences, Laboratory of Cytometry, Department of Veterinary Anatomy, Optometry, University of Yaoundé 1, PO Box 812, Yaoundé, Cameroon

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Yousef Aldebasi Department of Animal Biology and Physiology, Biomedical Research Center, Department of Biomedical Sciences, Laboratory of Cytometry, Department of Veterinary Anatomy, Optometry, University of Yaoundé 1, PO Box 812, Yaoundé, Cameroon

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Paul Faustin Seke Etet Department of Animal Biology and Physiology, Biomedical Research Center, Department of Biomedical Sciences, Laboratory of Cytometry, Department of Veterinary Anatomy, Optometry, University of Yaoundé 1, PO Box 812, Yaoundé, Cameroon

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increase in risk of developing breast, prostate, colon, endometrial, and ovarian cancers ( Alvino et al . 2011 , Tan et al . 2011 , Tzivion et al . 2011 , Mu et al . 2012 ). Data obtained from independent studies involving Drosophila model show

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Helen Gharwan National Cancer Institute, Women's Malignancies Branch, Department of Gynecologic Oncology, National Institutes of Health, 10 Center Drive, Building 10, 12N226, Bethesda, Maryland 20892-1906, USA

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Kristen P Bunch National Cancer Institute, Women's Malignancies Branch, Department of Gynecologic Oncology, National Institutes of Health, 10 Center Drive, Building 10, 12N226, Bethesda, Maryland 20892-1906, USA
National Cancer Institute, Women's Malignancies Branch, Department of Gynecologic Oncology, National Institutes of Health, 10 Center Drive, Building 10, 12N226, Bethesda, Maryland 20892-1906, USA

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Christina M Annunziata National Cancer Institute, Women's Malignancies Branch, Department of Gynecologic Oncology, National Institutes of Health, 10 Center Drive, Building 10, 12N226, Bethesda, Maryland 20892-1906, USA

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retrograde menstrual flow, those molecular alterations may facilitate endometrial tissue implantation on the surfaces of ovaries and/or peritoneum, thereby enabling tissue invasion and ultimately the manifestation of cancer ( Jarboe et al . 2008 , Bulun

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Catherine M Olsen Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Christina M Nagle Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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David C Whiteman Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Roberta Ness Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Celeste Leigh Pearce Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Malcolm C Pike Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia
Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Mary Anne Rossing Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Kathryn L Terry Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Anna H Wu Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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The Australian Cancer Study (Ovarian Cancer) Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Australian Ovarian Cancer Study Group Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia
Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Harvey A Risch Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Herbert Yu Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Jennifer A Doherty Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Jenny Chang-Claude Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Rebecca Hein Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Stefan Nickels Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Shan Wang-Gohrke Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Marc T Goodman Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Michael E Carney Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Rayna K Matsuno Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Galina Lurie Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Kirsten Moysich Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Susanne K Kjaer Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia
Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Allan Jensen Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Estrid Hogdall Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Ellen L Goode Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Brooke L Fridley Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Robert A Vierkant Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Melissa C Larson Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Joellen Schildkraut Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Cathrine Hoyo Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Patricia Moorman Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Rachel P Weber Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Daniel W Cramer Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Allison F Vitonis Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Elisa V Bandera Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Sara H Olson Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Lorna Rodriguez-Rodriguez Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Melony King Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Louise A Brinton Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Hannah Yang Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Montserrat Garcia-Closas Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Jolanta Lissowska Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Hoda Anton-Culver Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Argyrios Ziogas Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Simon A Gayther Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Susan J Ramus Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Usha Menon Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Aleksandra Gentry-Maharaj Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Penelope M Webb Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Introduction It is widely accepted that being overweight or obese increases a woman's risk of developing endometrial and post-menopausal breast cancer ( Calle & Kaaks 2004 ). The association with ovarian cancer is less clear, largely because

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Francesmary Modugno Department of Obstetrics, Department of Epidemiology, University of Pittsburgh Cancer Institute and Magee Womens Research Institute, Division of Gynecologic Oncology, Graduate Program in Molecular Pharmacology, Division of Medical Oncology, Department of Pharmacology and Chemical Biology, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Department of Obstetrics, Department of Epidemiology, University of Pittsburgh Cancer Institute and Magee Womens Research Institute, Division of Gynecologic Oncology, Graduate Program in Molecular Pharmacology, Division of Medical Oncology, Department of Pharmacology and Chemical Biology, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Department of Obstetrics, Department of Epidemiology, University of Pittsburgh Cancer Institute and Magee Womens Research Institute, Division of Gynecologic Oncology, Graduate Program in Molecular Pharmacology, Division of Medical Oncology, Department of Pharmacology and Chemical Biology, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

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Robin Laskey Department of Obstetrics, Department of Epidemiology, University of Pittsburgh Cancer Institute and Magee Womens Research Institute, Division of Gynecologic Oncology, Graduate Program in Molecular Pharmacology, Division of Medical Oncology, Department of Pharmacology and Chemical Biology, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Department of Obstetrics, Department of Epidemiology, University of Pittsburgh Cancer Institute and Magee Womens Research Institute, Division of Gynecologic Oncology, Graduate Program in Molecular Pharmacology, Division of Medical Oncology, Department of Pharmacology and Chemical Biology, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

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Ashlee L Smith Department of Obstetrics, Department of Epidemiology, University of Pittsburgh Cancer Institute and Magee Womens Research Institute, Division of Gynecologic Oncology, Graduate Program in Molecular Pharmacology, Division of Medical Oncology, Department of Pharmacology and Chemical Biology, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

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Courtney L Andersen Department of Obstetrics, Department of Epidemiology, University of Pittsburgh Cancer Institute and Magee Womens Research Institute, Division of Gynecologic Oncology, Graduate Program in Molecular Pharmacology, Division of Medical Oncology, Department of Pharmacology and Chemical Biology, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Department of Obstetrics, Department of Epidemiology, University of Pittsburgh Cancer Institute and Magee Womens Research Institute, Division of Gynecologic Oncology, Graduate Program in Molecular Pharmacology, Division of Medical Oncology, Department of Pharmacology and Chemical Biology, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

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Paul Haluska Department of Obstetrics, Department of Epidemiology, University of Pittsburgh Cancer Institute and Magee Womens Research Institute, Division of Gynecologic Oncology, Graduate Program in Molecular Pharmacology, Division of Medical Oncology, Department of Pharmacology and Chemical Biology, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

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Steffi Oesterreich Department of Obstetrics, Department of Epidemiology, University of Pittsburgh Cancer Institute and Magee Womens Research Institute, Division of Gynecologic Oncology, Graduate Program in Molecular Pharmacology, Division of Medical Oncology, Department of Pharmacology and Chemical Biology, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Department of Obstetrics, Department of Epidemiology, University of Pittsburgh Cancer Institute and Magee Womens Research Institute, Division of Gynecologic Oncology, Graduate Program in Molecular Pharmacology, Division of Medical Oncology, Department of Pharmacology and Chemical Biology, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

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Ovarian Cancer 2008 ). Finally, reproductive factors, such as early menarche and late menopause, which are associated with greater estrogen exposure and are linked to estrogen-associated breast and endometrial cancers, have not been consistently associated

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R Kaaks
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S Rinaldi
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T J Key
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significant effects, for example, on endometrial tissue ( Spark 2002 , Labrie et al . 2003 ). Although theoretically these potential advantages may seem attractive, our observation of an association of DHEAS levels with breast cancer risk strongly caution

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