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Paolo Vigneri Section of General Pathology, Section of Endocrinology, Department of Biomedical Sciences

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Francesco Frasca Section of General Pathology, Section of Endocrinology, Department of Biomedical Sciences

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Laura Sciacca Section of General Pathology, Section of Endocrinology, Department of Biomedical Sciences

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Giuseppe Pandini Section of General Pathology, Section of Endocrinology, Department of Biomedical Sciences

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Riccardo Vigneri Section of General Pathology, Section of Endocrinology, Department of Biomedical Sciences

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frequency of urinary tract infections is also likely to be involved. The risk of cancers of the female reproductive organs is also increased in DM. Both breast and endometrial cancer risks are increased in diabetic women, and this risk is independent from

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-09-0087
Volume/Issue:
Volume 16: Issue 4
Free access
Yi-Lin Chang Department of Life Science Institute of Biotechnology, National Dong Hwa University, Hualien 97401, Taiwan

Department of Pathology

Department of Dentistry Mennonite Hospital, Hualien 970, Taiwan, Republic of China

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Yu-Kan Hsu Department of Life Science Institute of Biotechnology, National Dong Hwa University, Hualien 97401, Taiwan

Department of Pathology

Department of Dentistry Mennonite Hospital, Hualien 970, Taiwan, Republic of China

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Tsung-Fan Wu Department of Life Science Institute of Biotechnology, National Dong Hwa University, Hualien 97401, Taiwan

Department of Pathology

Department of Dentistry Mennonite Hospital, Hualien 970, Taiwan, Republic of China

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Chieh-Ming Huang Department of Life Science Institute of Biotechnology, National Dong Hwa University, Hualien 97401, Taiwan

Department of Pathology

Department of Dentistry Mennonite Hospital, Hualien 970, Taiwan, Republic of China
Department of Life Science Institute of Biotechnology, National Dong Hwa University, Hualien 97401, Taiwan

Department of Pathology

Department of Dentistry Mennonite Hospital, Hualien 970, Taiwan, Republic of China

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Li-Yin Liou Department of Life Science Institute of Biotechnology, National Dong Hwa University, Hualien 97401, Taiwan

Department of Pathology

Department of Dentistry Mennonite Hospital, Hualien 970, Taiwan, Republic of China

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Ya-Wen Chiu Department of Life Science Institute of Biotechnology, National Dong Hwa University, Hualien 97401, Taiwan

Department of Pathology

Department of Dentistry Mennonite Hospital, Hualien 970, Taiwan, Republic of China

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Yu-Hsuan Hsiao Department of Life Science Institute of Biotechnology, National Dong Hwa University, Hualien 97401, Taiwan

Department of Pathology

Department of Dentistry Mennonite Hospital, Hualien 970, Taiwan, Republic of China

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Fuh-Jinn Luo Department of Life Science Institute of Biotechnology, National Dong Hwa University, Hualien 97401, Taiwan

Department of Pathology

Department of Dentistry Mennonite Hospital, Hualien 970, Taiwan, Republic of China

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Ta-Chun Yuan Department of Life Science Institute of Biotechnology, National Dong Hwa University, Hualien 97401, Taiwan

Department of Pathology

Department of Dentistry Mennonite Hospital, Hualien 970, Taiwan, Republic of China

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endometrial cancers; however, the role of ERs in oral squamous cell carcinoma (OSCC) is less understood. Previous studies have shown that the expression of ERα and ERβ in OSCC tumors and cell lines, and treatment with tamoxifen significantly, inhibits cell

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-14-0102
Volume/Issue:
Volume 21: Issue 4
Free access
Catherine M Olsen Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Christina M Nagle Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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David C Whiteman Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Roberta Ness Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Celeste Leigh Pearce Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Malcolm C Pike Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia
Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Mary Anne Rossing Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Kathryn L Terry Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Anna H Wu Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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The Australian Cancer Study (Ovarian Cancer) Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Australian Ovarian Cancer Study Group Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia
Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Harvey A Risch Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Herbert Yu Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Jennifer A Doherty Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Jenny Chang-Claude Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Rebecca Hein Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Stefan Nickels Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Shan Wang-Gohrke Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Marc T Goodman Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Michael E Carney Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Rayna K Matsuno Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Galina Lurie Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Kirsten Moysich Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Susanne K Kjaer Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia
Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Allan Jensen Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Estrid Hogdall Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Ellen L Goode Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Brooke L Fridley Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Robert A Vierkant Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Melissa C Larson Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Joellen Schildkraut Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Cathrine Hoyo Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Patricia Moorman Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Rachel P Weber Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Daniel W Cramer Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Allison F Vitonis Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Elisa V Bandera Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Sara H Olson Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Lorna Rodriguez-Rodriguez Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Melony King Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Louise A Brinton Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Hannah Yang Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Montserrat Garcia-Closas Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Jolanta Lissowska Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Hoda Anton-Culver Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Argyrios Ziogas Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Simon A Gayther Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Susan J Ramus Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Usha Menon Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Aleksandra Gentry-Maharaj Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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Penelope M Webb Queensland Institute of Medical Research, School of Public Health, Department of Preventive Medicine, Department of Epidemiology and Biostatistics, Program in Epidemiology, Obstetrics and Gynecology Epidemiology Center, Peter MacCallum Cancer Centre, Department of Epidemiology and Public Health, Cancer Epidemiology Program, Division of Cancer Epidemiology, Department of Obstetrics and Gynecology, Department of Biomedical Sciences, Department of Obstetrics and Gynecology, Roswell Park Cancer Center, Virus, Gynecologic Clinic, Department of Health Sciences Research, Department of Community and Family Medicine, Robert Wood Johnson Medical School, School of Public Health, National Cancer Institute, Division of Genetics and Epidemiology, Department of Cancer Epidemiology and Prevention, Department of Epidemiology, Department of Gynaecological Oncology, Royal Brisbane Hospital, Locked Bag 2000, Brisbane, Queensland 4029, Australia

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( Gilks & Prat 2009 ), compared with only an 8% increase in the previous study ( Collaborative Group on Epidemiological Studies of Ovarian Cancer 2012 ). Since endometrioid ovarian tumours are histologically similar to endometrial cancer ( Russell 1994

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G S Harrison
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M E Wierman
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T M Nett
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L M Glode
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-proliferative effects than GnRHR-I, has been identified in ovarian and endometrial cancers ( Kang et al. 2000 , Bedecarrats & Kaiser 2003 ); the significance of this remains to be determined as the role of GnRH-II has not been elucidated. Cancer types with

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Iman Azimi The School of Pharmacy, The University of Queensland, Brisbane, Queensland, Australia
Mater Research Institute, The University of Queensland, Brisbane, Queensland, Australia
Translational Research Institute, Brisbane, Queensland, Australia

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Gregory R Monteith The School of Pharmacy, The University of Queensland, Brisbane, Queensland, Australia
Mater Research Institute, The University of Queensland, Brisbane, Queensland, Australia
Translational Research Institute, Brisbane, Queensland, Australia

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Shen D Wang JL 2015 Ca2+ channel subunit alpha 1D promotes proliferation and migration of endometrial cancer cells mediated by 17beta-estradiol via the G protein-coupled estrogen receptor . FASEB Journal 29 2883 – 2893 . ( doi:10.1096/fj

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Catherine J Williams
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Nicholas Mitsiades
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Elias Sozopoulos Division of Endocrinology, Department of Pathology, Division of Nutritional Epidemiology, Diabetes and Metabolism, Department of Internal Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Stoneman 816, Boston, Massachusetts 02215, USA

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Alex Hsi
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Alicja Wolk Division of Endocrinology, Department of Pathology, Division of Nutritional Epidemiology, Diabetes and Metabolism, Department of Internal Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Stoneman 816, Boston, Massachusetts 02215, USA

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Artemissia-Phoebe Nifli
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Sofia Tseleni-Balafouta Division of Endocrinology, Department of Pathology, Division of Nutritional Epidemiology, Diabetes and Metabolism, Department of Internal Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Stoneman 816, Boston, Massachusetts 02215, USA

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Christos S Mantzoros
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2004 Circulating adiponectin and endometrial cancer risk . Journal of Clinical Endocrinology and Metabolism 89 1160 – 1163 . Ford ES 1999 Body mass index and colon cancer in a national sample of adult US men and women . American Journal of

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Hyun-Seuk Moon Division of Endocrinology, Section of Endocrinology, Diabetes, and Metabolism, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA

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Christos S Mantzoros Division of Endocrinology, Section of Endocrinology, Diabetes, and Metabolism, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
Division of Endocrinology, Section of Endocrinology, Diabetes, and Metabolism, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA

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human endometrial cancer cell lines ( Moon et al . 2011 ), we found that AD and/or Met increases activation of the tumor suppressor gene LKB1 in human and mouse colon cancer cell lines. In contrast to AD and Met, we observed that IL1β decreases LKB1

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Achim Fleischmann Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Bern, Murtenstrasse 31, PO Box 62, CH-3010 Bern, Switzerland

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Beatrice Waser Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Bern, Murtenstrasse 31, PO Box 62, CH-3010 Bern, Switzerland

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Jean Claude Reubi Division of Cell Biology and Experimental Cancer Research, Institute of Pathology, University of Bern, Murtenstrasse 31, PO Box 62, CH-3010 Bern, Switzerland

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-releasing peptide receptors in endometrial cancer . Journal of the American College of Surgeons 196 898 – 904 . Levine L Lucci JA III Pazdrak B Cheng JZ Guo YS Townsend CM Jr Hellmich MR 2003b Bombesin stimulates nuclear factor kappa B

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Shahab Uddin Human Cancer Genomic Research, Pathology, Departments of

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Prashant Bavi Human Cancer Genomic Research, Pathology, Departments of

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Abdul K Siraj Human Cancer Genomic Research, Pathology, Departments of

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Maqbool Ahmed Human Cancer Genomic Research, Pathology, Departments of

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Maha Al-Rasheed Human Cancer Genomic Research, Pathology, Departments of

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Azhar R Hussain Human Cancer Genomic Research, Pathology, Departments of

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Mohammed Ahmed Human Cancer Genomic Research, Pathology, Departments of

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Ali Alzahrani Human Cancer Genomic Research, Pathology, Departments of

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Fouad Al-Dayel Human Cancer Genomic Research, Pathology, Departments of

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Jehad Abubaker Human Cancer Genomic Research, Pathology, Departments of

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Rong Bu Human Cancer Genomic Research, Pathology, Departments of

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Khawla S Al-Kuraya Human Cancer Genomic Research, Pathology, Departments of

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alpha in human endometrial cancer . Annals of the New York Academy of Sciences 1095 90 – 98 . Leonhardt U Ritzel U Schafer G Becker W Ramadori G 1998 Serum leptin levels in hypo- and hyperthyroidism

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Céline Van Themsche Research Group in Molecular Oncology and Endocrinology, Department of Chemistry and Biology, Canada Research Chair in Molecular Gyneco-Oncology, Université du Québec à Trois-Rivières, 3351, Boul. des Forges, CP 500, Trois-Rivières, Québec, Canada G9A 5H7

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Sophie Parent Research Group in Molecular Oncology and Endocrinology, Department of Chemistry and Biology, Canada Research Chair in Molecular Gyneco-Oncology, Université du Québec à Trois-Rivières, 3351, Boul. des Forges, CP 500, Trois-Rivières, Québec, Canada G9A 5H7

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Valérie Leblanc Research Group in Molecular Oncology and Endocrinology, Department of Chemistry and Biology, Canada Research Chair in Molecular Gyneco-Oncology, Université du Québec à Trois-Rivières, 3351, Boul. des Forges, CP 500, Trois-Rivières, Québec, Canada G9A 5H7

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Caroline Descôteaux Research Group in Molecular Oncology and Endocrinology, Department of Chemistry and Biology, Canada Research Chair in Molecular Gyneco-Oncology, Université du Québec à Trois-Rivières, 3351, Boul. des Forges, CP 500, Trois-Rivières, Québec, Canada G9A 5H7

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Anne-Marie Simard Research Group in Molecular Oncology and Endocrinology, Department of Chemistry and Biology, Canada Research Chair in Molecular Gyneco-Oncology, Université du Québec à Trois-Rivières, 3351, Boul. des Forges, CP 500, Trois-Rivières, Québec, Canada G9A 5H7

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Gervais Bérubé Research Group in Molecular Oncology and Endocrinology, Department of Chemistry and Biology, Canada Research Chair in Molecular Gyneco-Oncology, Université du Québec à Trois-Rivières, 3351, Boul. des Forges, CP 500, Trois-Rivières, Québec, Canada G9A 5H7

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Eric Asselin Research Group in Molecular Oncology and Endocrinology, Department of Chemistry and Biology, Canada Research Chair in Molecular Gyneco-Oncology, Université du Québec à Trois-Rivières, 3351, Boul. des Forges, CP 500, Trois-Rivières, Québec, Canada G9A 5H7

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modulators (SERMs) and shows adverse agonistic activity on ER in the endometrium ( Jordan & O'Malley 2007 ): as a result, long-term use of tamoxifen is associated with increased endometrial cancer risk ( Fornander et al . 1989 , Fisher et al . 1994 ). In

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