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Jessica L Geiger Division of Hematology/Oncology, Department of Internal Medicine, University of Pittsburgh Cancer Institute, Division of Anatomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Pittsburgh Medical Center, Division of Molecular Genomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, 5150 Centre Avenue, 5th Floor, Pittsburgh, Pennsylvania, 15232, USA

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Simion I Chiosea Division of Hematology/Oncology, Department of Internal Medicine, University of Pittsburgh Cancer Institute, Division of Anatomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Pittsburgh Medical Center, Division of Molecular Genomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, 5150 Centre Avenue, 5th Floor, Pittsburgh, Pennsylvania, 15232, USA

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Sue M Challinor Division of Hematology/Oncology, Department of Internal Medicine, University of Pittsburgh Cancer Institute, Division of Anatomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Pittsburgh Medical Center, Division of Molecular Genomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, 5150 Centre Avenue, 5th Floor, Pittsburgh, Pennsylvania, 15232, USA

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Marina N Nikiforova Division of Hematology/Oncology, Department of Internal Medicine, University of Pittsburgh Cancer Institute, Division of Anatomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Pittsburgh Medical Center, Division of Molecular Genomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, 5150 Centre Avenue, 5th Floor, Pittsburgh, Pennsylvania, 15232, USA

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Julie E Bauman Division of Hematology/Oncology, Department of Internal Medicine, University of Pittsburgh Cancer Institute, Division of Anatomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Pittsburgh Medical Center, Division of Molecular Genomic Pathology, Department of Pathology, University of Pittsburgh Medical Center, 5150 Centre Avenue, 5th Floor, Pittsburgh, Pennsylvania, 15232, USA

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associated with complete obstruction and atelectasis, suspicious for a primary lung neoplasm, as well as bulky right-sided hilar and mediastinal lymphadenopathy ( Fig. 1 A and B). Endobronchial biopsy was consistent with a primary neuroendocrine neoplasm of

Article Type:
Editorial
DOI:
https://doi.org/10.1530/ERC-15-0307
Volume/Issue:
Volume 22: Issue 5
Free access
Julien Hadoux Oncologie Endocrinienne, Département d’Imagerie, Gustave Roussy, Villejuif, France

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Thomas Walter Service d’Oncologie, ENETS Centre of Excellence, Hospices Civils de Lyon et Université de Lyon, Lyon, France

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Christina Kanaan Service de Pathologie, Département de Biologie et Pathologie Médicale, Gustave Roussy, Villejuif, France

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Ségolène Hescot Département d’Oncologie, Institut Curie, Paris, France

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Vincent Hautefeuille Service d’Hépato-gastro-entérologie et Cancérologie Digestive, CHU Amiens Picardie, Amiens, France

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Marine Perrier Département d’Hépato-gastro-entérologie, CHU de Reims, Reims, France

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Igor Tauveron Service d'Endocrinologie, Diabétologie et Maladies Métaboliques, CHU Clermont-Ferrand, Clermont-Ferrand, France
Laboratoire GReD, Université Clermont Auvergne, Clermont-Ferrand, France

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Sandrine Laboureau Département d’Endocrinologie-Diabétologie-Nutrition, CHU d’Angers, Angers Cedex 9, France

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Christine Do Cao CHU de Lille, Service d’Endocrinologie, Lille, France

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Caroline Petorin CHU Clermont-Ferrand, Service de Chirurgie Digestive et Hépatobiliaire, Clermont-Ferrand, France

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Odile Blanchet CRB, CHU d’Angers, Angers Cedex 9, France

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Matthieu Faron Département de Chirurgie, Gustave Roussy, Villejuif, France

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Emmanuelle Leteurtre CANTHER - Cancer Heterogeneity Plasticity and Resistance to Therapies, Université de Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277, Lille, France

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Marie-Christine Rousselet Département de Pathologie, CHU d’Angers, Angers Cedex 9, France

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Juliette Joubert Zakeyh Laboratoire d’Anatomie Pathologique, CHU Clermont-Ferrand, Clermont-Ferrand, France

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Aude Marchal Service d’Anatomo-Pathologie, CHU Reims, Reims, France

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Denis Chatelain Service d’Anatomo-Pathologie, CHU Amiens, Amiens, France

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Clément Beaulaton Service d’Anatomo-Pathologie, Institut Curie, Paris, France

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Valérie Hervieu Service d’Anatomo-Pathologie, ENETS Centre of Excellence, Hospices Civils de Lyon et Université de Lyon, Lyon, France

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Catherine Lombard-Bohas Service d’Oncologie, ENETS Centre of Excellence, Hospices Civils de Lyon et Université de Lyon, Lyon, France

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Michel Ducreux Service d’Oncologie Digestive, Département de Médecine, Gustave Roussy, Villejuif, France
Faculté de Médecine, Université Paris Saclay, Le Kremlin-Bicêtre, France

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Jean-Yves Scoazec Service de Pathologie, Département de Biologie et Pathologie Médicale, Gustave Roussy, Villejuif, France
Faculté de Médecine, Université Paris Saclay, Le Kremlin-Bicêtre, France

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Eric Baudin Oncologie Endocrinienne, Département d’Imagerie, Gustave Roussy, Villejuif, France

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the Groupe d’Etude des Tumeurs Endocrines (GTE)
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the ENDOCAN-RENATEN network
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Patients This was a multicentre retrospective study of seven tertiary centres of the French expert network for the management of neuroendocrine neoplasms ENDOCAN-RENATEN (approved by the French National Cancer Institute, INCa). Patients were diagnosed

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-22-0102
Volume/Issue:
Volume 29: Issue 10
Restricted access
Mojun Zhu Department of Oncology, Mayo Clinic, Rochester, Minnesota, USA

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Karl R Sorenson Department of Oncology, Mayo Clinic, Rochester, Minnesota, USA

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Rebecca Liu Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA

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Bonnie E Gould Rothberg Smilow Cancer Hospital, Yale-New Haven Health System, New Haven, Connecticut, USA

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Thorvardur R Halfdanarson Department of Oncology, Mayo Clinic, Rochester, Minnesota, USA

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– 33 . ( https://doi.org/10.1097/MPA.0000000000001454 ) Hua J Shi S Xu J Wei M Zhang Y Liu J Zhang B Yu X 2020 Expression patterns and prognostic value of DNA damage repair proteins in resected pancreatic neuroendocrine neoplasms

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-21-0075
Volume/Issue:
Volume 28: Issue 12
Restricted access
Igryl S Cordero-Hernandez Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

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Alicia C Ross Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

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Arvind Dasari Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

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Daniel M Halperin Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

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Beth Chasen Department of Nuclear Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

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James C Yao Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA

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Introduction Neuroendocrine neoplasms (NEN) are a heterogenous group of malignancies, most commonly arising from gastroenteropancreatic (GEP) sites, with increasing incidence and prevalence worldwide ( Dasari et al. 2017 , Das & Dasari 2021

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-23-0203
Volume/Issue:
Volume 31: Issue 4
Restricted access
Louis de Mestier Université de Paris, Department of Gastroenterology-Pancreatology, Beaujon University Hospital (APHP), Clichy, France

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Angela Lamarca Division of Cancer Sciences, Department of Medical Oncology, The Christie NHS Foundation, University of Manchester, Manchester, United Kingdom

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Jorge Hernando Department of Medical Oncology, Vall d’Hebron University Hospital and Vall d´Hebron Institute of Oncology (VHIO), Barcelona, Spain

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Wouter Zandee Department of Internal Medicine, Sector Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, The Netherlands
Division of Endocrinology, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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Teresa Alonso-Gordoa Department of Medical Oncology, Ramon y Cajal University Hospital, IRYCIS, Madrid, Spain

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Marine Perrier Department of Hepato-Gastroenterology and Digestive Oncology, Robert-Debré University Hospital, Reims, France

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Annemiek ME Walenkamp Department of Medical Oncology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands

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Bipasha Chakrabarty Department of Pathology, The Christie, Manchester, United Kingdom

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Stefania Landolfi Department of Pathology, Vall d’Hebron University Hospital, Barcelona, Spain

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Marie-Louise F Van Velthuysen Department of Pathology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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Gursah Kats-Ugurlu Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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Alejandra Caminoa Department of Pathology, University Hospital Ramon y Cajal, Madrid, Spain

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Maxime Ronot Université de Paris, Department of Radiology, Beaujon University Hospital (APHP), Clichy, France

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Prakash Manoharan Department of Radiology and Nuclear Medicine, The Christie, Manchester, United Kingdom

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Alejandro Garcia-Alvarez Department of Medical Oncology, Vall d’Hebron University Hospital and Vall d´Hebron Institute of Oncology (VHIO), Barcelona, Spain

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Tessa Brabander Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands

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María Isabel García Gómez-Muriel Department of Radiology, University Hospital Ramon y Cajal, Madrid, Spain

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Guillaume Cadiot Department of Hepato-Gastroenterology and Digestive Oncology, Robert-Debré University Hospital, Reims, France

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Anne Couvelard Université de Paris, Department of Pathology, Beaujon/Bichat University Hospital (APHP), Clichy/Paris, France

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Jaume Capdevila Department of Medical Oncology, Vall d’Hebron University Hospital and Vall d´Hebron Institute of Oncology (VHIO), Barcelona, Spain

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Marianne E Pavel Department of Endocrinology, Erlangen University Hospital, Erlangen, Germany

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Jérôme Cros Université de Paris, Department of Pathology, Beaujon/Bichat University Hospital (APHP), Clichy/Paris, France

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Introduction The classification of neuroendocrine neoplasms (NENs) relies on differentiation (well-differentiated neuroendocrine tumors (NETs) or poorly-differentiated neuroendocrine carcinomas (NECs)) and the proliferation index, which is

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-21-0109
Volume/Issue:
Volume 28: Issue 8
Restricted access
Chiara Borga Department of Medicine (DIMED), Surgical Pathology & Cytopathology Unit, University of Padua, Padua, Italy

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Carlo Alberto Dal Pozzo Department of Medicine (DIMED), Surgical Pathology & Cytopathology Unit, University of Padua, Padua, Italy

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Elisabetta Trevellin Department of Medicine (DIMED), Endocrine-Metabolic Laboratory, University of Padua, Padua, Italy

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Francesca Bergamo Medical Oncology Unit 1, Department of Oncology, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy

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Sabina Murgioni Medical Oncology Unit 1, Department of Oncology, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy

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Anna Caterina Milanetto Department of Oncology, Surgery and Gastroenterology (DISCOG), Surgery 1, Pancreatic and Endocrine Digestive Surgical Unit, University of Padua, Padua, Italy

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Claudio Pasquali Department of Oncology, Surgery and Gastroenterology (DISCOG), Surgery 1, Pancreatic and Endocrine Digestive Surgical Unit, University of Padua, Padua, Italy

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Umberto Cillo Department of Oncology, Surgery and Gastroenterology (DISCOG), Hepatobiliary Surgery and Liver Transplant Unit, University of Padua, Padua, Italy

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Giada Munari Department of Medicine (DIMED), Surgical Pathology & Cytopathology Unit, University of Padua, Padua, Italy

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Chiara Martini Department of Medicine (DIMED), Endocrine-Metabolic Laboratory, University of Padua, Padua, Italy

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Eugenio De Carlo Department of Medicine (DIMED), Endocrine-Metabolic Laboratory, University of Padua, Padua, Italy

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Vittorina Zagonel Medical Oncology Unit 1, Department of Oncology, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy

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Vincenza Guzzardo Department of Medicine (DIMED), Surgical Pathology & Cytopathology Unit, University of Padua, Padua, Italy

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Gianmaria Pennelli Department of Medicine (DIMED), Surgical Pathology & Cytopathology Unit, University of Padua, Padua, Italy

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Angelo Paolo Dei Tos Department of Medicine (DIMED), Surgical Pathology & Cytopathology Unit, University of Padua, Padua, Italy

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Roberto Vettor Department of Medicine (DIMED), Endocrine-Metabolic Laboratory, University of Padua, Padua, Italy

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Matteo Fassan Department of Medicine (DIMED), Surgical Pathology & Cytopathology Unit, University of Padua, Padua, Italy
Veneto Institute of Oncology IOV - IRCCS, Padua, Italy

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Introduction Gastrointestinal neuroendocrine neoplasms (GI-NENs) are a heterogeneous group of malignancies that represent an emerging issue both in research and clinical practice due to their increase in incidence ( Patel & Benipal 2019 ) and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-21-0052
Volume/Issue:
Volume 28: Issue 7
Restricted access
Andrew McDonald Winship Cancer Institute at Emory University, Atlanta, Georgia, USA

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Vaidehi Avadhani Grady Memorial Hospital, Atlanta, Georgia, USA

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Gabriela Oprea-Ilies Grady Memorial Hospital, Atlanta, Georgia, USA

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Katerina Zakka Winship Cancer Institute at Emory University, Atlanta, Georgia, USA

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Gregory B Lesinski Winship Cancer Institute at Emory University, Atlanta, Georgia, USA

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Olumide B Gbolahan Winship Cancer Institute at Emory University, Atlanta, Georgia, USA

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Olatunji Alese Winship Cancer Institute at Emory University, Atlanta, Georgia, USA

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Introduction Neuroendocrine neoplasms (NENs) of the gastroenteropancreatic (GEP) system are a heterogeneous group of rare malignancies. While the incidence of NENs was relatively low, with 6.98 cases per 100,000 adults in 2012, the incidence

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-24-0046
Volume/Issue:
Volume 31: Issue 10
Restricted access
Matthew H Kulke Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA

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protein that is contained in the neurosecretory vesicles of neuroendocrine tumor cells, and has been identified in the plasma of patients with endocrine neoplasms. Plasma CGA concentrations are a more sensitive marker than urinary 5-HIAA levels in patients

Article Type:
Review Article
DOI:
https://doi.org/10.1677/ERC-06-0061
Volume/Issue:
Volume 14: Issue 2
Free access
Martin B Niederle
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Monika Hackl Division of General Surgery, Bundesanstalt ‘Statistik Österreich’ (Austria Statistics), Department of Clinical Pathology, Section of Endocrine Surgery, Department of Surgery, Medical University of Vienna, Währinger Gürtel 18–20, A-1090 Vienna, Austria

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Klaus Kaserer Division of General Surgery, Bundesanstalt ‘Statistik Österreich’ (Austria Statistics), Department of Clinical Pathology, Section of Endocrine Surgery, Department of Surgery, Medical University of Vienna, Währinger Gürtel 18–20, A-1090 Vienna, Austria

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Bruno Niederle
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Introduction Neuroendocrine tumours (NETs) of the gastrointestinal tract are rare neoplasms and represent a heterogeneous group of tumours with distinct functional and biological behaviour depending on location, tumour size and clinical symptoms

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-10-0152
Volume/Issue:
Volume 17: Issue 4
Free access
Sarah B Bateni Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
University of Alabama at Birmingham, Department of Surgery, Division of Surgical Oncology, Birmingham, Alabama, USA

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Natalie G Coburn Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada

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Calvin Law Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

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Simron Singh Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada

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Sten Myrehaug Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada

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Angela Assal Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada

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Julie Hallet Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada

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.4160 ) Massironi S Campana D Pusceddu S Albertelli M Faggiano A Panzuto F Smiroldo V Andreasi V Rossi RE Maggio I , 2020 Second primary neoplasms in patients with lung and gastroenteropancreatic neuroendocrine neoplasms: data from a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-22-0337
Volume/Issue:
Volume 30: Issue 8
Restricted access