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Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK
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tumour cell-intrinsic pathways to bolster anti-tumour immunity and overcome chemo-/radioresistance afforded by PTEN deficiency in PCa. Prostate tumours additionally partake in crosstalk with their encapsulating stroma in order to remodel the TME and
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Jhiang S Ringel MD et al . 2019 Inhibiting BRAF Oncogene-Mediated Radioresistance Effectively Radiosensitizes BRAFV600E-Mutant Thyroid Cancer Cells by Constraining DNA Double-Strand Break Repair . Clinical Cancer Research 25 4749 – 4760