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Himisha Beltran Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA

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Francesca Demichelis Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento, Italy

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). Extracellular vesicles (EVs) derived from metastatic tumor cells can also be detected in the circulation in men with CRPC, including those that are CTC-negative, and may carry tumor-associated proteins that can be quantified and tracked serially ( Gerdtsson et

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