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Department of Pathology and Cancer Diagnostics, Karolinska University Hospital, Stockholm, Sweden
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Endocrine Oncology Site, Princess Margaret Cancer Centre, Toronto, ON, Canada
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada
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al. 2022 ). Overall, oncocytic thyroid tumors represent a distinct entity of thyroid neoplasms, supported by specific genetic aberrations including mitochondrial DNA mutations and increased copy number alterations ( Gopal et al. 2018 , Doerfler
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Comprehensive Cancer Centre Mainfranken, University of Wuerzburg Medical Centre, Wuerzburg, Germany
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Department of Medicine, Division of Endocrinology and Diabetes, University Hospital, University of Wuerzburg, Wuerzburg, Germany
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Comprehensive Cancer Centre Mainfranken, University of Wuerzburg Medical Centre, Wuerzburg, Germany
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such as age, further pathological factors such as Ki67 proliferation index, and potentially even genetic evaluation (genomics, transcriptomics, proteomics) may be needed to augment the AFIP scoring system. Such a stratification has already been achieved