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Andreas Venizelos
Andreas Venizelos
K.G. Jebsen Center for Genome-Directed Cancer Therapy, Department of Clinical Science, University of Bergen, Bergen, Norway
Department of Oncology, Haukeland University Hospital, Bergen, Norway
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Department of Oncology, Haukeland University Hospital, Bergen, Norway
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Hege Elvebakken
Hege Elvebakken
Department of Oncology, Ålesund Hospital, Møre og Romsdal Hospital Trust, Ålesund, Norway
Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
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Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
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Aurel Perren
Aurel Perren
Institute of Pathology, University of Bern, Bern, Switzerland
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Oleksii Nikolaienko
Oleksii Nikolaienko
K.G. Jebsen Center for Genome-Directed Cancer Therapy, Department of Clinical Science, University of Bergen, Bergen, Norway
Department of Oncology, Haukeland University Hospital, Bergen, Norway
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Department of Oncology, Haukeland University Hospital, Bergen, Norway
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Wei Deng
Wei Deng
K.G. Jebsen Center for Genome-Directed Cancer Therapy, Department of Clinical Science, University of Bergen, Bergen, Norway
Department of Oncology, Haukeland University Hospital, Bergen, Norway
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Department of Oncology, Haukeland University Hospital, Bergen, Norway
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Inger Marie B Lothe
Inger Marie B Lothe
Department of Pathology, Oslo University Hospital, Oslo, Norway
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Anne Couvelard
Anne Couvelard
Department of Pathology, Université de Paris, Bichat Hospital, AP-HP, Paris, France
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Geir Olav Hjortland
Geir Olav Hjortland
Department of Oncology, Oslo University Hospital, Oslo, Norway
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Anna Sundlöv
Anna Sundlöv
Departmentt of Oncology, Skåne University Hospital, Lund, Sweden
Department of Medical Radiation Physics, Lund University, Lund, Sweden
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Department of Medical Radiation Physics, Lund University, Lund, Sweden
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Johanna Svensson
Johanna Svensson
Department of Oncology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Harrish Garresori
Harrish Garresori
Department of Oncology, Stavanger University Hospital, Stavanger, Norway
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Christian Kersten
Christian Kersten
Department of Research, Hospital of Southern Norway, Kristiansand, Norway
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Eva Hofsli
Eva Hofsli
Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
Department of Oncology, St.Olavs Hospital, Trondheim, Norway
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Department of Oncology, St.Olavs Hospital, Trondheim, Norway
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Sönke Detlefsen
Sönke Detlefsen
Department of Pathology, Odense University Hospital, Odense, Denmark
Department of Clinical Medicine, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark
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Department of Clinical Medicine, Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark
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Merete Krogh
Merete Krogh
Department of Oncology, Odense University Hospital, Odense, Denmark
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Halfdan Sorbye
Halfdan Sorbye
Department of Oncology, Haukeland University Hospital, Bergen, Norway
Department of Clinical Science, University of Bergen, Bergen, Norway
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Department of Clinical Science, University of Bergen, Bergen, Norway
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Stian Knappskog
Stian Knappskog
K.G. Jebsen Center for Genome-Directed Cancer Therapy, Department of Clinical Science, University of Bergen, Bergen, Norway
Department of Oncology, Haukeland University Hospital, Bergen, Norway
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Department of Oncology, Haukeland University Hospital, Bergen, Norway
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Introduction High-grade (HG) gastroenteropancreatic (GEP) neuroendocrine neoplasms (NEN) are defined by the presence of neuroendocrine phenotype and a high proliferation rate (Ki-67 > 20%). The HG NEN entity consists of well
James C Yao
James C Yao
University of Texas MD Anderson Cancer Center, Houston, Texas, USA
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Jonathan Strosberg
Jonathan Strosberg
Department of GI Oncology, Moffitt Cancer Center, Tampa, Florida, USA
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Nicola Fazio
Nicola Fazio
European Institute of Oncology, IEO, IRCCS, Milan, Italy
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Marianne E Pavel
Marianne E Pavel
Department of Medicine 1, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany
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Emily Bergsland
Emily Bergsland
UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, USA
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Philippe Ruszniewski
Philippe Ruszniewski
Hôpital Beaujon, University of Paris, Paris, France
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Daniel M Halperin
Daniel M Halperin
University of Texas MD Anderson Cancer Center, Houston, Texas, USA
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Daneng Li
Daneng Li
City of Hope Comprehensive Cancer Center and Beckman Research Institute, Duarte, California, USA
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Salvatore Tafuto
Salvatore Tafuto
Sarcomas and Rare Tumours Unit, Istituto Nazionale Tumori, IRCCS Fondazione G. Pascale, Naples, Italy
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Nitya Raj
Nitya Raj
Memorial Sloan Kettering Cancer Center, New York, New York, USA
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Davide Campana
Davide Campana
Department of Clinical Medicine, Sant’Orsola-Malpighi Hospital, University of Bologna, ENETS Center of Excellence, Bologna, Italy
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Susumu Hijioka
Susumu Hijioka
National Cancer Center Japan Tsukiji Campus, Department of Hepatobiliary and Pancreatic Oncology, Tokyo, Japan
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Markus Raderer
Markus Raderer
Clinical Division of Oncology, Medical University of Vienna, Vienna, Austria
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Rosine Guimbaud
Rosine Guimbaud
CHU de Toulouse, Toulouse, France
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Pablo Gajate
Pablo Gajate
Hospital Universitário Ramón y Cajal, Clinical Oncology Department, Madrid, Spain
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Sara Pusceddu
Sara Pusceddu
Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
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Albert Reising
Albert Reising
Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA
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Evgeny Degtyarev
Evgeny Degtyarev
Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA
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Mark Shilkrut
Mark Shilkrut
Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA
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Simantini Eddy
Simantini Eddy
Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA
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Simron Singh
Simron Singh
Sunnybrook Health Sciences Centre, Toronto, Canada
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years ( Yao et al. 2008 ). Neuroendocrine neoplasms (NENs) are comprised of well-differentiated NETs and poorly differentiated neuroendocrine carcinomas (NECs). The World Health Organization classification reported four categories, based on tumor
