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WM, Santoro M, Fusco A et al. 1998 The RET/PTC3 oncogene: metastatic solid-type papillary carcinomas in murine thyroids. Cancer Research 58 5523 –5528. Rhoades MW , Reinhart BJ, Lim LP, Burge CB, Bartel B & Bartel

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Carlo Maria Croce
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Alfredo Fusco
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described in 10 out of 28 papillary carcinomas, 3 out of 9 follicular carcinomas, and 6 out of 8 anaplastic carcinomas. Moreover, 80% of p27 Kip1 -expressing tumors show an uncommon cytoplasmic localization of p27 Kip1 protein, associated with a high Cdk2

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Alfred King-yin Lam Cancer Molecular Pathology, School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia

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Nassim Saremi Cancer Molecular Pathology, School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia

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Koshy A Hyjek E Stenson K Cohen RN Yeo KT 2015 Discrepant serum and urine β-hCG results due to production of β-hCG by a cribriform-morular variant of thyroid papillary carcinoma . Clinica Chimica Acta 438 181 – 185 . ( doi:10

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Alfred King-yin Lam School of Medicine, Griffith University, Gold Coast, Australia

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– 280 . Ashraf MJ Azarpira N Khademi B Peiravi M 2010 Squamous cell carcinoma associated with tall cell variant of papillary carcinoma of the thyroid . Indian Journal of Pathology and Microbiology 53 548 – 550 . ( https://doi.org/10

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Arivarasan Karunamurthy Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

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Federica Panebianco Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

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Susan J Hsiao Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

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Jennie Vorhauer Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

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Marina N Nikiforova Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

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Simion Chiosea Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

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Yuri E Nikiforov Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

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of thyroid papillary carcinomas . American Journal of Surgical Pathology 30 216 – 222 . Battiste JL Pestova TV Hellen CU Wagner G 2000 The eIF1A solution structure reveals a large RNA-binding surface important for scanning

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A Bastagli
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locations had light microscopic and immunohistochemical features diagnostic of papillary carcinoma and, due to their size, were classified as ‘papillary microcarcinoma’ according to the current WHO classification of thyroid tumours ( Hedinger et al. 1989

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Natassia E Bufalo Laboratory of Cancer Molecular Genetics, Medical Sciences School, State University of Campinas – UNICAMP, Sao Paulo, Brazil

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Janaina L Leite Laboratory of Cancer Molecular Genetics, Medical Sciences School, State University of Campinas – UNICAMP, Sao Paulo, Brazil

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Ana C T Guilhen Laboratory of Cancer Molecular Genetics, Medical Sciences School, State University of Campinas – UNICAMP, Sao Paulo, Brazil

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Elaine C Morari Laboratory of Cancer Molecular Genetics, Medical Sciences School, State University of Campinas – UNICAMP, Sao Paulo, Brazil

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Fabiana Granja Laboratory of Cancer Molecular Genetics, Medical Sciences School, State University of Campinas – UNICAMP, Sao Paulo, Brazil

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Ligia V M Assumpcao Laboratory of Cancer Molecular Genetics, Medical Sciences School, State University of Campinas – UNICAMP, Sao Paulo, Brazil

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Laura S Ward Laboratory of Cancer Molecular Genetics, Medical Sciences School, State University of Campinas – UNICAMP, Sao Paulo, Brazil

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benign thyroid lesions, including 67 multinodular goiters and 13 follicular adenomas, as well as 168 cases of malignant thyroid tumors, including 136 papillary carcinomas and 32 follicular carcinomas. Differentiation stage and grade of the tumors were

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M Silvy
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C De Micco
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.31/1 and the mean age was 50.0 years (range, 23–74 years). The carcinomas ( n = 62) included 11 minimally invasive follicular carcinomas (FCmi), ten widely invasive follicular carcinomas (FCwi), 20 classical papillary carcinomas (PCc) (13 with purely

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Gahee Park Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of
Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Tae Hyuk Kim Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Hae-Ock Lee Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Jung Ah Lim Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of
Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Jae-Kyung Won Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Hye Sook Min Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Kyu Eun Lee Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Do Joon Park Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Young Joo Park Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Woong-Yang Park Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of
Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of
Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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clinicopathological characterization of ALK -rearranged papillary carcinoma. Subjects and methods Case selection This study included 474 formalin-fixed paraffin-embedded (FFPE) samples from patients with benign and malignant thyroid tumors collected from 1993 to 2002

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A Bakhsh
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G Kirov
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J W Gregory
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E D Williams
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M Ludgate
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of papillary carcinomas ( Kimura et al. 2003 , Soares et al. 2003 ), and the great majority of papillary carcinomas show either a BRAF mutation or a rearrangement, usually involving RET, rarely TRK. Translocations between chromosomes 2 and 3 have

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