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Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
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Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
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Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
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Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
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Uro-Oncology Research, Surgery, Biomedical Sciences, Biostatistics and Bioinformatics Center, Department of Pathology, Department of Pathology, Department of Biochemistry and Cell Biology, Department of Medicine, Samuel Oschin Comprehensive Cancer Center, Cedars-Sinai Medical Center, 8750 Beverly Blvd., Atrium 103, Los Angeles, California 90048, USA Departments of
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). Receptor activator of NF-κB ligand (RANKL)–RANK signaling has many crucial physiological roles in bone and other tissues ( Hanada et al . 2009 ), and aberrant RANKL–RANK signaling in cancer and bone cells affects cancer bone colonization ( Dougall 2011
Department of Cancer Cell Biology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, People’s Republic of China
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Department of Clinical Sciences, College of Medicine, University of South Florida, Tampa, Florida, USA
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Department of Clinical Sciences, College of Medicine, University of South Florida, Tampa, Florida, USA
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cell lines for each of the four drugs. Several different statistical methods have been used for this analysis, including Pearson product–moment correlation, Spearman’s rank-order correlation, Welch’s two-sample t -test by grouping the cell line into
Division of Hematology/Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Department of Epidemiology and Biostatistics, University of California, San Francisco, California, USA
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Division of Hematology/Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Department of Epidemiology and Biostatistics, University of California, San Francisco, California, USA
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Division of Hematology/Oncology, Department of Medicine, University of California, San Francisco, California, USA
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unspecified. The median (interquartile range) follow-up time for our lung NET cohort was 8.7 years (2.6-12.8). Statistical analysis Patient characteristics at diagnosis were compared by stage using the Wilcoxon rank sum test for continuous variables
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and brain tumorigenesis. Subjects and methods Meta-analysis of public microarray data We used the rank-product method, which ranks the ratio of expression levels and tests the significance which is a product of the corresponding ranks. Normal (N), low
Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
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Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
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Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
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Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
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Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
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Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
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Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
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Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
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Departments of Oncology-Pathology, Molecular Medicine and Surgery, Cancer Center Karolinska (CCK), Department of Breast and Endocrine Surgery, Karolinska Institutet, Stockholm, Sweden
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were compared using log-rank test. Overall survival was the period from the time of diagnosis until the end of follow-up or death of the patient. For overall survival analysis, survival was censored if patients were still alive at the end of the follow
Department of Molecular Medicine and Surgery, Center for Molecular Medicine, Department of Oncology‐Pathology, Department of Breast and Endocrine Surgery, Karolinska Institutet, SE-17176 Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Center for Molecular Medicine, Department of Oncology‐Pathology, Department of Breast and Endocrine Surgery, Karolinska Institutet, SE-17176 Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Center for Molecular Medicine, Department of Oncology‐Pathology, Department of Breast and Endocrine Surgery, Karolinska Institutet, SE-17176 Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Center for Molecular Medicine, Department of Oncology‐Pathology, Department of Breast and Endocrine Surgery, Karolinska Institutet, SE-17176 Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Center for Molecular Medicine, Department of Oncology‐Pathology, Department of Breast and Endocrine Surgery, Karolinska Institutet, SE-17176 Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Center for Molecular Medicine, Department of Oncology‐Pathology, Department of Breast and Endocrine Surgery, Karolinska Institutet, SE-17176 Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Center for Molecular Medicine, Department of Oncology‐Pathology, Department of Breast and Endocrine Surgery, Karolinska Institutet, SE-17176 Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Center for Molecular Medicine, Department of Oncology‐Pathology, Department of Breast and Endocrine Surgery, Karolinska Institutet, SE-17176 Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Center for Molecular Medicine, Department of Oncology‐Pathology, Department of Breast and Endocrine Surgery, Karolinska Institutet, SE-17176 Stockholm, Sweden
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with survival was studied using Kaplan–Meier plots, and the curves for each group were compared by log-rank test. All the analyses were two-tailed and P values <0.05 were considered significant. Results Deregulated miRNAs in ACC In this study, we
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date of the first tumor recurrence, including loco-regional recurrence, distant metastasis or death. The Kaplan–Meier method was used to estimate the RFS, and the estimated survival curves were compared using the log-rank test. The Cox’s regression
Nanfang Neurosurgery Research Institution, Nanfang hospital, Southern Medical University, Guangzhou, China
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Nanfang Neurosurgery Research Institution, Nanfang hospital, Southern Medical University, Guangzhou, China
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Nanfang Neurosurgery Research Institution, Nanfang hospital, Southern Medical University, Guangzhou, China
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Nanfang Neurosurgery Research Institution, Nanfang hospital, Southern Medical University, Guangzhou, China
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Nanfang Neurosurgery Research Institution, Nanfang hospital, Southern Medical University, Guangzhou, China
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, version 11.5 (SPSS), using an unpaired t -test, one-way ANOVA analysis with post hoc Tukey’s test or Spearman’s rank correlation coefficient followed by simple main effect test. P < 0.05 was considered statistically significant. Results
European Network for the Study of Adrenal Tumors (ENS@T) Center of Excellence, Florence, Italy
Centro di Ricerca e Innovazione sulle Patologie Surrenaliche, AOU Careggi, Florence, Italy
Istituto Nazionale Biostrutture e Biosistemi (I.N.B.B.), via delle Medaglie D’Oro, Rome, Italy
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European Network for the Study of Adrenal Tumors (ENS@T) Center of Excellence, Florence, Italy
Centro di Ricerca e Innovazione sulle Patologie Surrenaliche, AOU Careggi, Florence, Italy
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European Network for the Study of Adrenal Tumors (ENS@T) Center of Excellence, Florence, Italy
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European Network for the Study of Adrenal Tumors (ENS@T) Center of Excellence, Florence, Italy
Centro di Ricerca e Innovazione sulle Patologie Surrenaliche, AOU Careggi, Florence, Italy
Istituto Nazionale Biostrutture e Biosistemi (I.N.B.B.), via delle Medaglie D’Oro, Rome, Italy
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for continuous variables. Comparison between two groups of data was accomplished using Student’s t- test for normally distributed variables and Mann–Whitney U test for nonparametric variables or paired Wilcoxon’s signed-rank test. Regarding the
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Department of Medicine III, University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
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Medicover Oldenburg MVZ, Oldenburg, Germany
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Department for Endocrinology, Diabetology and Clinical Nutrition, UniversitätsSpital Zürich, Zurich, Switzerland
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Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Madrid, Spain
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Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Hals-Chirurgie, Plastische Operationen, Städtisches Klinikum Dresden, Akademisches Lehrkrankenhaus der Technischen Universität Dresden, Dresden, Germany
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Department of Medicine III, University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
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methoxytyramine (MTY) and normetanephrine (NMN) in patients with and without HNPGLs. (A, B, C, D, E and F) Significance was calculated by Wilcoxon rank-sum test. (G) Plasma MTY was plotted against tumor diameter, and linear regression with 95% CI was fitted