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Medizinische Klinik und Poliklinik III, University Hospital Carl Gustav Carus Dresden, Dresden, Germany
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of the ER stress markers CHOP and XBP1 S/U in mitotane-treated H295R across all concentrations, which increased in combination with either LXRα inhibitor ( Fig. 2C ). Figure 2 (A) Graphical representation of percentage AnnexinV positive
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Department of Breast, Endocrine Tumors and Sarcoma, Karolinska University Hospital, Stockholm, Sweden
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Department of Breast, Endocrine Tumors and Sarcoma, Karolinska University Hospital, Stockholm, Sweden
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Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden
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among established genes None SQSTM1-NTRK3 None BRAF V600E NCOA4-RET Constitutional event* CHEK2 p.410fs None None None None Mutational aggregation in primary tumor # XBP1(S) activates chaperone genes Translocation of
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, Smad2, Map3k1, Tob1, Ywhag/14-3-3γ, Ywhab/14-3-3β, Smad5, Zfp36, Xbp1, Mapk12 and Snail ( Perdigao-Henriques et al . 2016 ). BMP-2 appears to promote motility and invasiveness of MCF-7 and MDA-MB-231 cells, both in vitro and in vivo ( Clement et