similar to those detected by CGH analysis. The most obvious was the gain of erythroblastic leukemia viral oncogene homolog 2 ( ERBB-2 ) oncogene located on chromosome 17q that was more common in malignant pheochromocytomas. Moreover, we analyzed the ERBB
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WenQi Yuan, WeiQinq Wang, Bin Cui, TingWei Su, Yan Ge, Lei Jiang, WeiWei Zhou, and Guang Ning
Samuel M O’Toole, David S Watson, Tatiana V Novoselova, Lisa E L Romano, Peter J King, Teisha Y Bradshaw, Clare L Thompson, Martin M Knight, Tyson V Sharp, Michael R Barnes, Umasuthan Srirangalingam, William M Drake, and J Paul Chapple
.1016/j.ccell.2017.01.009 ) 28196587 10.1016/j.ccell.2017.01.009 Dannenberg H De Krijger RR van der Harst E Abbou M Ijzendoorn Y Komminoth P Dinjens WN 2003 Von Hippel-Lindau gene alterations in sporadic benign and malignant pheochromocytomas
Tiantian Liu, Taylor C Brown, C Christofer Juhlin, Adam Andreasson, Na Wang, Martin Bäckdahl, James M Healy, Manju L Prasad, Reju Korah, Tobias Carling, Dawei Xu, and Catharina Larsson
%) 4/81 (5%) Adrenocortical carcinoma (ACC) 3/27 (11%) 1/7 (14%) 4/34 (12%) Adrenocortical adenoma (ACA) 0/21 0/26 0/47 Pheochromocytoma (PCC) 0/86 1/19 (5%) 1/105 (1%) Malignant PCC a 0/10 – 0/10 Benign PCC 0
Nimrod B Kiss, Andreas Muth, Adam Andreasson, C Christofer Juhlin, Janos Geli, Martin Bäckdahl, Anders Höög, Bo Wängberg, Ola Nilsson, Håkan Ahlman, and Catharina Larsson
extended tumor panel of pheochromocytomas and paragangliomas. Notably and as our previous findings indicated a presence of CIMP in strong association with malignant paragangliomas with SDHB mutation ( Geli et al . 2008 , Kiss et al . 2008 ), the
Camilo Jimenez, Bennett B Chin, Richard B Noto, Joseph S Dillon, Lilja Solnes, Nancy Stambler, Vincent A DiPippo, and Daniel A Pryma
Babich JW 2009 Radiation dosimetry, pharmacokinetics, and safety of ultratrace iobenguane I-131 in patients with malignant pheochromocytoma/paraganglioma or metastatic carcinoid . Cancer Biotherapy and Radiopharmaceuticals 24 469 – 475 . ( https
Diana E Benn, Bruce G Robinson, and Roderick J Clifton-Bligh
Rieubland C Crespin M Nau V Khau VanKien P Corvol P Plouin PF Jeunemaitre X 2003 Mutations in the SDHB gene are associated with extra-adrenal and/or malignant pheochromocytomas . Cancer Research 63 5615 – 5621 . Gimenez
Anne-Paule Gimenez-Roqueplo, Mercedes Robledo, and Patricia L M Dahia
First International Randomized Study in Malignant Progressive Pheochromocytoma and Paragangliomas (FIRSTMAPPP): an academic double-blind trial investigating sunitinib . Annals of Oncology 32 S621. ( https://doi.org/10.1016/j.annonc.2021.08.702 ) Ben
Ruth T Casey, Benjamin G Challis, Alison Marker, Deborah Pitfield, Heok K Cheow, Ashley Shaw, Soo-Mi Park, Helen L Simpson, and Eamonn R Maher
, we report a further case of a malignant PGL in a 46-year-old man with a succinate dehydrogenase complex flavoprotein subunit A ( SDHA ) germline mutation (c.91C > T, p.Arg31*). In the case we describe, following the initial surgical removal of a left
Susan Richter, Timothy J Garrett, Nicole Bechmann, Roderick J Clifton-Bligh, and Hans K Ghayee
regression and stability with treatment ( Joshua et al. 2009 ). Newer data from the First International Randomized Study in Malignant Progressive Pheochromocytoma and Paragangliomas (FIRSTMAPPP, NCT01371201) indicate that 35.9% of patients with progressive
J Crona, F Beuschlein, K Pacak, and B Skogseid
dacarbazine treatment improves survival in patients with metastatic and unresectable malignant pheochromocytomas/paragangliomas . Hormones and Cancer 8 108 – 118 . ( https://doi.org/10.1007/s12672-017-0284-7 ) 10.1007/s12672-017-0284-7 Assie G Letouze E
