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Paul Benjamin Loughrey Patrick G Johnston Centre for Cancer Research, Queen’s University Belfast, Belfast, UK
Regional Centre for Endocrinology and Diabetes, Belfast Health and Social Care Trust, Belfast, UK

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Brian Herron Department of Cellular Pathology, Belfast Health and Social Care Trust, Belfast, UK

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Stephen Cooke Department of Neurosurgery, Belfast Health and Social Care Trust, Belfast, UK

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Philip Weir Department of Neurosurgery, Belfast Health and Social Care Trust, Belfast, UK

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Jayna Elizabeth Smyth Regional Centre for Endocrinology and Diabetes, Belfast Health and Social Care Trust, Belfast, UK

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Karen R Mullan Regional Centre for Endocrinology and Diabetes, Belfast Health and Social Care Trust, Belfast, UK

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Estelle G Healy Department of Cellular Pathology, Belfast Health and Social Care Trust, Belfast, UK

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Jane Evanson Department of Radiology, Barts Health NHS Trust, London, UK

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Stephanie G Craig Patrick G Johnston Centre for Cancer Research, Queen’s University Belfast, Belfast, UK

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Jacqueline A James Patrick G Johnston Centre for Cancer Research, Queen’s University Belfast, Belfast, UK
Department of Cellular Pathology, Belfast Health and Social Care Trust, Belfast, UK
Northern Ireland Biobank, Belfast Health and Social Care Trust, Belfast, UK

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Márta Korbonits Department of Endocrinology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK

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Steven J Hunter Regional Centre for Endocrinology and Diabetes, Belfast Health and Social Care Trust, Belfast, UK

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( Fleseriu et al. 2021 , Valassi 2022 ). Mortality in CD has repeatedly been shown to be raised in relation to the general population and is largely due to cardiovascular events, and this persists despite cure of CD with bilateral adrenalectomy ( Fountas

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-24-0028
Volume/Issue:
Volume 31: Issue 9
Open access
Adriana Albani Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität München, Munich, Germany

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Luis Gustavo Perez-Rivas Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität München, Munich, Germany

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Sicheng Tang Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität München, Munich, Germany

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Julia Simon Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität München, Munich, Germany

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Kristin Elisabeth Lucia Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität München, Munich, Germany

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Paula Colón-Bolea Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität München, Munich, Germany

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Jochen Schopohl Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität München, Munich, Germany

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Sigrun Roeber Center for Neuropathology and Prion Research, LMU Munich, Munich, Germany

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Michael Buchfelder Department of Neurosurgery, University of Erlangen-Nürnberg, Erlangen, Germany

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Roman Rotermund Department of Neurosurgery, Universitätskrankenhaus Hamburg-Eppendorf, Hamburg, Germany

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Jörg Flitsch Department of Neurosurgery, Universitätskrankenhaus Hamburg-Eppendorf, Hamburg, Germany

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Jun Thorsteinsdottir Neurochirurgische Klinik und Poliklinik, LMU Klinikum, Munich, Germany

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Jochen Herms Center for Neuropathology and Prion Research, LMU Munich, Munich, Germany

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Günter Stalla Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität München, Munich, Germany
Medicover Neuroendocrinology, Munich, Germany

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Martin Reincke Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität München, Munich, Germany

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Marily Theodoropoulou Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität München, Munich, Germany

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bilateral adrenalectomy ( Ritzel et al. 2013 , Pivonello et al. 2015 , Tritos & Biller 2018 , Feelders et al. 2019 ). The somatostatin analogue pasireotide is the only pituitary-targeting pharmaceutical that is approved for the treatment of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-22-0088
Volume/Issue:
Volume 29: Issue 8
Open access
Thomas Cuny Aix-Marseille University, CNRS, CRN2M UMR7286, Marseille, France

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Caroline Zeiller Aix-Marseille University, CNRS, CRN2M UMR7286, Marseille, France

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Martin Bidlingmaier Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Klinikum der LMU, Munich, Germany

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Céline Défilles Aix-Marseille University, CNRS, CRN2M UMR7286, Marseille, France

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Catherine Roche APHM, Conception, Laboratory of Molecular Biology, Marseille, France

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Marie-Pierre Blanchard Aix-Marseille University, CNRS, CRN2M UMR7286, Marseille, France

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Marily Theodoropoulou Department of Endocrinology, Max Planck Institute of Psychiatry, Munich, Germany

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Thomas Graillon Aix-Marseille University, CNRS, CRN2M UMR7286, Marseille, France
APHM Timone, Department of Neurosurgery, Marseille, France

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Morgane Pertuit APHM, Conception, Laboratory of Molecular Biology, Marseille, France

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Dominique Figarella-Branger APHM Timone, Laboratory of Neuropathology and Aix-Marseille University, INSERM, CRO2 UMR911, Marseille, France

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Alain Enjalbert Aix-Marseille University, CNRS, CRN2M UMR7286, Marseille, France
APHM, Conception, Laboratory of Molecular Biology, Marseille, France

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Thierry Brue Aix-Marseille University, CNRS, CRN2M UMR7286, Marseille, France
APHM Conception, Department of Endocrinology, Marseille, France

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Anne Barlier Aix-Marseille University, CNRS, CRN2M UMR7286, Marseille, France
APHM, Conception, Laboratory of Molecular Biology, Marseille, France

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( Iwama et al. 2014 ). In light of the so-called Nelson’s syndrome secondary to bilateral adrenalectomy and abolition of the cortisol-induced negative feedback, the issue concerning the role of PEG in promoting growth of a residual GH-secreting tumor

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-16-0140
Volume/Issue:
Volume 23: Issue 7
Open access
Anna Angelousi Unit of Endocrinology, First Department of Internal Medicine, Laiko Hospital, National and Kapodistrian University of Athens, Athens, Greece

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Aimee R Hayes Neuroendocrine Tumour Unit, ENETS Centre of Excellence, Royal Free Hospital, London, UK

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Eleftherios Chatzellis Endocrinology Diabetes and Metabolism Department, 251 Hellenic Air Force and VA General Hospital, Athens, Greece

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Gregory A Kaltsas First Department of Propaedeutic Internal Medicine, Laiko Hospital, National & Kapodistrian University of Athens, Athens, Greece

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Ashley B Grossman Neuroendocrine Tumour Unit, ENETS Centre of Excellence, Royal Free Hospital, London, UK
Green Templeton College, University of Oxford, Oxford, UK
Centre for Endocrinology, Barts and the London School of Medicine, London, UK

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/or metyrapone. Surgical intervention with bilateral adrenalectomy is another option available to some patients ( Hayes & Grossman 2018 ). However, systemic therapy with tyrosine kinase inhibitors such as vandetanib offers a further management strategy for

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-21-0368
Volume/Issue:
Volume 29: Issue 7
Open access