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Dame Roma Mitchell Cancer Research Laboratories School of Medicine, University of Adelaide, Adelaide, South Australia 5000, Australia
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of androgen receptor signalling in breast cancer . Endocrine-Related Cancer 21 T161 – T181 . ( doi:10.1530/ERC-14-0243 ). Nelson AW Tilley WD Neal DE Carroll JS 2014 Oestrogen receptor β in prostate cancer: friend or foe? Endocrine
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cell functions. Dysregulation of sex hormone-receptor signalling occurs in the tumourigenesis of breast, endometrial, ovary, prostate and testis, where oestrogens, progestin and androgens have been shown to modulate the proliferation of epithelial cells
Division of Environmental Genetics and Molecular Toxicology, Division of Epidemiology and Biostatistics, Center for Environmental Genetics, Cancer Center, Department of Pathology, Department of Pathology and Laboratory Medicine, Department of Environmental Health
Division of Environmental Genetics and Molecular Toxicology, Division of Epidemiology and Biostatistics, Center for Environmental Genetics, Cancer Center, Department of Pathology, Department of Pathology and Laboratory Medicine, Department of Environmental Health
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Division of Environmental Genetics and Molecular Toxicology, Division of Epidemiology and Biostatistics, Center for Environmental Genetics, Cancer Center, Department of Pathology, Department of Pathology and Laboratory Medicine, Department of Environmental Health
Division of Environmental Genetics and Molecular Toxicology, Division of Epidemiology and Biostatistics, Center for Environmental Genetics, Cancer Center, Department of Pathology, Department of Pathology and Laboratory Medicine, Department of Environmental Health
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. Henderson BE Bernstein L Ross RK Depue RH Judd HL 1988 The early in utero oestrogen and testosterone environment of blacks and whites: potential effects on male offspring . British Journal of Cancer 57 216 – 218 . Ho SM Leung YK
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project that examined the role of oestrogen in the normal development of the prostate gland and found that oestrogen receptor was expressed by the stromal cells ( Tilley et al . 1989 ). I will always be indebted to Wayne Tilley for giving me the
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phosphorylation of EGFR and ERK1/2 and of the proliferative marker Ki67 ( Gee et al. 2004 ). These clinical observations were anticipated by studies with oestrogen receptor-positive (ER + ) MCF7 human breast cancer cells which showed that resistance to
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Breast Cancer. Journal of the National Cancer Institute 90 1601 –1608. Green S , Walter P, Kumar V, Krust A, Bornert JM, Argos P & Chambon P 1986 Human oestrogen receptor sDNA: sequence, expression and homology to v
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death ranging from 8 to 28%, depending on the type and duration of therapy, the age of the patient and the characteristics of the tumour ( Aebi et al . 2011 ). Tumours with detectable (≥1%) expression of oestrogen receptors (ER) and/or progesterone
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Oestrogen-receptor-positive breast cancer: towards bridging histopathological and molecular classifications . Journal of Clinical Pathology 62 6 – 12 . doi:10.1136/jcp.2008.059899 . Banu KS Govindarajulu P Aruldhas MM 2001 Testosterone and
Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK
Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore
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This intricate system, and disruptions therein, can have profound effects on human health ( Roenneberg & Merrow 2016 ). Circadian rhythms influence homeostasis and regulate a variety of integral hormones including insulin, glucagon, oestrogen and
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Conjugated equine oestrogen and breast cancer incidence and mortality in postmenopausal women with hysterectomy: extended follow-up of the Women's Health Initiative randomised placebo-controlled trial . Lancet Oncology 13 476 – 486 . ( doi:10.1016/S1470