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Introduction Prostate cancer is the most frequently diagnosed cancer and the second cause of cancer death in men in North America ( Siegel et al . 2013 ). In fact, one in eight men will be diagnosed with prostate cancer during his lifetime. At such
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Department of Periodontics and Oral Medicine, Department of Pathology, University of Michigan School of Dentistry, 1011 North University Avenue, Ann Arbor, Michigan 48109, USA
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Introduction Prostate cancer is the second most frequently diagnosed cancer and the sixth leading cause of cancer-related death in males worldwide, notwithstanding the improved early detection methods and therapeutic modalities ( Jemal et al . 2011
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Faculty of Medicine and Health Sciences, Department of Pharmacology, Cancer Biology, Department of International Health, Clinical Research Center, Department of Pharmacology, School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Nottingham LE12 5RD, UK
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Prostate cancer: the molecular mechanisms of carcinogenesis and the role of androgens Prostate cancer (PCa) is the most common malignancy affecting western men ( Ferlay et al . 2013 , Siegel et al . 2015 ), and it is estimated to account for more
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Introduction Prostate cancer (PC) is the most frequently diagnosed cancer in men, exceeded only by lung cancer as the leading cause of cancer-related mortality among men ( Ferlay et al. 2010 ). Despite recent advances in the field, effective
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Introduction: addressing problems with the clinical management of prostate cancer Prostate cancer (CaP) has a unique set of problems associated with its early detection, diagnosis and treatment that might be aided by the
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Department of Pathology, Arthritis and Tissue Degeneration Program, Laboratory of Molecular Biology, Department of Pathology, Department of Urology, NYU Cancer Institute, New York Harbor Healthcare System, Department of Urology, New York University School of Medicine, New York, NY, USA
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Department of Pathology, Arthritis and Tissue Degeneration Program, Laboratory of Molecular Biology, Department of Pathology, Department of Urology, NYU Cancer Institute, New York Harbor Healthcare System, Department of Urology, New York University School of Medicine, New York, NY, USA
Department of Pathology, Arthritis and Tissue Degeneration Program, Laboratory of Molecular Biology, Department of Pathology, Department of Urology, NYU Cancer Institute, New York Harbor Healthcare System, Department of Urology, New York University School of Medicine, New York, NY, USA
Department of Pathology, Arthritis and Tissue Degeneration Program, Laboratory of Molecular Biology, Department of Pathology, Department of Urology, NYU Cancer Institute, New York Harbor Healthcare System, Department of Urology, New York University School of Medicine, New York, NY, USA
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Introduction Prostate cancer (PCa) is the most common male-specific cancer in most western countries including the United States. An important cause of morbidity and mortality in PCa is skeletal metastasis; the pathogenesis of bone metastasis is
Department of Urology, Department of Oncology, Brady Urologic Institute
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Department of Urology, Department of Oncology, Brady Urologic Institute
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Department of Urology, Department of Oncology, Brady Urologic Institute
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Introduction Over the last several decades, there have been improvements in prostate cancer diagnosis and treatment primarily due to the diagnostic/prognostic use of prostate specific antigen, the advent of nerve sparing radical prostatectomy
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Introduction Prostate cancer is the most commonly diagnosed non-skin cancer among men in developed countries ( Jemal et al . 2008 ). In its early stages, prostate cancer cell growth is androgen dependent, and androgen deprivation therapies cause
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Introduction Prostate cancer (PCa) is the most common cancer diagnosed in men and is considered as one of the major causes of death in developed countries ( Siegel et al. 2015 ). It is highly prevalent in older men, with those over 65 years
Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
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Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
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Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
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Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
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Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
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Department of Obstetrics and Gynecology, Department of Pathology and Immunology, Department of Molecular and Cellular Biology, Baylor College of Medicine, Departments of Gynecologic Oncology and Cancer Biology, Department of Experimental Therapeutics, Center for RNA Interference and Non-Coding RNA, Department of Human Anatomy and Cell Science, Michael E DeBakey Veterans Affairs Medical Center, Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas 77030, USA
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Introduction Prostate cancer is the most common type of cancer in men in the United States and the second leading cause of cancer deaths. Androgens play a key role in prostate cancer initiation and progression and androgen ablation is initially