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Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK
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Introduction Prostate cancer (PCa) is the second most commonly diagnosed cancer and the fifth most common cause of death in men worldwide ( Sung et al. 2021 ). Although the aetiology of PCa is multifactorial, genomics is a key variable
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Introduction The treatment landscape of advanced prostate cancer continues to evolve. Drugs with varied mechanisms of action now being used in earlier disease settings, and patients are living longer with longer exposure to systemic therapies
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breast and prostate cancer: a Mendelian randomization study . International Journal of Epidemiology 48 1416 – 1424 . ( https://doi.org/10.1093/ije/dyy284 ) 30597039 Jiang X Ge T Chen CY 2021 The causal role of circulating vitamin D concentrations
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.2) 3 (5) 3 (14) Hispanic 3 (3.6) 3 (5) 0 (0) Cancer type, n (%) Melanoma 54 (65) 42 (68) 9 (43) Prostate cancer 16 (19.3) 11 (18) 4 (19) Renal cell carcinoma 8 (9.6) 5 (8) 3 (14
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with differential expression in small cell lung cancer cell lines. Structural analysis of the protein revealed it was highly homologous with the proteins Delta , Serrate and Notch from Drosophila melanogaster and it was termed ‘human Delta