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Ravi Kumar Dutta, Peter Söderkvist, and Oliver Gimm

driving gene rather than a passenger gene. The expression of ARMC5 was downregulated in the mutated cells when compared with nonmutated APAs. Developmental abnormalities of the adrenal were found in mice and zebrafish harboring a loss

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Chen-Hsin Liao, Shih-Chi Yeh, Ya-Hui Huang, Ruey-Nan Chen, Ming-Ming Tsai, Wei-Jan Chen, Hsiang-Cheng Chi, Pei-Ju Tai, Chia-Jung Liao, Sheng-Ming Wu, Wan-Li Cheng, Li-Mei Pai, and Kwang-Huei Lin

) is a member of the mindin–F-spondin family of extracellular matrix proteins. This family includes rat F-spondin and mindin, zebrafish mindin 1 and mindin 2, and Drosophila melanogaster M-spondin ( He et al . 2004 ). All members of the mindin

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Hongyu Chen, Dan Liu, Zhengyan Yang, Limin Sun, Que Deng, Shuo Yang, Lu Qian, Liang Guo, Ming Yu, Meiru Hu, Ming Shi, and Ning Guo

Notch function in the vasculature: insights from zebrafish, mouse and man . BioEssays 26 225 – 234 . ( doi:10.1002/bies.20004 ). Shi M Liu D Duan H Han C Wei B Qian L Chen C Guo L Hu M Yu M 2010 Catecholamine up

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Takako Araki, Ning-Ai Liu, Yukiko Tone, Daniel Cuevas-Ramos, Roy Heltsley, Masahide Tone, and Shlomo Melmed

H Ben-Shlomo A Wawrowsky K Fan XM Lin S Melmed S 2011 Targeting zebrafish and murine pituitary corticotroph tumors with a cyclin-dependent kinase (CDK) inhibitor . PNAS 108 8414 – 8419 . ( doi:10.1073/pnas.1018091108

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Pauline Croisé, Sébastien Houy, Mathieu Gand, Joël Lanoix, Valérie Calco, Petra Tóth, Laurent Brunaud, Sandra Lomazzi, Eustache Paramithiotis, Daniel Chelsky, Stéphane Ory, and Stéphane Gasman

Liu XJ Liu L Spitsbergen JM Gong Z Low BC 2014 Crosstalk of Ras and Rho: Activation of RhoA abates Kras-induced liver tumorigenesis in transgenic zebrafish models . Oncogene 33 2717 – 2727 . ( doi:10

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Sara Molatore, Andrea Kügler, Martin Irmler, Tobias Wiedemann, Frauke Neff, Annette Feuchtinger, Johannes Beckers, Mercedes Robledo, Federico Roncaroli, and Natalia S Pellegata

may be used to test novel antitumor agents, but they do not recapitulate the tumor microenvironment and the interactions between stroma and cancer cells. Alternative models such as Drosophila , chick embryo chorioallantoic membrane and zebrafish are

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Luke A Selth, Wayne D Tilley, and Lisa M Butler

microRNA spectrum in 12 body fluids . Clinical Chemistry 56 1733 – 1741 . doi:10.1373/clinchem.2010.147405 . Wienholds E Koudijs MJ van Eeden FJ Cuppen E Plasterk RH 2003 The microRNA-producing enzyme Dicer1 is essential for zebrafish

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Catherine Zabkiewicz, Jeyna Resaul, Rachel Hargest, Wen Guo Jiang, and Lin Ye

:10.1016/j.cytogfr.2015.11.009 ) 10.1016/j.cytogfr.2015.11.009 de Boeck M Cui C Mulder AA Jost CR Ikeno S Ten Dijke P 2016 Smad6 determines BMP-regulated invasive behaviour of breast cancer cells in a zebrafish xenograft

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María Gutiérrez-Salmerón, Silvia Rocío Lucena, Ana Chocarro-Calvo, José Manuel García-Martínez, Rosa M Martín Orozco, and Custodia García-Jiménez

the use of in vivo models which are often difficult to interpret. In vivo models allow the study of interactions between different tissues and organs. Non-mammalian experimental organisms with a short life cycle (Zebrafish, C. elegans and

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Eric Glasgow and Lopa Mishra

known as the activin response factor (ARF) that also contains Smad2 and Smad4. Smad2 interacts directly with FAST-1 recruiting Smad4 to the complex. Similarly, in both X. laevis and zebrafish, the activin-inducible promoter of the LIM