Search Results

You are looking at 81 - 90 of 201 items for :

  • "paraganglioma" x
  • All content x
Clear All
Free access

Trisha Dwight, Aidan Flynn, Kaushalya Amarasinghe, Diana E Benn, Richard Lupat, Jason Li, Daniel L Cameron, Annette Hogg, Shiva Balachander, Ida L M Candiloro, Stephen Q Wong, Bruce G Robinson, Anthony T Papenfuss, Anthony J Gill, Alexander Dobrovic, Rodney J Hicks, Roderick J Clifton-Bligh, and Richard W Tothill

Introduction Pheochromocytomas (PC) and paragangliomas (PGLs) are neuroendocrine tumors derived from neural crest cells of the sympathetic and parasympathetic nervous system – PCs arising in the adrenal medulla and PGLs in paraganglia outside

Free access

Martin Gotthardt, Martin P Béhé, Julia Grass, Artur Bauhofer, Anja Rinke, Meike L Schipper, Marc Kalinowski, Rudolf Arnold, Wim J G Oyen, and Thomas M Behr

scintigraphy and functional status/localisation of the tumours was determined in the same manner (paragangliomas were excluded from this evaluation). Results Patients From July 2001 to July 2003, 122 GRS and SRS

Free access

Francien H van Nederveen, Esther Korpershoek, Ronald J deLeeuw, Albert A Verhofstad, Jacques W Lenders, Winand N M Dinjens, Wan L Lam, and Ronald R de Krijger

Introduction Pheochromocytomas (PCC) are rare neuro-endocrine tumors arising from the adrenal medulla. Similar tumors arise from extra-adrenal chromaffin tissues, and are now referred to as sympathetic paragangliomas (PGLs; Baguet et al . 2004

Free access

Nele Garbrecht, Martin Anlauf, Anja Schmitt, Tobias Henopp, Bence Sipos, Andreas Raffel, Claus F Eisenberger, Wolfram T Knoefel, Marianne Pavel, Christian Fottner, Thomas J Musholt, Anja Rinke, Rudolf Arnold, Uta Berndt, Ursula Plöckinger, Bertram Wiedenmann, Holger Moch, Philipp U Heitz, Paul Komminoth, Aurel Perren, and Günter Klöppel

) syndromes. Somatostatin expression was also found in gangliocytic paragangliomas (GCPGs; Hamid et al . 1986 , Tischler et al . 2004 ). All of these tumors are uncommon. Our knowledge of their incidence, histopathology, biology, hereditary background, and

Free access

A Perren, S Schmid, T Locher, P Saremaslani, C Bonvin, P U Heitz, and P Komminoth

tumors including pheochromocytomas (PCCs), paragangliomas (PGLs) and medullary thyorid carcinomas (MTCs) evolve from neural-crest-derived cells ( Pasini et al. 1996 ). Secondly, on a molecular genetic level, activation of tyrosine kinases ( Ret

Open access

Tiantian Liu, Taylor C Brown, C Christofer Juhlin, Adam Andreasson, Na Wang, Martin Bäckdahl, James M Healy, Manju L Prasad, Reju Korah, Tobias Carling, Dawei Xu, and Catharina Larsson

pheochromocytoma (PCC) and an adrenocortical carcinoma (ACC). Pheochromocytomas (PCC) and abdominal paragangliomas (PGL) are typically catecholamine-producing tumors, originating from chromaffin cells in the paraganglia inside or outside the adrenal medulla ( Elder

Free access

Elena Rapizzi, Rossella Fucci, Elisa Giannoni, Letizia Canu, Susan Richter, Paolo Cirri, and Massimo Mannelli

paragangliomas (PGL), which harbor mutations in the tricarboxylic acid cycle enzymes, such as fumarate hydratase (FH) ( Castro-Vega et al . 2014 ) and succinate dehydrogenase (SDH) ( Baysal et al . 2000 , and for recent reviews, see Dahia (2014) and Martucci

Free access

Graeme Eisenhofer, Karel Pacak, Thanh-Truc Huynh, Nan Qin, Gennady Bratslavsky, W Marston Linehan, Massimo Mannelli, Peter Friberg, Stefan K Grebe, Henri J Timmers, Stefan R Bornstein, and Jacques W M Lenders

Introduction Phaeochromocytomas and paragangliomas (PPGLs) are heterogeneous tumours with highly variable signs and symptoms and diverse clinical presentations ( Manger 2009 ). Much of the heterogeneity is due to wide-ranging variations in the types

Free access

Thomas G Papathomas, Lindsey Oudijk, Ellen C Zwarthoff, Edward Post, Floor A Duijkers, Max M van Noesel, Leo J Hofland, Patrick J Pollard, Eamonn R Maher, David F Restuccia, Richard A Feelders, Gaston J H Franssen, Henri J Timmers, Stefan Sleijfer, Wouter W de Herder, Ronald R de Krijger, Winand N M Dinjens, and Esther Korpershoek

pheochromocytomas (PCCs) and paragangliomas (PGLs) ( Vinagre et al . 2013 , Liu et al . 2014 ). In the current study, we examined the presence of these mutations in tumor types originating from the adrenal gland and extra-adrenal paraganglia including ACCs, PCCs

Free access

Vanessa D'Antongiovanni, Serena Martinelli, Susan Richter, Letizia Canu, Daniele Guasti, Tommaso Mello, Paolo Romagnoli, Karel Pacak, Graeme Eisenhofer, Massimo Mannelli, and Elena Rapizzi

Introduction Germline mutations in nuclear genes encoding succinate dehydrogenase (SDH), or mitochondrial complex II, are related with the occurrence of pheochromocytoma/paraganglioma (Pheo/PGL). SDH is a tetrameric protein composed by two