Search Results
Igryl S Cordero-Hernandez
Igryl S Cordero-Hernandez
Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Search for other papers by Igryl S Cordero-Hernandez in
Google Scholar
PubMed
Search for other papers by Igryl S Cordero-Hernandez in
Google Scholar
PubMed
Alicia C Ross
Alicia C Ross
Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Search for other papers by Alicia C Ross in
Google Scholar
PubMed
Search for other papers by Alicia C Ross in
Google Scholar
PubMed
Arvind Dasari
Arvind Dasari
Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Search for other papers by Arvind Dasari in
Google Scholar
PubMed
Search for other papers by Arvind Dasari in
Google Scholar
PubMed
Daniel M Halperin
Daniel M Halperin
Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Search for other papers by Daniel M Halperin in
Google Scholar
PubMed
Search for other papers by Daniel M Halperin in
Google Scholar
PubMed
Beth Chasen
Beth Chasen
Department of Nuclear Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Search for other papers by Beth Chasen in
Google Scholar
PubMed
Search for other papers by Beth Chasen in
Google Scholar
PubMed
James C Yao
James C Yao
Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Search for other papers by James C Yao in
Google Scholar
PubMed
Search for other papers by James C Yao in
Google Scholar
PubMed
). In the gastrointestinal and pancreatobiliary tracts, NEN are divided into well differentiated neuroendocrine tumors (NET) and poorly differentiated neuroendocrine carcinomas (NEC). NET are classified as G1, G2, and G3 based on tumor proliferation
J Hadoux
J Hadoux
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by J Hadoux in
Google Scholar
PubMed
Search for other papers by J Hadoux in
Google Scholar
PubMed
D Malka
D Malka
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by D Malka in
Google Scholar
PubMed
Search for other papers by D Malka in
Google Scholar
PubMed
D Planchard
D Planchard
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by D Planchard in
Google Scholar
PubMed
Search for other papers by D Planchard in
Google Scholar
PubMed
J Y Scoazec
J Y Scoazec
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by J Y Scoazec in
Google Scholar
PubMed
Search for other papers by J Y Scoazec in
Google Scholar
PubMed
C Caramella
C Caramella
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by C Caramella in
Google Scholar
PubMed
Search for other papers by C Caramella in
Google Scholar
PubMed
J Guigay
J Guigay
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by J Guigay in
Google Scholar
PubMed
Search for other papers by J Guigay in
Google Scholar
PubMed
V Boige
V Boige
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by V Boige in
Google Scholar
PubMed
Search for other papers by V Boige in
Google Scholar
PubMed
S Leboulleux
S Leboulleux
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by S Leboulleux in
Google Scholar
PubMed
Search for other papers by S Leboulleux in
Google Scholar
PubMed
P Burtin
P Burtin
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by P Burtin in
Google Scholar
PubMed
Search for other papers by P Burtin in
Google Scholar
PubMed
A Berdelou
A Berdelou
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by A Berdelou in
Google Scholar
PubMed
Search for other papers by A Berdelou in
Google Scholar
PubMed
Y Loriot
Y Loriot
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by Y Loriot in
Google Scholar
PubMed
Search for other papers by Y Loriot in
Google Scholar
PubMed
P Duvillard
P Duvillard
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by P Duvillard in
Google Scholar
PubMed
Search for other papers by P Duvillard in
Google Scholar
PubMed
C N Chougnet
C N Chougnet
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by C N Chougnet in
Google Scholar
PubMed
Search for other papers by C N Chougnet in
Google Scholar
PubMed
D Déandréis
D Déandréis
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by D Déandréis in
Google Scholar
PubMed
Search for other papers by D Déandréis in
Google Scholar
PubMed
M Schlumberger
M Schlumberger
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by M Schlumberger in
Google Scholar
PubMed
Search for other papers by M Schlumberger in
Google Scholar
PubMed
I Borget
I Borget
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by I Borget in
Google Scholar
PubMed
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by I Borget in
Google Scholar
PubMed
M Ducreux
M Ducreux
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by M Ducreux in
Google Scholar
PubMed
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by M Ducreux in
Google Scholar
PubMed
E Baudin
E Baudin
Departments of Nuclear Medicine and Endocrine Tumors, Digestive Oncology, Medical Oncology (Thoracic Group), Pathology, Radiology, Centre Antoine Lacassagne, Department of Urologic Oncology, Department of Endocrinology, Department of Biostatistics and Epidemiology, Faculté de Médecine, Gustave Roussy, 114 Rue Edouard Vaillant, F-94800 Villejuif Cedex, France
Search for other papers by E Baudin in
Google Scholar
PubMed
Search for other papers by E Baudin in
Google Scholar
PubMed
exhibit a very heterogeneous prognosis. Pathological differentiation or grading and TNM stage are the most important prognostic factors ( Baudin 2007 ). Poorly differentiated neuroendocrine carcinomas (NECs) are characterized by a poorer outcome when
Julien Hadoux
Julien Hadoux
Oncologie Endocrinienne, Département d’Imagerie, Gustave Roussy, Villejuif, France
Search for other papers by Julien Hadoux in
Google Scholar
PubMed
Search for other papers by Julien Hadoux in
Google Scholar
PubMed
Thomas Walter
Thomas Walter
Service d’Oncologie, ENETS Centre of Excellence, Hospices Civils de Lyon et Université de Lyon, Lyon, France
Search for other papers by Thomas Walter in
Google Scholar
PubMed
Search for other papers by Thomas Walter in
Google Scholar
PubMed
Christina Kanaan
Christina Kanaan
Service de Pathologie, Département de Biologie et Pathologie Médicale, Gustave Roussy, Villejuif, France
Search for other papers by Christina Kanaan in
Google Scholar
PubMed
Search for other papers by Christina Kanaan in
Google Scholar
PubMed
Ségolène Hescot
Ségolène Hescot
Département d’Oncologie, Institut Curie, Paris, France
Search for other papers by Ségolène Hescot in
Google Scholar
PubMed
Search for other papers by Ségolène Hescot in
Google Scholar
PubMed
Vincent Hautefeuille
Vincent Hautefeuille
Service d’Hépato-gastro-entérologie et Cancérologie Digestive, CHU Amiens Picardie, Amiens, France
Search for other papers by Vincent Hautefeuille in
Google Scholar
PubMed
Search for other papers by Vincent Hautefeuille in
Google Scholar
PubMed
Marine Perrier
Marine Perrier
Département d’Hépato-gastro-entérologie, CHU de Reims, Reims, France
Search for other papers by Marine Perrier in
Google Scholar
PubMed
Search for other papers by Marine Perrier in
Google Scholar
PubMed
Igor Tauveron
Igor Tauveron
Service d'Endocrinologie, Diabétologie et Maladies Métaboliques, CHU Clermont-Ferrand, Clermont-Ferrand, France
Laboratoire GReD, Université Clermont Auvergne, Clermont-Ferrand, France
Search for other papers by Igor Tauveron in
Google Scholar
PubMed
Laboratoire GReD, Université Clermont Auvergne, Clermont-Ferrand, France
Search for other papers by Igor Tauveron in
Google Scholar
PubMed
Sandrine Laboureau
Sandrine Laboureau
Département d’Endocrinologie-Diabétologie-Nutrition, CHU d’Angers, Angers Cedex 9, France
Search for other papers by Sandrine Laboureau in
Google Scholar
PubMed
Search for other papers by Sandrine Laboureau in
Google Scholar
PubMed
Christine Do Cao
Christine Do Cao
CHU de Lille, Service d’Endocrinologie, Lille, France
Search for other papers by Christine Do Cao in
Google Scholar
PubMed
Search for other papers by Christine Do Cao in
Google Scholar
PubMed
Caroline Petorin
Caroline Petorin
CHU Clermont-Ferrand, Service de Chirurgie Digestive et Hépatobiliaire, Clermont-Ferrand, France
Search for other papers by Caroline Petorin in
Google Scholar
PubMed
Search for other papers by Caroline Petorin in
Google Scholar
PubMed
Odile Blanchet
Odile Blanchet
CRB, CHU d’Angers, Angers Cedex 9, France
Search for other papers by Odile Blanchet in
Google Scholar
PubMed
Search for other papers by Odile Blanchet in
Google Scholar
PubMed
Matthieu Faron
Matthieu Faron
Département de Chirurgie, Gustave Roussy, Villejuif, France
Search for other papers by Matthieu Faron in
Google Scholar
PubMed
Search for other papers by Matthieu Faron in
Google Scholar
PubMed
Emmanuelle Leteurtre
Emmanuelle Leteurtre
CANTHER - Cancer Heterogeneity Plasticity and Resistance to Therapies, Université de Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277, Lille, France
Search for other papers by Emmanuelle Leteurtre in
Google Scholar
PubMed
Search for other papers by Emmanuelle Leteurtre in
Google Scholar
PubMed
Marie-Christine Rousselet
Marie-Christine Rousselet
Département de Pathologie, CHU d’Angers, Angers Cedex 9, France
Search for other papers by Marie-Christine Rousselet in
Google Scholar
PubMed
Search for other papers by Marie-Christine Rousselet in
Google Scholar
PubMed
Juliette Joubert Zakeyh
Juliette Joubert Zakeyh
Laboratoire d’Anatomie Pathologique, CHU Clermont-Ferrand, Clermont-Ferrand, France
Search for other papers by Juliette Joubert Zakeyh in
Google Scholar
PubMed
Search for other papers by Juliette Joubert Zakeyh in
Google Scholar
PubMed
Aude Marchal
Aude Marchal
Service d’Anatomo-Pathologie, CHU Reims, Reims, France
Search for other papers by Aude Marchal in
Google Scholar
PubMed
Search for other papers by Aude Marchal in
Google Scholar
PubMed
Denis Chatelain
Denis Chatelain
Service d’Anatomo-Pathologie, CHU Amiens, Amiens, France
Search for other papers by Denis Chatelain in
Google Scholar
PubMed
Search for other papers by Denis Chatelain in
Google Scholar
PubMed
Clément Beaulaton
Clément Beaulaton
Service d’Anatomo-Pathologie, Institut Curie, Paris, France
Search for other papers by Clément Beaulaton in
Google Scholar
PubMed
Search for other papers by Clément Beaulaton in
Google Scholar
PubMed
Valérie Hervieu
Valérie Hervieu
Service d’Anatomo-Pathologie, ENETS Centre of Excellence, Hospices Civils de Lyon et Université de Lyon, Lyon, France
Search for other papers by Valérie Hervieu in
Google Scholar
PubMed
Search for other papers by Valérie Hervieu in
Google Scholar
PubMed
Catherine Lombard-Bohas
Catherine Lombard-Bohas
Service d’Oncologie, ENETS Centre of Excellence, Hospices Civils de Lyon et Université de Lyon, Lyon, France
Search for other papers by Catherine Lombard-Bohas in
Google Scholar
PubMed
Search for other papers by Catherine Lombard-Bohas in
Google Scholar
PubMed
Michel Ducreux
Michel Ducreux
Service d’Oncologie Digestive, Département de Médecine, Gustave Roussy, Villejuif, France
Faculté de Médecine, Université Paris Saclay, Le Kremlin-Bicêtre, France
Search for other papers by Michel Ducreux in
Google Scholar
PubMed
Faculté de Médecine, Université Paris Saclay, Le Kremlin-Bicêtre, France
Search for other papers by Michel Ducreux in
Google Scholar
PubMed
Jean-Yves Scoazec
Jean-Yves Scoazec
Service de Pathologie, Département de Biologie et Pathologie Médicale, Gustave Roussy, Villejuif, France
Faculté de Médecine, Université Paris Saclay, Le Kremlin-Bicêtre, France
Search for other papers by Jean-Yves Scoazec in
Google Scholar
PubMed
Faculté de Médecine, Université Paris Saclay, Le Kremlin-Bicêtre, France
Search for other papers by Jean-Yves Scoazec in
Google Scholar
PubMed
Eric Baudin
Eric Baudin
Oncologie Endocrinienne, Département d’Imagerie, Gustave Roussy, Villejuif, France
Search for other papers by Eric Baudin in
Google Scholar
PubMed
Search for other papers by Eric Baudin in
Google Scholar
PubMed
the Groupe d’Etude des Tumeurs Endocrines (GTE)
the Groupe d’Etude des Tumeurs Endocrines (GTE)
Search for other papers by the Groupe d’Etude des Tumeurs Endocrines (GTE) in
Google Scholar
PubMed
Search for other papers by the Groupe d’Etude des Tumeurs Endocrines (GTE) in
Google Scholar
PubMed
the ENDOCAN-RENATEN network
the ENDOCAN-RENATEN network
Search for other papers by the ENDOCAN-RENATEN network in
Google Scholar
PubMed
Search for other papers by the ENDOCAN-RENATEN network in
Google Scholar
PubMed
Introduction Neuroendocrine carcinomas (NECs) are highly malignant diseases, which can occur in all organs and are defined by a poorly differentiated morphology and high proliferative capacities testified by a high Ki-67 index ( Rindi et al
Atsuko Kasajima
Atsuko Kasajima
Department of Pathology, Technical University Munich, Munich, Germany
Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan
Search for other papers by Atsuko Kasajima in
Google Scholar
PubMed
Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan
Search for other papers by Atsuko Kasajima in
Google Scholar
PubMed
Yuichi Ishikawa
Yuichi Ishikawa
Pathology Department, The Cancer Institute Hospital of JFCR, Tokyo, Japan
Search for other papers by Yuichi Ishikawa in
Google Scholar
PubMed
Search for other papers by Yuichi Ishikawa in
Google Scholar
PubMed
Ayaka Iwata
Ayaka Iwata
Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan
Search for other papers by Ayaka Iwata in
Google Scholar
PubMed
Search for other papers by Ayaka Iwata in
Google Scholar
PubMed
Katja Steiger
Katja Steiger
Department of Pathology, Technical University Munich, Munich, Germany
Search for other papers by Katja Steiger in
Google Scholar
PubMed
Search for other papers by Katja Steiger in
Google Scholar
PubMed
Naomi Oka
Naomi Oka
Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan
National Hospital Organization, Sendai Medical Center, Sendai, Japan
Search for other papers by Naomi Oka in
Google Scholar
PubMed
National Hospital Organization, Sendai Medical Center, Sendai, Japan
Search for other papers by Naomi Oka in
Google Scholar
PubMed
Hirotaka Ishida
Hirotaka Ishida
Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan
Search for other papers by Hirotaka Ishida in
Google Scholar
PubMed
Search for other papers by Hirotaka Ishida in
Google Scholar
PubMed
Akira Sakurada
Akira Sakurada
Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University Graduate School of Medicine, Sendai, Japan
Search for other papers by Akira Sakurada in
Google Scholar
PubMed
Search for other papers by Akira Sakurada in
Google Scholar
PubMed
Hiroyoshi Suzuki
Hiroyoshi Suzuki
National Hospital Organization, Sendai Medical Center, Sendai, Japan
Search for other papers by Hiroyoshi Suzuki in
Google Scholar
PubMed
Search for other papers by Hiroyoshi Suzuki in
Google Scholar
PubMed
Toru Kameya
Toru Kameya
Division of Pathology, Shizuoka Cancer Center Hospital and Research Institute, Sizuoka, Japan
Search for other papers by Toru Kameya in
Google Scholar
PubMed
Search for other papers by Toru Kameya in
Google Scholar
PubMed
Björn Konukiewitz
Björn Konukiewitz
Department of Pathology, Technical University Munich, Munich, Germany
Search for other papers by Björn Konukiewitz in
Google Scholar
PubMed
Search for other papers by Björn Konukiewitz in
Google Scholar
PubMed
Günter Klöppel
Günter Klöppel
Department of Pathology, Technical University Munich, Munich, Germany
Search for other papers by Günter Klöppel in
Google Scholar
PubMed
Search for other papers by Günter Klöppel in
Google Scholar
PubMed
Yoshinori Okada
Yoshinori Okada
Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University Graduate School of Medicine, Sendai, Japan
Search for other papers by Yoshinori Okada in
Google Scholar
PubMed
Search for other papers by Yoshinori Okada in
Google Scholar
PubMed
Hironobu Sasano
Hironobu Sasano
Department of Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan
Search for other papers by Hironobu Sasano in
Google Scholar
PubMed
Search for other papers by Hironobu Sasano in
Google Scholar
PubMed
Wilko Weichert
Wilko Weichert
Department of Pathology, Technical University Munich, Munich, Germany
Member of the German Cancer Consortium (DKTK)
Search for other papers by Wilko Weichert in
Google Scholar
PubMed
Member of the German Cancer Consortium (DKTK)
Search for other papers by Wilko Weichert in
Google Scholar
PubMed
Introduction Pulmonary neuroendocrine tumors, as defined in the 2015 classification of the World Health Organization (WHO), comprise three different types; carcinoid tumors, large cell neuroendocrine carcinomas (LCNEC) and small-cell lung
Carmine Valenza
Carmine Valenza
Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Via Ripamonti, Milan, Italy
Department of Oncology and Hemato-Oncology (DIPO), University of Milan, Milan, Italy
Search for other papers by Carmine Valenza in
Google Scholar
PubMed
Department of Oncology and Hemato-Oncology (DIPO), University of Milan, Milan, Italy
Search for other papers by Carmine Valenza in
Google Scholar
PubMed
Francesca Spada
Francesca Spada
Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, IEO, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Francesca Spada in
Google Scholar
PubMed
Search for other papers by Francesca Spada in
Google Scholar
PubMed
Francesco Multinu
Francesco Multinu
Division of Gynecologic Surgery, European Institute of Oncology, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Francesco Multinu in
Google Scholar
PubMed
Search for other papers by Francesco Multinu in
Google Scholar
PubMed
Lavinia Benini
Lavinia Benini
Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, IEO, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Lavinia Benini in
Google Scholar
PubMed
Search for other papers by Lavinia Benini in
Google Scholar
PubMed
Michele Borghesani
Michele Borghesani
Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, IEO, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Michele Borghesani in
Google Scholar
PubMed
Search for other papers by Michele Borghesani in
Google Scholar
PubMed
Laura Algeri
Laura Algeri
Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, IEO, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Laura Algeri in
Google Scholar
PubMed
Search for other papers by Laura Algeri in
Google Scholar
PubMed
Manila Rubino
Manila Rubino
Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, IEO, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Manila Rubino in
Google Scholar
PubMed
Search for other papers by Manila Rubino in
Google Scholar
PubMed
Eleonora Pisa
Eleonora Pisa
Division of Pathology and Laboratory Medicine, European Institute of Oncology, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Eleonora Pisa in
Google Scholar
PubMed
Search for other papers by Eleonora Pisa in
Google Scholar
PubMed
Lorenzo Gervaso
Lorenzo Gervaso
Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, IEO, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Lorenzo Gervaso in
Google Scholar
PubMed
Search for other papers by Lorenzo Gervaso in
Google Scholar
PubMed
Chiara Alessandra Cella
Chiara Alessandra Cella
Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, IEO, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Chiara Alessandra Cella in
Google Scholar
PubMed
Search for other papers by Chiara Alessandra Cella in
Google Scholar
PubMed
Silvestro Carinelli
Silvestro Carinelli
Division of Pathology and Laboratory Medicine, European Institute of Oncology, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Silvestro Carinelli in
Google Scholar
PubMed
Search for other papers by Silvestro Carinelli in
Google Scholar
PubMed
Simone Bruni
Simone Bruni
Division of Gynecologic Surgery, European Institute of Oncology, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Simone Bruni in
Google Scholar
PubMed
Search for other papers by Simone Bruni in
Google Scholar
PubMed
Gabriella Schivardi
Gabriella Schivardi
Division of Gynecologic Surgery, European Institute of Oncology, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Gabriella Schivardi in
Google Scholar
PubMed
Search for other papers by Gabriella Schivardi in
Google Scholar
PubMed
Giuseppe Curigliano
Giuseppe Curigliano
Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Via Ripamonti, Milan, Italy
Department of Oncology and Hemato-Oncology (DIPO), University of Milan, Milan, Italy
Search for other papers by Giuseppe Curigliano in
Google Scholar
PubMed
Department of Oncology and Hemato-Oncology (DIPO), University of Milan, Milan, Italy
Search for other papers by Giuseppe Curigliano in
Google Scholar
PubMed
Vanna Zanagnolo
Vanna Zanagnolo
Division of Gynecologic Surgery, European Institute of Oncology, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Vanna Zanagnolo in
Google Scholar
PubMed
Search for other papers by Vanna Zanagnolo in
Google Scholar
PubMed
Giovanni Aletti
Giovanni Aletti
Department of Oncology and Hemato-Oncology (DIPO), University of Milan, Milan, Italy
Division of Gynecologic Surgery, European Institute of Oncology, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Giovanni Aletti in
Google Scholar
PubMed
Division of Gynecologic Surgery, European Institute of Oncology, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Giovanni Aletti in
Google Scholar
PubMed
Nicoletta Colombo
Nicoletta Colombo
Division of Gynecologic Oncology, European Institute of Oncology, IRCCS, Via Ripamonti, Milan, Italy
Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy
Search for other papers by Nicoletta Colombo in
Google Scholar
PubMed
Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy
Search for other papers by Nicoletta Colombo in
Google Scholar
PubMed
Nicola Fazio
Nicola Fazio
Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, IEO, IRCCS, Via Ripamonti, Milan, Italy
Search for other papers by Nicola Fazio in
Google Scholar
PubMed
Search for other papers by Nicola Fazio in
Google Scholar
PubMed
Introduction High-grade neuroendocrine carcinoma of the cervix (NECC) is a rare subtype of invasive cervical carcinoma, accounting for 1.4% of all cases of cervical carcinoma and displaying an extremely aggressive biological behavior, with a
Jennifer R Eads
Jennifer R Eads
Division of Hematology and Oncology, Abramson Cancer Center, University of Pennsylvania, Pennsylvania, USA
Search for other papers by Jennifer R Eads in
Google Scholar
PubMed
Search for other papers by Jennifer R Eads in
Google Scholar
PubMed
Thorvardur R Halfdanarson
Thorvardur R Halfdanarson
Division of Medical Oncology, Mayo Clinic Cancer Center, Rochester, Minnesota, USA
Search for other papers by Thorvardur R Halfdanarson in
Google Scholar
PubMed
Search for other papers by Thorvardur R Halfdanarson in
Google Scholar
PubMed
Tim Asmis
Tim Asmis
Division of Medical Oncology, University of Ottawa, Ottawa, Ontario, Canada
Search for other papers by Tim Asmis in
Google Scholar
PubMed
Search for other papers by Tim Asmis in
Google Scholar
PubMed
Andrew M Bellizzi
Andrew M Bellizzi
Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA
Search for other papers by Andrew M Bellizzi in
Google Scholar
PubMed
Search for other papers by Andrew M Bellizzi in
Google Scholar
PubMed
Emily K Bergsland
Emily K Bergsland
Department of Medicine, University of California, San Francisco, California, USA
Search for other papers by Emily K Bergsland in
Google Scholar
PubMed
Search for other papers by Emily K Bergsland in
Google Scholar
PubMed
Arvind Dasari
Arvind Dasari
Division of Gastrointestinal Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Search for other papers by Arvind Dasari in
Google Scholar
PubMed
Search for other papers by Arvind Dasari in
Google Scholar
PubMed
Ghassan El-Haddad
Ghassan El-Haddad
Department of Diagnostic Imaging and Interventional Radiology, Moffitt Cancer Center and Research Institute, Tampa, Florida, USA
Search for other papers by Ghassan El-Haddad in
Google Scholar
PubMed
Search for other papers by Ghassan El-Haddad in
Google Scholar
PubMed
Michael Frumovitz
Michael Frumovitz
Division of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Search for other papers by Michael Frumovitz in
Google Scholar
PubMed
Search for other papers by Michael Frumovitz in
Google Scholar
PubMed
Joshua Meyer
Joshua Meyer
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
Search for other papers by Joshua Meyer in
Google Scholar
PubMed
Search for other papers by Joshua Meyer in
Google Scholar
PubMed
Erik Mittra
Erik Mittra
Division of Molecular Imaging and Therapy, Oregon Health & Science University, Portland, Oregon, USA
Search for other papers by Erik Mittra in
Google Scholar
PubMed
Search for other papers by Erik Mittra in
Google Scholar
PubMed
Sten Myrehaug
Sten Myrehaug
Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Search for other papers by Sten Myrehaug in
Google Scholar
PubMed
Search for other papers by Sten Myrehaug in
Google Scholar
PubMed
Eric Nakakura
Eric Nakakura
Department of Surgery, University of California, San Francisco, California, USA
Search for other papers by Eric Nakakura in
Google Scholar
PubMed
Search for other papers by Eric Nakakura in
Google Scholar
PubMed
Nitya Raj
Nitya Raj
Department of Medicine, Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Search for other papers by Nitya Raj in
Google Scholar
PubMed
Search for other papers by Nitya Raj in
Google Scholar
PubMed
Heloisa P Soares
Heloisa P Soares
Division of Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, Salt Lake City, Utah, USA
Search for other papers by Heloisa P Soares in
Google Scholar
PubMed
Search for other papers by Heloisa P Soares in
Google Scholar
PubMed
Brian Untch
Brian Untch
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Search for other papers by Brian Untch in
Google Scholar
PubMed
Search for other papers by Brian Untch in
Google Scholar
PubMed
Namrata Vijayvergia
Namrata Vijayvergia
Department of Hematology and Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA
Search for other papers by Namrata Vijayvergia in
Google Scholar
PubMed
Search for other papers by Namrata Vijayvergia in
Google Scholar
PubMed
Jennifer A Chan
Jennifer A Chan
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA
Search for other papers by Jennifer A Chan in
Google Scholar
PubMed
Search for other papers by Jennifer A Chan in
Google Scholar
PubMed
-differentiated high-grade neuroendocrine tumors (G3 NET) and poorly differentiated high-grade neuroendocrine carcinomas (NECs). Most available literature does not account for this subcategorization and as a result, much of the management of high-grade NENs is based on
Nora Sahnane
Nora Sahnane
Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy
Search for other papers by Nora Sahnane in
Google Scholar
PubMed
Search for other papers by Nora Sahnane in
Google Scholar
PubMed
Daniela Furlan
Daniela Furlan
Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy
Search for other papers by Daniela Furlan in
Google Scholar
PubMed
Search for other papers by Daniela Furlan in
Google Scholar
PubMed
Matilde Monti
Matilde Monti
Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy
Search for other papers by Matilde Monti in
Google Scholar
PubMed
Search for other papers by Matilde Monti in
Google Scholar
PubMed
Chiara Romualdi
Chiara Romualdi
Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy
Search for other papers by Chiara Romualdi in
Google Scholar
PubMed
Search for other papers by Chiara Romualdi in
Google Scholar
PubMed
Alessandro Vanoli
Alessandro Vanoli
Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy
Search for other papers by Alessandro Vanoli in
Google Scholar
PubMed
Search for other papers by Alessandro Vanoli in
Google Scholar
PubMed
Emanuela Vicari
Emanuela Vicari
Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy
Search for other papers by Emanuela Vicari in
Google Scholar
PubMed
Search for other papers by Emanuela Vicari in
Google Scholar
PubMed
Enrico Solcia
Enrico Solcia
Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy
Search for other papers by Enrico Solcia in
Google Scholar
PubMed
Search for other papers by Enrico Solcia in
Google Scholar
PubMed
Carlo Capella
Carlo Capella
Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy
Search for other papers by Carlo Capella in
Google Scholar
PubMed
Search for other papers by Carlo Capella in
Google Scholar
PubMed
Fausto Sessa
Fausto Sessa
Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy
Search for other papers by Fausto Sessa in
Google Scholar
PubMed
Search for other papers by Fausto Sessa in
Google Scholar
PubMed
Stefano La Rosa
Stefano La Rosa
Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy
Search for other papers by Stefano La Rosa in
Google Scholar
PubMed
Search for other papers by Stefano La Rosa in
Google Scholar
PubMed
Introduction High-grade (or poorly differentiated) gastroenteropancreatic (GEP) neuroendocrine carcinomas (NECs) are aggressive cancers with a high propensity for distant metastases. Like the more frequent pulmonary counterparts, they have
Andrew McDonald
Andrew McDonald
Winship Cancer Institute at Emory University, Atlanta, Georgia, USA
Search for other papers by Andrew McDonald in
Google Scholar
PubMed
Search for other papers by Andrew McDonald in
Google Scholar
PubMed
Vaidehi Avadhani
Vaidehi Avadhani
Grady Memorial Hospital, Atlanta, Georgia, USA
Search for other papers by Vaidehi Avadhani in
Google Scholar
PubMed
Search for other papers by Vaidehi Avadhani in
Google Scholar
PubMed
Gabriela Oprea-Ilies
Gabriela Oprea-Ilies
Grady Memorial Hospital, Atlanta, Georgia, USA
Search for other papers by Gabriela Oprea-Ilies in
Google Scholar
PubMed
Search for other papers by Gabriela Oprea-Ilies in
Google Scholar
PubMed
Katerina Zakka
Katerina Zakka
Winship Cancer Institute at Emory University, Atlanta, Georgia, USA
Search for other papers by Katerina Zakka in
Google Scholar
PubMed
Search for other papers by Katerina Zakka in
Google Scholar
PubMed
Gregory B Lesinski
Gregory B Lesinski
Winship Cancer Institute at Emory University, Atlanta, Georgia, USA
Search for other papers by Gregory B Lesinski in
Google Scholar
PubMed
Search for other papers by Gregory B Lesinski in
Google Scholar
PubMed
Olumide B Gbolahan
Olumide B Gbolahan
Winship Cancer Institute at Emory University, Atlanta, Georgia, USA
Search for other papers by Olumide B Gbolahan in
Google Scholar
PubMed
Search for other papers by Olumide B Gbolahan in
Google Scholar
PubMed
Olatunji Alese
Olatunji Alese
Winship Cancer Institute at Emory University, Atlanta, Georgia, USA
Search for other papers by Olatunji Alese in
Google Scholar
PubMed
Search for other papers by Olatunji Alese in
Google Scholar
PubMed
as neuroendocrine carcinoma (NEC). There is an inverse correlation between overall survival (OS) and tumor grade, with HG NEC having the worst prognosis among GEP-NEN subtypes ( Klimstra et al. 2019 ). GEP-NECs have an aggressive natural history
M Heetfeld
M Heetfeld
Search for other papers by M Heetfeld in
Google Scholar
PubMed
Search for other papers by M Heetfeld in
Google Scholar
PubMed
C N Chougnet
C N Chougnet
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
Search for other papers by C N Chougnet in
Google Scholar
PubMed
Search for other papers by C N Chougnet in
Google Scholar
PubMed
I H Olsen
I H Olsen
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
Search for other papers by I H Olsen in
Google Scholar
PubMed
Search for other papers by I H Olsen in
Google Scholar
PubMed
A Rinke
A Rinke
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
Search for other papers by A Rinke in
Google Scholar
PubMed
Search for other papers by A Rinke in
Google Scholar
PubMed
I Borbath
I Borbath
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
Search for other papers by I Borbath in
Google Scholar
PubMed
Search for other papers by I Borbath in
Google Scholar
PubMed
G Crespo
G Crespo
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
Search for other papers by G Crespo in
Google Scholar
PubMed
Search for other papers by G Crespo in
Google Scholar
PubMed
J Barriuso
J Barriuso
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
Search for other papers by J Barriuso in
Google Scholar
PubMed
Search for other papers by J Barriuso in
Google Scholar
PubMed
M Pavel
M Pavel
Search for other papers by M Pavel in
Google Scholar
PubMed
Search for other papers by M Pavel in
Google Scholar
PubMed
D O'Toole
D O'Toole
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
Search for other papers by D O'Toole in
Google Scholar
PubMed
Search for other papers by D O'Toole in
Google Scholar
PubMed
T Walter
T Walter
Department of Hepatology and Gastroenterology, Department of Nuclear Medicine, Department of Surgical Gastroenterology, Department of Internal Medicine, Department of Gastroenterology, Department of Medical Oncology, Department of Medical Oncology, Department of Clinical Medicine and Gastroenterology, Department of Hepatology and Gastroenterology, Charité University Hospital Berlin, Berlin, Germany
Search for other papers by T Walter in
Google Scholar
PubMed
Search for other papers by T Walter in
Google Scholar
PubMed
other Knowledge Network members
other Knowledge Network members
Search for other papers by other Knowledge Network members in
Google Scholar
PubMed
Search for other papers by other Knowledge Network members in
Google Scholar
PubMed
a Ki-67 index ranging from 20 to 55% and those with a Ki-67 index above 55%. According to the current World Health Organization (WHO) 2010 Classification, neuroendocrine carcinoma (NEC) is defined by both a poorly differentiated morphology (large
Mairéad G McNamara
Mairéad G McNamara
Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK
Division of Cancer Sciences, University of Manchester, Manchester, UK
Search for other papers by Mairéad G McNamara in
Google Scholar
PubMed
Division of Cancer Sciences, University of Manchester, Manchester, UK
Search for other papers by Mairéad G McNamara in
Google Scholar
PubMed
Jean-Yves Scoazec
Jean-Yves Scoazec
Department of Pathology, Gustave Roussy Cancer Campus, Villejuif, France
Université Paris Sud, Faculté de Médecine de Bicêtre, Le Kremlin-Bicêtre, France
Search for other papers by Jean-Yves Scoazec in
Google Scholar
PubMed
Université Paris Sud, Faculté de Médecine de Bicêtre, Le Kremlin-Bicêtre, France
Search for other papers by Jean-Yves Scoazec in
Google Scholar
PubMed
Thomas Walter
Thomas Walter
Department of Gastroenterology and Medical Oncology, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France
Search for other papers by Thomas Walter in
Google Scholar
PubMed
Search for other papers by Thomas Walter in
Google Scholar
PubMed
Introduction High grade neuroendocrine carcinomas (NECs) are usually defined by the combination of a poorly differentiated tumour cell morphology and evidence of high proliferative activity, evaluated either directly through the mitotic index
