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Charles E Massie Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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Inmaculada Spiteri Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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Helen Ross-Adams Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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Hayley Luxton Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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Jonathan Kay Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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Hayley C Whitaker Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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Mark J Dunning Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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Alastair D Lamb Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK
Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK
Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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Antonio Ramos-Montoya Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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Daniel S Brewer Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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Colin S Cooper Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK
Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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Rosalind Eeles Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK
Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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UK Prostate ICGC Group
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Anne Y Warren Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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Simon Tavaré Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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David E Neal Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK
Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK
Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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Andy G Lynch Cancer Research UK Cambridge Institute, Division of Genetics and Epidemiology, Department of Biological Sciences and School of Medicine, Royal Marsden NHS Foundation Trust, Departments of Pathology, Urology, Surgical Oncology, University of Cambridge, Cambridge, CB2 0RE, UK

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prostate cancer and AR signalling ( Ramos-Montoya et al . 2014 ). Herein, we characterise an epigenetic alteration at the promoter of the related HES5 gene, which has been recently reported in a panel of genes that showed promise as a prostate cancer

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-14-0454
Volume/Issue:
Volume 22: Issue 2
Open access
Sisi He Department of Molecular and Integrative Physiology, University of Illinois at Urbana Champaign, Urbana, Illinois, USA

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Liqian Ma Department of Molecular and Integrative Physiology, University of Illinois at Urbana Champaign, Urbana, Illinois, USA

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Amy E Baek Department of Molecular and Integrative Physiology, University of Illinois at Urbana Champaign, Urbana, Illinois, USA

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Anna Vardanyan Department of Molecular and Integrative Physiology, University of Illinois at Urbana Champaign, Urbana, Illinois, USA

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Varsha Vembar Department of Molecular and Integrative Physiology, University of Illinois at Urbana Champaign, Urbana, Illinois, USA

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Joy J Chen Department of Molecular and Integrative Physiology, University of Illinois at Urbana Champaign, Urbana, Illinois, USA

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Adam T Nelson Department of Molecular and Integrative Physiology, University of Illinois at Urbana Champaign, Urbana, Illinois, USA

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Joanna E Burdette Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois, USA
Cancer Center at Illinois, University of Illinois at Urbana Champaign, Urbana, Illinois, USA

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Erik R Nelson Department of Molecular and Integrative Physiology, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
Cancer Center at Illinois, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
Division of Nutritional Sciences, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois, USA
Carl R. Woese Institute for Genomic Biology, Anticancer Discovery from Pets to People Theme, University of Illinois at Urbana Champaign, Urbana, Illinois, USA

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Introduction It is expected that there will be approximately 22,530 new cases of ovarian cancer diagnosed in the USA in 2019, accounting for roughly 2.5% of all female cancers ( American Cancer Society 2019 ). Current therapeutic standard of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-18-0572
Volume/Issue:
Volume 26: Issue 7
Free access
James Yao University of Texas MD Anderson Cancer Center, Houston, Texas, USA

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Abhishek Garg Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA

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David Chen Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA

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Jaume Capdevila Vall d’Hebron University Hospital, Vall Hebron Institute of Oncology (VHIO), Autonomous University of Barcelona, Barcelona, Spain

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Paul Engstrom Fox Chase Cancer Center, Philadelphia, Pennsylvania, USA

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Rodney Pommier Oregon Health and Science University, Portland, Oregon, USA

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Eric Van Cutsem University Hospitals Gasthuisberg/Leuven and KU Leuven, Leuven, Belgium

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Simron Singh Odette Cancer Center, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada

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Nicola Fazio European Institute of Oncology, Milan, Italy

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Wei He Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA

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Markus Riester Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA

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Parul Patel Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA

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Maurizio Voi Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USA

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Michael Morrissey Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, USA

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Marianne Pavel University of Erlangen-Nuremberg, Erlangen, Germany

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Matthew Helmut Kulke Dana Farber Cancer Institute, Boston, Massachusetts, USA

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Communications 5 3518 . ( https://doi.org/10.1038/ncomms4518 ) 24670920 10.1038/ncomms4518 Frampton GM Fichtenholtz A Otto GA Wang K Downing SR He J Schnall-Levin M White J Sanford EM An P , et al . 2013 Development and validation of a clinical cancer

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-18-0332
Volume/Issue:
Volume 26: Issue 4
Open access
Y Capodanno Royal (Dick) School of Veterinary Studies and The Roslin Institute, University of Edinburgh, Midlothian, UK

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F O Buishand Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands

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L Y Pang Royal (Dick) School of Veterinary Studies and The Roslin Institute, University of Edinburgh, Midlothian, UK

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J Kirpensteijn Hill’s Pet Nutrition, Topeka, Kansas, USA

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J A Mol Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands

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D J Argyle Royal (Dick) School of Veterinary Studies and The Roslin Institute, University of Edinburgh, Midlothian, UK

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. The Notch pathway is overexpressed and active in 5-FU-resistant INS cells Analysis of gene expression had revealed that Notch pathway-related receptor, NOTCH2, and its target gene, HES1 were upregulated in both CM and canINS CSC-enriched spheres

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-17-0415
Volume/Issue:
Volume 25: Issue 2
Free access
Cristina L Ronchi
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Silviu Sbiera Endocrine and Diabetes Unit, Central Laboratory, Institute of Pathology, Comprehensive Cancer Center Mainfranken, Department of Internal Medicine I, University Hospital, University of Wuerzburg, Oberrduerrbacher-Strasse 6, 97080 Wuerzburg, Germany

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Barbara Altieri
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Sonja Steinhauer
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Vanessa Wild Endocrine and Diabetes Unit, Central Laboratory, Institute of Pathology, Comprehensive Cancer Center Mainfranken, Department of Internal Medicine I, University Hospital, University of Wuerzburg, Oberrduerrbacher-Strasse 6, 97080 Wuerzburg, Germany
Endocrine and Diabetes Unit, Central Laboratory, Institute of Pathology, Comprehensive Cancer Center Mainfranken, Department of Internal Medicine I, University Hospital, University of Wuerzburg, Oberrduerrbacher-Strasse 6, 97080 Wuerzburg, Germany

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Michaela Bekteshi
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Matthias Kroiss Endocrine and Diabetes Unit, Central Laboratory, Institute of Pathology, Comprehensive Cancer Center Mainfranken, Department of Internal Medicine I, University Hospital, University of Wuerzburg, Oberrduerrbacher-Strasse 6, 97080 Wuerzburg, Germany

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Martin Fassnacht
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Bruno Allolio
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several target genes, including the hairy enhancer of split ( HES ) family, the HES-related ( HEY ) family, and many others involved in apoptosis ( NFK2 , CDKN1A , BIRC5 /surviving, BCL2 ), cell cycle or proliferation ( CCND1 , DTX1 , p21 / WAF1

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-15-0163
Volume/Issue:
Volume 22: Issue 4
Free access
Xi Wei Department of Diagnostic and Therapeutic Ultrasonography, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

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Shang Cai Department of Oncology, Southern Research Institute and Cancer Cell Biology Program, the University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, USA
Department of Radiotherapy and Oncology, the Second Affiliated Hospital of Soochow University, Suzhou, China

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Rebecca J Boohaker Department of Oncology, Southern Research Institute and Cancer Cell Biology Program, the University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, USA

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Joshua Fried Department of Oncology, Southern Research Institute and Cancer Cell Biology Program, the University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, USA

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Ying Li The Third Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

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Linfei Hu Department of Thyroid Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

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Yi Pan Department of Thyroid Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

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Ruifen Cheng Department of Thyroid Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

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Sheng Zhang Department of Diagnostic and Therapeutic Ultrasonography, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

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Ye Tian Department of Radiotherapy and Oncology, the Second Affiliated Hospital of Soochow University, Suzhou, China

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Ming Gao Department of Thyroid Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

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Bo Xu Department of Oncology, Southern Research Institute and Cancer Cell Biology Program, the University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, USA
Department of Molecular Radiation Oncology, Key Laboratory of Breast Cancer Prevention and Therapy, Ministry of Education, National Clinical Research Center of Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

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tumor progression and metastasis ( Boohaker & Xu 2014 ). One critical element in the DDR pathway is lysine (K) acetyltransferase 5 (KAT5), which belongs to the MYST family of histone acetyltransferase ( Sun et al . 2010 ). Also known as Tip60, KAT5 is

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-18-0193
Volume/Issue:
Volume 26: Issue 1
Free access
Belinda J Petri Department of Biochemistry & Molecular Genetics, University of Louisville School of Medicine Louisville, Kentucky, USA

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Kellianne M Piell Department of Biochemistry & Molecular Genetics, University of Louisville School of Medicine Louisville, Kentucky, USA

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Ali E Wilt Department of Biochemistry & Molecular Genetics, University of Louisville School of Medicine Louisville, Kentucky, USA

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Alexa D Howser Department of Biochemistry & Molecular Genetics, University of Louisville School of Medicine Louisville, Kentucky, USA

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Laura Winkler Department of Biochemistry & Molecular Genetics, University of Louisville School of Medicine Louisville, Kentucky, USA

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Mattie R Whitworth Department of Biochemistry & Molecular Genetics, University of Louisville School of Medicine Louisville, Kentucky, USA

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Bailey L Valdes Department of Biochemistry & Molecular Genetics, University of Louisville School of Medicine Louisville, Kentucky, USA

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Norman L Lehman Department of Biochemistry & Molecular Genetics, University of Louisville School of Medicine Louisville, Kentucky, USA
Pathology and Laboratory Medicine, University of Louisville, Louisville, Kentucky, USA
The Brown Cancer Center, University of Louisville, Louisville, Kentucky, USA

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Brian F Clem Department of Biochemistry & Molecular Genetics, University of Louisville School of Medicine Louisville, Kentucky, USA
The Brown Cancer Center, University of Louisville, Louisville, Kentucky, USA

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Carolyn M Klinge Department of Biochemistry & Molecular Genetics, University of Louisville School of Medicine Louisville, Kentucky, USA
The Brown Cancer Center, University of Louisville, Louisville, Kentucky, USA
Center for Integrative Environmental Health Sciences (CIEHS), University of Louisville, Louisville, Kentucky, USA

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various cancers, e.g. gastric cancer ( Zhou et al. 2020 ), cervical cancer ( He et al. 2020 ), and ovarian cancer ( Pan et al. 2022 ). Overexpression of miR-145-5p in ovarian cancer cells reduced PSAT1 mRNA ( Pan et al. 2022 ). Cotransfection of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-23-0148
Volume/Issue:
Volume 30: Issue 11
Restricted access
S Leskelä
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E Honrado
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C Montero-Conde
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I Landa
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A Cascón
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R Letón
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P Talavera
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J M Cózar
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A Concha
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M Robledo
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C Rodríguez-Antona
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. Hustert E , Haberl M, Burk O, Wolbold R, He YQ, Klein K, Nuessler AC, Neuhaus P, Klattig J, Eiselt R et al. 2001 The genetic determinants of the CYP3A5 polymorphism. Pharmacogenetics 11 773 –779. Kamdem LK , Meineke I

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-07-0078
Volume/Issue:
Volume 14: Issue 3
Free access
Lei Gu Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Paraskevi Vogiatzi Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Martin Puhr Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Ayush Dagvadorj Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Jacqueline Lutz Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Amy Ryder Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Sankar Addya Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Paolo Fortina Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Carlton Cooper Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Benjamin Leiby Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Abhijit Dasgupta Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Terry Hyslop Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Lukas Bubendorf Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Kalle Alanen Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Tuomas Mirtti Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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Marja T Nevalainen Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
Cancer Biology, Medicina Sperimentale e Patologia, Biological Sciences, Pharmacy and Experimental Therapeutics, Institute for Pathology, Pathology, Urology, Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA

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prostate cancer will provide a rational basis for the development of effective therapies for advanced prostate cancer. Transcription factor (TF) Stat5 is critical for the growth of human prostate cancer. Stat5 belongs to the Stat gene family ( Ihle 2001

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-09-0328
Volume/Issue:
Volume 17: Issue 2
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Marc Lippman
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so much of my career path almost obvious and unavoidable in retrospect. I owe a great deal to my father. He was a remarkably gifted man. Some might say a polymath. He was a fine physician, a scholar, a renowned collector of African tribal art, a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-11-0341
Volume/Issue:
Volume 19: Issue 1
Free access