Search Results

You are looking at 1 - 6 of 6 items for :

Clear All
Restricted access

Isadora Pontes Cavalcante, Anna Vaczlavik, Ludivine Drougat, Claudimara Ferini Pacicco Lotfi, Karine Perlemoine, Christopher Ribes, Marthe Rizk-Rabin, Eric Clauser, Maria Candida Barisson Villares Fragoso, Jérôme Bertherat and Bruno Ragazzon

co-immunoprecipitation (co-IP) followed by mass spectrometry (MS) analysis (Kouranti I, Abdel Khalek W, Mazurkiewicz S, Pintard L, Jeunemaitre X & Clauser E, unpublished observations) suggest that ARMC5 interacts with Cullin3 (CUL3). CUL3 is a

Free access

H H Milioli, S Alexandrou, E Lim and C E Caldon

complexes. Cyclin E1 monomers can be ubiquitinated by Cul3 and SPOP and cyclin E1/E2 monomers by SCF Skp2 complexes, leading to proteosomal degradation. Cyclin E-CDK2 complexes can be inhibited by CDK inhibitors p21 Waf1/Cip1 , p27 Kip1 , and p57 Kip2 , but

Free access

Donata Vitagliano, Valentina De Falco, Anna Tamburrino, Sabrina Coluzzi, Giancarlo Troncone, Gennaro Chiappetta, Fortunato Ciardiello, Giampaolo Tortora, James A Fagin, Anderson J Ryan, Francesca Carlomagno and Massimo Santoro

, CUL3 , and SKP2 (G 1 phase and G 1 /S transition); ABL1 , MCM2 , MCM3 , MCM4 , MCM5 , PCNA , RPA3 , SUMO1 , and UBE1 (S phase and DNA replication); ANAPC2 , ANAPC4 , DIRAS3 , BCCIP , BIRC5 , CCNB1 , CCNG1 , CCNH , CCNT1 , CCNT2

Free access

Naima Abidi and Dimitris P Xirodimas

, Tetzlaff et al . 2004 ). Increase in the levels of CUL3 and CUL4A was also associated with tumour progression in breast cancers, but the mechanism for this upregulation is currently unclear ( Haagenson et al . 2012 ). Increase in mRNA levels of CUL7 was

Free access

Yoshiaki Onodera, Hozumi Motohashi, Kiyoshi Takagi, Yasuhiro Miki, Yukiko Shibahara, Mika Watanabe, Takanori Ishida, Hisashi Hirakawa, Hironobu Sasano, Masayuki Yamamoto and Takashi Suzuki

, 2011 , Zhang et al . 2010 , Lister et al . 2011 ), and Loignon et al . (2009) reported that Cullin 3 ubiquitin E3 ligase ( CUL3 )-silenced MCF7 cells had increased NRF2 protein levels and exhibited high resistance to both doxorubicin and

Free access

Fidéline Bonnet-Serrano and Jérôme Bertherat

-cell apoptosis. ARMC5-binding partners were further investigated by yeast-2-hybrid assay, and identified actors in pathways regulating both cell cycling (for example, CUL3) and apoptosis (for example, DAPK1) as well as ARMC5 itself, suggesting multimerization