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Trisha Dwight
Trisha Dwight
Cancer Genetics, Kolling Institute, Royal North Shore Hospital, Sydney, New South Wales, Australia
The University of Sydney, Sydney, New South Wales, Australia
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The University of Sydney, Sydney, New South Wales, Australia
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Aidan Flynn
Aidan Flynn
The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen N, Denmark
Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen N, Denmark
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Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen N, Denmark
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Kaushalya Amarasinghe
Kaushalya Amarasinghe
The Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
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Diana E Benn
Diana E Benn
Cancer Genetics, Kolling Institute, Royal North Shore Hospital, Sydney, New South Wales, Australia
The University of Sydney, Sydney, New South Wales, Australia
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The University of Sydney, Sydney, New South Wales, Australia
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Richard Lupat
Richard Lupat
The Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
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Jason Li
Jason Li
The Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
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Daniel L Cameron
Daniel L Cameron
The Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia
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Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia
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Annette Hogg
Annette Hogg
The Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
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Shiva Balachander
Shiva Balachander
The Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
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Ida L M Candiloro
Ida L M Candiloro
Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia
The Department of Pathology, University of Melbourne, Parkville, Victoria, Australia
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The Department of Pathology, University of Melbourne, Parkville, Victoria, Australia
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Stephen Q Wong
Stephen Q Wong
The Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
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Bruce G Robinson
Bruce G Robinson
Cancer Genetics, Kolling Institute, Royal North Shore Hospital, Sydney, New South Wales, Australia
The University of Sydney, Sydney, New South Wales, Australia
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The University of Sydney, Sydney, New South Wales, Australia
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Anthony T Papenfuss
Anthony T Papenfuss
The Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia
The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia
The Department of Mathematics and Statistics, University of Melbourne, Parkville, Victoria, Australia
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Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia
The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia
The Department of Mathematics and Statistics, University of Melbourne, Parkville, Victoria, Australia
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Anthony J Gill
Anthony J Gill
The University of Sydney, Sydney, New South Wales, Australia
Cancer Diagnosis and Pathology Group, Kolling Institute, Royal North Shore Hospital, Sydney, New South Wales, Australia
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Cancer Diagnosis and Pathology Group, Kolling Institute, Royal North Shore Hospital, Sydney, New South Wales, Australia
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Alexander Dobrovic
Alexander Dobrovic
Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia
The Department of Pathology, University of Melbourne, Parkville, Victoria, Australia
School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia
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The Department of Pathology, University of Melbourne, Parkville, Victoria, Australia
School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia
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Rodney J Hicks
Rodney J Hicks
The Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia
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The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia
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Roderick J Clifton-Bligh
Roderick J Clifton-Bligh
Cancer Genetics, Kolling Institute, Royal North Shore Hospital, Sydney, New South Wales, Australia
The University of Sydney, Sydney, New South Wales, Australia
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The University of Sydney, Sydney, New South Wales, Australia
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Richard W Tothill
Richard W Tothill
The Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia
The Department of Pathology, University of Melbourne, Parkville, Victoria, Australia
The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia
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The Department of Pathology, University of Melbourne, Parkville, Victoria, Australia
The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia
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( Tischler et al . 2017 ). Activation of TERT as a result of promoter mutations (specifically, chr5:1295228C > T and chr5:1295250C > T) were initially found in melanoma ( Horn et al . 2013 ) and have subsequently been shown to be one of the most
Johan O Paulsson
Johan O Paulsson
Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital CCK, Stockholm, Sweden
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Ninni Mu
Ninni Mu
Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital CCK, Stockholm, Sweden
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Ivan Shabo
Ivan Shabo
Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Department of Breast, Endocrine Tumours and Sarcoma, Karolinska University Hospital, Stockholm, Sweden
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Department of Breast, Endocrine Tumours and Sarcoma, Karolinska University Hospital, Stockholm, Sweden
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Na Wang
Na Wang
Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital CCK, Stockholm, Sweden
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Jan Zedenius
Jan Zedenius
Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Department of Breast, Endocrine Tumours and Sarcoma, Karolinska University Hospital, Stockholm, Sweden
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Department of Breast, Endocrine Tumours and Sarcoma, Karolinska University Hospital, Stockholm, Sweden
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Catharina Larsson
Catharina Larsson
Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital CCK, Stockholm, Sweden
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C Christofer Juhlin
C Christofer Juhlin
Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital CCK, Stockholm, Sweden
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Introduction The telomerase enzyme consists of a protein component with reverse transcriptase activity, encoded by the telomerase reverse transcriptase ( TERT ) gene ( Cong et al. 2002 ). Telomerase activation is a hallmark of malignant
Tiantian Liu
Tiantian Liu
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Taylor C Brown
Taylor C Brown
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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C Christofer Juhlin
C Christofer Juhlin
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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Adam Andreasson
Adam Andreasson
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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Na Wang
Na Wang
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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Martin Bäckdahl
Martin Bäckdahl
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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James M Healy
James M Healy
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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Manju L Prasad
Manju L Prasad
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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Reju Korah
Reju Korah
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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Tobias Carling
Tobias Carling
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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Dawei Xu
Dawei Xu
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Catharina Larsson
Catharina Larsson
Department of Medicine-Solna, Yale Endocrine Neoplasia Laboratory, Department of Surgery, Departments of Oncology-Pathology, Molecular Medicine and Surgery, Department of Pathology, Karolinska Institutet, Karolinska University Hospital CMM, SE-171 76 Stockholm, Sweden
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telomerase reverse transcriptase (TERT), a catalytic subunit of the telomerase enzyme complex. As the de-repression of TERT gene transcription is intimately coupled with the acquisition of telomerase activity in transformed cells, regulatory mechanisms
Matthias S Dettmer
Matthias S Dettmer
Institute of Pathology, Division of Nuclear Medicine, Department of Neuropathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Bern, Murtenstrasse 31, 3010 Bern, Switzerland
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Anja Schmitt
Anja Schmitt
Institute of Pathology, Division of Nuclear Medicine, Department of Neuropathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Bern, Murtenstrasse 31, 3010 Bern, Switzerland
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Hans Steinert
Hans Steinert
Institute of Pathology, Division of Nuclear Medicine, Department of Neuropathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Bern, Murtenstrasse 31, 3010 Bern, Switzerland
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David Capper
David Capper
Institute of Pathology, Division of Nuclear Medicine, Department of Neuropathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Bern, Murtenstrasse 31, 3010 Bern, Switzerland
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Holger Moch
Holger Moch
Institute of Pathology, Division of Nuclear Medicine, Department of Neuropathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Bern, Murtenstrasse 31, 3010 Bern, Switzerland
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Paul Komminoth
Paul Komminoth
Institute of Pathology, Division of Nuclear Medicine, Department of Neuropathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Bern, Murtenstrasse 31, 3010 Bern, Switzerland
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Aurel Perren
Aurel Perren
Institute of Pathology, Division of Nuclear Medicine, Department of Neuropathology, Institute of Surgical Pathology, Institute of Surgical Pathology, University of Bern, Murtenstrasse 31, 3010 Bern, Switzerland
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transcriptase ( TERT ) gene, which encodes for the catalytic subunit of telomerase, is implicated in tumorigenesis and cell immortalization. The two promoter mutations C228T and C250T were recently reported in human melanomas and other human cancer types
Vicente Rodrigues Marczyk
Vicente Rodrigues Marczyk
Thyroid Unit, Endocrine division, Hospital de Clínicas de Porto Alegre (HCPA), Brazil
Medical School, Universidade Federal do Rio Grande do Sul (UFRGS), Brazil
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Medical School, Universidade Federal do Rio Grande do Sul (UFRGS), Brazil
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Ana Luiza Maia
Ana Luiza Maia
Thyroid Unit, Endocrine division, Hospital de Clínicas de Porto Alegre (HCPA), Brazil
Medical School, Universidade Federal do Rio Grande do Sul (UFRGS), Brazil
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Medical School, Universidade Federal do Rio Grande do Sul (UFRGS), Brazil
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Iuri Martin Goemann
Iuri Martin Goemann
Thyroid Unit, Endocrine division, Hospital de Clínicas de Porto Alegre (HCPA), Brazil
Medical School, Universidade Federal do Rio Grande do Sul (UFRGS), Brazil
Medical School, Universidade do Vale do Rio dos Sinos (UNISINOS), Brazil
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Medical School, Universidade Federal do Rio Grande do Sul (UFRGS), Brazil
Medical School, Universidade do Vale do Rio dos Sinos (UNISINOS), Brazil
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Introduction The catalytic subunit of the telomerase enzyme is encoded by the telomerase reverse transcriptase ( TERT ) gene and is crucial for telomerase activity. Two hotspot mutations affecting the promoter region of TERT were discovered
Soomin Ahn
Soomin Ahn
Department of Pathology, Ewha Womans University School of Medicine, Seoul, Korea
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Tae Hyuk Kim
Tae Hyuk Kim
Division of Endocrinology and Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
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Sun Wook Kim
Sun Wook Kim
Division of Endocrinology and Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
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Chang Seok Ki
Chang Seok Ki
Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
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Hye Won Jang
Hye Won Jang
Department of Medical Education, Sungkyunkwan University School of Medicine, Seoul, Korea
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Jee Soo Kim
Jee Soo Kim
Division of Breast and Endocrine Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
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Jung Han Kim
Jung Han Kim
Division of Breast and Endocrine Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
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Jun-Ho Choe
Jun-Ho Choe
Division of Breast and Endocrine Surgery, Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
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Jung Hee Shin
Jung Hee Shin
Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
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Soo Yeon Hahn
Soo Yeon Hahn
Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
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Young Lyun Oh
Young Lyun Oh
Department of Pathology and Translational genomics, Sungkyunkwan University School of Medicine, Seoul, Korea
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Jae Hoon Chung
Jae Hoon Chung
Division of Endocrinology and Metabolism, Department of Medicine, Thyroid Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
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frequency of PD-L1 expression in various thyroid cancers and the relationship between PD-L1 expression and clinicopathologic factors including BRAF , TERT promoter status and disease progression were evaluated. Materials and methods Case
Rengyun Liu
Rengyun Liu
Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology, Diabetes and Metabolism, The Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA
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Mingzhao Xing
Mingzhao Xing
Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology, Diabetes and Metabolism, The Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA
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Introduction Telomerase reverse transcriptase in human cancer Telomerase reverse transcriptase (TERT) is the catalytic protein subunit of telomerase, which, together with an integral RNA subunit and several species-specific assessor proteins
Young Shin Song
Young Shin Song
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea
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Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea
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Seong-Keun Yoo
Seong-Keun Yoo
Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Korea
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Hwan Hee Kim
Hwan Hee Kim
Center for Medical Innovation, Seoul National University Hospital, Seoul, Korea
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Gyeongseo Jung
Gyeongseo Jung
Center for Medical Innovation, Seoul National University Hospital, Seoul, Korea
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Ah-Reum Oh
Ah-Reum Oh
Department of Biochemistry, Lee Gil Ya Cancer and Diabetes Institute, GAIHST, Gachon University College of Medicine, Incheon, Korea
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Ji-Young Cha
Ji-Young Cha
Department of Biochemistry, Lee Gil Ya Cancer and Diabetes Institute, GAIHST, Gachon University College of Medicine, Incheon, Korea
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Su-jin Kim
Su-jin Kim
Department of Surgery, Seoul National University College of Medicine, Seoul, Korea
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Sun Wook Cho
Sun Wook Cho
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
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Kyu Eun Lee
Kyu Eun Lee
Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Korea
Department of Surgery, Seoul National University College of Medicine, Seoul, Korea
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Department of Surgery, Seoul National University College of Medicine, Seoul, Korea
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Jeong-Sun Seo
Jeong-Sun Seo
Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Korea
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Young Joo Park
Young Joo Park
Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Korea
Center for Medical Innovation, Seoul National University Hospital, Seoul, Korea
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Genomic Medicine Institute, Medical Research Center, Seoul National University, Seoul, Korea
Center for Medical Innovation, Seoul National University Hospital, Seoul, Korea
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Introduction Telomerase reverse transcriptase ( TERT ) has a canonical role maintaining telomere length and the nontelomeric function, which can regulate the expression of various genes involved in cell proliferation and cellular signaling
Rengyun Liu
Rengyun Liu
Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology, Diabetes and Metabolism, The Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA
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Mingzhao Xing
Mingzhao Xing
Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology, Diabetes and Metabolism, The Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA
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required to achieve this. Two recently discovered mutations in the promoter of the gene for telomerase reverse transcriptase (TERT) in thyroid cancer show promise in this regard – chr5:1 295 228C>T and chr5:1 295 250C>T (termed herein as C228T and C250T
Xiaoli Liu
Xiaoli Liu
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Justin Bishop
Justin Bishop
Laboratory for Cellular and Molecular Thyroid Research, Department of Pathology, Departments of Anatomic Pathology and Neuro-Oncology, Department of Otolaryngology–Head and Neck Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Department of Pathology, Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA
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Yuan Shan
Yuan Shan
Laboratory for Cellular and Molecular Thyroid Research, Department of Pathology, Departments of Anatomic Pathology and Neuro-Oncology, Department of Otolaryngology–Head and Neck Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Department of Pathology, Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA
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Sara Pai
Sara Pai
Laboratory for Cellular and Molecular Thyroid Research, Department of Pathology, Departments of Anatomic Pathology and Neuro-Oncology, Department of Otolaryngology–Head and Neck Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Department of Pathology, Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA
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Dingxie Liu
Dingxie Liu
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Avaniyapuram Kannan Murugan
Avaniyapuram Kannan Murugan
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Hui Sun
Hui Sun
Laboratory for Cellular and Molecular Thyroid Research, Department of Pathology, Departments of Anatomic Pathology and Neuro-Oncology, Department of Otolaryngology–Head and Neck Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Department of Pathology, Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA
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Adel K El-Naggar
Adel K El-Naggar
Laboratory for Cellular and Molecular Thyroid Research, Department of Pathology, Departments of Anatomic Pathology and Neuro-Oncology, Department of Otolaryngology–Head and Neck Surgery, Jilin Provincial Key Laboratory of Surgical Translational Medicine, Department of Pathology, Division of Endocrinology and Metabolism, Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA
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Mingzhao Xing
Mingzhao Xing
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telomerase reverse transcriptase (TERT). Promoter mutations in the TERT gene on chromosome 5 have recently been reported in melanomas ( Horn et al . 2013 , Huang et al . 2013 ). Two TERT promoter mutations, 1 295 228 C>T and 1 295 250 C>T (termed C228T
